This clip is pulled from the "Dr. Andy Galpin: Maximize Recovery to Achieve Fitness & Performance Goals" episode of Huberman Lab. The full episode can be found on UA-cam here: ua-cam.com/video/juD99_sPWGU/v-deo.html
Let’s get real. There’s some good info here (perception being one item) but some misses as well (it’s most likely trauma and doesn’t always take 24-48 hours TO PERCEIVE, the inflammatory process is immediate). Here’s the real answers: The root of DOMS is due to “excessive” (insufficient adaptation) to eccentric loading that can cause micro trauma due to structural damage (membrane, myofibrillar) and the activation of proteases, prostaglandins, and histamine production which follow. This may not manifest as the perception of soreness (pain) for a few hours. DOES NOT REQUIRE 24-48 hours to perceive! Ever workout in the evening and wake up sore? The problem these guys are having is thinking this process STARTS between 24-48 hours, when we are talking about pain perception. However, again DOMS can be perceived (soreness) within only a few hours!!! The miss here is not connecting that DOMS may not resolve for a couple days and that is highly dependent on what’s called the “repeated bout effect”, essentially neural and muscular adaptations that minimize damage/promote recovery. By the way, I’m a also a Kinesiology professor and have been teaching Exercise physiology for over 12 years.
@wethomas3 i exercise in the afternoon/evening and don't wake up sore. The soreness usually starts somewhere between lunch and evening the next day. If i do high volume low intensity it starts sooner, if i do high intensity low volume it takes much longer.
@@MrHaggyy it depends. Resistance trained individuals also have a much higher resistance to DOMS. If you did an entirely different movement and/or changed the tempo you might experience DOMS (the perception of soreness). It goes without saying, if you are untrained, then the response will be greater.
Lemme try to summarize: 2:50 traditional dogma - muscle micro tears (probably NOT the main cause) 3:57 delayed inflammatory immune response 4:56 fluid accumulation which triggers nociceptors (pressure sensors) 5:43 neural feedback loop (mixing of different nerve signals from and into muscle fibers) 9:55 pressure sensors triggered by stretched muscles interpreted as pain in the brain rather than pressure in the muscle spindles 10:35 low level movement better to relieve muscle pains (anti-stretch, drains fluid) 12:07 free radicals from muscle metabolism (he's not too sure, still a theory, may be the trigger for all these) 13:44 damage to cell walls which promotes free radical leakage usually due to high intensity muscle work rather than cardio/low intensity (which may actually help in recovery, see 10:35) Hth.
The answer to the question was: scientifically we don’t know but my best guess is it’s probably just a neurological feedback loop signaled by pressure censors in the muscles from them swelling from the exercise.
nah, don't play it off as a joke that i'm ruining. a lot of people here are incapable of listening for 14 minutes (hell, he even mentions the most important part at ~5 minutes) and proceed to blame Dr. Galpin for mentioning other relevant, interesting information.@@arkadaurum298
@@spontaneousbootay 100% it did. So much fluff and showboating without actually answering anything. These guys should be in politics. Can you summarise it?
@@lorenzomuhammad1715 they just explained how the motor neurons and muscle fiber spindles work. The soreness is like edema. You need to move the waste product out by massaging and moving the muscles in different ways.
@@lorenzomuhammad1715they didn’t answer anything because there isn’t a clear consensus on the subject yet; it’s an area of ongoing scientific investigation.
I worked in exercise physiology, and consulted on research for 30 years. My opinion has been for about a decade that muscle soreness is the result of lymphatic vessels stretching as lymphatic waste is worked out of a muscle in the immune response to resistance training. Muscle get sore relative to the amount of lymphatic vessels that drain them, and things that promote lymphatic drainage reduce soreness. It also suggests the use of light workouts/sled work between workouts to accelerate the recovery and why complete inactivity in days after training slows down recovery.
@@zachdancy5828 No. Ice and NSAIDs actually block the normal lymphatic drainage and slow things down. NSAIDs by the way also block prostaglandin which is important for the hypertrophy response. Hot water, heat, massage, light calisthenics. Training 6 days a week though you are probably in effect using workouts to help restore muscles you worked in earlier days. So if you do a chest workout one day, and then train your back 1-2 days later with some pulldowns or pullovers you are probably helping to restore your chest. If you only do your legs once a week though, you might want to do something restorative for the legs 2-3 days later like pushing and pulling a light sled.
Interesting. What "lymphatic waste" is in our muscles? Why is it there? Is it good to drain it? Is resistance exercise the best way? I'm dealing with serious doms right now.
This discussion is absolutely fascinating. We are so lucky to live in a time where we understand so much about the body that we can have these conversations.
Ok they started saying that muscle tears/damage is not why you get soreness then they end by saying the exact opposite, that a loaded tension on the muscle damages the muscle cell wall to cause soreness. First off all it’s a contradiction and secondly we don’t have cell walls, only cell membranes.
Personally I think a lot of this comes down to how we define "Soreness". So.. I had a Fusion about a decade ago now, and sometimes when it Aches I might say to someone "Bah my back is Sore" then give it a rest for a minute. However this is not the same sensation as say if I went to the gym and did a bunch of Bicep Exercises then the next morning felt the "Soreness" in my Bicep. While both sensations could be described as "Soreness" they are not the same. So I think a lot of that boils down to our descriptor of the Sensation and a individuals perception of their body and how they articulate that to others. Chances are if your Muscle Belie feels sore, you tore Muscle Fibers. If it's extremely sore your tore them badly. If you can barely move the muscle without sharp pain, you probably made a significant tear that will leave scar tissue.
Next question, is soreness optimal for growth/strength, or is active recovery to get that fluid/inflammatory response out of the muscle better? Better meaning leading to optimal growth/strength.
Dr. Mike Iseratel from renisance periodization covers this somewhat. Basically you need to let yourself get inflamed/sore in that first 24 hr period to get good gains but after that unsore yourself
Same here. I was just looking for a UA-cam video about how good it feels to agree with me. Not sure why so many people think of it as pain and not enjoyable.
When he said stretching is the opposite thing you should do to reduce soreness and using low grade movement I immediately thought of Westside Barbell and their use for years of doing sled work for recovery. Because it’s only a contraction and no loaded eccentric movement involved it seems like the perfect solution. Do sled presses, rows, loaded dragging, sled fly and reverse fly movements.
