Gary Brecka Says Stop Picking on Cholesterol! | What the Fitness | Biolayne

Поділитися
Вставка
  • Опубліковано 10 лис 2022
  • LDL Cholesterol is an independent risk factor for cardiovascular disease: www.sciencedirect.com/science...
    Get my research review REPS:
    biolayne.com/REPS
    Get my new nutrition coaching app, Carbon Diet Coach: onelink.to/9h4d62
    My research based supplements: www.outworknutrition.com
    Get my books on how to lose fat: www.biolaynestore.com
    Take my online course "The Science of Nutrition": chfi.click/laynenorton_online
    Get Custom Workouts by me for $12.99/month:
    biolayne.com/workout-builder/
    / laynenorton
    / biolayne
    / biolayne

КОМЕНТАРІ • 463

  • @jonnysimons8530
    @jonnysimons8530 Рік тому +52

    Your videos make me feel so smart. Thank you for what you do Layne. It’s nice to have a sane voice in the fitness industry to listen to

  • @Deciden0w.
    @Deciden0w. 6 місяців тому +3

    Great break down Layne! Solid explanation. Thank you

  • @abbiec6057
    @abbiec6057 Рік тому

    Love it! Thanks Layne! 💪 💪

  • @BornToRun.
    @BornToRun. Рік тому +2

    Fascinating! Great explanation.

  • @mikesymth7243
    @mikesymth7243 Рік тому +1

    Good Video with current real references...thank you

  • @applerunner1184
    @applerunner1184 Рік тому +26

    Great video and thanks! While we are on the subject of controversial topics, a video on Statins would be very useful!

    • @jaynehayes2176
      @jaynehayes2176 Рік тому +2

      Yes agree Statins would be a great topic 👍

  • @jamessaltlife
    @jamessaltlife Рік тому +5

    I'm so confused about nutrition. Why are so many 'carnivore' doctors saying seed oils are bad, saturated fat is good etc? It seems contrary to the scientific consensus but also sounds appealing.

    • @climate-moneymakingcampaig305
      @climate-moneymakingcampaig305 Рік тому

      Theres high probability that they have higher SOCIAL IQ !
      The pattern i notice in these carnivore doctors (which i find the diet wrong myself) is their acknowledgement of SOCIAL RULES CAN MAKE SCIENCE that is not true..
      They are not only studying the studies but they are studying the background of the scientists that produce them, the sponsors and the relations.
      Today the fraud has been so spread that we have titles like :today weve reached a point that any new study should be considered fraud until proven correct" from most famous magazines
      Or "we need to completely ignore the studies that are sponsored by any industry" and etc
      History is trying to teach us :"ANY FIELD OF HUMAN JOBS THAT HAS THE MOST TRUST OF PPL , IS THE MOST PROBABLE TO GET CORRUPTED FIRST AND FASTER"
      Yesterday jesuits (religion) and politicians, today science is the next big one.
      ppl like this dude in the video looks like ignorants who completely ignore such a huge factor.
      I cant believe they read these studies like bibel.
      Pls read about ancel keys, the whole chol. Demonization started from him and his ill intentions. He cherry picked data to make it look dangerous. The money the chol. Demonizers have recieved has been constantly reported to be from sugar industry, u always have chol. But when u eat too much sugar , chol. Gets released in ur blood bcuz sugar destroy veins and chol. Release is ur body reaction to repaire the damages.
      If u are confused about that contrast of CLAIMS, i can almost assure you, the side that believe chol. Is bad are the ones who believe "everything is good, theres no ill intention, why would i doubt a study and etc"

  • @user-wo3mp5le2x
    @user-wo3mp5le2x 3 місяці тому +4

    With the Framingham study, it’s been shown that for all the people that had events, half had “normal” cholesterol. So, there is more to it than that.

    • @meltedsnowman9637
      @meltedsnowman9637 Місяць тому

      We have the statistical power across many many many different studies to show that LDL is causative of cardiovascular disease.

  • @dautoviq
    @dautoviq Рік тому +7

    You're awesome. So much knowledge. Thanks for educating everyone. Loved your podcast with Huberman.

  • @tomasmon5814
    @tomasmon5814 Рік тому

    great one!!

  • @sxhrgvs
    @sxhrgvs Рік тому

    Thanks Layne

  • @thomashugus5686
    @thomashugus5686 7 місяців тому +1

    Excellent presentation and on point science of LDL! Please don’t listen to others pushing pseudoscience with cholesterol/ LDL research

  • @willbrink
    @willbrink 4 місяці тому +3

    Cholesterol denial is a thing, and it's perpetuated by idiots, some of whom should know better. No, cholesterol alone is not the sole cause, but it's the primary driver and there's mountains of data at this point to show it. Layne is spot on here.

  • @kruzbabe3
    @kruzbabe3 4 місяці тому

    Appreciate the financial metaphor. My husband and I try to combine health and wealth education for our clients!

  • @BMGipe45
    @BMGipe45 Рік тому +1

    Where do I sign up to purchase this bridge? Could be a great business opportunity for myself. Thanks in advance!

  • @attilamesaric1088
    @attilamesaric1088 Рік тому +11

    Algosterol!

  • @jfinca
    @jfinca Рік тому

    Spot on!!

