Discover How Methylene Blue Impacts Your Microbiome
Вставка
- Опубліковано 8 лис 2023
- 🧠 In today’s video Dr. Dane Newville will discuss the impact of Methylene Blue on the bacteria in our gi tract, also known as our microbiome.
In this video, we'll be discussing the effects of methylene blue on the microbiome. We'll be discussing its benefits and how it can be used to improve your health.
Methylene blue is a medication that has been used for many years to treat various conditions. It is also known to have a positive effect on the microbiome, which is the collection of bacteria and other microorganisms that live in your body. In this video, we'll be discussing the effects of methylene blue on the microbiome and how you can use it to improve your health.
📽️ To view Dr. Newville’s 1st video on Methylene Blue: • Methylene Blue: The Ul...
📋 Schedule an APPOINTMENT with a Licensed Pharmacist: mdcustomrx.com/request-appt/
📝 Sign up for our email newsletter to receive exclusive offers, notifications of upcoming seminars and special events: mdcustomrx.com/newsletter-sig...
The information presented in the following video are based upon the experience and training of the presenter and scientific information currently available. The suggestions in this presentation are not meant to be a substitute for medical evaluation and treatment. The presenter does not recommend changing or adding medications or supplements without consulting your personal physician.
The presenter specifically disclaims any liability arising directly or indirectly from the use of this presentation.
This video is NOT sponsored. Some product links are affiliate links which means if you buy something we'll receive a small commission. Before you make any changes in your health regimen or diet first consult a physician and obtain a medical exam and proper diagnosis. Seek the advice from a physician or other qualified health provider regarding any medical condition questions.
💝 THANK YOU FOR WATCHING, COMMENTING, SUBSCRIBING & LIKING. Let us know if you have any pharmacy health questions in the comment section below the video. One of the goals of this channel is help educate you in simplified terms so YOU can easily optimize your health.
CONTACT INFO: MD Custom RX
☎️Ph # 262-373-1050
🕰️ Hours: 9:30am-6pm CST M-F
📧 Email: brookfield@mdcustomrxsecure.com
Kudos to you Dane, for stepping outside the box. I'm a 30 year pharmacist who operates a hyperbaric oxygen facility. Love MB, HBOT, red light tx, etc. So many safe and effective alternatives to many medicinals once you start looking. Keep up the good work!
Thanks for sharing!
I have complex ptsd and MB stopped my inflammation that had me bed ridden in 5 days
Very useful information. I also suffer from CPTSD and have a lot of inflammation as the result of severe freeze response and all
I started taking MB a week ago, daily, starting with a couple drops and bumping up progressively. Currently at 4-6 drops a day in the morning. Will probably stay there. Already I've noticed a significant reduction in fatigue. But I also take Agarikon, Lions Mane, B-complex, Zinc, D3, and Turkey Tail supplements simultaneously. But it wasn't until i started MB that i noticed a difference.
Hello! I am curious how are you doing now. Any bad reaction?
@@lu139can2 Nope. I’ve been on a week rest period just to see if there is any change. The fatigue has increased a little again but otherwise normal and had no adverse reactions when taking them. I’ll probably start back up on Monday with a daily single dose regiment of each.
Just started a one drop dose of mb. Loving it so far! Helps with my Lyme symptoms & has renewed my strength & mental sharpness. Even seems to have boosted testosterone a bit, but can't confirm. Just feel more solid, strong and confident.
@@RA82828 Works for me. When I miss my drop, I don't have the same vascularity. As soon as I take it, within an hour, bam, veins popping
I also have chronic Lyme, going to try it
@@contagiousintelligence5007 I moved up to 4 drops. Better results. Doesn't get rid of Lyme by any means but did help with endurance to get through the day
When I started using Methylene Blue (about 9 drops per day) I got dizzy and light-headed, but I continued taking it because I was suffering from brain-fog and arthritis. After a week of taking it, my dizziness and light-headedness went away.
and how is your arthritis and brain fog?
Did it help your arthritis?
do you take boswellia along with glucosamine? i find those 2 along with omega 3 work amazing to stop arthritis pain@@Joe_C.
Arthritis stay?
@@Joe_C.hace you tried the carnivore diet? that should help with arthritis
I had a severe case of fungus on my leg and nothing was knocking it out. I took MB for a week and it dried right up. I did have a reaction to taking it but it was worth it.
Did you ingest it only? How much did you take?
What type of reaction if you don’t mind elaborating?
Yeah. What kind of reaction did you have??
Yes! Would love to hear more please!
Thanks for being so detailed
I learned to take MB, first thing in the morning and then do not eat or consume anything else for at least three hours afterwards which I guess allows it to circulate through your body and perform its function. thus far, I found this to be a superior protocol, I think I’m really loving methylene blue
How is it with dizziness
@@Helloswee If you’re asking, whether I got dizzy the answer is no there was no issue with dizziness
Appreciate your comment. Would you mind sharing what brand and dosage you take? Also, is dosage dependent upon body weight? Thank you!'
I have been using MB for over a year. 5 to 10 drops a day. No negative effects noted.
