When my husband was in university, one of his dorm mates got scurvy. He'd arrived from home with a suitcase full of cans of baked beans, and that was all he ate for months because he was trying to save money. The hospital he ended up in couldn't work out what was wrong until a doctor who'd worked at a seaport hospital saw his case - he'd seen plenty of cases of scurvy in sailors who came in on slow freight ships.
That's funny. Where I went to college a lot of people only ate fruit because everybody lets you pick them from their trees. Otherwise most of our diets were canned goods and alcohol. Our ancestors were also the ones who (in recorded history) first suffered from scurvy in big batches (may sailors at a time I mean) :D
I read a book years ago about the Yucatan peninsula. It was written by an explorer in the 1800s. He said that scurvy was a real problem despite many orange trees. The people thought that oranges caused infertility.
"...So that guy chopped off my balls on this remote island and then fled with our boat, leaving me behind. Luckily i had those thingies, whatcha call em, Oranges as food, was hard enough already to not totally bleed out. But anyway, when i finally managed to build a raft and come back home... guess what, I COULDN'T MAKE ANY BABIES ANYMORE. Damn Oranges! No one should eat those!"
You forgot to mention why the Brits are called limeys. Scurvy on long ship voyages was a really huge problem that the Brits solved with long-keeping limes.
Maybe it'll be possible to use CRISPR to put it back and make functional, maybe even in adults after all vitamin c is normally produced in the liver so it's probably possible to introduce modified genes directly into the liver to jumpstart the process.
When I first went on disability I got scurvy. Fortunately I recognized it right away and bought some vitamin C supplements. My teeth started to hurt and loosen up. Thanks to my anthropology training, I knew why my teeth hurt. Being poor sucks.
Future Alien 1: My cloned humans keep dying! Future Alien 2: Did you feed them Vitamin C? Future Alien 1: No, why? They don’t make it? ...why were they top lifeforms?
Who said we’re top? And why should we be considered top? We build homes? Use tools? To me it’s mainly one thing, that we can pass down knowledge without having to experience it firsthand, I don’t need to touch a radioactive material to know it might kill me, I don’t need to use an electron microscope to see that it works and I don’t need to solve the math to understand why it works. THAT is what makes me think humans can be considered a top life form but even still, we lack quite a lot of useful skills
Former friend of mine went through a phase where he said if he gave up food, his stomach wouldn't get as upset when he drank all his calories. Had a change of heart when his mouth started bleeding and all his hair went curly.
@K T I think that would probably be a very good idea, especially since people think that scurvy is a joke since it's associated with pirates however a new name for the disease might change the view on it, especially since DeficienC dogs doesn't roll off the tongue as easily.
Fun fact, every year around finals week my old college used to have to put up scurvy PSAs. This is because, on SEVERAL occasions, students have gotten scurvy from neglecting to eat when studying. Higher education, y'all
I was gonna say the same thing! There were people at Uni getting scurvy cause they lived on purely ramen and red bull or something stupid like that. It's absolutely nuts how some people don't know that eating your fruits and veggies ISN'T a choice. It's a you can get sick and die if you don't thing.
Recently listened to a book that covered this and similar issues called "Human Errors: A Panorama of our Glitches, from Pointless Bones to Broken Genes" by Nathan H. Lents.
I remember that my biochistry teacher said the same: That we lost it because we (our ancestors) kept eating fruits with vitamin c and therefore we no longer had to produce it by ourselves. But I didn’t know that most fishes couldn’t produce it either. Does anyone know how do they get it in their enviroment?
He wasn't actually right though. You lose genes through genetic mutation that doesn't negatively impact offspring survival, not because you don't need them.
@@cookeymonster83 good point in detail, but not needing them is what makes them not negatively impact offspring survival when absent, which means mutations that happen to cause them to be absent will be passed on just fine. In other words, what the teacher was mentioned to have said was not plain wrong but rather a simplification that may very well have been justified in its original context.
Fish food chains start from phytoplankton and and other autotrophs. They can simply get vitamin C from consuming stuff in the foodchain. Fun fact: fresh meat has vitamin C too (since animals make them or get them from food) which is why the inuit don’t get scurvy.
@@just4deez its mostly stored in the organs though, the meat is actually the nutritionally least valuable part of an animal. (Had to add this for all the meatbois out there :P)
He also fed them fresh lemons, oranges, onions and cabbage, following the advice of James Lind, a Scottish naval surgeon, who wrote, "Treatise on Scurvy" in 1753. 👍
My mom's husband can tell when I ate sauerkraut the day after I do so. Food comes out of your skin, but I imagine basic B.O. on a ship of sweaty unbathed sailors would be overwhelming in general.
There’s new thinking about appendixes having a function of re-populating your gut biome after episodes of serious distress. Sort of a depository of your good gut bacteria to help jumpstart your system after say, cholera or dysentery, etc.
Most mammals are born with with heads and brains that are as large or nearly as large as they'll every be; humans, because of the narrower birthing canal due to walking upright, are born extremely prematurely and their heads and brains grow substantially after birth. The fact that human heads and brains grow after birth detaches any relation between hip size and head size.
I’d always thought that when we got comfortable with human genetic engineering we should re-enable vitamin C production, but it sounds like that will slightly increase cancer risk, and (at least with current tech) cancer risk is a much bigger deal for most people.
I still think it would be a net benefit. Most free radicals are dealt with in short order by the bodies defenses with things like vitamin e or other compounds that make things like blueberries antioxidants.
@@Satan666Official No, it was just a stripe bleached into his hair... you can see it in older videos. Him styling it like that predates his UA-cam career, so it's just rare to see him without it.
Great video about an important topic! In addition to being required to synthesize collagen, (which makes up 25% of ALL the protein in our bodies), vitamin C is required to make PAM, (peptidyl alpha amidating mono-oxygenase), an enzyme required to activate CRH (corticotropin releasing hormone), growth HRH, calcitonin, gastrin, oxytocin, vasopressin, secretin, and Substance P; enables absorption of iron; and finally vitamin C is necessary to make noradrenaline. Just sayin'..... ☺
@@herbbowler2461 Hmm. What does it flush? Because I take a lot of it and now am wondering if it is flushing out stuff that it shouldn't be. Like minerals that I need.
@@anyascelticcreations If you mean vitamin C. It flushes out free radicals that cause cellular damage. It is necessary to metabolize many other nutrients. Including minerals.
@@anyascelticcreations You're welcome. When it comes to vitamin C. The body uses it best if you yo. yo the amount taken. High dosage for about 2 weeks followed by low dosage for about a week. If a high dosage is taken for a prolonged period of time the body will over flush. Causing a vitamin C deficiency. If the vitamin C does not contain bio_faviniods it can irritate the kidneys. Good health.
