Ribonucleotide Reductase - Reaction, Regulation, Inhibitors

Ribonucleotide reductase is such an important enzyme which converts ribose sugar to deoxyribose sugar. This makes DNA synthesis possible. DNA needs deoxyribose sugars and these deoxyribose sugars will come from the reduction of 2nd carbon hydroxyl group of ribose into deoxyribose. This type of reduction is done by ribonucleotide reductase enzyme. This video also covers the mechanism of ribonucleotide reductase, regulation of ribonucleotide reductase, substrate requirements of ribonucleotide reductase reaction and also inhibitors of ribonucleotide reductase.
iI you prefer white board teaching, you may also take a look at my other video on the same topic but explanation using a white board.
• Ribonucleotide reducta...
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[@DuyNguyen-qv3pi]

THANK YOU. this is all I need for now. I just so confused before. Thanks sir.

[@chiekohoki]

Thank you so much for this, it cleared a lot of things up for me!

[@priyadsouza3955]

Thank you Dr.Prakash..very interesting vedio!!

[@DrMungli]

Thank you Dr Priya..In this video, I was more excited about teaching regulation of ribonucleotide reductase.

[@archieducation]

Thanku so much Sir 🙏

[@donyanaseri715]

very clear and concise, thank you.

[@DrMungli]

Thank you for the feedback. Appreciated ☺️

[@iykyk1749]

6:20 allosteric regulation

[@ishikasharma4613]

Amazing explanation sir thank you

[@livebiochemistry]

Nice sir

[@DrMungli]

Thank you and Keep watching

[@growingyouth347]

thankyou so much sir i love you

[@satyanarayandash4200]

Bhala Kahuchanti Odia Re Kahile Auu Tk Bhala Heithanta...

[@DrMungli]

Could not understand what is written in Odia language. It would be helpful if someone translates it for me!

[@martinaft2258]

Thanks you very much sir

[@maryamalbrazi3291]

Thank you, great explanation 🙏🏻

[@revanthjosh6925]

Thank you sir ❤

[@DrMungli]

Most welcome

[@revanthjosh6925]

@@DrMungli sir if ATP is not removed from regulatory site , how dCTP formation 'll be stopped , and dUDP binds to active site

[@DrMungli]

@@revanthjosh6925 CDP and UDP binds to active site while ATP is there at the regulatory site.. so when CDP becomes dCDP when it comes out then UDP binds to active site which then converts to dUDP, which becomes dUMP >dTMP>dTDP>dTTP which then go and replace ATP at the regulatory site.

[@revanthjosh6925]

@@DrMungli Thank you sir

[@sarahbelden646]

THANK YOU!

[@DrMungli]

Ur welcome ☺️

[@ribkaabera5164]

Tnxs