Thats really interesting if you compare endurance vs strength soreness. The most pain i know is when switching between both extremes. For example heavy squads and jogging. From your explanation and my perception there are multiple sources for "soreness". When i go running the soreness kicks in quite immediatly after i'm 2h into it or after the start when the run is shorter. I would say thats an immediate response to wear caused by all those steps. Strength training kicks in 24h delayed. Makes sense that it's linked to buildup and recovery processes and getting rid of liquid, mostly water, that is a byproduct of almost any organic chemistry. I think soreness despite it's linkage to pain is a perceptional mechanism of our body to prevent injury. It prevents you from doing excessive exercises while the muscle is still recovering and favors light exercise that is primarly circulating liquids, not working the muscles. Would love to hear your thoughts on that.
idk, I've had running soreness that came immediately, came 2-3 days later, and came the next day. I've also had strength stuff that showed up immediately, showed up 2-4 days later, and the next day. the only thing I've noticed between the two (I run marathons and I lift weights) is that I can have a hard strength workout stay with me for as much as a week, whereas the worst soreness I've had from a run has only lasted 4 days at the most. I can't even really hazard a guess as to why this is because I'm not a scientist or a doctor.
@@janemf I haven`t done a marathon jet but soreness kicking in 2 days + delayed is something i have never heard of. Only idea i have right now is that you hit muscles that are still recovering from an intense strength session with an intense endurance session or the other way around. That way you get closer and closer to a propper injury in the muscle that holds for much longer.
@@MrHaggyywhen I was doing CrossFit 10-11 years ago, it was very common for everything to feel fine and then suddenly 3 days later (if I stopped working out) horrendous soreness would set in. it always seemed to be 2-3d out so my goal was to never take more than 1 day off.
Very curious about Dr. Galpin mentioning free radicals being released from mitochondria. “Free radicals,” have bit somewhat of a buzz word the past few years, with emphasis being placed on trying to increase our antioxidants to minimize free radicals. Im curious if anyone knows whether this free radical release from exercise that Dr. Galpin refers to is healthy, unhealthy or neutral.
"radicals" are positive ions... their "free" when is just the ions floating around; calcium , selenium, magnesium 2+ ion charges...+ ion charges in the body are "acidic" = lowers pH.... most people are normally low pH = acidic....for complex reasons , normal goal pH = 7.36......most people are at 7.25 to 7.35 pH, acidic....eat more baking soda until your urine on test strips shifts up to around 6.7pH, urine is usually low around 5 - 6.5 pH
Anti Oxidants could possibly blunt the response from exercise. I am not the best one to explain this, but I believe it. Same for cold plunges too soon after exercise.
There are some aspects of this explanation that make a lot of sense, but then like all things it should be testable. If it is truly immune inflammation putting internal pressure on spindle cells, then some experiments could be validating. You should be able to measure that pressure with more pressure equal to more DOMs; visible resting tension and swelling in the muscle should also equate to more DOMs. Likewise you should experience less DOMs the lower the measured pressure. A muscle fully at rest but in a position it would be if fully contracted, completely slack, should feel less pain or no DOMs as pressure should be relieved.
This is always what I tell my clients when they are sore and it works for them really well. Just lighter versions of the exercises. Or a walk etc. To reduce soreness. Then I tend to look at other behavioral patterns that could be contributing. Sleep,stress management, caloric intake, etc.
Microscopic morphologic studies are easy enough to do on the skeletal muscle. In an appropriately applied exercise program/movement no damage to the functional unit of the muscle has been found. Scarring is the bodies normal response to muscle tissue damage not improved function with hypertrophy. If tearing or damage were the etiology of muscle damage from correct exercise the result would be crippling. It is not, it is in fact the opposite.
@@georgia9406 Clearly, you have the ability to read my comment. To comprehend it and follow up with a logical question. Therefore, you are serious. I am close to saying that. There is no evidence on a microscopic level that indicates a disruption of the functional unit involved in muscle contraction. On any comprehensive and or reliably predictable model is this shown. Moreover, soft tissue does not heal from trauma in the manner that is congruent with any DOMS theory. In a nutshell, In most all cases muscle tears are not occurring at all in post exercise soreness. This discussion has been ongoing for over 35 years and still no one offers a solid answer. The discussion today is precisely that of 1982 and has not changed.
"Free Radicals are waste products...just like smoke from your vehicle exhaust...... Free Radicals causes this inflammation".......in my opinion... Earlier this was thought be due to the lactic acid,produced from anaerobic pathways.
Look up electron transport chain, basically when breaking down carbon there is several stages, first is glycolysis, then pyruvaye oxidation the the kreb cycle then electron transport chain. That is the end result of carbon metabolism
If the inflammation and pain initiates muscle repair/growth, then why would you wanna take the fluid out of that muscle to alleviate pain ? Shouldn't you be letting the repair process run its course naturally instead of rushing things ? i.e rest and let the process occur rather than doing low intensity cardio.
no, there is lots of waste fluid inside a muscle, weak exercise contract the muscle so the waste fluid gets pushed into the lymphatic system, then to kidneys , you recover faster
Another thing you want is a lot of acid build up from electron transport chain and glycolysis so you want to add oxygen to these to remove them from the muscle
I may be an outlier, but I am well trained with 7 consistent years in the gym. I have trained all frequencies and volumes but largely stuck 2ity low volume, low frequency due to soreness. I am sore 4-5 days post workout. I am 56 now but this was also true in my 20s.
i am 57 and just started getting sore all the time about a month ago. low volume heave and light day, about 4-5 days apart, i am sore same day as i lifted this time.
This is a clip from a much longer episode where he breaks down and explains a lot of the terms he's using. Even still I think there's so much nuance and specificity here that breaking things down into layman's terms would actually be detrimental to understanding the topic, especially for those on the other end who want the specificity
I'm curious how diet plays a role in muscle soreness. I cut out sugar, vegetables and grains 5 months ago and no longer get sore the following day like I use to.
It could just be that your body adapted at the exact time you quit these foods by coincidence. May just be a timely coincidence, but I’m no professional.
Exactly, I can do a workout and have carbs in my system and be sore AF I go carnivore and get the carbs out of my system do the same workout and not feel shit
I noticed no muscle soreness afyer as workout when fasting. I have done some pretty hard workouts too. Nice to know others have experienced the same thing.