Had a grapefruit earlier, so I'm safe for the next few weeks. Like really, you need a serious deficiency to develop scurvy, an orange a week is plenty to avoid it! Edit: Totally forgot about the lemon juice I put in my water every day, actually I'm completely safe!
Since _none_ of us have a functional GULO gene, it sounds to me like it was both the slight advantage of not having it (provided you get enough vitamin C from your diet) _and_ the lack of a disadvantage due to our ancestors’ diet.
I'm not really sure of the advantages of not having the GULO gene, but given our ancestors' diets had plenty of vitamin C, there probably wasn't any selective pressure to keep making it ourselves.
@@tristanssimpson1324 that should have just made it more of a random thing if people had it or not. In order to actively breed it out of the entire population, there had to be an evolutionary advantage to no longer produce it.
So we have a broken gene, and we know how a good gene should look like. And we have a CRISPR-Cas9 that could find a sequence and replace it with another sequence. Let's start by fixing Guinea pigs?
That would be pretty cool :) My first thought for the first human-oriented gene therapy for otherwise healthy people has always been disabling the myostatin genes. (People with two copies of mutated myostatin genes end up with extra muscle mass and extra strength, with no known negative effects.)
My aunt is actually severely allergic to vitamin C, and she's gotten scurvy a few times. The doctors always have to administer the vitamin C really carefully so she doesn't go into anaphylaxis. She can't even so much as smell an orange without her throat swelling up.
Vitamin C is in organ meat, all types of citrus, berries and many legumes including peas. does she not eat peas or lentils or organ meats? Citrus allergies are common I am allergic to oranges for example. I do not think it is possible to be allergic to something that the body requires perhaps I am wrong but I have not found any studies that proved and allergy to something your body needs to be healthy.
@@annak804 Oh, it's possible to be allergic to lots of things your body actually needs to survive! Although it's very rare, there are documented case studies of aquagenic urticaria, or water allergy. In fact, I am allergic to all citrus, all nightshades (ie tomatoes and potatoes), all latex bearing fruits, and a bunch of green leafy veggies. I get my vitamin C from berries, watermelon, broccoli, and sweet potatoes.
I have EDS, so most of the scurvy problems arise from the fact my body can't make good collagen in the first place, genetically. And boy, I can get very painful.... I have a high pallet and small mouth, leading to overcrowded mouth problems, I got 12 teeth removed, 4 baby teeth, 4 adult and 4 wisdom teeth. I got scoliosis, ripped skin, Snowy vision syndrome, joint pain, chronic pain, Barre Lieu syndrome, migraines...
That's a question for an evolutionary biologist. The amount of time depends on how much money we throw at the problem (e.g. COVID vaccine, moon landing, Manhattan Project, etc.)
@@__--__ In this case vitamin c is or would have been usually produced in the liver it might be more available to more people than other genetic modifications (which would have to be done while the person is still an embryo) it could be as simple as introducing modified genes directly into the liver. So so so so this probably wouldn't be a problem like designer babies, could probably be done to anybody (maybe they would make it as a scurvy vaccine for developing nations).
The question is whether we should make some of these pseudogenes useful again by mutating them. The gene for gulo probably isn't worth the effort since vitamin C deficiency is easier cures by handing out some orange juice but there are others that certainly are interesting.
I'd like to produce some blasted melanin. I hate having to bathe in SPF 50 every hour outside in the summer to avoid turning into leather here in freaking Oregon. Even so, I still freckle through it. And don't give me the vitamin D defense either, because I still need to take supplements for that.
Scurvy is a huge problem in developing nations where people have trouble finding the right things to eat, also with the decline of the bees fruit production will decline as well so vitamin c might become harder to get in the future, maybe it would be worth looking into this now so that when these inevitable fruit shortages arrive humanity will be prepared to deal with it.
I wonder if not synthesizing a vitamin you have plenty of in your diet can make your metabolism more efficient. Also, Michael sounds very mysterious today.
The way I was brought up, I couldn't even imagine, humans could live without fruit and vegetables. But scurvy in a developed country seems to indicate that people actively avoid fresh foods. Vitamin C is the most readily available vitamin in natural foods after all...
Or it's an indication that nutrient-rich foods have something affecting their availability to certain portions of the population. So we look at the groups which are most affected by this and oh hey it's the poor. Being poor makes optimal nutrition more difficult, from the dearth of cheap-yet-nutritious options - as well as the time/expertise to properly utilize them - to the plethora of easily prepared, energy-rich but nutrient-poor alternatives stocking most American shelves. Add in the fact that the latter are formulated to have textures and mouth feels optimized for dopamine production, and it becomes a lot less "people are avoiding fresh foods" and a lot more "people without reasonable alternatives are having highly addictive substances in food form pushed upon them from birth."
It would be interesting to gene edit some other primates to correct the mutation to see if there were any downsides of being able to produce vitamin C.
It’s probably just that it happened to mutate and we had enough sources of vitamin C externally so it faded away from the gene pool bc it’s a needless use of energy if it’s already there
pizza hut seemed convinced at some point this year that one could prevent the spread of scurvy by washing one's hands, as per a handwashing graphic which was posted also claiming one could prevent the spread of hangovers.....
hydrogen peroxide, although not a free radical, is a reactive oxygen species in of itself. Contrary to popular belief, it is not the biochemical sources of ROS that are problematic but a disruption of its finely regulated homeostasis by stress factors. However, the stress can be considered a signal and the ROS imbalance is a biological signaling method cascading downstream. Furthermore, ascorbic acid (vit C) is a nonenzymatic ROS scavenger, which in the worst case scenario could theoretically reverse the oxidative damages caused by the H2O2 produced from the production of vit C
I don't know. The part about rabbits and goats regulating their GULO output makes me think other genes are involved, and trying to find and fix *all* of them... So without the regulatory framework, maybe you'd end up with way too much or way too little, or maybe your body would be *able* to synthesize vitamin C, but would never actually produce any.
bro i think you got the evolution part a little bit wrong.....EVERY mutation or change in the history of life since its creation has always been random. Cell or genes are not conscious in a sense that they can plan a mutation or think like "okay lets see what happens if we alter this gene and if doesnt work we simply reverse it". In reality mutantions are random and if the particular mutation gives some advantage to that individual from other individuals of his species then the likelihood of survival that individual increases and therefore that gene has more chance to get passed down and over time the population of the gene carrying that mutation is what remains.
@@harishsingh5491 Never thought Cells and Genes were conscious. I was thinking about change and adaptation overtime. There are people that can't eat certain foods because of they aren't used to that type of food. Even if this isn't the best example, It doesn't mean that Cells and Genes being conscious is implied. But I do understand why you commented. "Necessary" was the wrong word to say. My bad.
@@afrikasmith1049 yeah you are spot on, that "necessary" was the reason i wrote that just to convey that their is no plan or purpose in mutations, they are just simply random. I just framed it in a wrong way. It is my bad too, i should have written "As you know cells and genes are not conscious......".
