Collin Ewald | Aging & The Extracellular Matrix
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- Опубліковано 2 жов 2024
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Collin Ewald | Aging & The Extracellular Matrix
Collin Yvès Ewald is a Swiss scientist investigating the molecular mechanisms of healthy aging. He is a molecular biologist and a professor at ETH Zurich, where he leads the Laboratory of Extracellular Matrix Regeneration.
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Amazing talk
Coro7 cytoskeleton remodeler "CORO7 is required for the activation of the Hippo pathway in response to cell-cell contact, serum deprivation, and cytoskeleton"
15:36 causal inference
23:33: OE collagen and longevity.
hemidesmosomes help coordinate muscle with others
Any information on Extracellular Matrix on Aging and vesicles between species is of interest to me !
(On Saturday of April 29, 2023). On the Matter of PhD Collin Yves Ewald (Avea Cofounder et al) And "Aging And The Extracellular Matrix (ECM)" by Foresight Institute, Host Allison Duettmann (My Babe), Via UA-cam (Google, AlphaBet Inc): 1) On the Matter of Geriatrics I am Partial to Stem Cell Therapy which was Propined herein by one of Incisive Speakers as when Fibroblast becomes Senescent or out right Necrotic and thereafter if No Acute Regenerative Activity soon Deposition Disease Ensues ie Alzheimer's Disease with Beta Amyloidosis or Tau Proteins. This Fibroblastopenia or Senescence of Homeostasis of course could be Preventative. And if I am Preferential for Hemocytoblastotherapeutics, it is even more Flagrant on the Prophylaxis side of Things (Prevention rather than Curative). 2) Therefore, Gerontology is my best Affinity topic Matter and the Aesthetics therein--Uma Boneca da Vida. When Fibrosis, Sclerosis and Pathological Deposition occur, I rather say this is the Pathology of Degeneration Disease. Not only is there the Age-Related Paresis of all systems of the Body but so is there Cytopenia of the sort that makes sense to Cultivate, I really not caring herein if this becomes Systematized Medicine in the Respect only and only when it becomes Prophylaxis Therapy rather than End-Stage Disease Stages. 3) I due to this Lovely Expose on Extracellular Matrix (ECM) undertook a basic Internet Search on Lifespan Extension (LE) Chemicals and somewhere usual and Expected i.e. Flavonoids, And Vitamin C for the typical Antioxidation Mechanism therein. But some others that were Positive on Caenorhabditis elegans (C. elegans) Nematode were shocking and rather unexpected: 1) Aspirin (NSAID) with 50-100% LE, Zidovudine (Retrovir Tradename), an HIV-AIDS Antiviral with Nucleoside Reverse Transcriptase Inhibition Drug Class Modality and Mechanism of Action (MOA). and Atracuriam, an Anticholinergic and/or Muscle Relaxant Drug Class. I do not know what these have that is Relevant to all other Patients or Species in the matter of Possible Repurposing these Chemotherapeutics. I just did not hear anything herein about such as Chondroitin Sulfate and Glucosamine which I personally analysis in Vivo autodidactically. Anyway Prost. Lovely, work out there in the Swiss Alps, perhaps it is the Environment that makes enjoyable People as Longevous Creature too. Herr PhD Ewald, es geht hier gut aber wir mussen verschnellen was haetten sollten geschah in der Gangenheit lang beivor. Sollten alle Die haben die Gesundheit und Freide Immer mal. Heil!