Climbing Defects In Drosophila Model Of Neurodegenerative Disorders

Watch the Full Video at www.jove.com/v....
Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders - a 2 minute Preview of the Experimental Protocol
Surya T. Madabattula, Joel C. Strautman, Andrew M. Bysice, Julia A. O’Sullivan, Alaura Androschuk, Cory Rosenfelt, Kacy Doucet, Guy Rouleau, Francois Bolduc
University of Alberta, Department of Pediatrics; McGill University, Montreal Neurological Institute and Hospital;
We present an optimized inexpensive and reliable negative geotaxis assay in Drosophila melanogaster as a model for neurodegenerative disorders. Being more sensitive to mild locomotor defects, this assay will help screen for potential genetic interactions and drug targets.
Visit www.jove.com? to explore our entire library of 14,000+ videos of laboratory methods and science concepts.
JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching.
Subscribe to our channel: / jovejournalofvisualize...