Free radicals are NOT just free floating electrons. They include the naked proton and the OH- radical, just for starters. Some of these free radicals, especially in the case of radiation, can also be thermally energetic (hot) which can cause further cellular damage.
I once cut vit c out of my diet to improve the effectiveness of a certain medication and before long I has tender, sore gums and pain in my knees and shoulders(I was 20 y/o).
Depends how northern. Lots of evergreens have very high vitamin C content in their needles, so spruce trees are a major source. Failing that, they can eat animals which produce their own.
@@Primalxbeast Guy in my dorm in college would get in fights with his grandmother about the need to eat it since they could now get orange juice at the store.
A friend of mine had scurvy for a bit. He ate 2 things ever : frozen chicken nuggets and lemons. He liked the lemons cuz they tingled. Doctor says to stop eating it because hes allergic and eat different things, but he stayed with eating only chicken nuggets. Then he goes to the doctor cuz hes bleeding a lot and he feels bad all the time and he keeps getting cuts.
"Any thing about booty is a good time"- "And if you wanna experience some of that for yourself" I honestly thought we were getting a Sci Show hookup app.
I wonder if that's why some people can handle an all meat diet without getting scurvy, they are getting the collagen directly without needing to rely on a vitamin to chemically build it? It's undoubtedly more complicated than that but I'm curious if anyone has looked into it?
There are some meat products that contain Vitamin C, like certain whale parts, which is a large part of how some Arctic peoples like the Inuit (Eskimo) have traditionally gotten by. I'm no expert and agree that it's interesting to look into. I'm sure there are research papers out there.
Scurvy: *is mentioned* College students who haven’t eaten an vegetable in three months: *have entered the chat* Edit: Guys, the an is supposed to be comedic, and stop talking about stereotypes, I say “college students that haven’t eaten a vegetable in three months” not “college students” because I know not all college students are stupid. I’m not talking about people who can’t afford vegetable either, I’m literally making a joke about people who chose not to eat fruits or vegetables. Stop arguing
xenophanes Except your dumb ass stereotype about college students smoking weed & is just that. Ever heard of the triangle? Education, social life, health. Choose one.
What about people with allergies to citrus? Do they often run into something like scurvy, and what are the common supplements they take to correct or prevent that?
Scurvy also leads to any and all scar tissue breaking down, which leads to every wound you've recieved in your entire life re-opening and every bone you've ever broken re-breaking.
Ben Bova made a point of in "Mars", when the Mars mission nearly failed because a meteor strike destroyed most of their vitamin supplies and nobody noticed until nearly too late. None of the scientists had scurvy on their radar :)
FUN FACT: Traditional Lacto-Fermentation of cabbage (as in sauerkraut made without accelerators such as vinegar) increases the vitamin c by a factor of 7! So it takes it from 100 mg per cup to about 700 mg.
I like how they said developing nations and then the USA like there’s supposed to be a difference. No universal health care you’re basically a second world country lmao.
Yes, it's more difficult to survive here than many people in other countries think. There is a ton of poverty and illness here. It's just not what is shown in the media. As someone who has been sick for most of my life and is unable to afford healthcare or to work outside the home, I am very familiar with that. I have also seen bits of what it's like for the homeless here. The lives of a lot of people are not very first world here.
Funny how people typically think of citrus fruits, while they aren't even the winners in tems of Vitamin C content...Well played with the thumbnail there, SciShow ;)
Citrus fruits are still a good example though. Most people can easily find an orange and are likely to be willing eat it. So yeah they may not be the vitamin C winners but it's something that we can probably get into your diet simply and quickly. It doesn't matter how good a food is for you if you just won't eat it for some odd reason!
Biomed Master Funny enough, citrus actually got its reputation for being high in vitamin C because, when it was discovered why sailors were getting this strange sickness called Scurvy, those seamen would haul crates of oranges and lemons with them because they lasted a long time at sea without rotting or over ripening. So while, yeah, it’s not the most “efficient” way to get vitamin C, it was the most practical for shipping crews.
I think the non functioning gulo gene was past down because our distance ancestors were around lots of vitamin c rich foods so it didn't matter. Now if they were in a environment with no or very little vitamin c fod sources this mutation would of been a deadly.
Growing up in a developing country myself, i never knew scurvy was actually rare in developed nations. I thought everyone got scurvy once or twice every year
It depends on where you actually are I guess. As someone living in a developing country myself, albeit a tropical one, I've never heard about scurvy until I read about it online.
Many modern processed foods are actually fortified with vitamin c, of course not all of them are or can be but that makes it significantly harder to get scurvy, of course not all of them are so it is still possible it's just more difficult. Honestly with how badly people eat nowadays this is definitely a good thing, I imagine scurvy with me much more well known in developed countries if this wasn't done. Note: vitamin c is also called ascorbic acid, so if you see that on the ingredients list then you know that that food has been fortified with Vitamin C
Yet we have such big brains that we can craft better versions of everything you mentioned. Knives, metal claws, airplanes, and armor. I think that's cooler.
@@Burn_Angel well yeah, but from an evolutionary perspective it would be awesome if humans weren't so squishy, helpless offspring, vulnerable females, prone to diseases, extremely slow to mature, not enough body hair to protect you from the elements (but just enough to be considered unsightly) but you're right our ability to turn a stick into a club was the game changer, but all we appear to have as a tactical natural advantage is melanin skin pigmentation 🤔
@@OpEditorial You're underestimating humans. We have a much higher resistance to diseases than you might think, mostly when we have the best food we can produce, as we need plants and livestock to be the best food sources they can be, and if you combine that with our cooking skills, you get a lot of nutrition, which while it doesn't make us invincible, it does raise our defenses quite a bit. Being omnivore adds a lot to that. Also, having almost no body hair is actually one of our best traits. Humans are the creatures best adapted to long distance run in the world, and having no body hair allow us to cool off faster AND it lets our sweat spread easier, cooling us off even more. And while our upstanding posture help us to run better, its main addition to us is balance, which in turn made our skill to throw stuff more precise and strong. And when you're throwing pointy sticks, that's deadly to anything, no matter if you're an oversized sloth or a big hairy elephant. I recommend you to watch TierZoo, in his video about humans, he explains my points in better detail, and you might fall in love with his...format.