  • @byNetak
    @byNetak Рік тому

    NICE ,big up from France

  • @dicktram5305
    @dicktram5305 Рік тому +98

    lane is 100 percent correct on this. I had a heart attack at 47 years old. High hdl.. 65 low triglycerides, in the 50s.. genetically high ldl well over 200. I was told it was impossible to eat it that high, other than that my blood work was perfect. unfortunately.. i was stupid and never got my cholesteral checked because I was thin, exercised all the time so I thought i was good. If i could give one piece of advice to anyone, know your ldl at a very young age. if it is high, address it because I am living proof it does matter. i understand there are alot of other factors that go into this, but high ldl is absolutely one of them

    • @ssj_gabe
      @ssj_gabe Рік тому +10

      While important, the numbers by themselves are just a piece of the puzzle. Those numbers with very low particle count and large particle size would give a completely different outcome than high particle count and lots of small particle size

    • @rualablhor
      @rualablhor Рік тому +6

      Sorry about the heart issue, firstly. But being thin and over exercising isn't necessarily healthy, quite the opposite plausibly. When you say well over 200 ldl... Do you mean more like 215, 250 or like 275, to be more helpful. And you didn't have a second worrying metric at all? What was your BP like at the time, if you don't mind me asking?

    • @AznDudeIsOn
      @AznDudeIsOn Рік тому +7

      So what lifestyle changes did you make to improve your health after this heart attack?

    • @cartermayfield
      @cartermayfield Рік тому

      Out of curiosity, have you had your Lp(a) checked?

    • @rualablhor
      @rualablhor Рік тому +2

      @@cartermayfield doubt it, most don't even know about apoB...

  • @dr.noahweintraub3476
    @dr.noahweintraub3476 7 місяців тому +8

    Love that you’re out there, debunking these scammers and teaching the public to use the scientific method in digesting all the crap out there! Way to go Layne!

    • @jimo559
      @jimo559 6 місяців тому +2

      Yay!
      Go Food Pyramid!
      I love good news about my Fruit Loops for breakfast.
      Dr Layne Norton…..for people like us you!re a god-send.
      “Show me the evidence” that Fruit Loops are bad for you….thats now my canned response.

    • @TheStruggler101
      @TheStruggler101 4 місяці тому +2

      ​@@jimo559
      No nutrition and dietetics organision is going to recommend you eat fruit loops, the strength of the evidence in the literature is extremely strong for the increased risk of chronic disease when refined ultra-processed foods displace whole foods in the diet. People only say this for sensationalism and to support their conspiracy theories. If you look at the recommendations, they support the consumption of whole grains (Whole wheat, oats, buckwheat, brown rice etc) minimally refined bread, legumes (lentils, split peas chickpeas etc.) Of course if your diet is mainly composed of whole foods, such as fruits, veg, wholegrains, legumes, nuts and seeds etc.. then you could eat processed foods occassionally and it would have no significant impact on health outcomes.

  • @martykretz8502
    @martykretz8502 Рік тому +6

    Why dont statins make much a difference on death then?

    • @wread1982
      @wread1982 Місяць тому

      They do if you look at the studies, they keep you from clogging up and needing stints

  • @natewilson5679
    @natewilson5679 Рік тому

    Thank you for sharing this Layne!!!

  • @pablov1323
    @pablov1323 Рік тому +23

    Great video Layne, could you do an educational video about dietary cholesterol? specially egg consumption impact? there are not many out there and I consider you a truthful source

    • @ivanfoofoo
      @ivanfoofoo Рік тому +6

      It's highly individual, for most people dietary cholesterol minimally impacts serum cholesterol.

    • @CharlieFader
      @CharlieFader Рік тому +2

      It really depends on what your baseline dietary cholesterol intake is. If you already get plenty, eggs won’t impact your levels much.

    • @Parker_Miller_M.S.
      @Parker_Miller_M.S. Рік тому +7

      A 2018 meta-regression by Vincent et al reported dietary cholesterol to directly influence serum LDL cholesterol with every 100mg increase in dietary cholesterol equating to about a 4.5mg/dL increase in LDL cholesterol. So it's likely not a bad idea to limit dietary cholesterol especially if one happens to be a hyper-absorber of cholesterol.

    • @snake1625b
      @snake1625b Рік тому +1

      @@Parker_Miller_M.S. do you know around what percent of people don't have their blood cholesterol go up in response to dietary cholesterol?

    • @lenguyenngoc479
      @lenguyenngoc479 Рік тому +3

      @@snake1625b Familial hypobetalipoproteinaemia
      Familial hypobetalipoproteinemia (FHBL) is a condition characterized by lifelong low levels of cholesterol and triglyceride fats in the blood (low concentrations of chylomicrons, VLDL and LDL) and is thought to affect between 1 in 1,000 to 3,000 of the population.
      I probably don't have such genes, I'll stick to what works for now.

  • @penn7853
    @penn7853 Рік тому +3

    Would love to hear your take on the recent study in *nicotinamide riboside* (B3 source in supplements/vitamins), stating not only does it cause breast cancer but facilitates it moving to the brain. Lead author is Elena Goun (University of Missouri?)

