Why beta blockers can save lives in septic shock

Why Use Beta Blockers in Septic Shock?
In this DigiTalk (I Expert, I Topic, I Minute), Professor Michel Slama, Chairman of Critical Care Medicine at Amiens University Hospital, France, explains the rationale behind using beta blockers in septic shock patients.
Beta-blockers are essential for several reasons:
Increased Diastolic Time:
They enhance the relaxation of the left ventricle by increasing the diastolic time.
Reduced Oxygen Consumption:
Beta-blockers decrease the heart's oxygen consumption, improving metabolic efficiency.
Cardioprotective Effects:
They offer a cardioprotective effect and have antithrombotic properties.
Restoration of Downregulation:
High levels of catecholamines lead to the downregulation of beta receptors, making stimulation less effective. Beta-blockers help restore this balance.
Anti-inflammatory Effects:
They also provide an anti-inflammatory effect.
In ICU settings, beta-blockers such as Landiolol and Esmolol are used to decrease heart rate and improve the clinical situation of patients with atrial fibrillation or excessive tachycardia.
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[@drosmankaya]

Patients with sepsis are generally hypotensive. So, giving beta blockers is a very challenging

[@MrFASSOLY1990]

waiting for guidlines update if this is truly effective