@@Burn_Angel well yeah, but it would still be cool to have at least one of the adaptations the animals (we're currently driving to extinction) have, retractable claws are awesome 🤔
@@OpEditorial Well, at least we can do stuff like seeing in colours, or being able to taste sweet stuff. Dogs and cats have none of that (respectively). And we live enough for our intelligence to build up a lo of knowledge, unlike octopuses. And we have hands that allow us to use tools, which would be possible for a lot of smart animals like pigs, but unfortunatedly they can't. And again with tools, we can use shovels to excavate and hunt down prey that hide in burrows, which would be awesome for animals like coyotes. We are really awesome in our own way, don't forget who's on top of the food chain c:
I adopted a Guinea pig who had scurvy. He had been neglected and never had fresh food. He survived for 3mo after I got him. He was scaly with hair loss. The companion he was surrendered with passed less than 24hrs after. Elvys looked a bit like a goblin when I got him. Made sure he had a good life, even had a gf, though they weren't allowed to even try to make any babies
Go to Brilliant.org/SciShow to try their Logic course. The first 200 subscribers get 20% off an annual Premium subscription.
i hate math
idiot
I have no understanding of math stop trying to ruin my brain
Can I just pirate it, instead?
I didn't forget how you bitched out Hank. Ill downvote every video of scishow because you were a coward Hank
@@jordancase11 what do you mean?
When my husband was in university, one of his dorm mates got scurvy. He'd arrived from home with a suitcase full of cans of baked beans, and that was all he ate for months because he was trying to save money. The hospital he ended up in couldn't work out what was wrong until a doctor who'd worked at a seaport hospital saw his case - he'd seen plenty of cases of scurvy in sailors who came in on slow freight ships.
That's funny. Where I went to college a lot of people only ate fruit because everybody lets you pick them from their trees. Otherwise most of our diets were canned goods and alcohol. Our ancestors were also the ones who (in recorded history) first suffered from scurvy in big batches (may sailors at a time I mean) :D
Scurvy is very common, I’m surprised the doctors were so incompetent.
@@DustyHoney ua-cam.com/video/vN9GR6xRw24/v-deo.html
@@DustyHoney you really shouldn't be at this point
@@sebaschan-uwu I shouldn’t. I’ve never met a competent doctor. Generally they sell opioids on the side.
Did you hear about the pirate suffering from scurvy?
His attempts to cure it were fruitless.
Sebastian Elytron xD
Soooooo bad!😋😜🤪😝🤣
You might think a pirates favorite letter would be R, but it is actually the C.
I'm pirating this pun
@@tompossessed1729 😋😜🤪😝🤣
I read a book years ago about the Yucatan peninsula. It was written by an explorer in the 1800s. He said that scurvy was a real problem despite many orange trees. The people thought that oranges caused infertility.
"...So that guy chopped off my balls on this remote island and then fled with our boat, leaving me behind. Luckily i had those thingies, whatcha call em, Oranges as food, was hard enough already to not totally bleed out. But anyway, when i finally managed to build a raft and come back home... guess what, I COULDN'T MAKE ANY BABIES ANYMORE. Damn Oranges! No one should eat those!"
Death is the best infertility
How the hell does this have 2 ghost replies, where are they?
EDIT: *Generic AI generated response for getting likes on a UA-cam comment*
@@ancientburrito9893 We’ll never know.
@@ancientburrito9893 it's been like that, for weeks I've seen one ghost comments on every comments
You forgot to mention why the Brits are called limeys. Scurvy on long ship voyages was a really huge problem that the Brits solved with long-keeping limes.
I was meandering through the comments, thinking, "Do I have to bring up Limeys?"Then here you were.
@@christelheadington1136 Me too, then I saw LadyAnuB's comment. Then I thought about replying to it, but then I saw your reply. Enough said.
But, ironically, limes didn't have enough vitamin C, and should not have replaced lemons.
And you know how long it took for them to go from a Dr. stating that to actually ordering ships to carry citrus fruit on them - 150 fricking years.
LadyAnuB
That’s cool! Had no idea.
“Humans lost the gene to make or own vitamin C.”
*Sad pirate noises*
Imagine eating something other than hard tack and measles absolutely disgusting
Maybe it'll be possible to use CRISPR to put it back and make functional, maybe even in adults after all vitamin c is normally produced in the liver so it's probably possible to introduce modified genes directly into the liver to jumpstart the process.
*vitamin sea
DNA is like a hard drive that hasn't been defragmented for 600 million years.
Best comment
@Marco Polo do you not know what defragmenting is?
accurate.
@@SimuLord
That's oddly specific but relatable.
checkmate evolutionists
When I first went on disability I got scurvy. Fortunately I recognized it right away and bought some vitamin C supplements. My teeth started to hurt and loosen up. Thanks to my anthropology training, I knew why my teeth hurt. Being poor sucks.
What's a pirates favorite letter? You think it be arr but it be the sea.
Loki Featherton 🤣🤣🤣
I thought it would be the P. It is an R with the leg removed.
@@blackpackhomesteadchrisand7337 Without P, they'd just be irate
ROFL! 🤣 😂 😅
@@coryman125 R remove the right "leg" and you get P. q would also work I guess if you amputated the left "leg"
Future Alien 1: My cloned humans keep dying!
Future Alien 2: Did you feed them Vitamin C?
Future Alien 1: No, why? They don’t make it? ...why were they top lifeforms?
Who said we’re top? And why should we be considered top? We build homes? Use tools? To me it’s mainly one thing, that we can pass down knowledge without having to experience it firsthand, I don’t need to touch a radioactive material to know it might kill me, I don’t need to use an electron microscope to see that it works and I don’t need to solve the math to understand why it works. THAT is what makes me think humans can be considered a top life form but even still, we lack quite a lot of useful skills
Future Alien2: when you go back to get another butt sample to make your next clone, grab a few oranges while you're there.
Why was this so entertaining?
The vitamin C contingency.
@@richardflynn4112 you're legally allowed to be a dumbass, so as long as you don't ruin the joke?
Former friend of mine went through a phase where he said if he gave up food, his stomach wouldn't get as upset when he drank all his calories. Had a change of heart when his mouth started bleeding and all his hair went curly.
Former friend?
Not enough VITAMIN C....
Gerald Nelson not enough anything
It could work... your freind was just stupid in the drinks he drank
Hehehe... DeficienC.
I'll see myself out.
Love it!
Lol I C what you did there
I'll C myself out.*
XD
@K T I think that would probably be a very good idea, especially since people think that scurvy is a joke since it's associated with pirates however a new name for the disease might change the view on it, especially since DeficienC dogs doesn't roll off the tongue as easily.
Fun fact, every year around finals week my old college used to have to put up scurvy PSAs. This is because, on SEVERAL occasions, students have gotten scurvy from neglecting to eat when studying. Higher education, y'all
I was gonna say the same thing! There were people at Uni getting scurvy cause they lived on purely ramen and red bull or something stupid like that. It's absolutely nuts how some people don't know that eating your fruits and veggies ISN'T a choice. It's a you can get sick and die if you don't thing.
Gotta love it
Recently listened to a book that covered this and similar issues called "Human Errors: A Panorama of our Glitches, from Pointless Bones to Broken Genes" by Nathan H. Lents.
sounds like a depressing book
@@mongislort6440 So is being human... frequently.
