Thank you, Dr. Rossi. I've been watching your videos for a few months now. I worked doing medication management for a homeless clinic and a schizophrenia clinic (Clozaril clinic). I started that job fearful of LAIs, and as an NP, I wasn't sure I should use them. I left that job feeling like it was the best thing I'd ever done in a professional sense. The change in the patient's life while using LAIs was profound and it changed the way this old ER nurse felt about schizophrenia and mental health in general. I'm so glad I found your channel.
The analogy that I have heard regarding the progression of deterioration in the schizophrenic patient and the number of psychotic breaks goes something like this: treatment of psychosis is akin to going "to war. The war is won but not all the soldiers return" referring to the psychosis being brought under control but the recovered patient having lost a bit of normal cognitive capacity i.e. judgement, a further decline in both positive and negative symptoms of the disease, insight, etc.
I would say that is fair, treatment has improved some aspects of the disease but other continue to major problems. I would agree the cognitive dysfunction is the symptom that is most concerning on a long term basis
Thank you for this information, my daughter is in a manic episode and we’ve been trying to get her help since Friday, but since she’s not considered a dts/dto, they won’t get involved, so tomorrow her husband is hoping to get her to go see her Dr where he hopes to bring up using injectables, she is currently on vraylar and quetipine . Thank you for you willingness to share your knowledge 🙏🏼
I'm on the zyprexa relprevv injection. My psychiatrist put me on it because I would stop taking my meds due to paranoia about the side effects and end up in the hospital. The main thing I dont like about the injection is I have to wait 3 hrs in the clinic after each injection. I go in every two weeks.
Possibly, as we know there are two FDA approved options for behavioral disturbances associated with ASD aripiprazole and risperidone both come in LAI formulations. If the person has demonstrated benefit and tolerated the medication well but adherence is an issue or the person does not want to take a pill daily then its an option. Hope this helps
Great video! Can you please do another video on paliperidone as my husband has just started receiving this injection due to a drug induced psychosis Thank you
I’m forced to take it too due to a drug induced psychosis and it’s hell. My thoughts are all jumbled and at times I think it’s making me depressed. Hope your husband had better results but this drug generally receives bad reviews
I'm schizoaffective, a treatment-resistant depressive, and have Asperger's. In no way can I 'win' by being sedated against my will to the point where I need harsh stimulants prescribed like Adderall or Modafinil to be able to function. I haven't been able to drop the hundred pounds I gained from Invega/Risperdal/Abilify and now have prediabetes. I want to get off of this shit (and disability) so that I can 'win' objectively.
What is the minimum oral dose a patient needs to be taking in order to be able to switch over to the injectable? For example with Olanzapine, how much oral Olanzapine do you need to be on in order to be able to get an equivalent long acting injectable dose?
For aripiprazole the lowest LAI dose is 10 mg/day, which is one of the reasons I do not use it for depression. The dose is beyond what I would normally prescribe. For olanzapine the lowest dose is 10 mg/day, the LAI can be dosed as 10 mg/day, 15 mg/day, or 20 mg/day depending on the goal. Hope this helps
Brilliant as usual I like to know according to your experience if you see any different regarding rate of response if we give our pt injectable druges and if there is any preferancr in the outcome realy I confused about it because we still on the old fluphenazine injectable and we didint offer any new injectable drugs for our in pt
Very good video! I have USDT in my OKX wallet and I have my recovery phrase. 「pride」-「pole」-「obtain」-「together」-「second」-「when」-「future」-「mask」-「review」-「nature」-「potato」-「bulb」 How do I transfer them to Binance?
hello, I have tourettes and recently tried abilify for it and I my tics seemed to get worse on it. Is that a potential side effect of this medication? I was on 10mg per day. Thanks
My struggle is talking patients into taking the shot in a situation where the patient is taking an oral medication with compliance. In this situation I can’t force an LAI. Usually it’s a patient with a fear of needles or feeling uncomfortable with the idea of having a medication in their body for that long. Any tips on how to overcome this barrier and get patients more comfortable with taking the shot?
I always start the conversation with my personal experience taking medication. It's hard to remember and life gets in the way. I will place a strong emphasis on the positive aspects of being on the medication decreased mortality, decreased relapses, and normalize the needle part the same way I would discuss getting the COVID vaccine for example. You can never force someone to take the medication, even in the inpatient setting you can't force it, so you work to build insight into the ways it can enhance their life. Hope this helps
![Long-acting injectable antipsychotics [Depot Antipsychotics] Injectable Antipsychotics](/img/n.gif)
Thank you, Dr. Rossi. I've been watching your videos for a few months now. I worked doing medication management for a homeless clinic and a schizophrenia clinic (Clozaril clinic). I started that job fearful of LAIs, and as an NP, I wasn't sure I should use them. I left that job feeling like it was the best thing I'd ever done in a professional sense. The change in the patient's life while using LAIs was profound and it changed the way this old ER nurse felt about schizophrenia and mental health in general.
I'm so glad I found your channel.