  • @patrickcrombmusic
    @patrickcrombmusic 5 місяців тому

    great vid

  • @nalcon1
    @nalcon1 Рік тому +3

    A combination of low HDL and high LOL is the problem. My HDL and LDL are both high. Doctor's scoped my arteries and said my arteries are as clean as a 15 year old. I'm 68! Stick that in your pipe.

  • @onlinemoneyjourney842
    @onlinemoneyjourney842 11 місяців тому

    Thanks ! ❤❤❤ ..

  • @chriscopat7350
    @chriscopat7350 Рік тому

    Good information Layne keep up the good work

  • @weRgaming
    @weRgaming 6 місяців тому +2

    Hey just wondering which metabolic tracer studies you are talking about when you said that only 2% of carbohydrate ends up as body fat (@ 9:48). I'm trying to figure out how that can be true if people gain the same amount of weight regardless of whether they are overfed fat or carbs, calories equal. Any help with this?

    • @greywarden9977
      @greywarden9977 2 місяці тому +2

      I'm not sure if you still care, but here is my understanding:
      If you are in a cal surplus, you store energy as fat.
      It really doesn't matter at where the surplus is coming from.
      From my understanding, the 2% kcal saved as body fat (from carbs) refers to the fact that the body stores dietary fat first and foremost. Simply because it is easier.
      So a very simplified example for a high carb diet. With a 2000kcal maintenance.
      You eat 2500kcal:
      500 kcal protein
      500 kcal fat
      1500 kcal carbohydrates
      Your body is gonna burn mostly carbs for energy because that is easier/faster. It will burn some fat, some protein (much less so, since it is needy for repair functions etc.)
      And since fat is basically ready for storage, the surplus that you store will come mostly from dietary fat.
      So in the end very little of the carbs you consumed will actually be stored as body fat.
      Of course, if you eat 2500kcal only from carbs, the body fat stored from carbs will be literally a 100%.
      So you can't hack your fat storage by only eating carbs or something like that 😂

  • @cocomolium
    @cocomolium 10 місяців тому

    I’ve been trying to figure out why the food industry is moving away from seed oils, is ldl why?

  • @Ocxlocxl
    @Ocxlocxl 7 місяців тому +1

    Great stuff, but as others have said a statin video would be great as there is a lot of conflicting thoughts out there but I trust your process, thanks for your great vids.

  • @SpearedPage
    @SpearedPage Рік тому +10

    Given what you've said here about reducing lifelong exposure to LDL, would it be advisable to reduce eggs? All else being equal (no fried foods, etc.) would you be improving your health if you substituted eggs with lower fat whole foods?

    • @ad3781
      @ad3781 Рік тому +1

      yes

    • @nunobettencourt1429
      @nunobettencourt1429 Рік тому +1

      Eat 1 whole egg per day, rest just eat the egg whites...Reduce/stop butter, try using olive oil and grill meat at low temperatures with it, eat more cooked food and less fried food, don't eat processed food, don't eat processed sweets and pastery, go for whole bread instead of white bread, try to eat more fatty fishes and supplement with Omega acids...Also make sure you get all the vitamin b complexes on point. Most of the vitamin B's help your body reduce LDL cholestrol.
      Trust me, I know. I'm 34 year old and had a disturbing reveal last check up, 230 total cholestrol, 190 ldl, 65 hdl, with 14% body fat...It was a eye opener specially on not taking nutrition advice from fitness industry without science backing it. No longer while I dirty bulk and I rather much prefer progressing slower in the gym without risking CVD.

    • @climate-moneymakingcampaig305
      @climate-moneymakingcampaig305 Рік тому +2

      Ive eaten eggs every single day for decades bcuz it was the cheapest and we were poor. Nothing happened to my old parents and not for us..
      Use ur common sense , we would have been extinct thousands of yrs ago already if sat fat or eggs were dangerous for us

    • @donewittit6607
      @donewittit6607 10 місяців тому +7

      @@climate-moneymakingcampaig305 anecdote doesn't equal science

    • @nichtsistkostenlos6565
      @nichtsistkostenlos6565 9 місяців тому +4

      It really depends on your specific situation. If you're not prone to genetically high LDL, whole eggs are probably going to be fine in reasonable quantities and in an otherwise balanced diet. Increased dietary cholesterol is not a direct causal increase to blood serum cholesterol either. Generally for some kind of dietary intervention like this, it really needs to be tested at the individual level. You could get a baseline for your LDL-C (or even better ApoB) and then add a few whole eggs into your diet and then test again after a month or two. If it didn't make any drastic changes to your blood-work, then great, if it does, then that gives you some indicator as to how well you tolerate saturated fat and dietary cholesterol and you can adjust your diet accordingly.

  • @shaun4443
    @shaun4443 7 місяців тому

    What is yours HDL and LDL Layne?

  • @chrisleonard8435
    @chrisleonard8435 Рік тому

    How much for the bridge. Could I put a toll on it.

  • @GVS
    @GVS Рік тому

    10:18 in general, if you hear someone "whoop" in the crowd during a nutritional presentation, the person is probably full of it 😂😂😂

    • @hektik27
      @hektik27 Рік тому

      happy to see big geoff around here

    • @Parker_Miller_M.S.
      @Parker_Miller_M.S. Рік тому

      Too many 🦆🦆🦆(quacks) in nutrition and health space. It's infuriating honestly.