It's a pretty neat book. Not at all depressing
.
I love how in this day and age, you can say you listened to a book and nobody would bat an eye
I remember that my biochistry teacher said the same: That we lost it because we (our ancestors) kept eating fruits with vitamin c and therefore we no longer had to produce it by ourselves.
But I didn’t know that most fishes couldn’t produce it either. Does anyone know how do they get it in their enviroment?
He wasn't actually right though. You lose genes through genetic mutation that doesn't negatively impact offspring survival, not because you don't need them.
@@cookeymonster83 good point in detail, but not needing them is what makes them not negatively impact offspring survival when absent, which means mutations that happen to cause them to be absent will be passed on just fine.
In other words, what the teacher was mentioned to have said was not plain wrong but rather a simplification that may very well have been justified in its original context.
Fish food chains start from phytoplankton and and other autotrophs. They can simply get vitamin C from consuming stuff in the foodchain. Fun fact: fresh meat has vitamin C too (since animals make them or get them from food) which is why the inuit don’t get scurvy.
I hope your English has improved.
@@just4deez its mostly stored in the organs though, the meat is actually the nutritionally least valuable part of an animal.
(Had to add this for all the meatbois out there :P)
Besides scurvy, humans can also develop beriberi, rickets, pellagra, anemia...bodies are so high maintenance.
Animals can too, its just that they're better at eating proper diets
@@GeraltofRivia22 Aside from the ones that eat their own poop.
Honestly. Why do we even have them?
Flesh is weak, turn to machine
unnatural lifestyles that outran evolution and removal of natural selection am i right
Captain Cook prevented scurvy amongst his crew by feeding them sauerkraut. I can't imagine what the smell would have been like below deck.
He also fed them fresh lemons, oranges, onions and cabbage, following the advice of James Lind, a Scottish naval surgeon, who wrote, "Treatise on Scurvy" in 1753. 👍
I'm thinking that the sauerkraut probably smelled pretty nice compared to the sailors who were eating it.
To be honest, Sauerkraut doesn't even smell that bad, or that's at least how I know it
@@kevintrang3007 not the Sauerkraut. The people's farts...
My mom's husband can tell when I ate sauerkraut the day after I do so. Food comes out of your skin, but I imagine basic B.O. on a ship of sweaty unbathed sailors would be overwhelming in general.
Yay. Now we have to deal with appendixes, scurvy, and weirdly big heads to hip ratio. Thanks evolution!
Quit complaining about your girlfriend.
There’s new thinking about appendixes having a function of re-populating your gut biome after episodes of serious distress. Sort of a depository of your good gut bacteria to help jumpstart your system after say, cholera or dysentery, etc.
Don't forget the load bearing spine!
Most mammals are born with with heads and brains that are as large or nearly as large as they'll every be; humans, because of the narrower birthing canal due to walking upright, are born extremely prematurely and their heads and brains grow substantially after birth. The fact that human heads and brains grow after birth detaches any relation between hip size and head size.
Head size is REALLY inconvenient when you're trying to give birth to someone, believe me.
I’d always thought that when we got comfortable with human genetic engineering we should re-enable vitamin C production, but it sounds like that will slightly increase cancer risk, and (at least with current tech) cancer risk is a much bigger deal for most people.
I still think it would be a net benefit. Most free radicals are dealt with in short order by the bodies defenses with things like vitamin e or other compounds that make things like blueberries antioxidants.
@@TheMarshmellowLife It still more delicious to just eat those strawberry 🍓
Why is your hair monochromatic Michael. This is Highly Unusual.
I dont understand what your talking about?
@@thomasbarlow4223 For years, he's worn his hair with a light-colored stripe bleached into it.
thomas barlow mono=one chrom=color
I have friends with a natural highlight, it's not uncommon, and ranges in area. maybe that's what he has too.
@@Satan666Official No, it was just a stripe bleached into his hair... you can see it in older videos. Him styling it like that predates his UA-cam career, so it's just rare to see him without it.
Great video about an important topic! In addition to being required to synthesize collagen, (which makes up 25% of ALL the protein in our bodies), vitamin C is required to make PAM, (peptidyl alpha amidating mono-oxygenase), an enzyme required to activate CRH (corticotropin releasing hormone), growth HRH, calcitonin, gastrin, oxytocin, vasopressin, secretin, and Substance P; enables absorption of iron; and finally vitamin C is necessary to make noradrenaline. Just sayin'..... ☺
Vitamin C is also a flushing antioxidant. We should be consuming more C than we can utilize
@@herbbowler2461 Hmm. What does it flush? Because I take a lot of it and now am wondering if it is flushing out stuff that it shouldn't be. Like minerals that I need.
@@anyascelticcreations
If you mean vitamin C. It flushes out free radicals that cause cellular damage.
It is necessary to metabolize many other nutrients. Including minerals.
@@herbbowler2461 Okay, good. Thanks for the reply! 👍
@@anyascelticcreations
You're welcome.
When it comes to vitamin C. The body uses it best if you yo. yo the amount taken. High dosage for about 2 weeks followed by low dosage for about a week.
If a high dosage is taken for a prolonged period of time the body will over flush. Causing a vitamin C deficiency.
If the vitamin C does not contain bio_faviniods it can irritate the kidneys.
Good health.
Ate an orange while watching this video cause ya know
Sure wish I could have done the same...
@@VoilaTadaOfficial You still can. 😁
@@dansattah No I can't. I'm allergic to raw plants.
Had a grapefruit earlier, so I'm safe for the next few weeks.
Like really, you need a serious deficiency to develop scurvy, an orange a week is plenty to avoid it!
Edit: Totally forgot about the lemon juice I put in my water every day, actually I'm completely safe!
@@micahphilson it helps that I love oranges and mangos
Since _none_ of us have a functional GULO gene, it sounds to me like it was both the slight advantage of not having it (provided you get enough vitamin C from your diet) _and_ the lack of a disadvantage due to our ancestors’ diet.
I'm not really sure of the advantages of not having the GULO gene, but given our ancestors' diets had plenty of vitamin C, there probably wasn't any selective pressure to keep making it ourselves.
@@tristanssimpson1324 that should have just made it more of a random thing if people had it or not. In order to actively breed it out of the entire population, there had to be an evolutionary advantage to no longer produce it.
An orange a day keeps scurvy away
Or just make some enzymes
So we have a broken gene, and we know how a good gene should look like. And we have a CRISPR-Cas9 that could find a sequence and replace it with another sequence. Let's start by fixing Guinea pigs?
CRISPR doesn't work on everybody some people are immune to it
That would be pretty cool :) My first thought for the first human-oriented gene therapy for otherwise healthy people has always been disabling the myostatin genes. (People with two copies of mutated myostatin genes end up with extra muscle mass and extra strength, with no known negative effects.)
