Bilirubin Metabolism & Jaundice - Gastrointestinal (GI) Physiology & Pathology- Physiology Series

Поділитися
Вставка
  • Опубліковано 8 лют 2025
  • Biliverdin, Bilirubin, Bilinogen Metabolism & Jaundice (Hemolytic jaundice, Hepatocellular jaundice, Obstructive “cholestatic” jaundice…Prehepatic, hepatic, posthepatic jaundice | GI Physiology
    🤰 ObGyn Highyields Course: www.medicosisp...
    🚨 Emergency Medicine HighYields Course: www.medicosisp...
    😷 Surgery HighYields Course: www.medicosisp...
    💊🦠 Antibiotics Course: www.medicosisp...
    💊 📛 Toxicology Course: www.medicosisp...
    💦 🐳 Kidney Physiology Course: www.medicosisp...
    📝 Download my handwritten notes: www.medicosisperfectionalis.com/
    - PREMIUM COURSES not available on UA-cam:-
    💊🦠 Antibiotics Course: www.medicosisp...
    💦 🐳 Kidney Physiology Course: www.medicosisp...
    ❤️ Cardiac Pharmacology Course: www.medicosisp...
    🧪Acid-Base Course: www.medicosisp...
    🧠 Autonomic Pharmacology Course: www.medicosisperfectionalis.com/
    🧪 Electrolytes Course: www.medicosisp...
    🍱 Endocrine Pharmacology Course: www.medicosisp...
    🧠 CNS Pharmacology Course: www.medicosisp...
    💊 General Pharmacology (Pharmacokinetics and Pharmacodynamics): www.medicosisp...
    ⁉️ Questions and Answers: www.medicosisp...
    📝 Notes: www.medicosisp...
    🗳 Complete the Survey: airtable.com/s...
    📊 My favorite Productivity App (Airtable): airtable.com/i...
    🎁Free Stuff: www.medicosisp...
    💊 Pharmacology Lectures: www.medicosisp...
    😍🖼Animated Mnemonics (Picmonic): www.picmonic.c...
    UA-cam PLAYLISTS:
    ► 🧠 Physiology Playlist: • Physiology Introductio...
    🧫 🦠 Microbiology and Infectious Diseases Playlist: ua-cam.com/users/pl...
    ► 🩸 hematology videos: • Hematology/ Oncology
    ► 💪 Rheumatology: • Rheumatology
    ► ❤️ Cardiac Pharmacology: www.youtube.co...
    ► Biochemistry 🧪 : • Biochemistry - MCAT, ...
    ► 🙌 Support me on cash app: cash.app/$medi...
    ► Support me on Stripe: donate.stripe....
    ► 😍 Support me on Patreon: / medicosis
    ► Support me on Venmo: Venmo: venmo.com/medi...
    ► 🥰 Support me on PayPal: www.paypal.me/...
    ► ☕️ Buy me a Coffee: www.buymeacoff...
    ► 😚 Join my Channel on UA-cam: / @medicosisperfectionalis
    ► 👨‍🏫 All of my premium courses are ON SALE: www.medicosisp...
    📚 Recommended Books: www.amazon.com...
    ► ❓If you have any questions, please email me at: medicosisperfectionalis@gmail.com
    🗳 Complete the Survey: airtable.com/s...
    🎁 Small gift: here are 2 FREE audiobooks from Audible amzn.to/2FQurW0
    📖 Try Amazon Kindle unlimited for FREE, they have some good medical books that you can read for FREE. amzn.to/2UceoG2
    --If you have joined my channel on youtube (the join button that's next to the subscribe button), then go to the "community tab" and you will find some member-only posts.
    ►Website: www.medicosisperfectionalis.com
    ►Patreon: / medicosis
    ►UA-cam: / medicosisperfectionalis or:
    ► Like my page on Facebook / medicosis
    ►Follow us on Instagram here: / medicosisperfectionalis
    ►PayPal: www.paypal.me/...
    ►Venmo: @medicosis
    ►Facebook: / medicosis
    ►Twitter: / medicosis
    ►SoundCloud: / medicosis
    ►TikTok: www.tiktok.com/@medicosisp/
    ►LinkedIn: linkedin.com/in/medicosis-perfectionalis-873886197
    ►Snapchat: / medicosis
    ►Pinterest: / medicosisperfectionalis
    ►Rumble: rumble.com/use...
    ► Tumblr: / medicosis
    Thank you so much for supporting my channel! Love ❤️& Happy studying!!
    😍🖼Animated Mnemonics (Picmonic): www.picmonic.c...
    📱Save on your mobile phone bill: fbuy.me/q6bMj
    📊 My favorite Productivity App: airtable.com/i...
    🙋‍♀️ Qbank (TrueLearn): truelearn.refe...
    🙌 Support the channel: donate.stripe....