Thank you so much for all the love and support, I'm always happy to help
The analogy that I have heard regarding the progression of deterioration in the schizophrenic patient and the number of psychotic breaks goes something like this: treatment of psychosis is akin to going "to war. The war is won but not all the soldiers return" referring to the psychosis being brought under control but the recovered patient having lost a bit of normal cognitive capacity i.e. judgement, a further decline in both positive and negative symptoms of the disease, insight, etc.
I would say that is fair, treatment has improved some aspects of the disease but other continue to major problems. I would agree the cognitive dysfunction is the symptom that is most concerning on a long term basis
Oh yeah in league of legends in dosing and proper timeliness if medicines it as an existentialism about just eat in parallel with schizophrenia itself
Why is a LAI version of clozapine not available? Even 30 days in case of side effects?
Thank you for this information, my daughter is in a manic episode and we’ve been trying to get her help since Friday, but since she’s not considered a dts/dto, they won’t get involved, so tomorrow her husband is hoping to get her to go see her Dr where he hopes to bring up using injectables, she is currently on vraylar and quetipine . Thank you for you willingness to share your knowledge 🙏🏼
No problem, LAIs have a lot of benefits in serious mental illness, and I always consider them if the patient is appropriate
I'm on the zyprexa relprevv injection. My psychiatrist put me on it because I would stop taking my meds due to paranoia about the side effects and end up in the hospital. The main thing I dont like about the injection is I have to wait 3 hrs in the clinic after each injection. I go in every two weeks.
Great video is always, thank you so much for your hard work on this! Would you ever consider using aristada for agitation in autism?
Possibly, as we know there are two FDA approved options for behavioral disturbances associated with ASD aripiprazole and risperidone both come in LAI formulations. If the person has demonstrated benefit and tolerated the medication well but adherence is an issue or the person does not want to take a pill daily then its an option. Hope this helps
Great video!
Can you please do another video on paliperidone as my husband has just started receiving this injection due to a drug induced psychosis
Thank you
I’m forced to take it too due to a drug induced psychosis and it’s hell. My thoughts are all jumbled and at times I think it’s making me depressed. Hope your husband had better results but this drug generally receives bad reviews
I'm schizoaffective, a treatment-resistant depressive, and have Asperger's. In no way can I 'win' by being sedated against my will to the point where I need harsh stimulants prescribed like Adderall or Modafinil to be able to function. I haven't been able to drop the hundred pounds I gained from Invega/Risperdal/Abilify and now have prediabetes. I want to get off of this shit (and disability) so that I can 'win' objectively.
Thank you for letting me know what to expect. I go for my first injection next week and the second a week after.
What is the minimum oral dose a patient needs to be taking in order to be able to switch over to the injectable? For example with Olanzapine, how much oral Olanzapine do you need to be on in order to be able to get an equivalent long acting injectable dose?
For aripiprazole the lowest LAI dose is 10 mg/day, which is one of the reasons I do not use it for depression. The dose is beyond what I would normally prescribe. For olanzapine the lowest dose is 10 mg/day, the LAI can be dosed as 10 mg/day, 15 mg/day, or 20 mg/day depending on the goal. Hope this helps
Can you please do a video on why anxiety makes you vomit? And any medication or tips to stop it?
Brilliant as usual I like to know according to your experience if you see any different regarding rate of response if we give our pt injectable druges and if there is any preferancr in the outcome realy I confused about it because we still on the old fluphenazine injectable and we didint offer any new injectable drugs for our in pt
Very good video! I have USDT in my OKX wallet and I have my recovery phrase. 「pride」-「pole」-「obtain」-「together」-「second」-「when」-「future」-「mask」-「review」-「nature」-「potato」-「bulb」 How do I transfer them to Binance?
Great content!
hello, I have tourettes and recently tried abilify for it and I my tics seemed to get worse on it. Is that a potential side effect of this medication? I was on 10mg per day. Thanks
Its great as its helpful
As antipsychotics are
Unpleasant to take
And going home on a oral
Form is tempting to stop
Thank you
Thank you .…mother of a 46 yo son with schizophrenia.
My struggle is talking patients into taking the shot in a situation where the patient is taking an oral medication with compliance. In this situation I can’t force an LAI. Usually it’s a patient with a fear of needles or feeling uncomfortable with the idea of having a medication in their body for that long. Any tips on how to overcome this barrier and get patients more comfortable with taking the shot?
I always start the conversation with my personal experience taking medication. It's hard to remember and life gets in the way. I will place a strong emphasis on the positive aspects of being on the medication decreased mortality, decreased relapses, and normalize the needle part the same way I would discuss getting the COVID vaccine for example. You can never force someone to take the medication, even in the inpatient setting you can't force it, so you work to build insight into the ways it can enhance their life. Hope this helps
cant ejac on invega
I've had the same problem. I'm wondering if anything can be done...
@@chrishamilton5181 find a way to stop taking it
you should give this shot, maximun dose, to donald trump
What a dumb thing to say
@@katrinaisalwayscorrect you should recive this shot too, maximum dose
@enriquemartinez7453 anyone who doesn't think like you huh? You sund healthy
@@katrinaisalwayscorrect you really need it because you health is in my best interest. and is for your own good
Este comentario didn't age well
What a sick joke
I got schizophrenia