  • @derekconn9950
    @derekconn9950 2 місяці тому

    Lpa is what truly gets “stuck” in the walls, but it still doesn’t get stuck for no reason. Damage to the wall due to many risk factors caused damage and the body tried to repair it, LPa prevents fibrinogen from removing it however, which is a good and bad thing. But it’s not directly the LPa apob or ldl that is bad per se, it’s a process and the process is sometimes not fast enough or happens to often in the same place, causing the problem

  • @auslanderbuchsbaum5623
    @auslanderbuchsbaum5623 Рік тому

    Subscribed. Your channel is really cool. It made me question certain things that I took for granted about nutrition.

  • @jamie5mauser
    @jamie5mauser Рік тому +2

    How about calcification of arteries? Does that make calcium bad? I’ve also heard the argument that we don’t have atherosclerosis in our veins, although our Venous system has the same levels of cholesterol. Would love to hear to discuss

    • @wierdgeniuses
      @wierdgeniuses 9 місяців тому +1

      Hi, I know I am late, but just felt like answering to the best I can. Calcification of arteries isn't really related to dietary calcium. Rather, it's a marker of plaque formation and inflammation. The physiology is pretty complicated (and honestly not 100% understood), but after the wall of the artery is damaged by a combination of cholesterol deposition/retention, shear stress from turbulent flow, systemic inflammation, etc, and that leads some cells to a local inflammatory cascade that leads to plaque formation and calcium deposition (kind of think like the "scar").
      The reason we don't see as much atherosclerosis in our veins is because veins just have lower flows to deal with (so less shear stress on the wall of the vessel) and don't have the same cell structures that make plaque (the inflammatory cascade starts in the smooth muscle layers of the vessels which are far more prominent in arteries). Clots in veins are mostly reflections of either states where the body is very prone to clots (like cancer patients or those with genetic disorders such as Factor V Leiden) or if blood flow is really slow in an area (prolonged immobilization is a huge risk factors for deep venous thrombosis).

  • @isaiahreno
    @isaiahreno 11 місяців тому

    PLEEAAASSE do a video on "How bad is saturated fat?"

  • @OisteinThomassenMScPharm
    @OisteinThomassenMScPharm Місяць тому

    Thanks for creating this video, Layne. Why are so many people profoundly obsessed with trying to debunk facts? High levels of LDL-C and ApoB increase the risk of developing atherosclerotic plaques and, consequently, increase the risk of a heart attack. A heart attack! Not exactly something you'd wish for. Many people, including some high-profile UA-camrs (even MDs), are simply sharing their own hypotheses, thoughts, and speculations to downplay the importance of LDL-C and ApoB in this context. Such discussions are indeed intriguing, however, you cannot debunk a fact by merely suggesting alternative "I think" theories. Yes, obviously, there are published articles that question the LDL hypothesis, however, these are not evidence to reject it. That's not how science works.

  • @northeastern07
    @northeastern07 Рік тому

    What’s a good number for LDL and what’s yours?

  • @lutherlessor4029
    @lutherlessor4029 Рік тому

    Good mental estimate for the percentage difference example. 1.08^50/1.07^50 is about 1.6

  • @ThingsYoudontwanttohear
    @ThingsYoudontwanttohear Рік тому +5

    Before I am late:
    Congrats to Layne for becoming a billionaire by selling the Skyway Bridge!
    I knew someone would buy it one day.🤠

  • @bbbshot
    @bbbshot Рік тому

    Can address the research/concerns of egg consumption and association with cancer (ie colon and prostate)?
    Supposedly it has to do with choline. Although the study that's cited used choline supplementation vs dietary choline (eggs).

  • @thelastMaster100
    @thelastMaster100 8 місяців тому

    My triglycerides are always high. But they were they highest after I had two mcdoubles right before I got them tested. (It was like 800)

  • @blainebowling3303
    @blainebowling3303 Рік тому +14

    Excellent job on helping to simplify a very complicated and nuanced subject that is cholesterol!!
    I once thought like quite a few docs that it was ratios and partial size that mattered. Now I’m on Ezetimibe and Rosuvastatin and my LDL and APO-b at my childhood levels… Luckily my LP-a is genetically low.

    • @JWB671
      @JWB671 Рік тому

      How lean are you? ie. what is your waist size and height?

    • @blainebowling3303
      @blainebowling3303 Рік тому +1

      *particle size

    • @theonline9
      @theonline9 Рік тому +2

      In some fashion, the idea that we cant live healthy or long without a stack of drugs, just doesn't feel right. Maybe it's wishful thinking but shouldn't we be able to accomplish this with lifestyle? 3x widowmaker survivor

    • @blainebowling3303
      @blainebowling3303 Рік тому +3

      @@theonline9 I understand what you’re saying and I fought it for a very long time. I exercise every day of the year in some form or fashion. I own a sustainable chicken farm which “requires” some form of strenuous physical activity every single day of the year. I keep a regular sleep schedule and prepare most of my own food. I have access to pasture raised meat and eggs which either I raise myself or farmers I co-op with produce. The beef I consume is belted galloway which has the same fatty acid profile as wild caught salmon and when ground is only 2% fat and very low saturated fat. I have a training coach. I ruck a mile every day when I walk my dogs.
      With all that my cholesterol is always over 200 and my LDL is always over 150 and if I eat any substantial amount of liver my total Cholesterol climbs over 350 and my LDL over 250. Since I don’t consume any type of high glycemic carbs on a regular basis then my triglycerides are never over 150 and normally well under 100.
      With the meds my total cholesterol is under 120 and my LDL is about 40.
      At this point I just look at it as another form of technology. You say it’s not natural but you weren’t born wearing clothes. Clothes are a form of technology. Just like the house you live in and the hand held computer we’re communicating on…
      I’m just trying to live the healthiest life I can. But hey… you do you!