Thinking about starting. What benefits have you noticed if any? Thanks
@@MrTrda, at 69 I am in better overall health than I have been in years. My skin has improved. Better lung function (tested), lower PSA, my mind is clearer. I am taking only Losartan for BP, Metformin and Ozempic for pre-diabetes. I also take several supplements. Nattokinase, Serrapeptase, Lumbrokinase, Bromelian, Benfotiamine, NAC, CoQ10, Omega 3 (2000mg/day). Plus a few “normal” vitamins.
@@MrTrda I’m a 60 yo F , 115 pounds, and I take 6 mg when I wake up.. It is kind of like a shot of espresso to me. I’ve forgotten to drink my coffee until later in the morning because it gives me so much energy. I have fam history of Alzheimer’s and that’s why I’m taking it. I’ve been on it for about 6 months. No side effects except green urine when the MB mixes w my B complex vitamin !
@@leighnapier4505 thank you, nice get feedback on these things, I’m still on the fence…. I will do some more research. Glad to hear it has been helpful : )
*for the Alz’ that runs in your family…. I would highly recommend looking into the elimination diet starting with anything highly processed breads/snacks/sugary drinks etc. I am currently on a strict carnivore diet and have never been happier. I plan on reintroducing small amounts of organic fruits, nuts and some vegetables to see how I do on them. Also, intermittent and scheduled long fasts. Alzheimer’s is disease of the modern diet, we can be genetically predisposed to it, but we are not genetically destined for it 💪
@@leighnapier4505 No green or blue urine for me at all, yet. Started 3 days ago with 10 1% drops, and yesterday I did 16 drops, and still nothing. But b-vits always turns my urine yellow (and not taken any at this time, I have some rare experiments with them, as I don't think they do much, aside from b12 to ensure it's not getting low). But it is effective indeed! I had the beginnings of a cold or something, and I really felt it working in my sinuses, I've also felt the itchiness that you feel when wounds are healing in places in my body where I've experienced mild pain, like a tooth. So I think it's the first substance I've taken that really speeds up my healing.
This could be amazing for me, and for so many others! Well, it already is amazing, but it could also help make other self-development stuff easier and more effective, I think. My reading and typing is already faster for one.
Maybe it's because I take NAC in and around when I dose MB. As vit-c does reduce MB, and maybe NAC has that same effect. Though when taken in the same water, I can't really detect any reduction, maybe I should have them react in a greater concentration so I can see if it does reduce it (turn it colorless).
The blue seems to have been the solution for my long term undiagnosed illness. The first couple of days exacerbated my existing symptoms and then they went away. I’m not on a strict dosing schedule it varies. Average is 15-20 mg/ day I’m about 70kg.
I’m curious your symptoms docs aren’t trained in healing or tissue mineral analysis work which I’ve got some training in I can likely help get you info your mystery illness is likely a simple stuck imbalance of minerals with one thing too high or low trapping something else in a high/low pattern
These temporary side effects may be a form of the, 'Jarisch-Herxheimer Reaction!
(You feel worse before you get better!) i.e. "A good thing", as Martha says.
candida/bacterial overgrowth die off symptoms
20 mg is 40 drops of 1% solution?
@@adelyawnusually 0.5mg per drop
01:53 Russian Study
03:20 Microbiome -
05:20 MB is non discriminatory
05:45 MB's Cognitive correlation
06:30 Results of
15mg/kg: Increased cognition, no change in microbiome
vrs 50mg/kg: No change in cognition and a marked change in microbiome
07:45 Mice Vrs Humans
08:20 Study take-aways
09:35 Everyone's enzymes are individual plus Standard Dosing vrs Study Dosing
12:25 Context and his view
My view: We are so far below the dosing they are talking about that I think we can be assured this is not having a long-term negative impact on our gut microbiome.
ALSO I am challenged that this pharmacist is using much higher doses than we are, generally, with few issues.
Food additives such as emulsifiers etc are thought to be detrimental to gut microbiome. There are foods and supplements that can also help with microbiome.
Thank you! Very helpful
What’s your dose and how often? I’ve read so many different opinions I feel lost lol. 🙏🏻
I use 0.8 mg (two drops) and I still see great benefits. It stops my jaw, tooth paın controls headaches , great for sore throat or cold/flu. I thınk less is more with MB.
I wonder if they are able to dose so high because they are administering MB intravenously. 15mg/kg orally sounds like it would be hard to tolerate orally
Feeding gut flora is important. A great way to do that is with freshly picked vegetables & fruits, especially with the skin. Foraging is superior. Organic store bought types are now coated with toxic Apeel &/or Edipeel. They no longer taste the same.
I recently went out if town 2 1/2 weeks, leaving a container of spinach in my fridge. It still looked fresh when i returned. It went on my compost.
Ive also noticed lemons no longer taste right. So glad I got a dozen new trees last year.
I shop at a natural food store that refuses any produce with Apeel
I grow alot of my own food too.
In winter I grow kale, lettuce, and strawberries inside under lights .