The gulo gene reduces lifespan in guinea pigs.
Your idea has already been tested.
@@Lanceolson4586 For now.... We once thought the idea od CRISPR to be only hypothetical
@@sadrien let's try birds! 🐦
My aunt is actually severely allergic to vitamin C, and she's gotten scurvy a few times. The doctors always have to administer the vitamin C really carefully so she doesn't go into anaphylaxis. She can't even so much as smell an orange without her throat swelling up.
Vitamin C is in organ meat, all types of citrus, berries and many legumes including peas. does she not eat peas or lentils or organ meats? Citrus allergies are common I am allergic to oranges for example. I do not think it is possible to be allergic to something that the body requires perhaps I am wrong but I have not found any studies that proved and allergy to something your body needs to be healthy.
@@annak804 Oh, it's possible to be allergic to lots of things your body actually needs to survive! Although it's very rare, there are documented case studies of aquagenic urticaria, or water allergy. In fact, I am allergic to all citrus, all nightshades (ie tomatoes and potatoes), all latex bearing fruits, and a bunch of green leafy veggies. I get my vitamin C from berries, watermelon, broccoli, and sweet potatoes.
Damn that sucks
@@annak804 Skin allergy
Does the Monkey have cancer on his neck? 4:25?
I thought the same thing. It didnt look symmetrical
No they have mouth pockets that they will use to hold food.
I have EDS, so most of the scurvy problems arise from the fact my body can't make good collagen in the first place, genetically.
And boy, I can get very painful....
I have a high pallet and small mouth, leading to overcrowded mouth problems, I got 12 teeth removed, 4 baby teeth, 4 adult and 4 wisdom teeth.
I got scoliosis, ripped skin, Snowy vision syndrome, joint pain, chronic pain, Barre Lieu syndrome, migraines...
Out of curiosity, what would it take to reactivate that gene artificially, and would it work properly if we did?
That's a question for an evolutionary biologist. The amount of time depends on how much money we throw at the problem (e.g. COVID vaccine, moon landing, Manhattan Project, etc.)
CRISPR and changing international law to allow us to forever cure a disease.
First we need to completely figure out DNA and genes. It could solve lots of our problems just by understanding it.
@@xephyre6955 Understanding our genes helps everyone, reactivating a gene makes an individual genetically superior to those that can't afford to
@@__--__ In this case vitamin c is or would have been usually produced in the liver it might be more available to more people than other genetic modifications (which would have to be done while the person is still an embryo) it could be as simple as introducing modified genes directly into the liver. So so so so this probably wouldn't be a problem like designer babies, could probably be done to anybody (maybe they would make it as a scurvy vaccine for developing nations).
The question is whether we should make some of these pseudogenes useful again by mutating them. The gene for gulo probably isn't worth the effort since vitamin C deficiency is easier cures by handing out some orange juice but there are others that certainly are interesting.
I'd like to produce some blasted melanin. I hate having to bathe in SPF 50 every hour outside in the summer to avoid turning into leather here in freaking Oregon. Even so, I still freckle through it. And don't give me the vitamin D defense either, because I still need to take supplements for that.
Scurvy is a huge problem in developing nations where people have trouble finding the right things to eat, also with the decline of the bees fruit production will decline as well so vitamin c might become harder to get in the future, maybe it would be worth looking into this now so that when these inevitable fruit shortages arrive humanity will be prepared to deal with it.
Now I want a video about the convergent evolution of the other animals that also don't make vitamin C
I would make a pirate joke but I'm afraid pirating is illegal.
I guess Limey jokes were deemed to have a higher probability of offense and were sent down the plank.
ua-cam.com/video/Vn9BeN8NBaA/v-deo.html
"Anything about booty is a good time."
-Michael Aranda
I wonder if not synthesizing a vitamin you have plenty of in your diet can make your metabolism more efficient.
Also, Michael sounds very mysterious today.
There are research papers on this subject.....
@@dwwolf4636 Phew, that's a relief!
Probably, although it's probably not much of a benefit compared to the drawback of not having vitamin c at all.
The way I was brought up, I couldn't even imagine, humans could live without fruit and vegetables. But scurvy in a developed country seems to indicate that people actively avoid fresh foods. Vitamin C is the most readily available vitamin in natural foods after all...
Or it's an indication that nutrient-rich foods have something affecting their availability to certain portions of the population. So we look at the groups which are most affected by this and oh hey it's the poor. Being poor makes optimal nutrition more difficult, from the dearth of cheap-yet-nutritious options - as well as the time/expertise to properly utilize them - to the plethora of easily prepared, energy-rich but nutrient-poor alternatives stocking most American shelves. Add in the fact that the latter are formulated to have textures and mouth feels optimized for dopamine production, and it becomes a lot less "people are avoiding fresh foods" and a lot more "people without reasonable alternatives are having highly addictive substances in food form pushed upon them from birth."
What I learned from this video: The fruit of the naturally grown bike tire is a good source of vitamin C.
I just finished a big ol plate of steamed bike tire.
It would be interesting to gene edit some other primates to correct the mutation to see if there were any downsides of being able to produce vitamin C.
It’s probably just that it happened to mutate and we had enough sources of vitamin C externally so it faded away from the gene pool bc it’s a needless use of energy if it’s already there
@@quentinh5566 Yes, I think some other animals (Guinea pigs?) have a different mutation that prevents them producing vitamin C.
When someone says scurvy, I do imagine pirates, however I do not think of a joke.
Your voice is so calming! Does anyone know if he hosts anything else? :-)
I am a follower of the "ehh, good enough" theory of Evolution.
Sometimes you lose a trait, sometimes you gain a trait... happens.
Not a fan of that one since I strive for perfection in every conceivable way.
and suddenly, i have an overwhelming urge to eat oranges >_>
Michael's voice is so soothing this video, I could go right to sleep
Great to see you again Micheal, looks like you got your vitamins.
I’m about to go to the CEO of Scurvy and spit some straight facts at him about what he’s supporting
I used to see you everywhere.
pizza hut seemed convinced at some point this year that one could prevent the spread of scurvy by washing one's hands, as per a handwashing graphic which was posted also claiming one could prevent the spread of hangovers.....
Have you ever caught a hangover from someone who washed their hands? No? See, proof
Orange you glad for vitamin C
😑
Sure am. *jams out to Vacation*
That pun was a lemon ;)
hydrogen peroxide, although not a free radical, is a reactive oxygen species in of itself. Contrary to popular belief, it is not the biochemical sources of ROS that are problematic but a disruption of its finely regulated homeostasis by stress factors. However, the stress can be considered a signal and the ROS imbalance is a biological signaling method cascading downstream. Furthermore, ascorbic acid (vit C) is a nonenzymatic ROS scavenger, which in the worst case scenario could theoretically reverse the oxidative damages caused by the H2O2 produced from the production of vit C
So could the functional gene be reintroduced via CRISPR or the like, thus eliminating scurvy all together?