    • @theonline9
      @theonline9 Рік тому +1

      @@blainebowling3303 hey man, no offense or judgement intended. I was just looking at it like these drugs aren't without side effects. Multiple drugs equals multiple potential side effects, often year's out. My dad was on a high dose of statins for year's and needed bilateral knee and shoulder replacements. He's since become a vegetarian on a low fat, high carbohydrate diet and come off his meds. I feel like shit on that kind of diet and much better on meats and fruits.
      As a father is like to live a long life and ensure my kids have a father. It's a journey and I'm trying to understand the difference in how people interpret the data.

  • @lukeclaydon6670
    @lukeclaydon6670 Рік тому

    Great 👍

  • @onyabikejoe7643
    @onyabikejoe7643 Рік тому +2

    Dr. Layne Norton. What should I do regarding my high LDL cholesterol reading? Diet and exercise is making no difference. My doctor prescribed medication called Crestor, but I’ve heard so much negativity about Statins. Should I take the Statins?

    • @karlhungus5554
      @karlhungus5554 Рік тому +1

      If Layne even sees your comment, I'd guess there's a 99.9% chance he won't be able to answer your question. Not because he doesn't have knowledge and experience, but because he can't give medical advice. But, hopefully I'll be proven wrong and Layne will offer some pointers.
      In the interim, what are your details? Age, current diet and length of time, previous diet and length of time, do you work second or third shift? Or, overnight? Any diagnosed health conditions, aside from high LDL? Do you sleep well? How many hours do you sleep per night? Etc., etc.
      There are a lot of smart people (not me) that watch these videos -- including healthcare workers -- so maybe leaving some additional information might help someone to offer some ideas. Good luck.
      p.s. That's a great looking Yamaha XJR1300 in your profile photo.

    • @gregegan79
      @gregegan79 Рік тому +1

      Each to their own. I would give CPR to someone that needed it despite the risk of breaking their ribs. I am on statins based on the same logic.

    • @Jordy-927
      @Jordy-927 Рік тому

      The negatives of NOT taking the statins could be a jammer or even death. I’d say those outweigh the negatives you’ve heard about taking them.

    • @rualablhor
      @rualablhor Рік тому

      Unless it's genetics, I find it difficult to find diet and exercise did nothing. Perhaps you mean it didn't make enough of a difference🤔. Perhaps you didn't change your diet /exercise regiment much...say, what/how exactly did you exercise, and for how long, if you don't mind me asking?

    • @onyabikejoe7643
      @onyabikejoe7643 Рік тому +4

      @@Jordy-927 Apparently statins reduce the mortality rate from CVD by 28%.

  • @jj4829
    @jj4829 Рік тому +2

    Can you talk more about fat in the blood?

  • @ricomartin8278
    @ricomartin8278 Рік тому +4

    There's never been a more confusing time to eat

    • @mementomori29231
      @mementomori29231 Рік тому +2

      Not really. Watch nutrition made simple. Dr. Gil shows the body of scientific evidence vs individual studies. Dr. Gil has made the topic pretty understandable from a macro and micro view.

    • @mementomori29231
      @mementomori29231 Рік тому

      @@ExtraSubtle Bart Kay is a total fool then.

  • @coach_chonko
    @coach_chonko Рік тому +6

    Hey Layne, I have a genuine question, hope you can answer. The ingestion of high LDL cholesterol foods causes an increase of plasma concentration, but this increase in concentration is an acute response. You have consumed a whole lot of literature on this subject, do you remember reading if this acute response is cause of the increase in CVD risk or is the CVD risk mainly caused by chronic LDL cholesterol levels which may be less related to dietetic choices?

    • @Parker_Miller_M.S.
      @Parker_Miller_M.S. Рік тому +5

      Hope I can help! Foods contain either free or esterified cholesterol which can impact serum cholesterol (as well as multitude of fatty acids). A meta-regression study by Vincent et al 2018 demonstrated a non-linear increase in blood cholesterol for every 100mg of cholesterol eaten which increased blood cholesterol by about 4.5mg/dL. People who are hyper absorbers of cholesterol have mutations in proteins within their small intestine called ABCG5 & ABCG8 which reside next to the primary cholesterol absorption protein NPC1L1. These hyper-absorbers thus reabsorb more cholesterol from the bile acids/salts used in digestion and absorb more from dietary source and have higher blood cholesterol levels. Conversely those who are hypo-absorbers tend to have lower blood cholesterol. In the presence of a diet high in cholesterol such as eating whole eggs, shrimp, etc., This can increase serum LDL cholesterol. So eating cholesterol consistently can lead to prolonged increases even if the response were acute. Hope that helps

    • @ladagspa2008
      @ladagspa2008 7 місяців тому

      Dietary cholesterol only raises blood cholesterol level of 1% people who are hyperabsorbers. The problem is saturated fats and trans fats, those raise LDL. LDL will be raised as long your diet has loads of sat fats, when you change diet for good then LDL will also come down. LDL reacts quickly to diet change.

