Macrophages: The Destroyers
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- Опубліковано 12 вер 2023
- Before we move on from the innate immune system, let's go through all the cell types one by one, so that we can better understand them. Let's start with macrophages, which are long-lived phagocytic cells. They play a pivotal role in recognition, phagocytosis, and degradation of cellular debris and pathogens. Let's learn more about them now!
Script by Niyati Vachharajani
Select images provided by BioRender.com
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As a graduate student researching these cell types, excellent job making this video Dave!
Finally. I get actual knowledge about macrophages.
Frfr never trust kurzgesagt
@@Teqnifiiwhy? Im not contrary, just curious why
@@alexvonrom7942 funded by millionaires looking for investors
@@Teqnifiiwhy? Dave is university lvl. Kurg is for total laymen. Him and his team have to dumb it down. Dave is good at teaching and your probably not a total layman. Also Dave hires folks as needed. It is the difference of entertainment vs educational. While both are both they focus on slightly different points. In a nut shell, Dave's focus is helping students understand the information. Kurgs focus is helping young and layman understand via fun videos. Wile both are entertaining and educational the detail isn't the same
@@borttorbbq2556 as I say, Kurg is funded by millionaires, so they're going to emphasize anything that drives up hype surrounding products and treatments that investors peddle. I phrased it a little strongly, obviously they're not going to make shit up, but the grain of salt required to watch Kurg is significant enough to merit at least a follow-through internet search.
I always appreciate how clear and easy to understand these videos are. ❤
I think this raises an important point, look how many cells are required for many lives to be lived and they all help us in some way or another and I think this also reflects our social lives as well. We all serve some purpose in society, while that purpose maybe negative in some they still do it and I think it tells us that we need to become immune to our own social problems.
"We all serve some purpose in society"
I can't agree with that. We might all have a role we play, but that does not mean we have a purpose.
I have been relieved of the ambiguity of the knowledge of macrophage which I have been struggling to understand. Thank you Professor Dav. Now I can comprehend my lectures slide.
Great video as usual Dave!
Please prioritize your immunology course over others right now. It’s great content
Thank you for all your videos. they are very informative, clear & simple ❤❤
Professor Dave 🚀🚀
Wait, are you dropping more immunology stuff? Please do, I'm a med student and have a test soon. You're the man, Professor.
Yep there's about 14 more after this, not all finished though
@@ProfessorDaveExplains Please upload them when you get a chance. I’d really appreciate it. Trying to binge before my exam 🙏🏼
Please consider coving more medicine topics (human physiology, pathophysiology, etc). Your graphics, way of explaining, and efficiency are unparalleled. Thanks again!
i have more pharmacology coming as well
hooray! immunology! this is one of my favorite topics.
This will be fun! 😊
Wooo, macrophages! One of my favorite cells! /nerd
Macrophages are also responsible for the permanence of tattoos. The ones residing in the skin eat the ink particles and that's why they don't get flushed out of the body.
Your pronunciation of "phagocytic" had me on edge 😂
Oh, hey! The cytokine GM-CSF is related to one of my responsibilities at work. I would like to know more about what increasing levels of anti-cytokine antibodies in serum indicates; did you come across anything while producing this video that you could recommend?
Professor thanks for video, however you missed one the most advanced targets on M2 macrophages, which is the mannose receptor CD206. Early in the video you mentioned carbohydrates, but failed to carry through identifying CD206 C-type lectin, primarily present on the surface of macrophages and immature dendritic cells, which will internalize mannose (carbohydrates) delivered using a dextrin spine/backbone, mannose moiety and a Dx radioph or Thx payload like doxy, which is really important in TAMS and other inflammations to minimize offsite toxicity, etc
Aw, come on. They’re both ever-so-captivating! 🙂
What types of halogenation reactions do they use?
It's a sad day when Dave doesn't have any funny quips for the pre-intro
Macrophages are the coolest thing we have. I think of them as the Star Destroyers of our immune system.
Cells at Work portray them as Giant maids wielding large weapons
Will you go over monocyte?
Monocytes*
I watch your videos to help remind myself that I am incredibly ignorant of most of the topics you present, regardless of my frequent consumption of science related content. Please, don't ever make these videos dumbed down to the layman level, as that type of explanation suggests that our understanding of complex things is just something some people figured out, instead of the obvious building knowledge upon knowledge that the learned and determined intelligent minds have worked to understand our world.
How's that song go? "Despite all my rage, I'm still just a macro-phage" :)
❤
👍💥
👍🙂
Ara ara~
We love her❤
Cool Sci Fi B movie title.
6:37
I love you😂❤❤❤❤
Isnt it a weird and wonderful planet.
Let me guess.
The 2 hidden videos are about a certain thing that was happening for about 2 years?
Um, no.
This one lost me. Biologist not my area beyond grade 10 level science. I did watch the whole thing though 😁
Absolutely mindblowing. ❤🙏😑 God is the greatest engineer of all time.
Don christie?!
Hey dude
@@donchristie420 the class started an hour ago, you're late 😅
@@waelfadlallah8939 was here- you not and got busy before could ask for you
@@donchristie420 always 2 steps ahead, that's my Don right there 👍
The diagrams make no sense to me.
Lol he said phag
Can you respond to creationist named eyad qunabi
He is a Muslim Arabic creationist, and he has over 2 million subscribers
Dr. James Tour is your daddy!!!
i doubt jimbo even understands how reproduction works, given how CLUELESS he is about biology in general.
Um, then how did I humiliate him so badly?
@ProfessorDaveExplains Your intelligence was exposed when you got backed against a corner, and all you resorted to was disrespectful name calling and noises!! You're an infant in the science world and have much to improve on, including your scientific view.