Chromosomes and Karyotypes
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- Опубліковано 20 тра 2024
- Explore chromosomes and karyotypes with the Amoeba Sisters! This video explains chromosome structure, how chromosomes are counted, why chromosomes are important, and how they can be arranged in a karyotype! This video also tackles a few misconceptions about how chromosomes.
Table of Contents:
00:00 Intro
1:15 What makes up a chromosome?
2:18 Understanding replicated vs. unreplicated chromosome
3:28 Introducing a Karyotype
4:01 Potential Misconception with Karyotype
5:28 XX and XY Chromosomes
* As we mention in our video about Punnett squares with sex-linked traits, we want to add this here too: there is more detail to sex determination than just sex chromosomes and more combinations possible than XX and XY combinations. We have some further reading links you can check out linked in the other video and we also want to paste in some of the examples from that description here:
XXY: www.genome.gov/Genetic-Disord...
XYY: medlineplus.gov/genetics/cond...
X: www.genome.gov/Genetic-Disord...
Info about SRY gene & also conditions related to variants in SRY gene:
medlineplus.gov/genetics/gene...
Vocabulary includes chromosome, centromere, sister chromatids, chromatin, nucleosome, haploid, diploid, homologous chromosomes, gametes, autosomes, and sex chromosomes!
Reference: OpenStax, Biology. OpenStax CNX. Mar 21, 2018 cnx.org/contents/185cbf87-c72e....
Special thanks to Dr. Brian Davis for his expertise in verifying that a typical karyotype would show 2 chromatids per chromosome. (This has been a misconception we've seen in the classroom from many diagrams)
A real life karyotype from NIH (in public domain) commons.wikimedia.org/wiki/Fi... can be excellent for viewing alongside this video.
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Hindi Subtitles Credit: Alisha Aggarwal
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We make pinned comments for clarifications or corrections. Some updated versions of textbooks are using a more detailed definition of molecular sequences making up the centromere - which means that when you have a chromosome with replicated chromatids - you could consider it to have two centromeres (one per sister chromatid) although they are bound together in a region. Many textbooks still refer to a single centromere on a chromosome with two fully attached sister chromatids - as they are considering the complex where the centromeres are attached - and then they show fully separated sister chromatids with their own centromere. While we have done this as well by illustrating one centromere per eukaryotic chromosome, we think it is important to understand this complex is where they are joined with cohesin in the case of sister chromatids - as well as also understanding how the definition of centromere has changed. You can see a conversation about this here: twitter.com/AmoebaSisters/status/1192621868605419520 It would have been better for us to have said "centromere region" - and again, when sister chromatids are attached at the centromere region, it is still counted as one chromosome. If we update this video, we'll probably feature this information about the centromere and we'd like to improve our drawing to show the bound centromeres.
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Other things to note: just as we mention in our video about Punnett squares with sex-linked traits, we want to add this here too: there is more detail to sex determination than just sex chromosomes and more combinations possible than XX and XY combinations. We have some further reading links you can check out linked in the other video and we also want to paste in some of the examples from that description here:
XXY: www.genome.gov/Genetic-Disorders/Klinefelter-Syndrome
XYY: medlineplus.gov/genetics/condition/47xyy-syndrome/
X: www.genome.gov/Genetic-Disorders/Turner-Syndrome
Info about SRY gene & also conditions related to variants in SRY gene:
medlineplus.gov/genetics/gene/sry/
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We appreciate the comment that there was a point in the video where one of our chromosomes had sister chromatids that didn't match in our illustration! It has been corrected. (Sister chromatids should be identical)
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This is not our only playlist about chromosomes- we have a heredity playlist here! ua-cam.com/play/PLwL0Myd7Dk1FVxYPO_bVbk8oOD5EZ2o5W.html Also, you can find resources that go with our videos here www.amoebasisters.com/handouts
Did you guys fix the video ? I can't see any difference (except the highlight) in those chromatids .