Keeps me going thru winter with some fresh stuff🤩
Be careful eating this if you have SIBO, or gastroporesis
@@tammyrobinson1613I had SIBO and this was the only diet I could eat to stay well
@themothers they say to not eat fiber, which I found to be true. This just created more pre-biotics; gas; Diarrhea, etc.
The only diet tgat helped me was GAPs.
But, Being homeless it's not easy this type of food.
And with gastroporesis, you have to be careful of fiber, whether you have a feeding tube, or not
@@cheesecakefan4880what is apeel? Never heard about it.
Thank you so much for putting this research based content out there
Very much appreciated your content in all ways
Sublingually is definitely the better oral method. I’ve heard IV was the best. The one thing I don’t like about studies, especially regarding the Microbiome is that light affects the Microbiome, and in all of the studies they never control for the lighting in the laboratory. All of the lighting in the laboratory is usually crappy fluorescent lights. Take methylene blue outside under The sun, and it might not be an issue
Most informative.Thanks.
So nice of you
Thank you for this pearl.
ive been dosing methylene blue at 5 drops .7mg per drop per day so about 3.5mg daily, for about 4 weeks now. Even at a low dose, I've noticed it has greatly effected my brain fog caused by chronic Lyme disease. My clarity and focus feels like I've returned to baseline after 7 years of feeling cognitively impaired. However I will note there has been a notice in gastrointestinal changes, less consistent BMs and much more flatulence. I only have access to the digestible liquid form from health natura LLC, but I'm going to start taking it sublingual and see if theres any change in the gastro issues. will absorbing MB sublingually prevent any gastro issues l? my thought that if it just goes straight to the bloodstream it shouldnt affect gut biome as much.
Likely will stain your teeth blue if used regularly. Likely will not affect your guts as much if taken at the same time as a vitamin C drink like strawberry juice. It has helped me to drink it with cider and orange juice.
Edit: after longer regular use, I get less gastro intestinal problems drinking it diluded in water or mango juice. I also do not see the blue again next day. If I take vitamin C with it, I usually pass the blue same or next day.
Taking it in water or mango juice prevents pissing blue.
Doesn’t stain teeth - easily brushes off, unless perhaps you have plaque on your teeth
Vitamin C might inactivate methylene blue.
It's likely provoking bad microbes in your gut , I personally would not worry about it
@@drironmom6815your correct Vit C will interact with MB and should not be taken at same time. MB should be taken first thing in morning. It also needs to be diluted in filtered water as chemicals in tap water will affect it. Has little or no taste. If you can remember take it as your last drink again at night. I do 20 drops in each drink.
Thank you for this video. The gut is the second brain and best to feed the good bacteria and starve the bad bacteria with a healthy diet. Organic fruits and vegetables are key. ION gut support is critical for most because the soil microbes are deficient in most farming cultures. Probiotics are not good for the long term because they minimize the variety of good bacteria which is key to a healthy microbiome. I have heard mostly positive results with the correct small dose of MB. I am looking into it for my mother who is 83 and is showing more frequent episodes of forgetfulness and an inability to recall short-term conversations.
Thank you.
Love it🔥👏
Thank you for sharing thisinfo
My pleasure. Thank you for watching our video.
I am in the neighborhood so I will be scheduling an appointment!
Should do a video about Methylene Blue and Nitric Oxide.....
Lol proven benefits? From a big pharma seller?
Tell me you're joking
Prescription for MB??? Don’t need one … can purchase on Amazon!
All brands aren’t made the same though beware some are not going to be as clean
@@strawberryme08 One can figure that out .... killjoy
Sadly for me, Methylene Blue is an monoamine oxidase (MAO) inhibitor, and is contra-indicated for my carbamazepine/(Tegretol) use to prevent seizures. Many other meds have this same concern. Check them carefully.
Do you get this effect regardless of the dose? Would like to know if a microdose would be safe
I wish I could get one person, just one person, who could give me a way to work out the dose of methylene blue. No one seems to be able to give a precise dose.
ua-cam.com/video/o23duXLxON8/v-deo.html
Great information👍
This is good information for a 4-week study however I think we can all agree that 4 weeks study is not a long-term effect study
But 4 week in rat's life span is equivalent to much longer time in human life.
Your statement matters not and applies not to the reality at hand of the causation and effects of methylene blue and killing off beneficial bacteria or beneficial bacteria degradation in any part of the body such as the stomach small intestines colon large intestines etcetera... just like it doesn't matter when comparing two humans whether they will live to 100 years old or 50 years old if long-term they are taking a certain substance for a number of years you can see the causation regardless of how long the biological being will live
@@bedihabut then again. We aren’t mice
@@glory7086but those mice are us in another life time- as the universe always returns the favor/energy back to its sender/ creator- god spark, source, self, fractalized into experience in all dimensions and densities,mirroring love, from angles to minerals, plants and animals-- your mind body spirit - all is one and you are perceiving part of it.
to live - free as a bird
- when one chooses
to uncage ones inner innocence, - to live your life in lovelight , body makes changes, alchemy - to sustain life that chooses to sustain life.
