Mammalian Pyridoxine (Vitamin B6) Processing & Metabolism
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- Опубліковано 13 кві 2019
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the Best video on B6 Metabolism. Thank you very much!
Just one Question: B6 is absorbed by the jejunum, but where does this reactions occur?
Great video, very clear. Thank you! Please keep them coming!
Would 10mg of pyridoxine increase dopamine?
Excellent video. Question -- I am aware that B6 is a water soluble vitamin. Is there a reason WHY someone will have Vitamin B6 toxicity --? --- Without taken large doses of B6.
I see H2O2 is produced in two of the pathways. Maybe not consuming as much pyridoxal and more of the other two is an issue if your catalase isn’t that effective?
Just been looking things up - “it appears that the inactive form of B6, pyridoxine, competitively inhibits the active vitamin B6 form, pyridoxal-5’-phosphate causing the symptoms of vitamin B6 toxicity to mimic the symptoms of vitamin B6 deficiency.”
@@AntimatterBeam8954 I have done my share of looking into things as well. Yes, the Vitamin B6 can NOT get into the cell due to the MTHFR gene. Due to the SHMT gene --- it is the 'b-side that no one really looks into'.
@@thejdocrealminute4648 that’s intriguing - I’ll have a look on that point too - the SHMT gene I have heard of but not looked into too deeply. Thank you! If I have anything I will share back.
@@AntimatterBeam8954 Thank you. It is more involved 'indirectly'. It is not a direct pathway to the same mechanism of B9/12 is. BECAUSE --- it is not a direct pathway....there is little to be known.