Organic Chemistry Synthesis Challenge 1

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  • Опубліковано 11 вер 2024
  • Need some organic chemistry practice? Here's a tricky synthesis to try!
    Try all of the organic chemistry practice problems: bit.ly/ProfDave...
    Organic Chemistry Tutorials: bit.ly/ProfDave...
    EMAIL► ProfessorDaveExplains@gmail.com
    PATREON► / professordaveexplains
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КОМЕНТАРІ • 101

  • @Laura-vy5ss
    @Laura-vy5ss 3 роки тому +39

    i am too tired to sit on my desk because of severe depression. because of your videos (wich i can watch in bed) i´m still learning. you explain everything perfectly short and on point. thank you so much

    • @enoughnonymity
      @enoughnonymity Рік тому +2

      hi sweetheart how are you feeling? depression is tough

    • @laura18700
      @laura18700 Рік тому +4

      @@enoughnonymity thanks for asking I'm smiling again bc i passed my exam :)

    • @matildahchishimba8142
      @matildahchishimba8142 Рік тому +7

      Whenever I'm depressed, I fail to do a single thing, idk, you're just incredible 😔❤️

    • @ghyzig
      @ghyzig 9 місяців тому +1

      hi, hope ur feeling better now. love

    • @myles.a
      @myles.a 9 місяців тому +1

      I hope you are feeling better now :) I am in the same boat, watching these videos from my bed. Tomorrow morning I have my organic chemistry final, yet I can't bring myself up to study for it properly. And i haven't seen my friends or anyone for days because I've been holed up in my room. Not even my roommates who literally live in the same house as me. I haven't even eaten anything in almost 30 hours but I can't get out of bed no matter how painful my migraine is or how hungry I am.
      Depression really really really sucks. It deprives us of so much in our lives. I would never wish it upon anyone. I hope everyone dealing with depression finds a way out of that darkness. ❤

  • @tonystark6997
    @tonystark6997 4 роки тому +40

    Where is "he knows a lot about science stuff! Professor Dave explains"??

    • @iliyanovslounge
      @iliyanovslounge 4 роки тому +2

      I guess he just forgot to add it in aha

    • @shreyaskrishna6038
      @shreyaskrishna6038 4 роки тому +4

      That intro is not used for vedios where he solves problems

    • @iliyanovslounge
      @iliyanovslounge 4 роки тому +2

      @@shreyaskrishna6038 I was going to say that actually. that for his tutorials he puts that intro but for practices/tests etc.. he doesnt use it.

  • @benscrafield9575
    @benscrafield9575 4 роки тому +7

    This is one of my pet peeves - drawing absolute stereochemistry when what is intended is relative stereochemistry. The straight bold/dashed bonds are a useful convention for what you want to draw, but simply writing (rac) or (+-) would also suffice. The question you have actually drawn is much harder to tackle because the solution necessarily involves a desymmetrisation, using e.g. a chiral Lewis acid in much the same way as a Jacobsen kinetic resolution but with CN.

  • @abhayr2070
    @abhayr2070 4 роки тому +27

    Why's Chris Evans teaching me organic chemistry?

  • @giovannirafael5351
    @giovannirafael5351 4 роки тому +4

    I found this channel while searching for Calculus and now I'm really interested in almost everything in it.

  • @karanlalwani5410
    @karanlalwani5410 4 роки тому +6

    Loving these new organic challenges Dave!! You are amazing

  • @thejuniorastrophysicist
    @thejuniorastrophysicist 4 роки тому +7

    We miss your intro and your awesome hair!!

  • @ScienceGeek23
    @ScienceGeek23 4 роки тому +2

    Brilliant video as always! I greatly appreciate your clear explanations. Super helpful!

  • @daphenomenalz4100
    @daphenomenalz4100 4 роки тому +5

    Thank you very much, your organic chemistry videos have helped me a lot in building my basics and now i am able to solve even complex problems. Thank you very much🙂🙂🙂🙏🙏🙏🙏🙏🙏🙏🙏🙏

  • @ili1905
    @ili1905 4 роки тому +6

    Thanks a lot for the organic chemistry practice it has helped me a lot!

  • @PunmasterSTP
    @PunmasterSTP 2 роки тому +1

    Synthesis challenge? More like "Dave's the best there is!" Thanks again for so many wonderful videos.

  • @Ps3COD4Fan
    @Ps3COD4Fan 4 роки тому +12

    I'm not taking Ochem anymore, just wanted to bring my PTSD back a bit

    • @ahmadrashid4853
      @ahmadrashid4853 4 роки тому +1

      This asmr will help you fit back into society
      m.ua-cam.com/video/3CXZdK6ikMA/v-deo.html

    • @Purpose_Porpoise
      @Purpose_Porpoise 4 роки тому +1

      I'm taking 2 in the fall. Trying not to get too comfortable.

