SIRT6: What We Can Learn From Centenarians | Prof Paul Robbins Ep 4

Поділитися
Вставка
  • Опубліковано 28 жов 2024

КОМЕНТАРІ • 30

  • @ModernHealthspan
    @ModernHealthspan  2 роки тому +1

    If you would like to support our channel, we’d love a coffee ☕…thank you! www.buymeacoffee.com/mhealthspan
    DoNotAge 10% Sirt6 activator - Code MODERNHEALTHSPAN donotage.org/products/sirtuin-6-activator/
    Renue By Science 10% of all products: tinyurl.com/2c28d6er
    ProHealth Supplements 10% Discount: www.prohealthlongevity.com/discount/MODERN
    Bulletproof 15% off with coupon code: HEALTHSPAN15: bulletproof.fdf2.net/c/3176409/551222/9221

  • @peterz53
    @peterz53 2 роки тому +9

    Vera, in a talk given in March, has mentioned that fucoidin (from certain seaweeds) appears to upregulate SIRT6. Mouse experiment shows that fucoidin reduced frailty in male and females after two months of ingestion.

  • @walterbates1654
    @walterbates1654 2 роки тому

    Feeding the UA-cam algorithm. Great video. I appreciate it.

  • @rogerreich2721
    @rogerreich2721 2 роки тому +6

    What is the best SIRT 6 activator supplement (DoNotAge)? Can foods suffice? This seems like an important development.

    • @ModernHealthspan
      @ModernHealthspan  2 роки тому +1

      Hi Roger, thanks for the question and I agree that identifying a good SIRT6 activator would be great. Prof Cohen's company is aiming to do this, and Prof Robbins said that he had found a compound that would mimic the centenarians but needed to characterize it better before announcing what it is. Prof Gorbunova has said that fucoidin (the active ingredient in a kind of sea algae and in the DoNotAge product) upregulates SIRT6. So there does seem to be progress in this area but there is a lot more to find out.

  • @mesosuavee5498
    @mesosuavee5498 2 роки тому +11

    Black elderberry has the highest concentration of SIRT6 activating chemicals (cyanidin). Make sure to eat the cooked form or the abstract. Do not eat it raw.

    • @mesosuavee5498
      @mesosuavee5498 2 роки тому +2

      *extract

    • @ModernHealthspan
      @ModernHealthspan  2 роки тому +2

      Hi thanks for sharing. It did have a the largest effect in vitro I think. I am curious as to why cooked is better.

    • @mesosuavee5498
      @mesosuavee5498 2 роки тому +3

      @@ModernHealthspan Uncooked is poisonous, unfortunately.

    • @ChillFantasticFive
      @ChillFantasticFive 2 роки тому +3

      @@mesosuavee5498 Dr Gregor found this out the hard way.

  • @abrahamnorthhampton3327
    @abrahamnorthhampton3327 2 роки тому +2

    I need to go back and review the Vera Gorbunova interview series!

    • @peterz53
      @peterz53 2 роки тому +2

      See her March talk on the NUS Medicine channel.

    • @abrahamnorthhampton3327
      @abrahamnorthhampton3327 2 роки тому +1

      @@peterz53 I'll check that out too, but Richard had a good interview with her less than a year ago on this channel.

    • @peterz53
      @peterz53 2 роки тому +2

      @@abrahamnorthhampton3327 He does, and that's worthwhile too. Hopefully some of his guests like Vera will come back after a year or two for updates..

    • @ModernHealthspan
      @ModernHealthspan  2 роки тому +2

      Hi Abraham, thanks. We did talk about SIRT6 at the time, in episode 4. I would dive into more detail on SIRT6 now. In some ways the field is moving quickly!

  • @sharapovam.3329
    @sharapovam.3329 2 роки тому

    Thank you, your videos and interviews are very informative!

  • @KenOtwell
    @KenOtwell 2 роки тому +7

    Ask him if the DO NOT AGE sirt 6 supplement is valid.

    • @ModernHealthspan
      @ModernHealthspan  2 роки тому +1

      Hi Ken, thanks for the comment. Prof Cohen did touch on algae as an activator of SIRT6. I do not ask guests about their opinion on specific products.

  • @SebastianNiemann
    @SebastianNiemann 2 роки тому

    Hi Richard, thanks a lot for your great interviews! One question: do you also use the SIRT6 activator? What are your experiences?

  • @ronm6585
    @ronm6585 2 роки тому

    Thanks Richard.

  • @olyav5819
    @olyav5819 2 роки тому +1

    Would be interesting to have Vera on your podcast. Wonder if she is taking SIRT6 supplements herself and if it indeed too estrogenic.

    • @rodneymarion301
      @rodneymarion301 2 роки тому

      Yes. This is interesting. I'd like to know the answer as well.

    • @ModernHealthspan
      @ModernHealthspan  2 роки тому

      Hi Olya, thanks for the question and suggestion. We spoke with Prof Gorbunova about a year ago. She is certainly someone I would love to have back on the channel.

  • @bobjohnston7347
    @bobjohnston7347 2 роки тому

    Solutions?

  • @bob-ss4wx
    @bob-ss4wx 2 роки тому

    What is the reason you can't mention the drugs?

    • @ModernHealthspan
      @ModernHealthspan  2 роки тому +2

      Hi Bob, thanks for the question. Prof Robbins said that the compound that he had identified was available over the counter but he did not want people to start taking it until it was better understood.

  • @christopherellis2663
    @christopherellis2663 2 роки тому +1

    American "drugs";
    English "medicines, treatments"

  • @bob-ss4wx
    @bob-ss4wx 2 роки тому

    In the new medicine model we don't have to wait 10 years for anything to be developed!

    • @ModernHealthspan
      @ModernHealthspan  2 роки тому

      Hi Bob, Thanks for the comment. That is what I like about Prof Robbins approach, it seems like it may have shorter term applicability than some of the others.