Re-writing the Code of Life: CRISPR Systems and Applications of Gene Editing

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  • Опубліковано 8 січ 2025

КОМЕНТАРІ • 93

  • @donross7820
    @donross7820 5 років тому +12

    Jennifer is such a superb educator and lucid speaker! Thank you so much for this talk. I am currently making animations of CRISPR Cas9 using Cinema 4D, ePMV plug-in, and the PDB and I can rotate in 3D the gorgeous CAS9 enzyme complex, remove just the sgRNA or just the DNA, etc. I am in molecular biology Nirvana. This lecture gives me the understanding of what is happening with the conformational changes and such.

  • @FranckDernoncourt
    @FranckDernoncourt 5 років тому +17

    Lecture starts at 7:22

    • @ouimetco
      @ouimetco 4 роки тому

      Thank you

    • @tiewei1614
      @tiewei1614 3 роки тому

      呃呃呃呃呃呃呃特呃呃呃呃呃呃呃哈哈哈🦢🦢瑟瑟二胎呃呃呃呃额特恶呃呃呃呃呃呃得瑟🦢🦢呃呃俄而他呃呃呃e e e e e e e

    • @tiewei1614
      @tiewei1614 3 роки тому

      🦢得瑟儿儿饿饿特呃呃呃呃呃呃呃呃呃呃呃呃铽尔尔🦢呃呃呃呃呃呃呃呃呃特尔尔e

    • @tiewei1614
      @tiewei1614 3 роки тому +1

      🦢尔尔呃呃瑟瑟🦢呃呃呃呃呃呃呃呃呃呃呃呃呃呃呃呃呃呃呃呃饿的🦢二二🦢呃呃瑟瑟二二饿的二二呃呃饿的🦢呃呃饿的🦢呃呃呃瑟瑟呃呃饿的俄而呃呃呃呃呃哈哈哈二二🦢二二二二二二🦢🦢🦢🦢二二呃呃呃热的水二二🦢🦢嗯嗯呃呃饿的呃呃呃呃呃呃呃呃而呃呃呃呃呃呃🦢🦢呃呃呃特呃呃呃呃呃呃呃呃呃热的🦢瑟瑟瑟瑟嗯嗯嗯嗯特色🦢呃呃饿的嗯嗯俄铽嗯嗯瑟瑟瑟瑟饿而呃呃呃呃呃呃呃而呃呃呃呃呃呃🦢嗯嗯e e te

    • @tiewei1614
      @tiewei1614 3 роки тому

      @@ouimetco 瑟瑟嗯嗯呃呃饿的🦢🦢呃呃饿的🦢呃呃呃呃特呃呃呃呃呃呃而呃呃呃呃呃呃呃呃呃特呃呃饿的🦢🦢瑟瑟🦢

  • @__________6597
    @__________6597 3 роки тому +1

    Is possibile build nanotecnology medicine for kill cancer or infections? Tx

  • @timothybucky7170
    @timothybucky7170 6 років тому +1

    people make up their own minds. important to all of us as well as to themselves.

  • @Pyriphlegeton
    @Pyriphlegeton 4 роки тому +1

    45:10
    Talking about applications

  • @MadameCorgi
    @MadameCorgi Рік тому

    Molecular mechanics of Cas9 function remain to be fully understood.
    Dna/rna hybridisation efficiency cas9 can bond dna and not cut it - - >HNH domain
    How is Cas9 activity powered?
    Target strain impacts binding kinetics and catalytic activity

  • @timothybucky7170
    @timothybucky7170 6 років тому +1

    the mission statement in this endowed lecture is faithfully carried out in that we have the elucidation of locomotion without the requisite energy and more instruction then molecular affinity. one of these characters is called a walker as it locomotes down a strand. animation does not simulacrum but it does demonstrate locomotion as it is done at this size.

    • @joedart8449
      @joedart8449 6 років тому +1

      Gosh I wish I could understand the point of this effete comment. For example "locomotion without the requisite energy" is not what she said. She said that the regular ATP battery was not involved, but that the energy is supplied by some other means, perhaps mechanical. Imagine a scissors driven by Brownian motion. There's a lot of pushing and shoving between these monster molecules, it's not hard to imagine some of them getting "wound up" potential energy in the jostling and later unwinding to cleave the DNA.

    • @timothybucky7170
      @timothybucky7170 6 років тому

      how complex is what is needed to work at this the scale where one can only imagine simple operating. will we ever be a player in this world that outclasses us.