. To evolve, is to live free on all levels of creation. - it’s your energy - experiencing itself - until reaching back to unity with All.
That is, was and will be.
4 weeks was sufficient for the cov id jabs
1 mg/kg humans is ~6-7 mg/kg rats, and ~12 mg/kg mice...and vice versa; good for extrapolating starting human doses based on studies in these 2 species.
Great video, helpful and respectful and funny at times
Glad you enjoyed it!
If all the studies examined are just 2 yr old then the logical mind would find that limiting. Maybe the learning mind is not hindered by the logical mind. I am just glad any studies are being done on M.B. since pharma can not profit from its sale. Glad you are reviewing M.B.
Are the studies not done with intravenous MB? In which case what will then concern us with orally taken MB??
I started off with 5mg. My urine was very blue. I stepped it down to about 3mg. Today is my third day. Hopefully it helps with ATP production and mitochondrial function.
Does it help with co infection in lyme and bebesia?
Gooosh, this is so hard to get in Euroope, and ordering from USA it costs like a leg.
Do y'all use pharma grade or usp 99.5% purity?
Maybe in the near future they can do studies on intra-nasal, transdermal, and intra-ocular admission of methylene blue. Could potentially bypass the gut altogether, maybe with different benefits? Quite interesting.
Interesting- I found this video because I googled MB because I saw it as an ingredient in eye drops and wanted to find out what it was.
Will make your eyes a bit sore but if you have eyelashes falling out it will help with that.
@@scottishpensioner2447 Yes! I saw that too, I came across some studies that said those eyedrops could be potentially harmful but I think it was due to the other ingredients in it… I am particularly interested in it for eyes because I have a genetic disorder of the retina, or the concentration of a lot of mitochondria/ATP is affected. But I don’t want to go putting stuff in my eyes and go blind all together! Lol would be hard to explain that to my ophthalmologist :-) there Hass to be a low-dose ratio with some other ingredients, maybe like vitamin C (which I have seen used in the eyes before)… Hopefully someone will see these comments and they will know some thing about that!
inject it obviously then
@@Keep_Focus_UK Well, I was thinking more like eyedrops, nasal spray and patches or lotions. I think it is being injected under certain circumstances. Especially for studies maybe, in animals.
I’m 56 years old and Carnivore since January. My gut biom is just fine with zero plants! Also I have been on methylene blue since November 22nd 2023 and I take it orally in drops. Started with 2% tincture and now a 1% tincture. I take it several times a day and have noticed nothing negative. I get blue pee and it goes from really dark blue to light blue and honestly find no problems with it. I used it at max amounts at first to see if there’s any negative side effects and if I could handle it. I handled it fine and I feel it’s damn safe. I do feel the energy uplift for sure.
How can you tell the microbiome is fine still? What tests were run?
@@kukensson I don’t need no stinking tests man!! LoL no really I know in two ways. # 1. Another person, male carnivore had a before and after done and it’s better as a carnivore. # 2. I can tell by there being no change in my action.
@@RA82828 angry? No way. Unhinged? Ummm, maybe? LoL
A video from a different source mentioned that using MB reduces the # of red blood cells circulating. Can some one explain the mechanism of interaction to cause this and should it be a concern?
Hello dane, I take 10 drops every day since 10 days now and my Tongue is not blue, everything is normal besides a tiny bit bluish urine color. So what is the deal that I do not get a blue tongue? Is it possible I have some enzyms that destroy Methylene Blue?
Would you have any information on how the MTHFR and COMT genetic mutations might affect dosing?
Yeah like hes gonna answer you?
@@johnwarner8569 doesn't hurt to ask.
just do some saunas if you're concerned (concomitantly with therapy) but "check with your doctor"
Sauna? Please delete your yt account.
Cut out fortified wheat, especially folic acid.
I've been taking it for 2 weeks.
I have noticed that my shoulder joint pain has diminished. I take five drops a day in the morning. I have read to start out with small doses and work out if necessary. The small doses seem to work best for me. I tried 20 drops but it made me feel fatigued.
I think im going to take a break
From in one day a week.
I'm also curious about its effects on parasites.
I heard from doc 10 days on 3 days off.
The fatigue happens to me as well. But personally I have found it to be from my liver and hydration... But I have hepc... So I chug a few glasses of water with mine and I found it does make ALL THE DIFF... Just thought to inform you because meth blue is a god send for me. I wish more ppl could find the benefits as I did. I have completely quit my Lexapro as well as the physical benefits that this has brought me. It's worth a try.
@@satanzmoma how much are you dosing now?
@@kmac6691 about 4 drops in am. And sometimes even 3 to 5 in the pm after dinner (depending on what all I am doing). Mine is "aqueous solution"..? 30ml of 1% ... so. Whatever my 5 drops equals. Not sure.. hope it helps..
What was the biggest benefits you experience frm taking MB ? @santanzmoma
What if you bypass your gut with a sublingual troche, is that possible, and would that make any difference?
