Thankyou mr victor for coming to my rescue! Your study materials and videos have helped me tremendously. Organic chemistry used to be a pretty daunting subject for me but now, thanks to you, i am able to comprehend even the more complex topic in OC. Thankyou in abundance❤
i've just found your channel and website and honestly i'm amazed, i wish i had found it years earlier! currently im studying for my ochem exam (and i'm taking this course for the third time...) and i'm really hopeful this time. thank you for your work!
Hey thank you for the video:) Great explanation! Could you explain the Michel Addition? I didn't understand the principle of soft and hard nucleophiles...
Sir Love Frm India 😁 well i dont really like cemistry but ur vdos r really gud to revise concept in free time with fun 😁 nd may be u dont even noticed that u have completed whole class 12th syllabus of organic except a topic Phenols 😂😂 so tqq sir
Btw I m no one to say that but sir try to upload the solution of organic section of upcoming JEE advanced exam maybe it will accumulate indian students 😁 coz many teachershere uploads wrong solution of advanced and later correct it 🫡❤organic portion roughly have 15 to 20 questions
Thank you for your feedback and your kind words! My focus right now is a typical US curriculum. Once I get done with that, I'll start branching into other topics and curricula.
Hello, i really like videos they are so helpful and clear 👍 please can you make exercise for tautomerism like you made for newman prjection that was so helpful for me
Thank you! I'm taking a bit of a break from UA-cam for the moment to catch up with a few other projects I have going on, but I do have a "practice questions" video for this topic on my to-do list for the future.
Could I ask about why cyclic 1,3 dicarbonyl beta keto esters are usually seen in their enol tautomeric form and what influence does “cyclisation” have on this tautomeric equilibrium? Also regarding your previous video on Thermo/kinetic enolates, I’m unsure how the choice of base works e.g LiHMDS or NaHMDS and whether they are more likely to yield the kinetic/thermodynamic enolate, as well as vinylogous deprotonation of enone like species in preference of alpha deprotonation
It's a loaded question lol The first one is rooted in the conformation and orbital interactions that you would have in a cycle (typically a 6-membered ring) as opposed to the open-chain molecule. While you don't have intramolecular hydrogen bonding, it's easier to enolize the cycle than an open chain molecule due to the soft conformational lock you see in a cycle that virtually has the perfect conformation for the required orbital overlaps. The second part, I'm not quite sure what exactly you're asking about. Both Li and NaHMDS can be used to make kinetic or thermodynamic enolates depending on how you do the reaction. The difference here is that Li will coordinate with O easily forcing the formation of the E-anolate, while Na doesn't do it as much. This is also mostly applicable to the kinetic enolates, once you're in thermodynamic conditions, the chelation effects for enolates are much less prevalent. I'll make a video on that at some point, but for now, I'm focusing on the typical undergrad curriculum and this would be a more advanced topic.
@@VictortheOrganicChemistryTutor omg tysm For the second question, i phrased it poorly, I think I meant what effect does the counter ion have on thermo/kinetic enol ratio formed, and what conditions are often used to deprotonate the gamma positions of say for example, an enone’s alpha position to form a regular enolate, or the gamma position to form the vinylogous enolate, preferably trapped by silyl groups etc.
@@UniCorneliusfan21 Oh yea, that a topic is a way more involved conversation than what comments under the video would allow for. As I've mentioned, I'm 3/4 done with the sophomore topics, and once I am, I'll start making videos on more advanced material. I should be recording more advanced topics starting around next fall. And I'll be definitely talking more about enolates, Zimmerman-Traxler and Felkin-Ahn models (all variations), and more fun advanced organic chemistry stuff.
@@VictortheOrganicChemistryTutor ok thanks, can’t wait! Seriously I can’t find too many sources for advanced o chem so my foundation is really shaky past that, I have so much trouble dealing with stereoselectivity and i can’t really get my head around it that well so yeah
Thankyou mr victor for coming to my rescue! Your study materials and videos have helped me tremendously. Organic chemistry used to be a pretty daunting subject for me but now, thanks to you, i am able to comprehend even the more complex topic in OC. Thankyou in abundance❤
You are very welcome
i've just found your channel and website and honestly i'm amazed, i wish i had found it years earlier! currently im studying for my ochem exam (and i'm taking this course for the third time...) and i'm really hopeful this time. thank you for your work!
