Penicillins: Acid sensitivity, Beta-lactamase sensitivity and spectrum of activity

This video discusses the problems with penicillins including: Acid sensitivity, Beta-lactamase-sensitivity & Narrow spectrum of activity, and how to overcome them in order to have penicillins with better activity and stability.
Thank you

[@Peach-zc4sy]

Oh my god, I finally found a helpful video to solve my huge problems with understanding the acid sensitivity of penicillin. Thank you so much.

[@pharmacyEd]

Very glad to hear this. You are most welcome!!

[@ranamk6534]

better than my doctor

[@samuelgege2270]

Very informative and straight to the point!

[@musakoroma6966]

Oh my gosh I'm loving it. Medicinal chemistry

[@pharmacyEd]

I am glad to hear that ♡

[@michealphiri9383]

Thank you for your time. I appreciate

[@pharmacyEd]

You are most welcome

[@Abdullah_bataineh]

This is the best video explaining it simply… loads of thanks

[@pharmacyEd]

Glad you liked it!

[@EmanMohamed-hj8xn]

Thank you so much this really helped me with my exams♥️♥️♥️♥️♥️

[@pharmacyEd]

You are most welcome!
I’m very glad to hear this.

[@jesshanwell349]

This was incredibly helpful, thannnk u

[@nour7974]

Great video

[@pharmacyEd]

Thank you

[@user-xr2qb5nk1t]

Thank you!! lifesaver ❤

[@beshoyroston9267]

Thank u ,This was very helpful .
I hope u make one about cephalosporin.

[@pharmacyEd]

Sure, I will.

[@manarahmad906]

Super helpful indeed! Thank you for your time and the great effort

[@pharmacyEd]

Thank you for your generous feedback!

[@mohammedal-any5061]

Thank you so much ,simple,great

[@pharmacyEd]

You are welcome!

[@olaajayi6629]

You just saved a life!! Mine. Thanks a lot.

[@pharmacyEd]

Oh that means the world to me. Thank you

[@olaajayi6629]

@@pharmacyEd Thank you! I passed. ❤️

[@mohamedtariq9313]

Thank youuuu❤❤❤❤❤

[@chloenguhy]

thank you so much!

[@pharmacyEd]

Most welcome!

[@a7mad-525]

Thank you so much

[@pharmacyEd]

Most welcome!

[@paulinekiden4436]

Thank you so much👏👏👏👏

[@pharmacyEd]

You are welcome!

[@shouqk5335]

Literally thank you ! it is completely helpful ❤❤!!

[@pharmacyEd]

Most welcome!!

[@danaha1062]

Can you make more video about medicinal chemistry cause it amazing !!!

[@pharmacyEd]

Sure, any specific topic you request?

[@danaha1062]

Could you make.Video about carbapenem and monobactam ?

[@pharmacyEd]

Sure, soon will make it.

[@aminagul-zo4tj]

amazing video, thankkk you u made my life easier ❤

[@pharmacyEd]

You're welcome 😊

[@user-gt9di5vw2n]

This is greaat

[@user-ld8uq7xj5e]

I am quite confused here. How can the addition of the EWG withdraws the electron from the carbonyl carbon oxygen again? Thank you

[@pharmacyEd]

Ok, the EWG as the name suggest has the ability to withdraw electrons from atoms rich in electrons like the oxygen in the carbonyl group, when they take away the oxygen’s electrons, oxygen become deficient in electron ( lost its power ) therefore it will not be able to attack the carbon in the amide group ( inside the lactam ring), hence the effect of neighboring group on breaking & deactivating the b-lactam is minimized. I hope its clear for u now

[@RevulsionX]

as easy as drink water, thx 🙏🙏

[@pharmacyEd]

Glad to hear that :)

[@yunhajin7346]

Can't thank you enough, this is really better than my instructor's explanation u saved me 🤍

[@pharmacyEd]

You are welcome!