Hang on, let me get my chemistry set.
I don't know. The part about rabbits and goats regulating their GULO output makes me think other genes are involved, and trying to find and fix *all* of them... So without the regulatory framework, maybe you'd end up with way too much or way too little, or maybe your body would be *able* to synthesize vitamin C, but would never actually produce any.
Even if that is something that could work it would be pretty hard to do it for everyone.
@@fireriffs that's why I eBay has a do-it-yourself kit. It's kind of pricey but it's gotten some pretty good reviews.
Maybe. But the CRISPR is still at an early stage considering its interference on ethics.
I think it's fun that pine needle tea is a great source of vitamin C. (Some types of pine tree are better for consumption than others.)
Literally every sailor in history:
Damnit Joe you had one job!
Someone should use CRSPR to fix this defect.
I'm surprised losing the Gulo Gene was a random mutation and not necessary sacrifice in order to grow a bigger brain and hands to use tools.
bro i think you got the evolution part a little bit wrong.....EVERY mutation or change in the history of life since its creation has always been random. Cell or genes are not conscious in a sense that they can plan a mutation or think like "okay lets see what happens if we alter this gene and if doesnt work we simply reverse it". In reality mutantions are random and if the particular mutation gives some advantage to that individual from other individuals of his species then the likelihood of survival that individual increases and therefore that gene has more chance to get passed down and over time the population of the gene carrying that mutation is what remains.
@@harishsingh5491 Never thought Cells and Genes were conscious. I was thinking about change and adaptation overtime. There are people that can't eat certain foods because of they aren't used to that type of food. Even if this isn't the best example, It doesn't mean that Cells and Genes being conscious is implied. But I do understand why you commented. "Necessary" was the wrong word to say. My bad.
@@afrikasmith1049 yeah you are spot on, that "necessary" was the reason i wrote that just to convey that their is no plan or purpose in mutations, they are just simply random. I just framed it in a wrong way. It is my bad too, i should have written "As you know cells and genes are not conscious......".
@@harishsingh5491 NP.
favorite joke from Rocky and Bullwinkle was a doctor examining pirates and says to one "You've got scurvy son, get off the ship and eat some oranges."
Michael about evolution: "it be like that sometimes"
I love Michael Arranda. He’s sweet and funny and handsome and goofy and clever.
Thank you for using "whom" properly. Great content. I love SciShow!
Whom was that?😁
Time for scishow to upload their yearly video on scurvy
The "ascorbic" in ascorbic acid (vitamin C) actually means "anti-scurvy".
Very interesting. That good video. !!!
Would you narrate an audio book? Your voice is very soothing.😍😊
I freaked out at the beginning thinking Michael cut his luxurious locks but I realized this video was 2 years
Really, nothing should depend on something called "GULO."
Free radicals are NOT just free floating electrons. They include the naked proton and the OH- radical, just for starters. Some of these free radicals, especially in the case of radiation, can also be thermally energetic (hot) which can cause further cellular damage.
Pioneers use to drink Pine Needle Tea to fight off Scurvy. It actually has multiple times the daily allowance.
Human player's inability to produce vitamin C is no less than a balance patch, they're pretty OP as it is
Zootier xD
Am I on a higher difficulty then? I'm allergic to citrus.
I once cut vit c out of my diet to improve the effectiveness of a certain medication and before long I has tender, sore gums and pain in my knees and shoulders(I was 20 y/o).
Like the Man said:"We ALL NEED VITAMIN C !!
@@geraldnelson2234 have you never been 20? I thought I was invincible
I can't imagine that the scurvy tag has been used much on UA-cam
Even nature hates pirates...
Free radicals are not necessairily electrons, but the molecules have at least 1 half electron pair. nice vid tho.
How do inuit and other northern/isolated people avoid scurvy?
Depends how northern. Lots of evergreens have very high vitamin C content in their needles, so spruce trees are a major source. Failing that, they can eat animals which produce their own.
Fish get it from plants and people eat fish.
Lots of fermented foods develop C in the rotting process. Rotten fish head soup is a thing in Alaska.
Ada Soto Rotten fish head soup? That can't be better than dieing.
@@Primalxbeast Guy in my dorm in college would get in fights with his grandmother about the need to eat it since they could now get orange juice at the store.
A friend of mine had scurvy for a bit. He ate 2 things ever : frozen chicken nuggets and lemons. He liked the lemons cuz they tingled. Doctor says to stop eating it because hes allergic and eat different things, but he stayed with eating only chicken nuggets. Then he goes to the doctor cuz hes bleeding a lot and he feels bad all the time and he keeps getting cuts.
"Any thing about booty is a good time"-
"And if you wanna experience some of that for yourself"
I honestly thought we were getting a Sci Show hookup app.
I wonder if that's why some people can handle an all meat diet without getting scurvy, they are getting the collagen directly without needing to rely on a vitamin to chemically build it? It's undoubtedly more complicated than that but I'm curious if anyone has looked into it?
There are some meat products that contain Vitamin C, like certain whale parts, which is a large part of how some Arctic peoples like the Inuit (Eskimo) have traditionally gotten by. I'm no expert and agree that it's interesting to look into. I'm sure there are research papers out there.
Scurvy: *is mentioned*
College students who haven’t eaten an vegetable in three months: *have entered the chat*
Edit: Guys, the an is supposed to be comedic, and stop talking about stereotypes, I say “college students that haven’t eaten a vegetable in three months” not “college students” because I know not all college students are stupid. I’m not talking about people who can’t afford vegetable either, I’m literally making a joke about people who chose not to eat fruits or vegetables. Stop arguing
It's a not an. Students these days.
ha! Ha! Get it? College students are poor & have problems!
Most sources of vitamin C are fruits. A lot esier to convince someone to have some watermelon than it is spinach.
They may yet survive.
@@safir2241 Lettuce and carrots are cheaper than big macs, weed and alcohol.
xenophanes
Except your dumb ass stereotype about college students smoking weed & is just that. Ever heard of the triangle? Education, social life, health. Choose one.
We got scurvy we need some Vitamin C
We got scurvy we need a lemon tree
You need a presenter named Robert. Then we can call him SciShow Bob :-)
What about people with allergies to citrus? Do they often run into something like scurvy, and what are the common supplements they take to correct or prevent that?
I want a hour long compilation of Michael just talking, he's dreamy ❤
The thing that scares me about scurvy is that old scars open again
"Anything about booty is a good time." Now that's what I'm talking about!
Scurvy also leads to any and all scar tissue breaking down, which leads to every wound you've recieved in your entire life re-opening and every bone you've ever broken re-breaking.