КОМЕНТАРІ • 170

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Рік тому +6

    😷 Surgery HighYields Course: www.medicosisperfectionalis.com/

    • @dr.fernazmbbsmd44
      @dr.fernazmbbsmd44 Рік тому +1

      Cannot upgrade to to tier 3 showing error 404

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Рік тому +1

      @@dr.fernazmbbsmd44 Dear Doctor! First, thank you for subscribing to tier 2…Your support means the world to me! Second, try doing so on your desktop computer (you can also try a different web browser). Here’s my email if you need anything: medicosisperfectionalis@gmail.com
      I can’t wait to hear your opinion on my 300+ Premium Videos!
      I am really grateful to you!

  • @aasemahsan
    @aasemahsan Рік тому +40

    13:52 Jaundice
    18:47 Pre-Hepatic & Post-Hepatic Jaundice comparison
    21:44 Comparison among Pre-hepatic, Hepatocellular & Post-hepatic jaundice
    23:41 Congenital Pathologies

  • @jasminels
    @jasminels 3 місяці тому +14

    *literally me every time i watch a medicosis video:* "this is my new favorite video"

  • @kitsunefire92
    @kitsunefire92 11 місяців тому +40

    Not sure if your intended audience includes Medical Lab Tech students but I appreciate these videos none the less.

    • @MirandaLovesPathology
      @MirandaLovesPathology 5 місяців тому +2

      Lab tech here!!! I binge watched so many Medicosis videos during school…I still do sometimes for a refresher ❤️🫡

    • @kitsunefire92
      @kitsunefire92 5 місяців тому +1

      @@MirandaLovesPathology they're so good! and they help me so much!

    • @TheLabHouse-t7h
      @TheLabHouse-t7h 5 місяців тому

      Hi , I'm a lab technologist and working on my channel to help others out, do visit my lab house if you want! 😃⭐

  • @nooralhoda8529
    @nooralhoda8529 Рік тому +28

    It's been a week since I've searched for your jaundice video 😅, I'm happy that you've posted it today 😍

  • @messilionel12345
    @messilionel12345 10 місяців тому +14

    My favourite physiology channel: Medicosis perfectionalis

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  10 місяців тому +3

      Thank you so much, Anthony!

    • @Dr_strange_2652
      @Dr_strange_2652 5 місяців тому

      My best online teacher
      I am lucky enough to get ur classes in online....❤❤❤❤❤❤❤​@@MedicosisPerfectionalis

  • @samaafaiz6523
    @samaafaiz6523 Рік тому +9

    How talent you are at interpretation staffs in scientific way.

  • @waelfadlallah8939
    @waelfadlallah8939 Рік тому +23

    If the stool is not brown we need to talk, if it floats we need an appointment and if it's pencil-shaped we need surgery!😅
    Great explanation encompassing all bilirubin related pathologies 👍

  • @imeann...
    @imeann... Рік тому +3

    I cannot express how much this helped me. Really really grateful

  • @raphaellaballa6884
    @raphaellaballa6884 Рік тому +7

    Honestly you are a rare gem ❤

  • @thehigherevolutionary
    @thehigherevolutionary Рік тому +4

    Thanks!