One of the Russian doctor recommended to take MB with the very first signs of covid. I till today either the first signs of cold or flue and it does help in terms of symptoms and time. When I take it usually I am sick no more than 2,3 days without high fever. I also gorgle my throat with it when I have sore throat. I also add it to my moisturiser cream.
Can you speak to the safety of taking this long term for symptom management?
If you have covered this topic, can you point me jn the right direction?
And are there studies addressing long term use and safety?
I am taking it at a dose of 10mg once daily and it is the only medicine or supplement to positively impact my lyme and cfs symptoms and I dont want to stop taking it, but this worry is lingering in the back of my mind. Many thanks for any insights you may have.
How long after you started taking it did you begin to notice a difference? Also your 10mg is that taken straight or are you mixing it into something. I take 10mg but I put it in a smoothie which I divide over two days.
@@l.bevand3503 I take 10mg in the morning daily, in a multivitamin drink that has vitamin C (ascorbic acid), and I drink it before food. I felt a big improvement after about 1 month on the full dose, it took me a couple of weeks to work up to 10mg, so maybe 6 weeks all up. My symptoms are not fully gone, but they are much less and my energy is significantly better, I feel like I can function where I barely could before.
@@l.bevand3503 did u notice any benefits ? if no benefits why take it ? Just for placebo effect ?
Talking about dosage in mg, is it in pure MB powder form / in solution?
Any thoughts for adult male yrs chronic mj smoker, with daily stomach aches.. could this help?
Any kind of anti oxidant will benefit smokers. N.A.C has promising benefits for lung health as it helps produce glutathione in the body
I am so confused i am 50kg how much should i take in dropper for co infection
Help me out here bro.
I'm confused to why we measure MB in milligrams when liquid is measured in ml?
Some videos measure in it in drops but I've found drops are inconsistent in volume, it would be nice to measure in mL as it is the scale on the side of a measuring syringe👍
Great point! Would love more clarity on dosing indeed!
Exactly my thoughts 👍
So ml is just the volume of liquid. The mg represents the amount of whatever compound is suspended in the liquid.
Vials will be labeled like 5mg / ml, so you know that for every ml of liquid, 5mg of the compound is in it.
Some may be more or less concentrated.
Methylene Blue is a powder so, the bottle you buy determines concentration per drop. Get USP grade for purity and mix concentration peace of mind. Really though it's toxicity level is so high if your close I think its fine. I mean some of the doses recommended for clinical treatment is super high and that is intravenous.
@@jidun9478it’s not all bought in powder form it’s often in drops and some mb is cleaner than others
I thought Navy, particularly submarine personnel, have been taking this for a long time. Is this true? And if it is, why are there not more studies?
If that is true, then there most likely are studies, say old ones from the early days of underwater craft. Would make sense if MB helps increase the uptake of oxygen, then what a great group to use MB, when oxygen is questionable.
yes....goes way back! I'm sure it helps all those STDs the military gets when pulling to ports .... and you know why, the good studies are hidden on purpose.
I used mb to stain in microbiology but wasn't aware we could ingest
But you want the usp Phama grade the other one is not good for you!
Studies before 1930 were free from the bias and control of big pharma, just sayin. Newer is not always better. I appreciate your concise and informative videos on this topic.
even excess consumption of retinol vitamin A will shuffle your gut biom big way in not so wanted direction
imagine nr of all such effects we don't account before our meal and taking supplements
The Russia study mentioned suggests that it may increase H-pylori. Does anyone have any experience with using MB for Hpylori?
Decrease h
I've been taking 6-8mg MB daily for about three weeks now. Within the last week I've developed a rash that started on my legs and one arm. I thought it was mosquito bites at first. Now it's more spread onto my stomach, hips, shoulders area - where clothes slightly rub. Since I've not changed anything else, I'm wondering if MB is causing this? Is my body adjusting to it? Should I cut my dosage? Stop completely? I did mix some MB with lotion to apply topically but only on my legs so the widespread rash is puzzling. Not really itchy, just splotchy ugly tiny red bumps. I'm really hoping I don't need to stop taking but am not sure where to go from here. I can't consult a doctor because they will be clueless about MB and just prescribe an antihistamine or something. I do use RL/NIR therapy also for the added benefits. Any input would be appreciated! Thanks.
Holy hell,the preamble
Dude just fast-forward ... is much easier to do that than to take time out and complain in the comment section😂
thanks! Can you perhaps explain why after taking MB I get swollen gums? I started taking Vit C but not sure how much per 1 mg of MB.
It is likely bringing more oxygen to your gums which could increase inflammation, or it could be causing an anti microbial effect by fighting bacteria on the gums, increasing inflammation…
I would take capsule form. I found it on Amazon
Any difference between this and any on amazon...?
Just make sure it’s pharma grade. I searched methylene blue supplement capsule form on Amazon and got a good result. $30 to revitalize my health, wow what a deal
Can you take M blue sublangua?
Is that 15mg/kg of the pure crystals? or 15mg/kg of the 1/100 solution?
4 weeks of mouse life correlates to how many weeks of human life?
