FDA Approves First Crispr Treatment for Sickle Cell Disease
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- Опубліковано 2 сер 2024
- A gene-editing therapy for sickle cell disease was approved by US regulators, a milestone for the DNA-modifying technology Crispr. Crispr Co-Inventor, 2020 Nobel Prize winner in chemistry, and Innovative Genomics Institute founder Jennifer Doudna joins Caroline Hyde and Ed Ludlow on "Bloomberg Technology."
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This is really awesome news. It's great to see people still trying & succeeding in making cures. Not just treatments.
Love Jennifer’s dedication to humanity….so very caring and knowledgeable! I truly believe medicine will be advanced in every area of human life!!
DouDNA born for this.I love her...
She is so dedicated to her work...
I love science!
just wow!
Gracias a Dios 🙏🏾encontraron este tratamiento por miles de personas q cargan ese gen en su ADN.
Totally rad
Good news dr yhank you
If you're science department has received any government funding bra.
It really belongs to the people.
Dumb
People here are shocked by the price tag. It must be remembered that all types of health care is a business before anything else
Most new tech starts out expensive and poor quality. The first cell phones cost dollars a minute, worked almost nowhere and had batteries the size of a brick that didn't last very long. Those early high prices pay for mass availability and better quality later.
Its funny, they use public funding to RND technologies like CRISPR, but somehow private companies gets to make profit by selling it back to the people.
Can it be used for Huntington's?
Lets gooo !
love ❤
Bluebird Bio all the way 🐦
wait this treatment avalible for beta thalassemia trait people?
Where's hiv cure
Hopefully not too far away from genetic modification
When it'll come to other countries?
Approved in UK, USA and Bahrain. Pending approval in Saudi Arabia. Vertex has global presence so I am sure this is going to be rolled out in all regions in the next 2 years.
@@AnirbanGhosh-eu5fm since everything works with the money agreement if some states authorize all the others authorize it for the moment it is only Canada and the United States
@@AnirbanGhosh-eu5fmsirve para curar el VIH
Es una inyección??
Can a mother carry a pregnancy after this treatment? Because it works by disabling the malfunctioning adult hemoglobin gene, leaving the good fetal hemoglobin gene to activate as a backup. But the purpose of having two versions of hemoglobin is that the fetal version binds oxygen better than the adult one, allowing the fetus to pull oxygen out of the mother’s blood.
If the mother’s blood also has the fetal version, what happens?
Good question. Yes, a woman would still be able to become pregnant and carry a fetus then deliver a healthy baby.
CRISPR edits the mutated hemoglobin gene and tells the body to produce "normal" adult and fetal hemoglobin.
@@hvqc09 Hmm, my understanding was they just break the adult gene… with the result that the fetal hemoglobin gene reactivates. But I could be wrong. Using CRISPR to make controlled substitutions is still experimental I thought.
Does it work with all people??
🤣
@6:13
wow
Omg good news thank you😂😂😂😂😂😂😂😂😂❤❤❤❤❤❤❤❤❤
Yeah, does nobody remember the beginning of I am Legend?
JD even looks similar to the female Doctor in the beginning of the movie!!!
The resemblance is uncanny 🤣 ua-cam.com/video/B3xY6Ffy_wE/v-deo.htmlfeature=shared
LOL tell me more?
Why is peoples comments hidden under your comment 😂
Why indeed...
Scifi is often cautionary but almost always imaginary and hyperbolic. We probably will die of heatstroke before the Jetsons happens
What about the remainder of the population? Do they have a right not to introduce those genes into their genepool?
If yes, how would they know with whom not to procreate?
They only modify the cells that make blood. Not the cells that make egg and sperm.
2.2 million dollars for the treatment.
A lifetime of treatment for sickle cell anemia is estimated at 1.4 - 1.8 million. I bet costs will half every few years for this treatment just like all other new technologies as they scale. In 5 years, bet it will be significantly cheaper than a lifetime of treatment and thus insurance will actually save money to cover the treatment.
Not to mention all the pain of the chemotherapy as a prerequisite and the months of being in a hospital bed.
@@U23721
Absolutely it would be cheaper within few years
Actually lifetime cost is between $4-6MM (as per CEO of Vertex) and that’s not even counting the humanistic cost of carrying this deadly disease.
@@AnirbanGhosh-eu5fm
Less than 1% patient can afford it
If every pharmaceutical company give this treatment then it would be cheaper soon
2.2 million minus the cost of diverted resources. to explain some poor dude goes into ER but all hands on deck doing a transfusion, dude in ER dies. How many? Let's compare that to the cost of one transfusion a month. Costs aren't getting any cheaper. due to inflation the cost may be higher later. Also, all the pain these poor patients go through, and they may be able to lead a normal life.
You would think diabetes would be next on a list.
Most diabetics are type II which is only partly genetic. It isn’t as directly related to genetics as sickle cell disease. Type II diabetes is more of a lifestyle disease having to do with poor diet, obesity, and low activity.
What about cancer...
@@KumariKumari-fw7nc it would be perfect for cancer since cancer is caused by DNA mutations that cause abnormally uninhibited cell replication
Y para curar el VIH???
NOOOOOOOOOOOOOOOOO NOOOOOOOOOOOOOOOOO!!!!!!
Here we go crippin virus.. I am legend in real life.
The beginning of the walking dead 😵 💀 ☠️
Nope, just science helping people live normal lives...
when your knowledge of reality comes from tv shows and movies 💀the last of us and world war z are way better btw
HIV????? SÓ BLÁ BLÁ BLÁ BLÁ BLÁ
Great job 👏
Swifties r in dire need for gene editing treatment🥹