  • @kdhani9196
    @kdhani9196 Рік тому +3

    So far the fav channel ❤

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Рік тому

      Thank you so much! I appreciate you!
      Can you please help me by sharing my videos with others?

  • @shafiqkassim_
    @shafiqkassim_ Рік тому +4

    never imagined myself laughing and learning medicine. BIG UP MEDICOSIS

  • @احمدصادق-ك8غ
    @احمدصادق-ك8غ Рік тому +5

    Thank you so much medicosis, follow your videos from egypt

  • @alanwaterman1328
    @alanwaterman1328 Рік тому +3

    Yes it all makes perfect sense with your words of wisdom.

  • @pashenw5519
    @pashenw5519 Рік тому +4

    congratulation for 1 million 😁

  • @sanahameed4205
    @sanahameed4205 8 місяців тому

    U r my real life hero....thank you for existing ❤

  • @0xApollo
    @0xApollo 4 місяці тому +2

    You make me call pathology a babyyy
    Thanks so much 🙏🏻 💓

  • @nehakurmi538
    @nehakurmi538 Рік тому +4

    Great explanation

  • @mahimapearlin7432
    @mahimapearlin7432 Рік тому +1

    Talented sir❤❤❤❤❤

  • @Dr_strange_2652
    @Dr_strange_2652 5 місяців тому

    Hey medicosis
    Please make a live session with us
    As we can see you directly.. don't know why i feel great connection with u medicosis. I never have so passionate and caring teacher like u ever in my life😢😢. I don't know if i get the opportunity to meet u or not! But its my belief that i will get the opportunity to meet u somewhere inshaAllah..
    please sir if possible please have a visit to Bangladesh.....
    Take care and keep sharing your wisdom Sir

  • @ubaidullah1611
    @ubaidullah1611 7 місяців тому +2

    Awesome lecture

  • @lanaalfares8350
    @lanaalfares8350 6 місяців тому +1

    Thank you so much
    I appreciate your effort to make this masterpiece (mastervedio)
    جزاك الله خيرا

  • @madihatahreen4851
    @madihatahreen4851 2 місяці тому

    This is such a great video man!! Thankyousomuchhhhhhh❤

  • @Dr_strange_2652
    @Dr_strange_2652 10 місяців тому +1

    Another boss level explanation ❤❤
    Greetings from Bangladesh

  • @gironkid8303
    @gironkid8303 Рік тому +2

    ❤❤❤❤❤❤ saving my grade ❤❤❤❤❤❤

  • @thebeardednurse187
    @thebeardednurse187 13 годин тому

    Great video. Keep em coming.

  • @tinghuanhsu3469
    @tinghuanhsu3469 Рік тому +3

    it's awesome !thank you

  • @Wandererp_19
    @Wandererp_19 2 місяці тому

    Bestest video❤️
    Thanks🙏

  • @saumyalandge7349
    @saumyalandge7349 Рік тому +2

    Thank you so much

  • @rispaadoma5734
    @rispaadoma5734 6 місяців тому +1

    Love this ❤

  • @smitakumari4446
    @smitakumari4446 Місяць тому

    It's very helpful thanku for explain this

  • @Mahmoud-Alzaher
    @Mahmoud-Alzaher Місяць тому +1

    Thankful 🥰

  • @shams-100p
    @shams-100p Рік тому +4

    Brilliant 🤩

  • @tiss
    @tiss 8 місяців тому +1

    Very informative video... Thank you

  • @alexsheremett3097
    @alexsheremett3097 4 місяці тому

    Fantastic thank you!