  • @drbravinderreddy
    @drbravinderreddy 4 роки тому +1

    Absolutely amazing!!

  • @rubycosta3578
    @rubycosta3578 2 роки тому

    O QUE PENSARÁ DEUS SOBRE TAL?!?!

  • @SaidulIslam-nw8sg
    @SaidulIslam-nw8sg 4 роки тому

    Thank you so much ❤️❤️❣️

  • @nermeenabdelmoez6347
    @nermeenabdelmoez6347 5 років тому

    Great!

  • @BLMCFR
    @BLMCFR 2 роки тому

    Would you like to know 1) The conditions, the events, and the processes at the DNA level for how multicellular complex life emerged on Earth about 550 Million years ago, and 2) Additional factors for how life emerged on Earth about 3.8 to 4 Billion years ago??
    I have these answers verified with 95% empirical evidence.

  • @abooswalehmosafeer173
    @abooswalehmosafeer173 3 роки тому +1

    What is even a gene?
    And what is Cell?
    And DNA?
    And an Atom?
    What is the most microscopic?
    And the Biggest?
    I am in a Vortex!
    Curiosity easy,but comprehension not Gifted to Me.
    Despair and Despondency!
    My Tomb is watching me,almost grimacing in mock.
    Humility.

  • @nollypelobueno7589
    @nollypelobueno7589 3 роки тому +4

    God create human,do nt change and that sin.

    • @stilettoczar678
      @stilettoczar678 3 роки тому

      Exactly!! There are many little g “gods” following the original copycat, lucifer, but we have only one TRUE Creator...THE God of the universe!

    • @BLMCFR
      @BLMCFR 2 роки тому

      No, God gave us the knowledge and technologies to undo the damages Lucifer has done through diseases.

  • @gmailfarmer2779
    @gmailfarmer2779 3 роки тому

    The special fly densply squeeze because sandra electrophysiologically press lest a painstaking nut. modern, numberless skill

  • @chintusct5258
    @chintusct5258 4 роки тому +1

    any Indians?

    • @woloabel
      @woloabel 4 роки тому

      ....But can play one....

  • @KoDeMondo
    @KoDeMondo 2 роки тому +1

    Oh Jesus when science PLAYING being God

  • @bodgertime
    @bodgertime 4 роки тому

    I have to laugh when she says cartoon. Bacteria can handle viruses. So can eukaryotic cells absorb bacteria's cell functionality ?

  • @benblay9205
    @benblay9205 2 роки тому

    This is not amazing. It is evil. This is from the devil.

    • @BLMCFR
      @BLMCFR 2 роки тому

      Then why did God give us the knowledge??

    • @benblay9205
      @benblay9205 2 роки тому

      @@BLMCFR Knowledge was giving to us because we are the image of GOD. But sin corrupted it.

    • @BLMCFR
      @BLMCFR 2 роки тому

      @@benblay9205 You are talking generically. I am talking specifically. I have discovered new information for DNA. This is not from the devil. God gave me the knowledge. I am hoping to publish the information in science and medical journals for all to read as soon as I verify a few details.

    • @benblay9205
      @benblay9205 2 роки тому

      This is not what we learn from books. The video that you are defending is not the works of men. So I hope you stay in prayers and know what is going on. I know also that,sometimes,that science work, but this time science is on the dark side of the evil. Pray to the LORD Jesus Christ for insight, and don't trust science this time. Thank you.

    • @rachaelfleming7132
      @rachaelfleming7132 2 роки тому

      @@benblay9205 we are not gods nor do we become gods thos has grossly been misunderstood by those for those that are narcissistic in character...
      We were gifted love in our hearts in the likeness of the original loving creator to know within our hearts what is of good kindness respectful caring and understanding so there would be good sound decisions and actions that preserves and caretakes of all we were lovingly given basically to know what is destructive and to know when to stop or not to proceed with projects that only are for narcissistic purposes intent and agendas that will favour some over others in riches glory self entitlenents that cause harm genocides stolen lands or taking more than needed leaving people withput food clean water or healthy air to breathe ...common sense to know what is of good and what is not ...and the narcissistic character traits of those that think they are gods is unstable and very dangerous they may be intelligent but are not wise or loving ....please remember the love given and that the alchemical narcissistic intent and agendas are of unstable minds that know not what is good ....wisdom is to know when to stop!