I am a firm believer in MB is really helpful with energy production. Even though you can use up to 40 drops a day I wouldn’t recommend that. Start slow to keep the herxheimer reaction at a minimal. I use Earth Harmony USP grade from Amazon 4-5 drops daily. One drop is approx.0.5mg-bottle states 20 drops=10mg. If this is something you’re body needs, it could change your life.
Has anyone read about the study saying that MB is a carcinogen? Can we get a breakdown of that study because this video was so helpful.❤
An antioxidant carcinogen... seems off
Extremely high doses
I thought it's was quite the opposite? What study did you see?
What about mb effects on eNOS? NO is crucial for healthy blood vessel dilation and function but I hear MB blocks that. Can you comment on that concern?
then throw in some saunas, red light therapy, etc to bring back the NO.
Nitric oxide is bad, pharmaceutical companies are the ones who pushed it as a good thing.
What is eNOS?
I think you also have to take me into account what form the methane blue is in. Oxidized or reduced. it is quite possible if you oxidize it with ascorbic acid and take it in the reduced form (leuko: white in color) on an empty stomach it would not enter the intestine.
Would like to see a study on this
I take 8 mg each am as one of the MANY things that I do for Alzheimer’s prevention.
Were these dosages such as 15 mg per kilogram adjusted for a equivalent human dose?
At 8:00, he said to use 0.5-4 mg. per kg.
MB has done zero for my tinnitus , which unfortunately has become debilitating in the last 5+ years … but hopefully Blue can help stave off the earlier cognitive decline that’s been associated with having severe tinnitus.
Talk to your doctor about supplementing with omega 3 oils and B vitamins
yes ive had no change in my tinnitus after good dose once a day feel better energy tho and have used for injuries re bac inf in my pets and works well topically also i have a very clear mind
@@MDcustomRx thanks but I’ve tried everything there is to try. I’m a good $150-200K into every form of therapy there is with no results. Just trying to hold out now until an objective treatment for tinnitus is available. There’s high hopes for Dr. Susan Shores device out of Michigan University. Thanks again
Got rid of tinnitus taking liquid chlorophyll as per the bottle instructions.
You need to make sure you're getting all your vitamins, and minerals and all your proper macronutrients as well. I'd look into high dose thiamine therapy - EONutrition is a great channel on UA-cam with lots of fire 🔥 info! Also, research Traditional Chinese Medicine - I think tinnitus is considered external wind, so you would look for herbs to treat that. Hope this helps!
That s great news 👍🏻 i started to take methylene blue a month ago and i was trying to find an answer to this question. Prof Lima suggest taking MB but didnt give an obvious answer about the gut flora. At some point he kind of implied that it may do some harm in some context. Anyway thank you for providing this info. On another note, im taking 0.5 mg/ kg but didnt feel anything yet in terms of mental functions. Kind of disappointed. How long would it take to see some benefits?
I take 1 1/2mg and it's amazing
@@michelemcneill3652 what benefits you got ?
so you take 1 and 1/2 mg per kg of body weight daily? So do you take at least 150 drops of MB per day? assuming for a 70 kg person@@michelemcneill3652
You can increase it to 4 mg./ kg.
but how do you manage to drink it? ıt is a lot ! 4 mg / kg makes 640 drops of 1% solution which makes roughly 2 table spoons. Do you divide the dose throughout the day? @@johnkrieger185
MB changed my life primarily in its MAO inhibitor action. I got my brain back! 10 mg total dose per day taken as 10-20 drops 💧 at .5mg/ drop. When I got CoVid I noticed that my urine was no longer blue so I doubled the dose and still only slight blue tinge.
Did MB help with your covid?
Did MB help with your covid?
MB helps with covid
Dane can speak very fast, at the last few seconds he rattles off that a common dose is 0.5mg's per kg's. I'm at 104kg, so a good safe does is 52mg's of MB. I mix the powder version to get 1% solution which loosely translates to taking 1mL or 60mg's per day.
I've been doing it since 4/23 ever weekday. I also combine it with Redlight Therapy.
I've got a spinal cord injury that leaves me in chronic neuropathic pain 24/7 which means I'm chronically fatigued.
MB has been a great help in giving me just a bit more focus. I think it would work even better for me if I was not on neuropathic pain medications that have a huge brain fog side effect. It just gets me back to almost normal.
If ingested orally,(Which I presume most people are) does it stain your teeth?
I really want to try MB, but do you really need to get a GPD6 deficiency test beforehand? My doctor just won't give me that test unless I have anemia. I did get a CBC test and everything looks great.
Yes, the GPD6 test is important, best practice would be to screen for that deficiency prior to use. Maybe you can reach out to other providers willing to test you, or pay out of pocket for the test. Thank you for watching!
@@Dr.DaneNewvilleRPh
Do you know if the 23andme genetic test covers this gene?
I like bph labs MB liquid drops
If using it 10 days on and 3 days off, is it possible to take any medication usually forbidden whit it like for example trazodone sleep pill in the 3 days off ? I am wondering how long does it take for the methylene blue to be eliminated from the system
I take it with trazadone just fine avoid antidepressants
MB leaves in 6hrs.