@overlordfemto7523 I am in my 40's and have been training since a teenager. I also have my Masters in Kinesiology so I know how to train and I know how the body works. I just don't know why I don't get sore like I use to since changing my diet. Has to be something with the diet.
I'm dealing with getting out of bed frequently to pee. I usually wait train after work around 4 pm, then dinner. I try to stop drinking fluids around 6:30 pm, but some night, I'm up five times to pee. It's very frustrating. I suspect I may not be getting enough fluid during the morning and early afternoon.
Love it “ cell wall” when your describing animal cells . Hope that was a slip. However, joking apart some interesting points. What also MUST be considered is mechanical effects of cellular oedema on tendoni sensory fibres as this is where DOMS is mainly felt near muscle insertion points. Also why we get a lower immune response / reduced pain sensation as training progression ( time training/ years) continues.
Ok so main takeaway delayed soreness 24-48 hours is not related to muscle tears. If it happens right after workout or during probably is muscle tears. Which is a different soreness so muscle tears soreness vs doms ?? So do with that what you can idk
I experiment with keto diet, on and off for about a month very strictly, and when on keto diet I never experience muscle soreness, and when having carbs in a diet, I experience soreness almost every time, I train with heavy weight 2-3 times per week each body part.
Iyengar yoga (and trigger point self massage) was one key to healing my deadline driven job related muscle soreness brought on by bracing, involuntary breath holding, and sitting for long hours to make my deadlines. Total game changer
@@nancycm I can't do yoga for religious reasons but I do employee dynamic stretching and it helps. Recently I took a long soak in Epsom salts and baking soda and it helped a lot. I'm likely magnesium deficient and I battle autoimmune issues.
This is actually just a game of medical ‘taboo’ (the game where you describe something without using key words). The key words they aren’t allowed here are Lactic acid. Fascia
Lactic acid is very obvious and if you listen to the full episode then you’ll hear him talk about that but lactic acid is not a problem when preforming aerobic training or if you training to run through kreb cycle, because lactic acid gets broken down during that process. So he is not talking about anaerobic training specifically
TBH: I think much of what purports to be new “science” is little more than elaboration of narrative twist, beyond any point of establishing causation or providing any utility. The way in which the subject gets talked about (in this case muscle soreness) implies new meaningful discoveries. You can always have a new “understanding” of something without ever establishing a new provable thesis with consequential effects.
I'm not sure where you are coming up with that. with as little as 10g/day you can easily gain 10lbs of weight that is presumed to be mostly intramuscular water volume. Way more than what you presumably get by inflammation after lifting. One does not see much weight gain after a lifting session.@@lunam7249
natural process of "aging" and your fitter now....olympic athelete have notoriously slow DOMS 48- 80 hours later!!! this also rewards olympic atheletes to train more often and harder.....wheas people with 1 hour later DOMS are sedintary mo exercise people!!! great question!❤
Lactic acid build up is the main cause of muscle soreness diet and stretching and warming down can help reduce soreness but any kind of exercise can cause it especially when starting out of conditioning👍🏽
Hey Dr. Huberman, I agree with Dr Galpin on muscle soreness. I have found in my practice I teach my clientys how to allevaite soreness in minutes. IN using my technique, I see people every day that are in pain from muscles soreness when I gently touch them and within in minutes, I can press as hard as I want and the pain is gone. My technique includes self-massage, special type of stretching, not static or dynamic, and how the brain works with the tension in the muscle. I realize there is not a lot of studies in this area and nothing to prove what I do, but I am telling you, my clients 55 and above, are amazed at how quick the muscle soreness stops. I think it is worth studying. WOuld love to speak with in more detail.
When you go carnivore, you don't get sore. Work on the same muscle group for hours and hours but never get sore. Much more research is needed considering this fact. It's fascinating how many things that happen to us including disease are all metabolic, including soreness.
The complicated, evasive approach to answering the questions shows how little understanding this “expert” has. Politicians answer definitive questions by evading and redirecting.
You know he is not simply answering 1+1, this is a very complex process that has a lot of factors that need serious consideration. What answer did you expect here?
These guys are reaching. It’s trauma, whatever you want to call it. The pain/soreness can onset within HOURS. For example, workout in the evening, the next morning you’re sore. Also activity (blood flow) can mitigate the pain/soreness (perception), so for example if you workout in the morning and you’re active afterwards you may delay the soreness/pain which is again PERCEPTION based. It doesn’t take 24-48 hours for the physiological part to START! The problem is that the soreness generally doesn’t RESOLVE in that time (24/48 hours).
@@lunam7249 let explain perception to you. Perception is highly subjective. That does not mean perception doesn’t have a physical trigger/stimulus. For example, a common perception scale we use in our exercise physiology lab is rate of perceived exertion (RPE). Does RPE have a relationship with physiological alterations? Sure it does cardiovascular strain, muscular strain, thermal strain, etc play a role, but can RPE be different if these strain variables are controlled? Absolutely. Let me further explain to you. Have you heard of an epidural, a “saddle block”? That blocks pain signaling to the brain. Does that mean that biochemical processes of pain are prevented at their root? The answer is NO. So, pain is very much perceptual. It relies totally on sensory triggers/afferent impulses to the brain. Block those pathways off and no pain, even though someone’s leg may be cut off. Have a nice day.
@@Bimmer_Bill i understand what perception is.....obviously , give everyone IV fentanyl and voila "no pain" perception.....however, im discussing "medical doctors" who wont even perscribe opioids for a broken ARM!!! alot of doctors are TERRIFIED of the FDA or FBI " claiming they "over-prescribe"!! so these scardy-cat doctors run around just telling every broken arm patient the "pain , is just all in your head"....gives the patient tylenol as kick them out of the E.R.....