  • @patriotfury4013
    @patriotfury4013 Рік тому +5

    The only thing that corrected my cholesterol issues was lowering my calorie intake, balancing my healthy fats and exercising regularly

  • @C0d0ps
    @C0d0ps Рік тому

    To whoever reads this,
    I hope you have a wonderful day and no matter what stay happy as that is what matters most in life,
    You are truly amazing and no one can ever take that away from you,
    Be happy and enjoy life,
    We don't have long on earth so make the most of it,

  • @tgow7304
    @tgow7304 Рік тому

    hey layne
    how do we lower our ldl cholesterol levels?

    • @samvandervelden8243
      @samvandervelden8243 Рік тому +4

      Replace saturated fat with unsaturated fat, eat a lot of fiber and be at a healthy bodyweight

    • @lenguyenngoc479
      @lenguyenngoc479 Рік тому +1

      google it when, 90% of them it's correct except u purposely ignore them. Or being a little nerdy like me choosing to read directly from the sources and not from journals or websites.
      Anyone say anything without a study backing it up is a quack, saying without a link or study name is also a quack since u can't fact check and see the sponsors of studies.
      Most of the time carnivore won't cite studies, I wonder why🙂
      There's a time I saw Saladino cited and he's completely mispresented author's works and people on his channel didn't seem to check it.
      How gullible they are🚶‍♂️

  • @RW-ql2wy
    @RW-ql2wy 7 місяців тому +1

    I’m pretty sure he mentions a bigger picture than “cholesterol is misrepresented”. You are like the media only playing certain clips and not the full picture.

  • @uberneanderthal
    @uberneanderthal Рік тому +7

    1:36 - 1:40 this should've been the entire video. the rest is just noise, lies, and obfuscation.
    6:00 "it's essentially a randomized control trial" yeah, just like I'm essentially a billionaire. in Colombian Pesos. here's a clue layne: an actual RCT wouldn't have an error bar that takes up half the graph and completely nullifies your "linear effect". whoops.

  • @karlhungus5554
    @karlhungus5554 Рік тому

    Here's Layne's (nearly four hour) appearance on Andrew Huberman's podcast:
    *Dr Layne Norton: The Science of Eating for Health, Fat Loss & Lean Muscle | Huberman Lab Podcast #97*
    ua-cam.com/video/K4Ze-Sp6aUE/v-deo.html

  • @bobdec6665
    @bobdec6665 8 місяців тому

    Hdl ratio with Triglycerides is the most impirtant

  • @joselopes3825
    @joselopes3825 Рік тому

    How much 4 D skies cheaper 🤔, 20 will be enough right?

  • @derekconn9950
    @derekconn9950 2 місяці тому

    And hdl carries more “cholesterol” than LDL. And they never truly say a mechanism in how it penetrates the blood vessel wall

  • @Macatho
    @Macatho 7 місяців тому

    You nailed it there in the end.
    They really want to say "eat your butter eat your bacon", because olive oil or rapeseed oil just isnt as tasty.

  • @mikalali4958
    @mikalali4958 11 місяців тому

    I lost the context of the video you made - I don't know what Gary was going to say next

  • @april9337
    @april9337 5 місяців тому +1

    "Poor cholesterol, why doesn't anyone like me?"

  • @rualablhor
    @rualablhor Рік тому

    Is an independent risk factor akin to driving and automobile accidents...if you don't drive, chances are you are not getting into an auto accident. Unless, you get hit by a car when walking, cycling or, say, skateboarding, correct? If high LDL is indeed an independent risk factor...then that means you can't look at a second metric in your cbc or lipid panel to be concerning, correct? Lastly, you would have to go test apoB, correct, despite your triglycerides is under 100, your hdl is, say, 70 and a1c is 5.3 and BP is 115/70? Imo the danger of LDL is rather puzzling, no? Keep it under 130 and forget about it?

  • @DrAJ_LatinAmerica
    @DrAJ_LatinAmerica Рік тому +2

    as with ALL things, big picture matters. context matters, anything reviewed in a vacuum will lead the viewer down the wrong path.

  • @mrtriangle1825
    @mrtriangle1825 Рік тому +1

    Why do they hate insulin so much 😔

  • @tcjmods73
    @tcjmods73 Рік тому +3

    Here I am, with heart disease at 34yrs, and the experts all have different/opposing opinions about the cause and how to treat. I’m screwed

    • @carnivoroussarah
      @carnivoroussarah Рік тому +2

      No please listen to me. Its saturated fat and also consume more omega 6s, eat less overall fat, workout, cut out dairy and eggs altogether. Lean non red meat only.

    • @carnivoroussarah
      @carnivoroussarah Рік тому +1

      I went from 248 to 187 in a year. 112 to 84 in a year too for LDL.

    • @MichelleReacts94
      @MichelleReacts94 Рік тому

      Eat foods like eggs white and lean (5% or less) meat skim milk low fat yogurt

    • @RagdyAndy
      @RagdyAndy Рік тому +1

      @@carnivoroussarah WTF BS advice

    • @rualablhor
      @rualablhor Рік тому +1

      There are various reasons...go check your apoB and LP(a), the tests shouldn't be expensive. Regarding ldl levels...I work my tails off (mostly exercises driven, some diet modifications) and only lowered my ldl by like 15 pts in 4 months...