    • @Ps3COD4Fan
      @Ps3COD4Fan 4 роки тому +1

      @@ahmadrashid4853 gold

    • @Ps3COD4Fan
      @Ps3COD4Fan 4 роки тому +1

      @@Purpose_Porpoise you're taking two ochem classes? Like lab and the lecture? if so ochem isn't bad, I got As in all my courses but it requires a LOT of practice. Try subscribing to Clutch Ochem, just google it, money's worth it

    • @Purpose_Porpoise
      @Purpose_Porpoise 4 роки тому +1

      @@Ps3COD4Fan Sorry, I typed that incorrectly. I meant I'm taking ochem 2 in fall. Forgot to put the "ochem" part in my first comment. I might be taking ochem lab along w/ it, so you technically aren't wrong.

  • @MatthewsPersonal
    @MatthewsPersonal 4 роки тому +1

    Easiest sub in a long time. Great work Dave! :D

  • @bhavika.jethani2282
    @bhavika.jethani2282 4 роки тому +1

    Just one?? There should be more such questions like this. It's fun solving such questions.

  • @513morris
    @513morris 4 роки тому +7

    I think I'm in the wrong class.

  • @harmanpreetsingh3844
    @harmanpreetsingh3844 4 роки тому +1

    Very nice explanation. Please make videos regarding stereochemistry and about asymmetric synthesis. It would help me a lot for asymmetric synthesis.

  • @anjanagopinadh
    @anjanagopinadh 4 роки тому +1

    Thnkyu sir😊 expect more challenges frm organic synthesis.

  • @andreameigs1261
    @andreameigs1261 Рік тому

    If you're using CN- don't you have to actually use something like HCN? In that case, why would the H on the oxygen come from the solvent (polar protic?) instead of from the HCN?

  • @thabolikotsi5765
    @thabolikotsi5765 4 роки тому +1

    Professor I study Mathematics but because of you I passed my time dilation physics test

  • @cSoLo
    @cSoLo 6 місяців тому

    For the first step can I use Br2,H2O to create a trans configuration?

  • @thychenghouy
    @thychenghouy 4 роки тому +1

    Which sugar are not sweet on monosaccharide and disaccharide? Help tell me 🙏🏻😊

  • @quintonwilson8565
    @quintonwilson8565 4 роки тому +3

    Clever mechanism, I initially thought to do halogenation of the double bond and then two sn2.

    • @PG-qn8od
      @PG-qn8od 4 роки тому +1

      oh man me too, I havent watched the video yet, but reading your response it seems like i was wrong

    • @nickrommel3752
      @nickrommel3752 4 роки тому +1

      Quinton Wilson I believe that if you halogenated the alkene with something like Br2 in a radical mechanism you would get a mix of stereoisomers.

  • @juanmunoz-luna5778
    @juanmunoz-luna5778 4 роки тому +1

    Nice little review

  • @prettyfaerie7
    @prettyfaerie7 Рік тому

    love the synthesis practice problems!

  • @WetDoggo
    @WetDoggo 4 роки тому +3

    Hey professor Dave,
    I'm really interested in organic chemistry, can you please make a series explaining some basic reactions like this?
    And please explain everything important to know, so it's easy to really understand.
    Thanks so much

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  4 роки тому +8

      That's literally the first thing I ever did on the whole channel. Check my organic chemistry playlist.

    • @WetDoggo
      @WetDoggo 4 роки тому +2

      @@ProfessorDaveExplains thanks

  • @muhimmanmuhtadi6134
    @muhimmanmuhtadi6134 4 роки тому +1

    Why the nitrile doesn't reduced by NaH? And what reducing agent could reduce nitrile to amine?

  • @cygnustsp
    @cygnustsp 4 роки тому +1

    Dave this is great, thank you

  • @mczeljk
    @mczeljk 4 роки тому +2

    Dave, won‘t the introduction of the cyanide group result in a racemic mixture?

  • @durveshwagh6382
    @durveshwagh6382 4 роки тому +1

    Hey Dave! love from India

  • @glokta1
    @glokta1 4 роки тому +1

    Nice! But, isn't the deprotonation step through NaH not required because we never introduced a proton-source in the reaction?

  • @anonismust
    @anonismust 4 роки тому +3

    2 dislikes from the frat earthers..
    I mean flat earthers

  • @Felixkeeg
    @Felixkeeg 4 роки тому +1

    Nice one! Say, is there a way to send you problems like this one (+solution of course) to be discussed here?

  • @alexanderoneill2612
    @alexanderoneill2612 4 роки тому +1

    Loved this

  • @Noldor97
    @Noldor97 4 роки тому +1

    nice i knew it, was thinking about it for one minute and i did know the answer :D

  • @bryancadena96
    @bryancadena96 4 роки тому +1

    These are great!

  • @alexg91024
    @alexg91024 4 роки тому +1

    Any plans for any future debates?

  • @Looney2ing
    @Looney2ing 4 роки тому +2

    Don't look at this in a public place, a Karen will getyou arrested. No clue what this means though. I'm a simple mechanical engineer.

