N linked glycosylation | What is the role of N-linked glycosylation in ER protein folding?

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  • Опубліковано 20 вер 2024
  • This video describes the concept of N linked glycosylation and its utility in details.
    It talks about the following questions:-
    What is the N-linked glycosylation?
    What are the three types of N-linked glycans?
    What amino acid is used specifically in N-linked glycosylation?
    What is the role of N-linked glycosylation in ER protein folding?
    cell biology # organelles

КОМЕНТАРІ • 103

  • @linelund2309
    @linelund2309 5 років тому +19

    Thank you sir! Great work :)

  • @anusha4975
    @anusha4975 Рік тому +16

    I hope you get everything you want in life

  • @kathlapointe7283
    @kathlapointe7283 4 роки тому +5

    Thank you ! Because of you, I understand better the N link glycosylation. Thanks for animated video, it helps understanding better. I hope to have an A+, thanks !

  • @bcmorrison3
    @bcmorrison3 6 місяців тому +1

    Thank you arpan for putting together this very helpful video.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  6 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @Shells12-v5c
    @Shells12-v5c Рік тому +2

    Thank you.. you made this easy to understand..

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

  • @eastofthegreenline3324
    @eastofthegreenline3324 2 роки тому +1

    Very nicely done. Enjoyed watching this!

  • @daliairaisgarciacastro4858
    @daliairaisgarciacastro4858 3 роки тому +4

    Thank you so much for this video! I just have a question, can you tell me how is the glycosilation process or product different in yeast? I'm studying a lot right now to make my thesis, and your explanations help me get a deeper understanding of this process

  • @dennisjecool
    @dennisjecool 3 місяці тому +1

    Thanks man, really helped!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 місяці тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @bcmorrison3
    @bcmorrison3 4 місяці тому +1

    We have a need to animate the upregulation of DPAGT1 gene and subsequent over-expression of UDP-N acetylglucosamine-dolichyl-phosphate acetylglucosamaninephosphotransferese 1 which activates solid tumor cancer growth and metastasis pathways. Would you accept a fee for service? It’s for a multi-university team and would aid cancer therapeutic development.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 місяці тому

      email us , we provide low cost quick services ( within 48hrs). contact email: arpanparichaa1994@gmail.com

  • @AmruMagdy
    @AmruMagdy 5 місяців тому +1

    Nice lecture sir..

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @thrivegoodlifecoach1074
    @thrivegoodlifecoach1074 2 роки тому +1

    My son has been diagnosed with i-cell, after 15 years misdiagnosed CP. The Dr has prescribed a.ong other things an Antiglycosylation, what does this do in plain English.

  • @JMSouchak
    @JMSouchak 4 роки тому

    Excellent video, thank you so much for teaching us!

  • @shahtajmir9273
    @shahtajmir9273 3 роки тому +1

    Good job
    Keep it up!!!!!
    Thankyou

  • @katp9116
    @katp9116 5 років тому +4

    This was great! I looked through your videos and I didn’t see the O linked glycosylation video you said you’d make. Did you make it?

  • @cartikey3743
    @cartikey3743 Рік тому

    Why sugar Moieties are activated?

  • @vanniarkaranshanmugam757
    @vanniarkaranshanmugam757 5 років тому +2

    Great work!!!

  • @ricman223
    @ricman223 2 роки тому +1

    so helpful i thank you so much!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому +1

      Please share my channel link with your friends and help me to reach big audience

  • @markusbrentarevalo5725
    @markusbrentarevalo5725 4 роки тому +1

    Hi sir nice video!!! May I suggest you to discuss glycoprotein homeostasis network which was made possible by N-linked glycans that is very much related to this video. Thankyouu!

  • @theconqueror8579
    @theconqueror8579 4 роки тому

    i am preparing for iit jam and tifr and these videos are really helping me with getting concepts in very easy way thanku so much for these videos . There is one request can u make some videos for maths too..

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 роки тому

      ua-cam.com/channels/JvSHjOoL2FDN85hQbu7vfw.html follow this channel for physics part and maths

  • @smittywerbenjagermanjensen9281
    @smittywerbenjagermanjensen9281 2 роки тому

    thx so much this stuff is so cool (:

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @Ben-dv8xw
    @Ben-dv8xw 3 роки тому +1

    Thank you this is great

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 роки тому

      Please share my channel link with your friends and help me to reach out to big audience.

  • @pawanrohilla01
    @pawanrohilla01 5 років тому +2

    Great video Sir.
    Please make more videos upon Biochemistry.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 років тому

      Specifically suggest some topics

    • @pawanrohilla01
      @pawanrohilla01 5 років тому

      @@animatedbiologywitharpan
      TCA cycle, oxidative phosphorylation.