  • @theonline9
    @theonline9 Рік тому

    Do you give credence to the writing of doctors like Dr. Malcolm Kendrick?
    Also, is there a trade-off where lowering cholesterol raises mortality or impacts health negatively in some other way?

    • @Parker_Miller_M.S.
      @Parker_Miller_M.S. Рік тому +1

      Nope! Unless LDL is completely eliminated, super low levels below 50mg/dL appears to have zero negative impact on health or longevity.

    • @theonline9
      @theonline9 Рік тому

      , there seem to be quite a few doctors talking about this over the last 30 years. Like anything where people stake a claim on either side of an argument is like to understand his they got there.

    • @thedoc5848
      @thedoc5848 Рік тому

      ​@@Parker_Miller_M.S.based on what long term RCTs?

  • @gerardmillar1680
    @gerardmillar1680 Рік тому +6

    First time you i've seen you do one on cholesterol. Thank you - I hope to see more, this was actually really, really good. I've found for me a ketogenic diet is a great way to loose weight and in your books you say that a sustained caloric defecit is the most important thing. When I did keto to loose around 30kg I had my blood lipids done all the time. My LDL went up and down, up and down like a yoyo as the weight fell off. The doctor was "you need statins", "your cholesterol profile is great", "you need statins".... No idea if my change in diet was the casual reason for the fluctuating cholesterol as I had nothing to compare it to before doing keto. I guess my question is, is the elephant in the room still weight loss? If you find a diet that has worked for you and can sustain a caloric deficit over the long term does this mitigate almost most health risk?

    • @stargazerbird
      @stargazerbird Рік тому +5

      Same for me. I was losing great on keto and then had a blood test. Sky high and dr concerned. It was actually low on a previous test when I was already slim. I stopped the diet but the weight loss also stopped. Kept trying to diet off my fat with high carb low fat but it was a slow journey never getting to the destination.
      I am back on high protein/keto again now. It is so satiating I find it way easier to stick to my calorie deficit. I am just accepting that my LDL will be high while I lose weight. They say cholesterol peaks with any fast weight loss so I think that is what happened to me. I sometimes wonder what would have happened if hadn’t had that blood test four years ago. Would my weight have got to goal then? Surely that is healthier?
      I didn’t do the statins. I went plant based instead. But I had low grade IBS the whole time. Finally gave up on fibre/volume eating after a month of constant pain and bloating. I find it interesting that there is a large minority of people like me for whom the science based diet doesn’t work. Look at the carnivore forums and you will see stories of autoimmune disease like joint pains and skin conditions being cured on zero fibre.
      There is more to health than LDL. I am 70. Never been substantially overweight. Mostly low BMI, always active. I think my risk is acceptable at this point in my life to be lean and free of discomfort.

    • @alekexodus5984
      @alekexodus5984 Рік тому +2

      Gerard, from what I've learned from doctors I trust about this specific issue--checking cholesterol while losing weight--suggests that you should expect to see variations in cholesterol while losing bodyfat. The fat you're losing doesn't just "go away". It has to be processed by your body, which can increase your serum levels temporarily.
      Those doctors recommend not checking your cholesterol levels during a weightloss phase; check them two weeks after you enter maintenance because you're likely to see a "truer" measure at that time.

    • @ladagspa2008
      @ladagspa2008 7 місяців тому

      Two things
      1. High saturated fat diets increase LDL, so definitely not suited to be long term diets.
      2. Weight loss can also spike cholesterol during the extended calorie deficit. So only check lipid levels after one month of maintenance on your desired diet.
      All in all, keto is good for weight loss and maybe some other issues, but it is a bad choice for long term diet. It clogs arteries.

    • @henrypimentel4389
      @henrypimentel4389 5 місяців тому

      2:44 ​@@stargazerbird

  • @tmoney7643
    @tmoney7643 Місяць тому

    All I know is... my LDL was lower when I ate fast food... my LDL went up on the KETO diet! I went back to a high carb and fast food diet to lower my LDL!! AMEN.

  • @Stopsign002
    @Stopsign002 Рік тому

    For algor the rhythm!!

  • @nightbite6882
    @nightbite6882 Рік тому +1

    What is the measure of cardiovascular risk? A count of cardiac events? Useless! The data needed here is a lipid panel alongside a cac score.

  • @JohnSmith-zs1bf
    @JohnSmith-zs1bf Рік тому

    Isn't it true that high LDL is associated with longer lifespan?

    • @climate-moneymakingcampaig305
      @climate-moneymakingcampaig305 Рік тому

      Yes its true but for clowns that treat studies like bibel like this dude its a completely different universe and i advice you to ask the question from a person that has a good memory like this dude but also has high social IQ and understand the "RELATIONSHIPS" can make new "science" , like those 3 harvard "scientists" have produced a study that said chol. Is bad but theyve recieved money from sugar industry which happen to be the exact reason chol. Increase in blood flow in the first place!
      U have chol. But they will become problem only when u eat sugar too much.
      I remember ive eaten eggs every single day, for decades (bcuz it was the cheapest and we were poor" , notme not my old parents have experienced nothing.
      I remember the big piles of animal fat that my mother used to turn into oil, every other month , nothing nothing happened to themselves and not to us..