You have to fast for maximum health especially if you have a cancer as the cells need to repair and it's the only way they can, Mighty difficult though, personally I have resorted to hypnosis for water fasting.
I'm wondering if you could provide feedback on this dosage: 1% aqueous solution: .5 ml ( half the eye dropper) into 700 ml of water. Standard water bottle. is this too much? I just started this today. once per day. I can't determine either by the formula of .5 - 5 mg per kg body weight. I'm 80 kg.
I hope this helps, a 1% solution is 10mg of active ingredient per 1ml, so 0.5ml is 5mg of active ingredient. So from what you are describing you have 5mg of methylene blue per 700ml of water. Hope that was helpful. Thanks for watching!
Can you equate dosing in drops?
I take 3 drops 3 times a day
No because different bottles/brands contain different amounts per drop so it depends
read Mark Sloan's book on MB on amazon
Capsule form is better because it’s easier to dose. I found it on Amazon
I've heard, here on YT, a mention of "less is more", cuz I dunno what you 0.5 means related to the small dropper i use?
check the bottle. It should give in mg per drop or for 10 drops
@@davelawson2564 Holy Cow, right you are! It says 3-10 drops in water 4X daily. So while less being more, more often gives a nice slow build, or what's the deal with that?
Yes less is more like homepathic medicine is.
@@wasabiginger6993 Weal phew, cuz i don't got much left & it'll be a while before i can get more & strrrreeetttch it
At about 80 kg, just .5 ml/kg would be 40 drops per day. I take 20/20. I'm not diagnosed with anything but a friend noticed a tremble in my left hand. I also found it difficult to edit pictures on my phone using my thumb. That was the true test that something was wrong. Maybe early signs of Parkinson? I'm doing 20/20 drops and noticed I can now edit photos without any trouble after about a month, but I still have slight movement.
Ok where to get this stuff??
endalldisease.com
Would love to get in capsule form!
We compound MB in capsules. Thank you for watching our video.
I found some on Amazon
This would seem to indicate that overweight or obese individuals are in a squeeze, since their microbiome will have approximately the same sensitivity to disbiosis as someone of normal weight, but they would require a larger dose of MB to get similar distribution to all their mitochondria, including in the brain. Does this make sense to you?
No. My experience is that no matter the dose, it gets everywhere.
A holistic practitioner tested MB on me on how much to take. Supposed to take 3 drops of 0.5 MB in 16 oz water, sip throughout the day, ONCE A WEEK. It might be worth testing how much you need. You'd need a practitioner or chiropractic who does muscle testing.
does that translate to 1.5 mg per week? thanks. I ask because I take MB capsulated and have found 1 mg doses to work well for me.
Yes
Everywhere I see the dosage in mg which is a dry measurements. I use liquid 1% so I'm curious what the ml dosage would be p/kg?
find out the amount in mg in liquid.
mg to ml is .000 (three space) which doesn't make sense for dosing hence the reason I asked the question.
My brand is 1 mg per drop .
what brand is that please?@@leighnapier4505
@@leighnapier4505 Hi, what brand do you use? Thanks
Can we order this from you? Thx
@sunnyla2835 I know the pharmacy has an OTC Methylene Blue. Or your doctor can send over a prescription.
www.endalldisease.com. I would NOT use amazon or an MD Rx.....you want toxin free
@@DanielZatarskiin the USA it’s otc? Not sure about that 😅
Troscriptions I find to be the best source
That is a huge dose, 15 mg/kg to 50/kg. 0.5-4mg/kg is what I follow.
I reg take about 4 drops 2 times a day... 1 % solution... I have no idea how to figure that amount.
@@satanzmoma
What does it do for you?
@@mballer Well I was on Lexapro for depression but stopped when I started meth blue. As long as I take it daily I don't feel as sad for sure. But I also use it because I work out regularly. It helps a whole lot with muscle fatigue for sure. Just make sure you drink water with it. Sometimes I'll wait till midnight to work out and take my blue an still work out for hours before feeling tired. I also noticed the muscle sorness never lasts. Normally I wake up sore from the days before but since using it I only feel a slight sorness in my core area but I do work the fk outta that area anymore so might be why. Iv not felt the need for depression meds and to work outis all the reason i need. Plus it helps with my adhd alot.. but take the few days off every couple weeks like they suggest because if not it will loose potency... good luck. I'd rather buy weird legal blue bs than pharmaceuticals.. wouldn't you?? BEWARE YOU PEE SMURF BLOOD. WEIRD BUT just a side effect.
Can you give a daily dosage idea for a 70kg adult male. i have trouble as others have in the comment section. ie one person thinks its 100 to 800 drops a day. A data sheet with dosage V weight would be so beneficial. Just an idea.
A conservative dose for a 70 kg adult would be 35 mg/day. Given that it has a half life of about 5 hours, you may consider splitting the dose up to 18 mg every 12 hrs. Or just take it in the morning if it gives you too much energy at night. You will just need to see how many mg per drop you have on your solution
8:40. 0.5 x 70 = 35 mg. 4 x 70 = 280 mg.