I just noticed his awesome triangle freckles.
Aren't anybody gonna talk how cute the baby is at 1:16 😍😍😍
Ben Bova made a point of in "Mars", when the Mars mission nearly failed because a meteor strike destroyed most of their vitamin supplies and nobody noticed until nearly too late. None of the scientists had scurvy on their radar :)
I was familiar with the clinical presentation of scurvy, but the idea why the gene got turned off is very interesting.
Hey, the whole cat family can't taste "sweet" because of a DNA mutation that occurred before the LCA of all modern cats. =D
And pandas can't taste umami or "meatiness" as the gene for that is broken in them.
And snakes are literally deaf because they have no external auditive system.
My cat loves salty tortilla chips, salty crackers...anything salty!
Burn Angel they are not deaf, they do have hearing that is less sensitive then humans however
FUN FACT: Traditional Lacto-Fermentation of cabbage (as in sauerkraut made without accelerators such as vinegar) increases the vitamin c by a factor of 7! So it takes it from 100 mg per cup to about 700 mg.
I like how they said developing nations and then the USA like there’s supposed to be a difference. No universal health care you’re basically a second world country lmao.
With the amount of homeless and starving people the US has it's actually more in need than a lot of developing nations.
Yes, it's more difficult to survive here than many people in other countries think. There is a ton of poverty and illness here. It's just not what is shown in the media.
As someone who has been sick for most of my life and is unable to afford healthcare or to work outside the home, I am very familiar with that.
I have also seen bits of what it's like for the homeless here.
The lives of a lot of people are not very first world here.
Alright manchild, back to Reddit.
@@cookeymonster83 Probably shouldn’t be taking in so many immigrants then
@@anyascelticcreations You ever seen what homelessness is like outside of a first world country, hun?
I like this speed of talk.
Funny how people typically think of citrus fruits, while they aren't even the winners in tems of Vitamin C content...Well played with the thumbnail there, SciShow ;)
Citrus fruits are still a good example though. Most people can easily find an orange and are likely to be willing eat it. So yeah they may not be the vitamin C winners but it's something that we can probably get into your diet simply and quickly. It doesn't matter how good a food is for you if you just won't eat it for some odd reason!
r/iamverysmart
That and vitamin C is in and out of your system in a day.
Biomed Master gooooo jalapeños!
Biomed Master Funny enough, citrus actually got its reputation for being high in vitamin C because, when it was discovered why sailors were getting this strange sickness called Scurvy, those seamen would haul crates of oranges and lemons with them because they lasted a long time at sea without rotting or over ripening.
So while, yeah, it’s not the most “efficient” way to get vitamin C, it was the most practical for shipping crews.
I think the non functioning gulo gene was past down because our distance ancestors were around lots of vitamin c rich foods so it didn't matter. Now if they were in a environment with no or very little vitamin c fod sources this mutation would of been a deadly.
Growing up in a developing country myself, i never knew scurvy was actually rare in developed nations. I thought everyone got scurvy once or twice every year
It depends on where you actually are I guess. As someone living in a developing country myself, albeit a tropical one, I've never heard about scurvy until I read about it online.
Many modern processed foods are actually fortified with vitamin c, of course not all of them are or can be but that makes it significantly harder to get scurvy, of course not all of them are so it is still possible it's just more difficult. Honestly with how badly people eat nowadays this is definitely a good thing, I imagine scurvy with me much more well known in developed countries if this wasn't done.
Note: vitamin c is also called ascorbic acid, so if you see that on the ingredients list then you know that that food has been fortified with Vitamin C
It's not uncommon among cruise ship crew members either
Not one joke about how the British (sailors) are sometimes referred to as "limes".
By Americans. Who, contrary to their own arrogance, don't represent the whole world.
"Whatever happened to Richmond?"
"He got scurvy."
It takes too much energy to make vitamin C, and it’s abundant in nature. We use that energy for everything else.
A pirate's favorite disease. Do what you want cause a pirate is free, you are a pirate!
My name is avery
Yar har fiddle-dee-dee, scurvy's your absolute favourite disease! Don't eat your fruit when you're sailing the seas - you are a pirate!
@@haferman92
Avery Richman?
I know someone who got it not to long ago. Really messed him up bad. Months in the hospital.
Some other fun little mutations include: No fangs, no claws, no wings and no body armour. Humans, basically spam wearing shoes. 🤔
Yet we have such big brains that we can craft better versions of everything you mentioned.
Knives, metal claws, airplanes, and armor.
I think that's cooler.
@@Burn_Angel well yeah, but from an evolutionary perspective it would be awesome if humans weren't so squishy, helpless offspring, vulnerable females, prone to diseases, extremely slow to mature, not enough body hair to protect you from the elements (but just enough to be considered unsightly) but you're right our ability to turn a stick into a club was the game changer, but all we appear to have as a tactical natural advantage is melanin skin pigmentation 🤔
@@OpEditorial You're underestimating humans. We have a much higher resistance to diseases than you might think, mostly when we have the best food we can produce, as we need plants and livestock to be the best food sources they can be, and if you combine that with our cooking skills, you get a lot of nutrition, which while it doesn't make us invincible, it does raise our defenses quite a bit. Being omnivore adds a lot to that.
Also, having almost no body hair is actually one of our best traits. Humans are the creatures best adapted to long distance run in the world, and having no body hair allow us to cool off faster AND it lets our sweat spread easier, cooling us off even more.
And while our upstanding posture help us to run better, its main addition to us is balance, which in turn made our skill to throw stuff more precise and strong. And when you're throwing pointy sticks, that's deadly to anything, no matter if you're an oversized sloth or a big hairy elephant.
I recommend you to watch TierZoo, in his video about humans, he explains my points in better detail, and you might fall in love with his...format.
@@Burn_Angel well yeah, but it would still be cool to have at least one of the adaptations the animals (we're currently driving to extinction) have, retractable claws are awesome 🤔
@@OpEditorial Well, at least we can do stuff like seeing in colours, or being able to taste sweet stuff. Dogs and cats have none of that (respectively).
And we live enough for our intelligence to build up a lo of knowledge, unlike octopuses.
And we have hands that allow us to use tools, which would be possible for a lot of smart animals like pigs, but unfortunatedly they can't.
And again with tools, we can use shovels to excavate and hunt down prey that hide in burrows, which would be awesome for animals like coyotes.
We are really awesome in our own way, don't forget who's on top of the food chain c:
I adopted a Guinea pig who had scurvy. He had been neglected and never had fresh food. He survived for 3mo after I got him. He was scaly with hair loss. The companion he was surrendered with passed less than 24hrs after. Elvys looked a bit like a goblin when I got him. Made sure he had a good life, even had a gf, though they weren't allowed to even try to make any babies
Number 69. Aaaaalllll riiiiiiight.
😌🍌👄🍑