🎯 Key Takeaways for quick navigation: 00:30 🤔 ¿Qué refleja realmente la sensación de dolor muscular? No se limita solo a los músculos, involucra otros sistemas y tejidos. 02:55 🚫 El dolor muscular no es principalmente causado por "microdesgarros" en los músculos, como se creía. La inflamación y la respuesta inmunológica son factores clave. 05:46 🤯 El dolor muscular puede ser resultado de un bucle neural, no necesariamente de daño muscular. La presión sobre los receptores nerviosos de los husos musculares podría ser la causa. 11:28 🏋️ Realizar ejercicios de baja intensidad después de un entrenamiento intenso puede ayudar a aliviar el dolor muscular más rápido que descansar por completo. 13:22 🔍 Se postula que la liberación de radicales libres de las mitocondrias puede desencadenar una respuesta inflamatoria en los músculos y contribuir al dolor muscular. Más investigación es necesaria para confirmar esto. Made with HARPA AI
Everybody is trying to reinvent the wheel. The reason why it's delayed is your body's natural pain killers wear off. When the endorphins wear off within 24 hours you will start feeling the pain from the micro tears. It's not some weird psychological feedback loop! Geez people come on!
That ‘weird psychological feedback loop’ is pretty well proven to just be how your brain and nervous system works. I’m not sure endorphins have ever been proven to ‘block pain’ what books have you been reading
Interesting, I recently heard on Dr. Anthony Chaffee's you tube channel that we feel less to no more muscle soreness after an intense workout because we are no longer experiencing the inflammatory factors in plants. I certainly have felt this happen in my own body once I started on a zero carb no plant diet. I have a physically demanding job and my elbow and knee pain are practically non-existent now.
@@deadbones23 if the question is why does carbs make muscles sore, one reason is chronically elevated insulin leads to inflammation in the body. Every time we eat, insulin is released. Eating 3 meals plus snacks in between, means insulin is always high. The carnivore diet usually consists of two meals a day of fatty beef. The protein and fat makes us full, so we are able to go 16 hours without eating easily. The insulin drops low during fasting hours, causing fat stores in the body to be released and people lose weight fast.
That makes a lot of sense! My take away from this is do your leg day or whatever then have low intensity muscle movement of that same muscle group maybe throughout the same day and following as well, drink extra water to help this "pumping out of muscle", and take liposomal vitamin C to increase your macrophage activity(which can be seen on microscopes reaching out and grabbing toxins and pathogens...acting like a cleanup crew more of less. Testing this tomorrow. Good information, thanks.
Very interesting. I had no idea liposomal vitamin c even existed. Quick search shows that it enhances absorption and bioavailability. Think I might start taking it 🤓
I don't think there pain receptors anywhere in our body. How would 'they' know what 'pain' is. We do however have a fantastically complex nociception apparatus which will light up when a specific (or non specific in the case of chronic pain) receptor is stimulated enough. That threshold will vary on our level of fatigue; nervous system sensitization, past experiences, etc... What do you think ?
This clip is pulled from the "Dr. Andy Galpin: Maximize Recovery to Achieve Fitness & Performance Goals" episode of Huberman Lab. The full episode can be found on UA-cam here: ua-cam.com/video/juD99_sPWGU/v-deo.html
Thank you so much 🙏🏻
Let’s get real. There’s some good info here (perception being one item) but some misses as well (it’s most likely trauma and doesn’t always take 24-48 hours TO PERCEIVE, the inflammatory process is immediate). Here’s the real answers:
The root of DOMS is due to “excessive” (insufficient adaptation) to eccentric loading that can cause micro trauma due to structural damage (membrane, myofibrillar) and the activation of proteases, prostaglandins, and histamine production which follow. This may not manifest as the perception of soreness (pain) for a few hours. DOES NOT REQUIRE 24-48 hours to perceive! Ever workout in the evening and wake up sore? The problem these guys are having is thinking this process STARTS between 24-48 hours, when we are talking about pain perception. However, again DOMS can be perceived (soreness) within only a few hours!!! The miss here is not connecting that DOMS may not resolve for a couple days and that is highly dependent on what’s called the “repeated bout effect”, essentially neural and muscular adaptations that minimize damage/promote recovery. By the way, I’m a also a Kinesiology professor and have been teaching Exercise physiology for over 12 years.
@wethomas3 i exercise in the afternoon/evening and don't wake up sore. The soreness usually starts somewhere between lunch and evening the next day.
If i do high volume low intensity it starts sooner, if i do high intensity low volume it takes much longer.
@@MrHaggyy it depends. Resistance trained individuals also have a much higher resistance to DOMS. If you did an entirely different movement and/or changed the tempo you might experience DOMS (the perception of soreness). It goes without saying, if you are untrained, then the response will be greater.
Lemme try to summarize:
2:50 traditional dogma - muscle micro tears (probably NOT the main cause)
3:57 delayed inflammatory immune response
4:56 fluid accumulation which triggers nociceptors (pressure sensors)
5:43 neural feedback loop (mixing of different nerve signals from and into muscle fibers)
9:55 pressure sensors triggered by stretched muscles interpreted as pain in the brain rather than pressure in the muscle spindles
10:35 low level movement better to relieve muscle pains (anti-stretch, drains fluid)
12:07 free radicals from muscle metabolism (he's not too sure, still a theory, may be the trigger for all these)
13:44 damage to cell walls which promotes free radical leakage usually due to high intensity muscle work rather than cardio/low intensity (which may actually help in recovery, see 10:35)
Hth.
MVP 👍🏻
Thank you 👊
Wonderful, appreciate this.
Thank you!
pretty good summary
I'm now more clueless about muscle soreness
It’s from pressure due to fluid accumulation in the belly of the muscle 💪
It’s ok… scientists are still clueless about it too 🤣
@@DroomSpook Wrong.
@@MichaelHorstmann Wrong.
@@shark3385 Not clueless.
The answer to the question was: scientifically we don’t know but my best guess is it’s probably just a neurological feedback loop signaled by pressure censors in the muscles from them swelling from the exercise.
Thanks, jesus...I'm watching like just spit it out!
@@Marcow321 he said that part literally in the first part of the video. sorry you're too stoopid to understand
Thank you!
@@beepboop212you’re real fun at parties :)
nah, don't play it off as a joke that i'm ruining. a lot of people here are incapable of listening for 14 minutes (hell, he even mentions the most important part at ~5 minutes) and proceed to blame Dr. Galpin for mentioning other relevant, interesting information.@@arkadaurum298
It’s incredible how much these guys can talk without actually saying anything.
So the video went over your head?
@@spontaneousbootay 100% it did. So much fluff and showboating without actually answering anything. These guys should be in politics.
