Protein Trafficking
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- Опубліковано 2 бер 2008
- NDSU Virtual Cell Animations Project animation 'Protein Trafficking'. For more information please see vcell.ndsu.edu/animations
Protein trafficking is used to describe the process of moving proteins from the rough ER, through the Golgi apparatus, where they are modified and packaged into vesicles.
There is no better explanation then visualization. Thank you for upload. Also did anybody think it was trippy how the vesicles where budding from the Golgi? It was like creatures crawling from another dimension.
gotta love the creepy intro music...
LOLLL 😭😭
Thank you for taking us through an amazing journey
In the Golgi network, transportation may occur through one of two models: cisternal maturation model (the whole stack matures) or vesicle transport model (stacks always remain the same; more likely model).
hey your videos are amazing .but could u throw some light on cop 1, cop 2 and clatherin coated vesicles
Astounding! I never studied cellular biology beyond high school physiology, but this is fascinating
Thank you! This video helps me a lot!
Thank you so much. This video made me clear my doubts very effectively.
the video is so helpful, thanks for making!
I finally get it.....Great vid. Thank you!!!
incredible. love this animation.
Thanks a million!
thanks so much! great work with the video, really helped! I agree, Priceless!
Does anyone else start to fall asleep while watching this? Almost too relaxing.
Great video, this helped a BUNCH!!!
More helpful than the lecture ;) Thanks
If this doesnt make you believe in a higher power and divinity I dont know what will. No other words could ever capture the complexity and startling sophistication of these systems.
how i wish we had professors like u guys in university...... first , to understand the subject so clearly and then to make such beautiful video takes a lot , and for others to upload it for free , makes me still believe in humanity !!! thank u lots
kinda curious where u at now and are u doin fine in life and btw I am a 1st year med student if youve got any advice
Very good breif and short explanation and ya good animation as well .thank u
Thank u sooo much ...this video really helped me .....
This is briliant, thank you, for this. live Science!
huh... its so much easier to learn abt genetics now...... thanks a ton .... u r a boon to students like us
unbelievable scenes!
thanks.. this video hopefully will save me😍
Great video, thank you.
I would love to see a video on ribosomes. Something about how they are made and assembled..all the «traffic» into and out of nucleus until they are done.. including the manufacture of ribosome 45 S..the only one made in the nucleoplasm. Thank you for your vids!
thank you
beautiful
Excellent
thanks, it was helpful for my presentation
really this video is very very awesme
very well made
thank you!
Thanks a lot.
Great video!
Great, just a quick question, how do you maintain the reticulum's membrane equilibrium if the cell keeps sending vescicles, where do the cell gets the materials to maintain those membranes like in a constant way.
Golgi is awesome!
Tnxxx,keep up the good work
Thanks
nice voice...wonderful video...love it
Once again a fab video. Thank God for youtube because bio isn't as hard as professors make it out to be. Thanks keep up the videos please.
its the maturation model of the golgi apparatus instead of the vesicular formation model
The cis-maturation model is the dominate model of transport in the golgi; however, there is evidence that may support a combined model with vesicle transport. There remain several interesting unresolved question such as why some COPI vesicles contain cargo rather than golgi enzymes and move anterograde rather than retrograde. It has also been shown that some cargo may actually travel slower than the cisternae matures.
Great vid! *****
thanks! I finally got it =)
amazing!! ^^ thx..........
Does this type of protein trafficking respresent exocytosis or endocytosis????
Need more details for coledge student.
but they didn't put the retrograde movement of golgi buds, which restore enzymes to the new cis golgie...
I came here looking for information on how proteins are transferred because it occurred to me that there is no information on what happens to the mRNA spike protein after the vax. They only say the mRNA is broken down but not how the spike gets out of the cell. The synthesized mRNA needs to be covered in a lipid structure to fool the cell into accepting it but then it must also be able to leave the cell for antibodies to attack. However, after watching this, it is clear there needs to be a coating on the protein to determine it's delivery location. What/where is this instruction to tell the body what to do with the spike protein? Do they just burst out?
@mattd2008 No cell bio is amazing the only thing is that is a lot of material to be condensed!!! But any how it is very interesting!
2008 wow,,where is she now miss christina johanson,,,thank you
Trying to understand what golgi boby is for 2 years?
Today i discovered myself that
Now you do
Yes it was helpful
That voice is the only reason i understand :D
the intro music is creepy afffffffffff
If the cisternal maturation model is a thing, and the vesicles become the cis cisterna, and then the old cis becomes the medial, where do the enzymes come from?
Confused me too, found an explanation from a journal article - "the characteristic distribution of Golgi enzymes is explained by retrograde flow. Everything moves continuously forward with the maturing cisterna, including the processing enzymes that belong in the early Golgi apparatus. But budding COPI-coated vesicles continually collect the appropriate enzymes, almost all of which are membrane proteins, and carry them back to the earlier cisterna where they function. A newly formed ciscisterna would therefore receive its normal complement of resident enzymes primarily from the cisterna just ahead of it and would later pass them back to the next cis cisterna that forms."
if the protein into the vesicle is tanget to go to the membrane and then out of the cell and this doesnt happen, we can say that there is an muntat in the SNAREs proteins???? please help
There are two different types of SNAREreported to be involved in secretory pathway, which includes v-SNARE (vesicles) and t-SNARE (target). Absence of any of these SNARE would result in the accumulation of vesicles in the cytoplasm.
(Bonifacino and Glick, 2004; Ungar and Hughson, 2003; Burriand Lithgow, 2004).
ohh yes i know that....ok i was studing for an exam ,and it was a question
lol I’m seeing this after 4 years✌🏻
It happens in eukaryotes?
Thankssss now i can pass my exam
Did u pass ur exam?
I am from Pakistan! your video is very good . please give me exact information about mechanism of protein trafficking.
@mattd2008
DON'T HATE
who´s here because of school? :D now YT sends me recommended videos of this type cuz they think it interests me :D
Labilis you should see mine...
And BOOM I understood!
Thankssss no i can pass my exam
جاي من طرف KSAU
if secretoy proteins are isolated from
secretory vesicles and injected into the cytosol,
it will be
I mean it will degraded in the cytosol or it will
be taken up into the rough ER and follow the
secretory pathway
Which answer is the true one
ta chido XP
@1imax111 And BOOM i didnt because i dont speak englisch very well...
damn proteins coming over here.. STEALING OUT JOBS!!
god, cells are so creepy
online schooling anyone?
بايو الحرس أينكم؟ هاتوا لايتس أنفداكم😂🤌🏼
Why cant professors teach like this!
@1imax111 naah rather wanna play some Cod, sorry. :D
ide gas 2020 corona brate
Thank you!
:D
,
K hai ya chori
Vi creque kero
I hate cell bio
Do you still hate cell bio?
@@SARAH-on8dr abso-fuckin-lutely. I come to you from the future, it only gets worse.
@@SARAH-on8dr go to law school
@@mattd2008 😂😂😂😂 too late I’m almost done with my first year in med school
@@SARAH-on8dr you’ll see.