  • @gardenmenuuu
    @gardenmenuuu 4 роки тому +2

    hey professor how do u know everything?Seriously?please reply

  • @hywelthomas7864
    @hywelthomas7864 3 роки тому

    Enjoyed the video. This is being picky but wouldn't you just get a 50:50 yield of 2 diastereoisomers following the addition of the cyanide nucleophile? Would you possibly be able to do a video on how to plan a more stereoselective reaction?

  • @whitneykaye
    @whitneykaye 4 роки тому +1

    Thank you 😁

  • @shaistaluqman2262
    @shaistaluqman2262 4 роки тому +1

    You should do a video about the new largest star in the universe, Stephenson 2-18

    • @513morris
      @513morris 4 роки тому +1

      *largest star known

  • @drtao8325
    @drtao8325 Рік тому

    I thought about using Br2, as that forms trans stereochemistry, and then I thought about reacting an alkoxide with the Br on the bottom after CN with the top? idk if that would work but it makes sense to me

  • @ramakrishnabingina796
    @ramakrishnabingina796 4 роки тому +1

    Its very nice video

  • @jbirdmax
    @jbirdmax 4 роки тому +1

    Oh! Oh! Umm, yes?

  • @drowsyclay7678
    @drowsyclay7678 4 роки тому +1

    Hey Dave are u somehow associated with edurev exam app as they are using your videos

  • @jimwatchyyc
    @jimwatchyyc 4 роки тому +2

    A much improved hair cut, easier to take you seriously now.

  • @ninjanahja8421
    @ninjanahja8421 3 роки тому

    Q: Why is mCPBA putting the Epoxide on dashes and not wedges already?

  • @abid5187
    @abid5187 4 роки тому +1

    You from

  • @jacksonmajor2663
    @jacksonmajor2663 Рік тому

    bro my dumbass made the alkyl halide I thought it all had to come from the starting material. Here's how I did it can anyone tell me if its correct? I used NBS in hv on the starting material, then I used LDA as a bulky base. Then I did O3 in SMe2. Then I took the three carbon product from that reaction and reduced with NaBH4 in ethanol. Then I used XS HBr. The I used 1 eq LDA. Can anyone tell me if this is correct?

  • @babarazamsucks
    @babarazamsucks 4 роки тому +1

    Fi

  • @fernandocaceres123
    @fernandocaceres123 4 роки тому +1

    Very informative, and handsome too ;)

  • @ros375
    @ros375 11 місяців тому

    Allyl bromide, not vinyl :)

  • @rishigautam6992
    @rishigautam6992 4 роки тому +1

    Hei Dave long time ago

  • @stevencorey7623
    @stevencorey7623 4 роки тому +2

    I hope kent Hovind sees this lol

  • @hussainsadliwala2767
    @hussainsadliwala2767 4 роки тому +4

    First comment

    • @hal5530
      @hal5530 4 роки тому +5

      I guess you haven't even watched the video

  • @yashsingh3562
    @yashsingh3562 4 роки тому +1

    that's basic JEE problem 💁‍♂💁‍♂🧘‍♂🧘‍♂

  • @Dharun-ge2fo
    @Dharun-ge2fo 8 місяців тому +1

    Didn't know ranbir kapoor is teaching chemistry.

    • @Yesuuh
      @Yesuuh Місяць тому

      thats not ranbir kapoor, hes a bollywood actor. This guy is from america

  • @prameshgurav7586
    @prameshgurav7586 10 місяців тому

    How do you take that oxygen on their in dashes?

    • @prameshgurav7586
      @prameshgurav7586 10 місяців тому

      And what is MCPBA?🤔 This haven't teach us in our class that's why I don't know about that.

    • @prameshgurav7586
      @prameshgurav7586 10 місяців тому

      Sir can you please make detailed video on this,I don't understand properly,if there you have added NaH then where it attack on the molecule?

  • @user-lu5it7iw6l
    @user-lu5it7iw6l Рік тому

    sigh

  • @ludwigludwig3515
    @ludwigludwig3515 3 роки тому

    I knew it. But i am german Dr. Chem.

  • @kilesprofit8917
    @kilesprofit8917 4 роки тому +1

    what is your tattoo?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  4 роки тому +1

      check out "ask professor dave #3"

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  4 роки тому +4

      Um, he asked what my tattoo is, and that video explains what my tattoo is. You're an enormous tool.

    • @kilesprofit8917
      @kilesprofit8917 4 роки тому +1

      @@ProfessorDaveExplains ok thanks

    • @michaelmann8800
      @michaelmann8800 4 роки тому +1

      @@user-le7ny8bq1l Have you actually debunked anything? Or is your handle just wishful "thinking?"

    • @michaelmann8800
      @michaelmann8800 4 роки тому +1

      @@user-le7ny8bq1l I can honestly think of no nobler way to "get more money" than to dispense KNOWLEDGE. Spending one's time trying to "debunk" knowledge is a truly foolish endeavor.

  • @ski.7
    @ski.7 4 роки тому

    I'm starting prof. Dave syndicate (A team that supports sir's channel to grow by sharing or etc (if we can't support on patron let's support in this way) :) ) let's make a discord channel or insta page to make sir more famous and share knowledge
    #prof.davesyndicate like this comment if you agree