  • @yomnahabashy3254
    @yomnahabashy3254 Рік тому +2

    ‏‪ ‏‪10:39‬‏
    Famous Egyptian professor.. Dr Nagi ❤❤❤

    • @Salma20053
      @Salma20053 2 місяці тому

      هو مصري كمان😂

  • @lolo-dv4yi
    @lolo-dv4yi 11 місяців тому

    19:10
    How obstructive jaundice can be intrahepatic? doesn't it confuse with hepatocellular jaundice??
    Thanks for this greatness really❤️❤️👏

  • @jacenite8517
    @jacenite8517 Рік тому +1

    Sir please I’ll like you to go a bit deep into creatinine, lft and rft with practical applications so I can prepare before exams

  • @asifshahriar9685
    @asifshahriar9685 2 місяці тому

    Thank you❤

  • @mitanshusharma5944
    @mitanshusharma5944 Рік тому +2

    Itss Just Awsumm. Toooo Goood.

  • @naaengmann2117
    @naaengmann2117 7 місяців тому +1

    really helpful!

  • @moinn230
    @moinn230 Рік тому +1

    Please make video about hepatitis ❤

  • @anastasia1431
    @anastasia1431 Рік тому +2

    I literally manifested this video 😂 God bless you

  • @ABC-fv7ow
    @ABC-fv7ow Рік тому +2

    Superb🎉

  • @randomthingstovlog
    @randomthingstovlog Рік тому +3

    please don't skip ads..

  • @qamar997
    @qamar997 Рік тому +3

    awesoom❤🎉

  • @MichelleDespres
    @MichelleDespres 8 місяців тому +1

    Wondering if you could discuss this process with no gall bladder and also extremely low iron... I'm having infusions.

  • @-Emune
    @-Emune 6 місяців тому +1

    Not joking i opened the PDF given to us by the professeor and it is legit this video in slides 🤣🤣

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 місяців тому +2

      Wow! I appreciate you so much!
      Side note: Your wonderful professor never asked for permission or even said thanks!

  • @tmsff9893
    @tmsff9893 Рік тому +1

    1- the urobilin and Urochrom are the same?
    2-In hepatic and post hepatic what does make the urine dark if there is no urobilinogen?

  • @gironkid8303
    @gironkid8303 Рік тому +3

    I LOVE YOU MEDICOSIS

  • @Dr_joona
    @Dr_joona Рік тому

    Thankyouu so much👍👍👍👍👍👍

  • @shashishekhar----
    @shashishekhar---- Рік тому +1

    Good video

  • @SomaDler-cy4we
    @SomaDler-cy4we Рік тому

    Thank you.

  • @mohsenahmed1270
    @mohsenahmed1270 Рік тому

    Amazing 🤩

  • @ivymatimati
    @ivymatimati Рік тому +1

    Weldone this is short ñ simple

  • @aureliavruzhaj3191
    @aureliavruzhaj3191 7 місяців тому

    beautiful

  • @grahamsmith5768
    @grahamsmith5768 6 місяців тому

    I had jaundice, and it was a wake up call to look after my liver.

  • @shinn-tyanwu4155
    @shinn-tyanwu4155 8 місяців тому +1

    Great 😊

  • @okk2101
    @okk2101 Рік тому +1

    Great!

  • @moinn230
    @moinn230 Рік тому

    Thx bro❤

  • @shahadaljouf8638
    @shahadaljouf8638 11 місяців тому

    My question is the bilirubin greenish color cuz our doctor said it’s colorless but once it differentiates in the intestine it gets the color and in urine it will be colorless

  • @lolo-dv4yi
    @lolo-dv4yi 11 місяців тому

    How is stercobilin produced in hemolytic jaundice? It is preheat defect so, it can't reach intestine so, urobilinogen isn't produced and it is produced from oxidation of urobilinogen??
    I wish I didn't misunderstand😢😢.

  • @kjasalewjathan
    @kjasalewjathan Рік тому +1

    Is jaundice the same as scleral icterus

  • @LeahRebecca
    @LeahRebecca Рік тому +1

    ty

  • @idea4022
    @idea4022 Рік тому

    10:41 Prof naji ❤

  • @meloukabelalia
    @meloukabelalia 9 місяців тому

    thank you but how conjugated bilirubin will increase in the blood in hepatocellular when the liver can not conjugate bilirubin !