Can you summarise it?
@@lorenzomuhammad1715 they just explained how the motor neurons and muscle fiber spindles work. The soreness is like edema. You need to move the waste product out by massaging and moving the muscles in different ways.
@@lorenzomuhammad1715they didn’t answer anything because there isn’t a clear consensus on the subject yet; it’s an area of ongoing scientific investigation.
@@aclouti6 couldn’t they have just said that then?
I worked in exercise physiology, and consulted on research for 30 years. My opinion has been for about a decade that muscle soreness is the result of lymphatic vessels stretching as lymphatic waste is worked out of a muscle in the immune response to resistance training. Muscle get sore relative to the amount of lymphatic vessels that drain them, and things that promote lymphatic drainage reduce soreness. It also suggests the use of light workouts/sled work between workouts to accelerate the recovery and why complete inactivity in days after training slows down recovery.
Training 6 days a week, there is Very little in between time. Would you suggest ice baths to help this process?
@@zachdancy5828 No. Ice and NSAIDs actually block the normal lymphatic drainage and slow things down. NSAIDs by the way also block prostaglandin which is important for the hypertrophy response.
Hot water, heat, massage, light calisthenics. Training 6 days a week though you are probably in effect using workouts to help restore muscles you worked in earlier days. So if you do a chest workout one day, and then train your back 1-2 days later with some pulldowns or pullovers you are probably helping to restore your chest. If you only do your legs once a week though, you might want to do something restorative for the legs 2-3 days later like pushing and pulling a light sled.
Fascinating
@@zachdancy5828 Oh. by the way, cold shower is not bad. It promotes blood flow, but icing just congeals the lymphatic fluid like toothpaste.
Interesting. What "lymphatic waste" is in our muscles? Why is it there? Is it good to drain it? Is resistance exercise the best way? I'm dealing with serious doms right now.
My right shoulder is listening intently.
I never get shoulder soreness ,since 3 years... Of months of going on &off gym...I really don't know why...may be coz I does cycling.
@@Dr.Achuth_indiabut did you grow your shoulder muscles over this period?
SUMMARY: We don't know.
Still don't know what to do about it ?
This discussion is absolutely fascinating. We are so lucky to live in a time where we understand so much about the body that we can have these conversations.
Jesus dude answer the damn question
Ok they started saying that muscle tears/damage is not why you get soreness then they end by saying the exact opposite, that a loaded tension on the muscle damages the muscle cell wall to cause soreness. First off all it’s a contradiction and secondly we don’t have cell walls, only cell membranes.
Thank you so much for this valuable content! Keep on spreading your message 🥰
Personally I think a lot of this comes down to how we define "Soreness". So.. I had a Fusion about a decade ago now, and sometimes when it Aches I might say to someone "Bah my back is Sore" then give it a rest for a minute. However this is not the same sensation as say if I went to the gym and did a bunch of Bicep Exercises then the next morning felt the "Soreness" in my Bicep. While both sensations could be described as "Soreness" they are not the same. So I think a lot of that boils down to our descriptor of the Sensation and a individuals perception of their body and how they articulate that to others. Chances are if your Muscle Belie feels sore, you tore Muscle Fibers. If it's extremely sore your tore them badly. If you can barely move the muscle without sharp pain, you probably made a significant tear that will leave scar tissue.
Next question, is soreness optimal for growth/strength, or is active recovery to get that fluid/inflammatory response out of the muscle better? Better meaning leading to optimal growth/strength.
Dr. Mike Iseratel from renisance periodization covers this somewhat. Basically you need to let yourself get inflamed/sore in that first 24 hr period to get good gains but after that unsore yourself
I love being sore 😩😩😩 I know I’m alone. It feels so good tho 😫
you are not alone
I love stretching and rubbing sore muscles!! It feels so good!!
Same here. I was just looking for a UA-cam video about how good it feels to agree with me. Not sure why so many people think of it as pain and not enjoyable.
DOMS always discourages me from continuing a fitness plan. Useful tips were greatly appreciated
Every clip I watch of Galpin begins with him saying something haughty about the question being asked.
When he said stretching is the opposite thing you should do to reduce soreness and using low grade movement I immediately thought of Westside Barbell and their use for years of doing sled work for recovery. Because it’s only a contraction and no loaded eccentric movement involved it seems like the perfect solution. Do sled presses, rows, loaded dragging, sled fly and reverse fly movements.
Thats really interesting if you compare endurance vs strength soreness. The most pain i know is when switching between both extremes. For example heavy squads and jogging. From your explanation and my perception there are multiple sources for "soreness". When i go running the soreness kicks in quite immediatly after i'm 2h into it or after the start when the run is shorter. I would say thats an immediate response to wear caused by all those steps.
Strength training kicks in 24h delayed. Makes sense that it's linked to buildup and recovery processes and getting rid of liquid, mostly water, that is a byproduct of almost any organic chemistry.
I think soreness despite it's linkage to pain is a perceptional mechanism of our body to prevent injury. It prevents you from doing excessive exercises while the muscle is still recovering and favors light exercise that is primarly circulating liquids, not working the muscles.
Would love to hear your thoughts on that.
idk, I've had running soreness that came immediately, came 2-3 days later, and came the next day. I've also had strength stuff that showed up immediately, showed up 2-4 days later, and the next day. the only thing I've noticed between the two (I run marathons and I lift weights) is that I can have a hard strength workout stay with me for as much as a week, whereas the worst soreness I've had from a run has only lasted 4 days at the most. I can't even really hazard a guess as to why this is because I'm not a scientist or a doctor.
@@janemf I haven`t done a marathon jet but soreness kicking in 2 days + delayed is something i have never heard of.
Only idea i have right now is that you hit muscles that are still recovering from an intense strength session with an intense endurance session or the other way around. That way you get closer and closer to a propper injury in the muscle that holds for much longer.
@@MrHaggyywhen I was doing CrossFit 10-11 years ago, it was very common for everything to feel fine and then suddenly 3 days later (if I stopped working out) horrendous soreness would set in. it always seemed to be 2-3d out so my goal was to never take more than 1 day off.
Invaluable knowledge, thank you.