Welcome aboard!
Hey thank you for the video:)
Great explanation!
Could you explain the Michel Addition? I didn't understand the principle of soft and hard nucleophiles...
Great question i have issues with the exact same Topic a video about it would be highly appreciated ☺
I’ve been pretty busy this summer with other stuff, but those tutorials are definitely on my todo list.
Thank you ❤
You're welcome 😊
Thank you 🫡
Hello, I find your videos very helpful thank you so much for your effort 😊 Could you please do a video on Knoevenagel Reaction as well ?
It is on my to-do list for this summer.
Sir Love Frm India 😁 well i dont really like cemistry but ur vdos r really gud to revise concept in free time with fun 😁 nd may be u dont even noticed that u have completed whole class 12th syllabus of organic except a topic Phenols 😂😂 so tqq sir
Btw I m no one to say that but sir try to upload the solution of organic section of upcoming JEE advanced exam maybe it will accumulate indian students 😁 coz many teachershere uploads wrong solution of advanced and later correct it 🫡❤organic portion roughly have 15 to 20 questions
Thank you for your feedback and your kind words! My focus right now is a typical US curriculum. Once I get done with that, I'll start branching into other topics and curricula.
Hello, i really like videos they are so helpful and clear 👍 please can you make exercise for tautomerism like you made for newman prjection that was so helpful for me
Thank you! I'm taking a bit of a break from UA-cam for the moment to catch up with a few other projects I have going on, but I do have a "practice questions" video for this topic on my to-do list for the future.
Will there be retrosynthetic analysis on your channel ?
Eventually, yes.
Could I ask about why cyclic 1,3 dicarbonyl beta keto esters are usually seen in their enol tautomeric form and what influence does “cyclisation” have on this tautomeric equilibrium?
Also regarding your previous video on Thermo/kinetic enolates, I’m unsure how the choice of base works e.g LiHMDS or NaHMDS and whether they are more likely to yield the kinetic/thermodynamic enolate, as well as vinylogous deprotonation of enone like species in preference of alpha deprotonation
It's a loaded question lol
The first one is rooted in the conformation and orbital interactions that you would have in a cycle (typically a 6-membered ring) as opposed to the open-chain molecule. While you don't have intramolecular hydrogen bonding, it's easier to enolize the cycle than an open chain molecule due to the soft conformational lock you see in a cycle that virtually has the perfect conformation for the required orbital overlaps.
The second part, I'm not quite sure what exactly you're asking about. Both Li and NaHMDS can be used to make kinetic or thermodynamic enolates depending on how you do the reaction. The difference here is that Li will coordinate with O easily forcing the formation of the E-anolate, while Na doesn't do it as much. This is also mostly applicable to the kinetic enolates, once you're in thermodynamic conditions, the chelation effects for enolates are much less prevalent. I'll make a video on that at some point, but for now, I'm focusing on the typical undergrad curriculum and this would be a more advanced topic.
@@VictortheOrganicChemistryTutor omg tysm
For the second question, i phrased it poorly, I think I meant what effect does the counter ion have on thermo/kinetic enol ratio formed, and what conditions are often used to deprotonate the gamma positions of say for example, an enone’s alpha position to form a regular enolate, or the gamma position to form the vinylogous enolate, preferably trapped by silyl groups etc.
@@UniCorneliusfan21 Oh yea, that a topic is a way more involved conversation than what comments under the video would allow for. As I've mentioned, I'm 3/4 done with the sophomore topics, and once I am, I'll start making videos on more advanced material. I should be recording more advanced topics starting around next fall. And I'll be definitely talking more about enolates, Zimmerman-Traxler and Felkin-Ahn models (all variations), and more fun advanced organic chemistry stuff.
@@VictortheOrganicChemistryTutor ok thanks, can’t wait!
Seriously I can’t find too many sources for advanced o chem so my foundation is really shaky past that, I have so much trouble dealing with stereoselectivity and i can’t really get my head around it that well so yeah
pls is this organic chemistry for universities or senior high school (secondary school in Nigeria) because i don't quite understand it
My channel is geared towards college level chemistry.
Nice ❤
Thanks 🔥
Sir I can provide u jee advance organic question may be 10 to 15 wanna upload it love from india ❤🎉
Виктор?! Лол😂