  • @ibrahimgalal9136
    @ibrahimgalal9136 7 місяців тому

    10:40
    د/ ناجي اسكندر

  • @jaguararts2296
    @jaguararts2296 3 місяці тому

    Sir! Please add chapters in this video. So we can easily seek

  • @jacenite8517
    @jacenite8517 Рік тому

    25:16 Sir please I’ll like you to go a bit deep into creatinine, lft and rft with practical applications so I can prepare before exams

  • @medmindmap4931
    @medmindmap4931 3 місяці тому

    why does conjugated bilirubin rise in rotor's syndrome since it is a defect in OATP that take unconjugated bilirubin into the hepatocyte?

  • @kira01982
    @kira01982 Рік тому +1

    Guys, I have a question ❓
    I have jaundice from time to time with lower dried lips and feel sleepy most of the times.
    I did CBC test and all was normal except my bilirubin was way higher than peak ,the liver enzymes were OK as well
    POINT : I FAST ALL DAY ONLY TO EAT AT DINNER , is this common or related to liver damage?

    • @AAtkinson
      @AAtkinson Рік тому +1

      Sounds like Gilbert’s Syndrome. It’s a common genetic condition which leads to elevated bilirubin due to an enzyme deficiency of UTG1A1. Affects about 10% of Caucasians. When the body is under stress the liver produces less of this enzyme. Lack of sleep, excess exercise, dehydration, emotional stress. Fasting is a type of stress. I bet if you stopped fasting and drank more water the jaundice and bilirubin would normalize, or the bilirubin would be only slightly elevated.

    • @shubhamparande6002
      @shubhamparande6002 Рік тому

      Hey even I am dealing with same. My cbc test all was normal but sgpt was 125 . Can anyone help me out pls

    • @Z.almagdi
      @Z.almagdi 2 місяці тому

      It sounds like Gilbert’s syndrome, a genetic hereditary disorder where slightly higher than normal levels of bilirubin build up in the blood, causing jaundice., everything in CBC will be normal and okay except for bilirubin obviously. No treatment is needed but several factors, including FASTING for long periods of time like this , illness, and dehydration etc , may trigger symptoms! So don’t worry but be carful

  • @reh303
    @reh303 Рік тому

    As someone with autoimmune hemolytic anemia, this was very informative. Thank you.

  • @drdurdana3668
    @drdurdana3668 Рік тому +1

    Why stools are dark in hemolytic anemia plz clear it reason behind it??

    • @kzthluv5598
      @kzthluv5598 Рік тому +1

      Because of increase in the total amount of urobilinogen

  • @fatimamaryam3168
    @fatimamaryam3168 6 місяців тому

    Hi
    I have a question, if due to obstruction bacterias are not able to form urobilinogen and stools are pale then how the urine colour is dark, as urobilinogen has to be converted to urobilin and excrete in urine?

  • @ThinleyMbbs
    @ThinleyMbbs 9 місяців тому

    Sir doesn’t Alp increase in hepatocellular jaundice??

  • @Ahdbfbfbeh
    @Ahdbfbfbeh Рік тому

    How many liters of bile do we make per day or expect to drain into a tube?

  • @hamzaalghurbani
    @hamzaalghurbani 5 місяців тому

    I love that famous Egyptian prof 😂🤍🤍
    Two hearts one for him and the other ... 😂

  • @ValentinaKajcinovska
    @ValentinaKajcinovska 6 місяців тому

    Should urine always be yellow, mine is non colour at times. I call yellow bilirubin..

  • @عمادزيتاوي-و1ف
    @عمادزيتاوي-و1ف Рік тому +1

    Big like 🌹

  • @yanbingzhu2550
    @yanbingzhu2550 4 місяці тому

    Hi Medicosis, if the patient have hemolytic disease of RBC, doesn't their hemoglobin ends up in the urine and cause hematuria? Therefore, the urine will be red, full of hemoglobin? Why did you say the urine will be normal color?Thank you, medicosis.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 місяці тому

      There are 2 different types of hemolytic anemia (intravascular and extravascular). I was referring to extravascular hemolysis. You referred to intravascular hemolysis.
      Moreover, the video is concerned with the effect of bilirubin and its metabolites on the color of the urine, and not the effects of other factors.