Very curious about Dr. Galpin mentioning free radicals being released from mitochondria. “Free radicals,” have bit somewhat of a buzz word the past few years, with emphasis being placed on trying to increase our antioxidants to minimize free radicals. Im curious if anyone knows whether this free radical release from exercise that Dr. Galpin refers to is healthy, unhealthy or neutral.
It’s the good kind of bad. Or. It’s a good reason to allow a bad thing to happen. Drinking alcohol is a bad reason, exercise is a good reason.
"radicals" are positive ions... their "free" when is just the ions floating around; calcium , selenium, magnesium 2+ ion charges...+ ion charges in the body are "acidic" = lowers pH.... most people are normally low pH = acidic....for complex reasons , normal goal pH = 7.36......most people are at 7.25 to 7.35 pH, acidic....eat more baking soda until your urine on test strips shifts up to around 6.7pH, urine is usually low around 5 - 6.5 pH
Anti Oxidants could possibly blunt the response from exercise. I am not the best one to explain this, but I believe it. Same for cold plunges too soon after exercise.
There are some aspects of this explanation that make a lot of sense, but then like all things it should be testable. If it is truly immune inflammation putting internal pressure on spindle cells, then some experiments could be validating. You should be able to measure that pressure with more pressure equal to more DOMs; visible resting tension and swelling in the muscle should also equate to more DOMs. Likewise you should experience less DOMs the lower the measured pressure. A muscle fully at rest but in a position it would be if fully contracted, completely slack, should feel less pain or no DOMs as pressure should be relieved.
This is always what I tell my clients when they are sore and it works for them really well. Just lighter versions of the exercises. Or a walk etc. To reduce soreness. Then I tend to look at other behavioral patterns that could be contributing. Sleep,stress management, caloric intake, etc.
How do they respond when you tell them "nobody knows, we need more research"?
@PaulG.369 I don't tell my clients that as it would probably confuse most, I tell them things that can help improve how they recover from soreness.
Why would you want to reduce soreness?
By reducing soreness you reduce adaptations. You don’t see bodybuilders taking inflammation downwers
Microscopic morphologic studies are easy enough to do on the skeletal muscle. In an appropriately applied exercise program/movement no damage to the functional unit of the muscle has been found. Scarring is the bodies normal response to muscle tissue damage not improved function with hypertrophy. If tearing or damage were the etiology of muscle damage from correct exercise the result would be crippling. It is not, it is in fact the opposite.
Could you please elaborate a little bit? Are you saying that muscle tears are not the reason for soreness?
@@georgia9406 Clearly, you have the ability to read my comment. To comprehend it and follow up with a logical question. Therefore, you are serious. I am close to saying that. There is no evidence on a microscopic level that indicates a disruption of the functional unit involved in muscle contraction. On any comprehensive and or reliably predictable model is this shown. Moreover, soft tissue does not heal from trauma in the manner that is congruent with any DOMS theory. In a nutshell, In most all cases muscle tears are not occurring at all in post exercise soreness. This discussion has been ongoing for over 35 years and still no one offers a solid answer. The discussion today is precisely that of 1982 and has not changed.
@@georgia9406 The confounding variables that go unmentioned in all the studies on this subject render the studies virtually useless.
@@georgia9406 Please explain your interest in this topic.
What about pain receptors in fascia?
lots, 10x as many as in muscle
Is there another episode/clip where he explains what he means by 'finish the metabolism' at 12:20? Could someone point me to it pls if so?
"Free Radicals are waste products...just like smoke from your vehicle exhaust......
Free Radicals causes this inflammation".......in my opinion...
Earlier this was thought be due to the lactic acid,produced from anaerobic pathways.
Look up electron transport chain, basically when breaking down carbon there is several stages, first is glycolysis, then pyruvaye oxidation the the kreb cycle then electron transport chain. That is the end result of carbon metabolism
If the inflammation and pain initiates muscle repair/growth, then why would you wanna take the fluid out of that muscle to alleviate pain ? Shouldn't you be letting the repair process run its course naturally instead of rushing things ? i.e rest and let the process occur rather than doing low intensity cardio.
no, there is lots of waste fluid inside a muscle, weak exercise contract the muscle so the waste fluid gets pushed into the lymphatic system, then to kidneys , you recover faster
Another thing you want is a lot of acid build up from electron transport chain and glycolysis so you want to add oxygen to these to remove them from the muscle
Pain has no mass but sometimes it is heavier than a mountain! That is stated in a deep movie trailer voice so it's more dramatic. 😅
I may be an outlier, but I am well trained with 7 consistent years in the gym. I have trained all frequencies and volumes but largely stuck 2ity low volume, low frequency due to soreness. I am sore 4-5 days post workout. I am 56 now but this was also true in my 20s.
i am 57 and just started getting sore all the time about a month ago. low volume heave and light day, about 4-5 days apart, i am sore same day as i lifted this time.
Hardest thing about listening to Galpin is he rarely breaks things down into layman’s terms.
This is a clip from a much longer episode where he breaks down and explains a lot of the terms he's using. Even still I think there's so much nuance and specificity here that breaking things down into layman's terms would actually be detrimental to understanding the topic, especially for those on the other end who want the specificity
I'm curious how diet plays a role in muscle soreness. I cut out sugar, vegetables and grains 5 months ago and no longer get sore the following day like I use to.
It could just be that your body adapted at the exact time you quit these foods by coincidence. May just be a timely coincidence, but I’m no professional.
Probably because you can’t train worth the shit anymore 😂
Exactly, I can do a workout and have carbs in my system and be sore AF I go carnivore and get the carbs out of my system do the same workout and not feel shit
I noticed no muscle soreness afyer as workout when fasting. I have done some pretty hard workouts too. Nice to know others have experienced the same thing.
@overlordfemto7523 I am in my 40's and have been training since a teenager. I also have my Masters in Kinesiology so I know how to train and I know how the body works. I just don't know why I don't get sore like I use to since changing my diet. Has to be something with the diet.
Any thoughts on high carb, particularly grains, causing more muscle soreness from increased inflammation?
I'm dealing with getting out of bed frequently to pee. I usually wait train after work around 4 pm, then dinner. I try to stop drinking fluids around 6:30 pm, but some night, I'm up five times to pee. It's very frustrating. I suspect I may not be getting enough fluid during the morning and early afternoon.
prostate
Thyroid ?