I love your videos but i have to keep pausing and rewinding to think because it's too fast.😥
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My teacher makes his salary off these videos
butter than having salary while she/he is setting in the chair
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Especially now bro since quarantine
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@@ashwikasingh4967 same
class 10th boards
And ninja nerdddd
When a 7-minute youtube video teaches you more than your teacher can in 50 minutes
Facts
Not 50 minutes, make it 2 months
fr
perhaps you didn't listen in those 50 minutes. I use these videos in class often. But there is no denying that students don't always pay attention in class. Many of my students love these videos, and many have asked me not to show them as they understand my way of explaining better - I now use both formats to hopefully reach more students.
Stating the truth there
I am a 5th year medical student .. karyotyping was always confusing me ..and i was so shy to ask my professors ...thank u for clarifying this
So then maybe you can help clarify it to me... a karyotype is the shape of the chromosomes or how they look?
@@badenclosson8195 A karyotype is a chart that shows the number and visual appearance of the chromosomes in the cell nuclei of an organism or species.
@@badenclosson8195 so you would need a karyotype - for example - to confirm that you had a trisomy, or maybe a monosomy or things like that, also to check for other types of mutations
Is it important to study cytology in medical?
shouldve got it down by 9th grade freshman year, like i did. *smirks
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Tessa SAME
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Ikr!
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I have been struggling with the whole cell phase in general and genetics with chromosomes and Karyotypes. Your videos have helped me so much this semester because you easily explain everything in a very simplistic way that makes sense and is clear to understand! I am so grateful for you guys, thank you so much for your amazing videos!
I have a final today. These videos have helped me immensely to gain an idea of what’s going on, then my required readings make more sense than they would had I not found this channel. The drawings are also great. Thank you.
Thank you SOOO much for this!!! I have literally spend my entire life trying to figure out why two sister chromatids are still a chromosome, and you explained it so simply. These videos are the best!
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I already knew all of this, but I'm gonna compliment on a very good video! Very easy to understand explanations about how all of this works and how to understand it, that someone who didn't know much about it before could follow along. A perfect video to show kids in school, and from the comments it looks like plenty of teachers have!
Everyone of these videos I watch, I always write new ones down. Thank you, amoeba sisters!😊
i love the way u share ur stories with us, and it makes me happy we both had the same misconceptions. plus the way u teach is so enthusiastic. u don't sound dead or like a robot and speak really slowly and it helps me process the informations. sending lots of love :)
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Great work Ma'am! After spending more than 4 days on internet I found this kind of video exactly explaining my queries. Thanks a ton! I thought only I was having these kind of doubts regarding no. of chromatids during metaphase and issues with 2n chromosome. This become further difficult to understand when you are not a bio student. Excellent work again! Thanks a lot!
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Thank you!!! This really helped to clear up a lot of confusion about chromosome shape.
Thank you! You hit all of the things that have confused me throughout my biology classes (like when things are called chromosomes vs. chromatids)!
I'm a teacher and this video made me so happy. Really appreciate all the hard work you've put here to give quality education to all students of biology :-)
Thank you for these videos Amoeba Sisters! They really help me with my Biology Class. 😊
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you are trully incredible, i am sure that almost 90% of students dont undestand de graphic of the karyotype because the problem on the counting of chromosomes, you have clear a doubt that i have had for years, thanks
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When a video teaches you more than your teacher does
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Amazingly explained chromosomes and how they are counted! Thanks so much!
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THANK YOU x 1 000 000 for addressing the annoying tendency of showing chromosomes only as they exist after DNA replication and not how they are "most of the time" in the cell. Thank you for all your excellent video content.
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thank you so much for this video..... I have been always confused about chromosomes for years..Our teacher don't pick up common misconceptions...but you did..It was really helpful !!! :)))))
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(/cries)
Anyway, cool video, loved it!
This is the video I really need to solve my problem. I was sooooo confused about the numbers of chromosomes. But one thing I'd like to add is the reason after the duplicated chromosome is still consided one chromosome is because it still contains only one set of infomation. ( read it from our textbook.) Thanks Amoeba Sisters. This really helps
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Thankuuuuuuu , for so long I was confused between chromatids & chromosomes 🙏🙏🙏
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ugh thank you. I was so confused why karyotypes only showed one chromatid!!
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Finally someone explains to me why even though GNA is double in quantity, the number of chromosomes is the same! In my book, one might think that chromosomes are always double. Now I know that they can be single and now I understand! Thanks!
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