I started with one drop each day. I found that 3 drops 3 times a day was perfect for me.
Where is everyone getting MB? I'm in Canada if that makes a difference.
@@leemellor3972 I order mine off Ebay.. I get BPH brand which is pharmaceutical grade and was recommended by a clinic on UA-cam.
A milligram equals drops?
How can we get mb suppositories?
Just make your own.
We can compound them when a valid prescription order
I don't know the molecular size of methylene blue. But if it could be made into a liposome, then the entire gut microbiome issue would be entirely avoided.
So if I’m 68 kilograms how much should I take in milliliters ?
Good question, Dane gives you the dose at the very end, but he speaks soooo fast it is easy to miss: "0.5mg's per kilogram" or in your case 34mg's. With 1% grade @ 0.5mg's per drop that is 68 drops. I mix my own 1% solution and take it by the dropper full since I'm 104 kg. Droppers when full generally hold 66 to 70 mg's of solution which is also 1mL.
It all can get a bit confusing I know.
CN it be taken with LDN
Yes
I am not good at math so can't translate that into pounds. Aren't there American dosage amounts available?
Can't find it in France.
You find it on etsy
15 mg - 50 per kilogram a day😳
for a 150 pound person that would be 1,125mg & 3,750mg a day, Who the fuck would take that much unless they’re getting a cancer procedure in a hospital intravenously? That’s a very extreme test so you can get ridiculous results. Most people that we work with are taking anywhere from 2 mg a day up to 40 mg a day and there’s very few taking 40 mg a day because most don’t have serious health issues they’re working through other than a little depression or just wanting their brain to be on point.
here’s the problem with studies…
1. We have to extrapolate from a mouse study.
2. This is not even close to what a real world comparative seeking study would look to achieve.
Personally, I would do a one to two Month study where the mice were given .25mg per day. then they would actually see results comparative to what most people are probably taking daily or consistently. However I will say that through the fact the 15 mg dosage didn’t have a negative leaning affect, that does bode well for the fact that methylene blue is extraordinarily well tolerated, especially through the pathway of digestion and hydrochloric acid.
Hi, what MB do you use? Thanks
@iamjacksundyingaddiction6595 not sure the relevance of how much I take but I take anywhere from 5 mg up to 50 mg depending on if I choose to take any on a certain day. I have zero problems anywhere in my body or mind so I do not need methylene blue. I use it as a nootropic, and we create MB products in our lab. Therefore I work with many people that have brain, fog, depression, and neurodegenerative disorders.
My only use is as a simple, nootropic, and when I have been overworked for many days with very little sleep. It is an amazing remedy for keeping the brain laser sharp even on less than three hours of sleep a night over repeated nights.
@@AZMYTHKAMINSKI what is your brand also can you send link? Thank
@@AZMYTHKAMINSKI While it may be of help to you, it appears that you may need to slow down a bit. You didn't read or answer the actual question. That happens when you are too worn out or stressed.
@@miakialchemy what question if not the question that this doctor already answered, which was explaining that there was no disturbance that they could actually tell specifically from using a massive amount of methylene blue to disrupt the also good bacteria in the Microbiome. What do you want to know?
Can you please talk at some point if methylane blue is beneficial for cancer?
We will cover this topic in a future video. Thank you for watching. ❤️
Yes it is. Look up Dr Berg and Methylane Blue. He has 2 videos on it.
The body is capable of causing apoptosis to mutated cells (cancer). Fasting, broccoli sprouts for the high content of Sulfer, medicinal mushrooms that help improve the communication between cells. When your body can identify the cancer cell it is equipped to destroy it through apoptosis. The problem is that the inflammatory seed oils, most prominent in our modern packaged food diets will disguise the cancer cells, blocking communication to other cells.
Min 13 he mentioned something
The expansion of oxygen throughout the cells in the body due to methylene blue, which is about a 36% uptake, mean that it’s automatically good against cancer. Any increase in oxygen will help to slaughter the cancer cells.
@decillion-
2 days ago
@MDcustomRx so, based on these studies, if a man weighs 100kg what is the sweet spot of how many mg of 1% Methylene blue liquid he should take to gain cognitive function without messing up the microbiome? You mention 0.5mg to 4mg per kg bodyweight per day: how many drops from a pipette would that typically be? If one drop is, say 0.5mg, are you saying he should take between 100 drops and 800 drops per day?
Figures he won't answer you...
If you're going to be your own doctor and take MB, you've got to be able to think and understand your own body. I took one drop/day for a week. Then upped it to 2 drops. Then I had the herx, adjusted accordingly and keep moving forward.
It'd be incredible foolish to jump in and start taking "the recommended dose" which is really an upper limit baseline of what's safe. Take your power back over your health and use some.common sense ffs!
There is an (unpublished) suggestion from Dr Sabine Hazan MD that MB reduces bifidobacterium. If that was true, it would be significant. As I say, as yet unpublished……
I'm not a mouse
.05 max dose and take every other day. if your focused on a healthy microbiome in your diet your stomach will be fine. those with unhealthy flora are doomed already. fix it