    • @yanbingzhu2550
      @yanbingzhu2550 4 місяці тому

      @@MedicosisPerfectionalis I see. Acute hemolytic transfusion reaction must belong to the intravascular hemolytic anemia. RBC got killed and bursted by IgM antibodies in the blood vessel. The spleen macrophages probably did not eat those RBCs. Is Rh incompatible hemolytic disease of new born intravascular or extravascular? Do you have a video talking about the differences between intravascular and extravascular hemolytic anemia? Thank you so much.

  • @hello-un8gh
    @hello-un8gh Рік тому

    In hemolytic jaundace shouldn't be the urobilinogen in the urine increased? Both CB and urobilinogen in the urine give coca cola like appearance?

  • @mariama.sgodhelpme2264
    @mariama.sgodhelpme2264 11 місяців тому

    The Egyptian professor is he Dr Nagy Iskandar ? 😅 I think i heard him saying the same way from many years

  • @ivymatimati
    @ivymatimati Рік тому +2

    ❤❤❤

  • @mahmoudhassan6934
    @mahmoudhassan6934 11 місяців тому

    You are slightly affected by dr Nagi
    1973
    Chole conjugate
    Ca contrac
    And many things
    Watching you after him
    Best wishes from Egypt

    • @mahmoudhassan6934
      @mahmoudhassan6934 11 місяців тому

      I comment before this
      11.6
      Feeling proud 😊
      Their is Egyptian teaches medicine concepts very well with brilliant accent even for American students.

    • @abdelrahmantarek7713
      @abdelrahmantarek7713 9 місяців тому

      هو مصري

    • @abdelrahmantarek7713
      @abdelrahmantarek7713 9 місяців тому

      شوف اكتر فيديو مشاهدة عنده

    • @mahmoudhassan6934
      @mahmoudhassan6934 9 місяців тому

      @@abdelrahmantarek7713 مصري ايوا
      كان بيخمي تجربته علي الفيس أنه بدأ يشرح كدا من ايام كان بيذاكر رمد في مصر
      وكان في ريل هنا لما كان بيتكلم عن thalathemia قال إنه مصري

  • @Abdullah10466
    @Abdullah10466 Рік тому

    Who is the famous Egyptian professor ?

  • @Dr_strange_2652
    @Dr_strange_2652 5 місяців тому

    ❤❤❤❤❤

  • @drsidhant11
    @drsidhant11 Рік тому

    could jaundice be more simplified, no! ❤

  • @dailydoseofmedicinee
    @dailydoseofmedicinee Рік тому

    🎉🎉

  • @mayflower2904
    @mayflower2904 9 місяців тому +1

    I love you

  • @abdullahalghamdi4859
    @abdullahalghamdi4859 Рік тому

    Wooooooooowwww

  • @Dr_strange_2652
    @Dr_strange_2652 5 місяців тому

    Hey perfectionalis
    Please make something easier payment system like DR.Nazeeb. as we from Bangladesh can't enroll in ur courses due to lack of credit cards.
    You can make a deal with some Bangladeshi online payment pages who help in payment...
    Please medicosis, help us in this wayyy❤❤❤

  • @Katt-w3
    @Katt-w3 Рік тому

    Hi how are you love from jess x

  • @alorosie322
    @alorosie322 10 місяців тому

    In love with you ❤

  • @stianajohn2195
    @stianajohn2195 9 місяців тому +1

    Can you reduce your subscription money . Im from India and its expensive for me

    • @tanayraj7800
      @tanayraj7800 4 місяці тому

      Just go the site and buy it from there

  • @ragaeeramzy7432
    @ragaeeramzy7432 Рік тому +1

    😅first

  • @أسامةالعوامر
    @أسامةالعوامر Рік тому

    Are you Egyptian?😅😅😅

  • @hishamabu1170
    @hishamabu1170 4 місяці тому

    ❤❤❤❤❤