Pamela Ohashi - Immunoregulation and the tumor microenvironment

Although PD-1 blockade has transformed cancer treatment, a deeper understanding of tumor immunobiology and inhibitory mechanisms are needed to take immunotherapy to the next level. This webinar will cover topics including the cell types that express key B7 family members and their receptors including PD-L1, B7-H3, B7-H4 and PD-1 and discuss whether these findings align with the traditional views for what is going on in the tumor microenvironment. In addition, it will cover unexpected immunoregulatory mechanisms that we have found focussing on innate lymphoid cells.