Enlarged prostate is my guess
Love it “ cell wall” when your describing animal cells . Hope that was a slip. However, joking apart some interesting points. What also MUST be considered is mechanical effects of cellular oedema on tendoni sensory fibres as this is where DOMS is mainly felt near muscle insertion points. Also why we get a lower immune response / reduced pain sensation as training progression ( time training/ years) continues.
So then if its inflammation, ibuprofen should be in protein powder.
Ibuprofen is the last thing you want to take if trying to build muscle!
cool thought.....but no.....work out just hard enough to be a "little sore"....or "isometric workout" leave almost NO SORENESS
What is inflammatory immune response??
Very informative!
Ok i agree 💯
I was streching the muscles and it was worse.
You need to move fluid out by resting and whit masage
This explains why doing Iyengar yoga on my off days really alleviates tightness and soreness from my heavy tennis workout days. 🤔
Ok so main takeaway delayed soreness 24-48 hours is not related to muscle tears. If it happens right after workout or during probably is muscle tears. Which is a different soreness so muscle tears soreness vs doms ?? So do with that what you can idk
do i understand this correctly that antioxidants may increase resilience to DOMS?
Yes I believe so. Well I think they may reduce the swelling and inflammation so in theory that should reduce the pressure of the receptors
Pretty confusing answer to a simple question. But very well explained.
So why does DOMS go away after a few weeks of rigorous training?
Degrees of muscle soreness have nothing to do with "gains."
What about tendon soreness and recovery
If you don’t know, just say you don’t know….
Also after eating carbs my muscles get instantly stiff.😳 what's up with that?
I experiment with keto diet, on and off for about a month very strictly, and when on keto diet I never experience muscle soreness, and when having carbs in a diet, I experience soreness almost every time, I train with heavy weight 2-3 times per week each body part.
No glycogen in the muscle from keto .
sus....very sus...
What about chronic muscle soreness not affiliated with exercise?
Iyengar yoga (and trigger point self massage) was one key to healing my deadline driven job related muscle soreness brought on by bracing, involuntary breath holding, and sitting for long hours to make my deadlines. Total game changer
@@nancycm I can't do yoga for religious reasons but I do employee dynamic stretching and it helps. Recently I took a long soak in Epsom salts and baking soda and it helped a lot. I'm likely magnesium deficient and I battle autoimmune issues.
This is actually just a game of medical ‘taboo’ (the game where you describe something without using key words). The key words they aren’t allowed here are
Lactic acid.
Fascia
This! Exactly 😂
what you state is definately 2 causes, but there are many more
Lactic acid is very obvious and if you listen to the full episode then you’ll hear him talk about that but lactic acid is not a problem when preforming aerobic training or if you training to run through kreb cycle, because lactic acid gets broken down during that process. So he is not talking about anaerobic training specifically
I think it’s indicative of muscle healing, because I said so
TBH: I think much of what purports to be new “science” is little more than elaboration of narrative twist, beyond any point of establishing causation or providing any utility. The way in which the subject gets talked about (in this case muscle soreness) implies new meaningful discoveries. You can always have a new “understanding” of something without ever establishing a new provable thesis with consequential effects.
This probably describes PEM - Post-Exertional Malaise - associated with ME/CFS
And they never got back to the original questions.
Doesn’t explain creatine use. It significantly increases intracellular volume yet one doesn’t get more sore..
you woukd have to be on an extremely LARGE DOSE of creatine!!! a gallon
I'm not sure where you are coming up with that. with as little as 10g/day you can easily gain 10lbs of weight that is presumed to be mostly intramuscular water volume. Way more than what you presumably get by inflammation after lifting. One does not see much weight gain after a lifting session.@@lunam7249
“Muscle tears” = 💪😭
I'm always pushing myself so I stay somewhat sore. No problems.
Wow, that’s fantastic
Brooooo, so is it good to be sore/doms or not?
Why did DOMS start 48 hours once I hit mid-40's? Soreness used to be next day.
You're not working out hard enough
Probably it could have be a signal of weaker immune system, and later inflamation response that is natural with aging, just my 2 cents...
natural process of "aging" and your fitter now....olympic athelete have notoriously slow DOMS 48- 80 hours later!!! this also rewards olympic atheletes to train more often and harder.....wheas people with 1 hour later DOMS are sedintary mo exercise people!!! great question!❤
Lactic acid build up is the main cause of muscle soreness diet and stretching and warming down can help reduce soreness but any kind of exercise can cause it especially when starting out of conditioning👍🏽
we know that, but this doc is refuting that....??
this is so weird, i’ve been dealing with soreness from a leg workout all week and then i get this video
what can u do;p
It was exactly the same for me. I talked with a friend if I could train with soreness this evening and this video popped up 😂
Your phone listens to you and the algo kicks in
to be blunt, if you're sore after a workout, you did too much
@@KenithCopelandfalse
Please bring on tom purvis on the podcast
Could you do class on BCP 157?🤓
'Huberman lap clips' -15 minute video lol
Hey Dr. Huberman, I agree with Dr Galpin on muscle soreness. I have found in my practice I teach my clientys how to allevaite soreness in minutes. IN using my technique, I see people every day that are in pain from muscles soreness when I gently touch them and within in minutes, I can press as hard as I want and the pain is gone. My technique includes self-massage, special type of stretching, not static or dynamic, and how the brain works with the tension in the muscle. I realize there is not a lot of studies in this area and nothing to prove what I do, but I am telling you, my clients 55 and above, are amazed at how quick the muscle soreness stops. I think it is worth studying. WOuld love to speak with in more detail.
I don't know the science. All I know is that it feels good
When you go carnivore, you don't get sore. Work on the same muscle group for hours and hours but never get sore. Much more research is needed considering this fact. It's fascinating how many things that happen to us including disease are all metabolic, including soreness.
0 muscle soreness on carnivore.
I was shocked, but it is true.
I love your channel. That's it, that's the comment.
Pain and soreness feel different
What a clear, concise explanation of the 3 questions posed. 🙄
Its when your musckes are sore after a workout 😎
I admire the work huberman is doing and i follow him a lot but these guys needs to be simplistic, this could have taken a lot less time than 15 min
Wow watching with a sore leg
Out of nowhere!! What a coincidence😮😮
They are listening
I have to say I was really disappointed with this one given how much we know about fascia now and it’s roll in pain, soreness, and proprioception.