    • @pawanrohilla01
      @pawanrohilla01 5 років тому

      @@animatedbiologywitharpan
      And some basics of biochemistry like Proteins, carbohydrates, Nucleic acids etc

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 років тому +1

      @@pawanrohilla01 ya it would be uploadeduploaded
      Soon

    • @pawanrohilla01
      @pawanrohilla01 5 років тому

      @@animatedbiologywitharpan
      Thank you so much

  • @ananyapramanik5714
    @ananyapramanik5714 2 роки тому +1

    Thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 роки тому

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on Instagram as @animatedbiologywitharpan. Install the app to follow my photos and videos. instagram.com/invites/contact/?i=1p41h314q3fv8&Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @vedanshipal1308
    @vedanshipal1308 3 роки тому +1

    Thank you so much sir!

  • @raktimchowdhury7127
    @raktimchowdhury7127 4 роки тому +1

    So, once this N-linked glycosylation is finished, then this peptide tagged molecule goes to the plasma membrane and settle there? So I just want to know Is the same structure of plasma membrane glycoprotein?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 роки тому +2

      Glad that you took your time to comment.
      What I can tell you is several plasma membrane proteins are N-glycosylated on their extracellular domain in the endoplasmic reticulum and further glycosylated in the Golgi before transport to the cell surface.(apart from plasma membrane proteins several enzymes are also N linked glycosylated). This carbohydrate tree on membrane protein could affect its folding, stability, trafficking to the cell surface, and/or function. The occurrence of carbohydrate-deficient membrane glycoprotein leads to a syndrome I-IV disorder in humans, which can be life-threatening, indicating the fact that proper glycosylation of both membrane and secretory glycoproteins are essential for development and disease.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 роки тому +1

      if you like my explanations please share among your friends and help me to reach a big audience.

  • @Mar-eg3lk
    @Mar-eg3lk 3 роки тому +1

    awesome video thanks : )

  • @smritikanapaul6379
    @smritikanapaul6379 4 роки тому

    Very helpful video.thank u

  • @Bev0946
    @Bev0946 Рік тому +1

    thank you sooooo much!!!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Рік тому

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

  • @kor_cinnamon
    @kor_cinnamon 3 роки тому +1

    Thank you very much

  • @theclassroomdoc
    @theclassroomdoc 4 роки тому +1

    Thanks super video!!!

  • @kantnesragnarok6128
    @kantnesragnarok6128 5 років тому +1

    nice dude really nice .

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 років тому

      Kantnes Ragnarok positive response of you guys is my motivation...don’t forget to check out other videos in my channel.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 років тому +1

      Kantnes Ragnarok please share among your friends group and help me to reach big audience

    • @kantnesragnarok6128
      @kantnesragnarok6128 5 років тому +1

      yeah

  • @shankarpatil8267
    @shankarpatil8267 5 років тому +3

    nice sir

  • @rokayaahmad7617
    @rokayaahmad7617 3 роки тому +1

    thank you a lot

  • @willgazlay5711
    @willgazlay5711 5 років тому +1

    Could I get a copy of these slides? Some of these figures would be extremely helpful for me to study :)

  • @khansajamil21
    @khansajamil21 3 роки тому +1

    Excellent presentation. Can I have this pptx.

  • @الحمدلله-ع4ي2ق
    @الحمدلله-ع4ي2ق 4 роки тому +1

    Nice sir

  • @kajolkumari5621
    @kajolkumari5621 3 роки тому +1

    Too good😊

  • @laureprx5560
    @laureprx5560 5 років тому

    Thanks a lot !

  • @hajiraaasyed
    @hajiraaasyed 4 роки тому +1

    I have mailed you sir. Could I please get a copy of these slides. It would help me to study. Please.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 роки тому +1

      Sure.....please share among your friends and help them as well

    • @hajiraaasyed
      @hajiraaasyed 4 роки тому

      @@animatedbiologywitharpan Sure sir. Thank you so much.

  • @aprilhicks3474
    @aprilhicks3474 3 роки тому +1

    sweet!

  • @prabhrit
    @prabhrit 4 роки тому +2

    Too much ...thanks sir

  • @朱康乐-n9o
    @朱康乐-n9o 4 роки тому +1

    Can I get your lesson‘s ppt?

  • @chemssoubessebaa6574
    @chemssoubessebaa6574 5 років тому +2

    a copy of these slides please

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 років тому

      Chemssou Bessebàa I would send you shortly

    • @chemssoubessebaa6574
      @chemssoubessebaa6574 5 років тому

      i already sent u a message on gmail , chek the box

    • @pinkycarmona2436
      @pinkycarmona2436 5 років тому

      Hi! Great work! Can I also ask for a copy of these slides and those of O glycosylation also? Very helpful!

  • @kelp9517
    @kelp9517 9 місяців тому +2

    concepts like these make me hate biology

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  9 місяців тому

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

    • @kelp9517
      @kelp9517 9 місяців тому

      @@animatedbiologywitharpan i will share this :), this is a great video btw

  • @الحمدلله-ع4ي2ق
    @الحمدلله-ع4ي2ق 4 роки тому +1

    Nice sir