Go Beyond RNA: Unveiling Downstream-of-Gene Transcripts (DoG RNAs)
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- Опубліковано 28 гру 2024
- Downstream-of-gene (DoG) RNAs are the RNAs transcribed continuously beyond the host gene transcription termination sites. They occur in ~10% protein coding genes in the cells, with typical sizes between 5~200 kb. Due to their extended lengths, some DoGs can further produce DoG-derived chimera RNAs and circular RNAs. DoG RNAs have many unique properties and important biological functions. They are often associated with cancers and diseases.
This webinar will cover:
• What DoG RNAs are
• DoG RNA Biogenesis
• DoG-derived chimera RNAs and circular RNAs
• DoG functions and diseases
• DoG RNA profiling and research roadmap ahead