Is this the old 2 bears set?
The complicated, evasive approach to answering the questions shows how little understanding this “expert” has. Politicians answer definitive questions by evading and redirecting.
Thought it was just me, I have no idea what muscle soreness is after this video.
Uh wtf is this comment?
@@kenmac13Nobody does, that's the point.
You know he is not simply answering 1+1, this is a very complex process that has a lot of factors that need serious consideration. What answer did you expect here?
Very interesting, cells are very complicated interacting with each other,one day humans might know everything
As usual, there’s too much to absorb in one listen. Always nformative.
The get to the fucking point already goats right here
These guys are reaching. It’s trauma, whatever you want to call it. The pain/soreness can onset within HOURS. For example, workout in the evening, the next morning you’re sore. Also activity (blood flow) can mitigate the pain/soreness (perception), so for example if you workout in the morning and you’re active afterwards you may delay the soreness/pain which is again PERCEPTION based. It doesn’t take 24-48 hours for the physiological part to START! The problem is that the soreness generally doesn’t RESOLVE in that time (24/48 hours).
i agree with you. except "perception" part, a bone break is REAL PAIN, you can see it electrically on discharge nerve fibers
@@lunam7249 let explain perception to you. Perception is highly subjective. That does not mean perception doesn’t have a physical trigger/stimulus. For example, a common perception scale we use in our exercise physiology lab is rate of perceived exertion (RPE). Does RPE have a relationship with physiological alterations? Sure it does cardiovascular strain, muscular strain, thermal strain, etc play a role, but can RPE be different if these strain variables are controlled? Absolutely. Let me further explain to you. Have you heard of an epidural, a “saddle block”? That blocks pain signaling to the brain. Does that mean that biochemical processes of pain are prevented at their root? The answer is NO. So, pain is very much perceptual. It relies totally on sensory triggers/afferent impulses to the brain. Block those pathways off and no pain, even though someone’s leg may be cut off. Have a nice day.
@@Bimmer_Bill i understand what perception is.....obviously , give everyone IV fentanyl and voila "no pain" perception.....however, im discussing "medical doctors" who wont even perscribe opioids for a broken ARM!!! alot of doctors are TERRIFIED of the FDA or FBI " claiming they "over-prescribe"!! so these scardy-cat doctors run around just telling every broken arm patient the "pain , is just all in your head"....gives the patient tylenol as kick them out of the E.R.....
what??
🎯 Key Takeaways for quick navigation:
00:30 🤔 ¿Qué refleja realmente la sensación de dolor muscular? No se limita solo a los músculos, involucra otros sistemas y tejidos.
02:55 🚫 El dolor muscular no es principalmente causado por "microdesgarros" en los músculos, como se creía. La inflamación y la respuesta inmunológica son factores clave.
05:46 🤯 El dolor muscular puede ser resultado de un bucle neural, no necesariamente de daño muscular. La presión sobre los receptores nerviosos de los husos musculares podría ser la causa.
11:28 🏋️ Realizar ejercicios de baja intensidad después de un entrenamiento intenso puede ayudar a aliviar el dolor muscular más rápido que descansar por completo.
13:22 🔍 Se postula que la liberación de radicales libres de las mitocondrias puede desencadenar una respuesta inflamatoria en los músculos y contribuir al dolor muscular. Más investigación es necesaria para confirmar esto.
Made with HARPA AI
Nothing was spoken in regular English for me to understand lol
Everybody is trying to reinvent the wheel. The reason why it's delayed is your body's natural pain killers wear off. When the endorphins wear off within 24 hours you will start feeling the pain from the micro tears. It's not some weird psychological feedback loop! Geez people come on!
That ‘weird psychological feedback loop’ is pretty well proven to just be how your brain and nervous system works. I’m not sure endorphins have ever been proven to ‘block pain’ what books have you been reading
ah the old sliding filaments and sarcomere😊
Why does a person on the carnivore diet no longer experience DOMS?
Same question. Or atleast lessens soreness compared when Im eating carbs
Interesting, I recently heard on Dr. Anthony Chaffee's you tube channel that we feel less to no more muscle soreness after an intense workout because we are no longer experiencing the inflammatory factors in plants. I certainly have felt this happen in my own body once I started on a zero carb no plant diet. I have a physically demanding job and my elbow and knee pain are practically non-existent now.
@@arnelcatangayjr2878if it’s so to inflammation carbs seem to cause more immolation? As you are bloating
Yeah, I no longer feel sore after supper-heavy lifting.
@@deadbones23 if the question is why does carbs make muscles sore, one reason is chronically elevated insulin leads to inflammation in the body. Every time we eat, insulin is released. Eating 3 meals plus snacks in between, means insulin is always high. The carnivore diet usually consists of two meals a day of fatty beef. The protein and fat makes us full, so we are able to go 16 hours without eating easily. The insulin drops low during fasting hours, causing fat stores in the body to be released and people lose weight fast.
Try quantum touch healing on your Dom's
Watching with sore legs lol
imagine a charley horse in your pecs like a day later, thats doms
So he didn’t answer the question with any great conviction of evidence.
That makes a lot of sense! My take away from this is do your leg day or whatever then have low intensity muscle movement of that same muscle group maybe throughout the same day and following as well, drink extra water to help this "pumping out of muscle", and take liposomal vitamin C to increase your macrophage activity(which can be seen on microscopes reaching out and grabbing toxins and pathogens...acting like a cleanup crew more of less. Testing this tomorrow. Good information, thanks.
Very interesting. I had no idea liposomal vitamin c even existed. Quick search shows that it enhances absorption and bioavailability. Think I might start taking it 🤓
I don't think there pain receptors anywhere in our body. How would 'they' know what 'pain' is. We do however have a fantastically complex nociception apparatus which will light up when a specific (or non specific in the case of chronic pain) receptor is stimulated enough. That threshold will vary on our level of fatigue; nervous system sensitization, past experiences, etc... What do you think ?
This did not have to be 14 minutes long
Of course, it's not muscle tearing. This ridiculous theory has been pushed for 40 years.
Won't get that time back
Maybe ice therapy for soerness????
DUH......UM WHAT. TALKING HEAD. 😅 I JUST WASTED MINUTES OF MY LIFE😂