    • @climate-moneymakingcampaig305
      @climate-moneymakingcampaig305 Рік тому

      pls use common sense, dont think with TRUST TO CERTAIN PPL, some big names with phd are SOCIALLY COMPLETELY BRAINDEAD !
      They completely ignore the biggest factor "THE HUMAN RELATIONS" that shape the science and debunk 100 thousands of yrs of sustainability of a healthy practice

  • @awnurmarc
    @awnurmarc Рік тому +4

    Thank you for this Lane. Have there been any studies showing that LDL-lowering interventions have a positive effect on all-cause mortality?

    • @snake1625b
      @snake1625b Рік тому +7

      Yes cholesterol lowering drugs like statins have a strong effect on lowering heart disease. Gil Carvalho has a great video on this

    • @SuperEddie0228
      @SuperEddie0228 Рік тому

      @@snake1625b Are you seriously recommending statins?

    • @snake1625b
      @snake1625b Рік тому +1

      @@SuperEddie0228 Yes I am recommending statins (for those who have high cholesterol and dont have the will to immediately change their lifestyle). The vast majority of researchers in the field commonly agree through the totality of the evidence that statins lower risk for heart disease and that any cons of the drug are worth the risk.
      If you think otherwise then its probably because you've fallen for quacks online like chiropractors and naturopaths. or other quack MDs like Dr. Fung.

    • @thedoc5848
      @thedoc5848 Рік тому

      ​@@snake1625bnot since the 2004 publication laws were introduced.
      Since then statins have no effect on mortality and very little effect on CVD incidence

    • @snake1625b
      @snake1625b Рік тому

      @@thedoc5848 This is not what the majority of heart/health organizations and universities sad. They all recommend statins to reduce risk for heart disease, that recommendation did not change after 2004.

  • @Combinationlock
    @Combinationlock Рік тому +5

    In relation to all cause mortality people with lower cholesterol die younger and higher cholesterol live longer.

  • @joey-bladez
    @joey-bladez Рік тому

    Lane could you please drop some knowledge on Thomas Dale hours recent interview with”Dr.” Anthony Chaffee. This is asinine bro. Thx, You’re the best bro

  • @JoeKool33
    @JoeKool33 Рік тому +9

    I had a cardiologist put me on a cholesterol med a couple years ago because he said even though my HDL and LDL were in the normal range, it was the ratio that was not great and I should lower my LDL to get a better ratio. Even though the independent risk factor is the LDL and not related to the ratio so maybe my doctor didn't need to lower my LDL, for the sake of the ratio anyway, but I guess it still works out since now my LDL is lower than it was. Wish I knew this when I was 25 and not learning it at 50 though. Better late than never. Thanks Layne.

    • @bigz5262
      @bigz5262 Рік тому +8

      The doctor didn’t need to lower your cholesterol, they needed to write you a prescription to get paid

  • @whitecreek
    @whitecreek Рік тому

    Way to go in dismantling passionate gurus/speakers. Easy does it!!! So tranquilizing. 😊 👏👏👏👏👏

  • @Magic_beans_
    @Magic_beans_ Рік тому

    If I’m gonna buy a bridge, I want the one from _True Lies_ .

  • @fla8731
    @fla8731 Рік тому

    algo

  • @user-ib3jm9tz5u
    @user-ib3jm9tz5u Рік тому +4

    Evangelizing saturated fat 😂
    My fav fat is the mono unsaturated one, you won’t get into a fight with anyone promoting that. Maybe tied with the omega 3s, those also seem universally loved. Small fatty fish, an avocado and some olives please, sir 🤤

    • @lenguyenngoc479
      @lenguyenngoc479 Рік тому

      Yeah, but when u see what monosaturated fat does to your endothelial cells, it wont look like an angel anymore 👀

  • @mjordan5382
    @mjordan5382 Рік тому +9

    Why do you dismiss Bart Kay? He is a Research Scientist and a Cardiovascular Pathophysiologist. Is it possible that you may not be aware of your own incompetents?

  • @griffinhenderson1
    @griffinhenderson1 Рік тому +1

    The guy you’re attacking could predict death to the month. I think you’re incorrect about exposure over a lifetime regarding the heart.

  • @jj4829
    @jj4829 Рік тому +1

    Layne you should do weekly livestreams, we can donate and ask questions etc

  • @ladybrooks3885
    @ladybrooks3885 Рік тому +5

    My first video of yours. What a gem you are! You explain it so well. Thank you!

  • @AleksandarIvanov69
    @AleksandarIvanov69 Рік тому +8

    Give people like Gary Brecka their credit for pushing the science further and further for clearer explanations to the point where people like Layne emerge and educate the proper, clear science.

    • @Melesniannon
      @Melesniannon Рік тому +4

      Or not. That's a bit like saying "Give arsonists credit so that firefighters can be heroes". Layne talks about when the reserach that Brecka claims isn't done, has been done. It's happened independently of Brecka, because people are constantly trying to better understand how the human body works. They don't need the Breckas of this world, all they do is set us back by convincing people of the wrong things.

    • @AleksandarIvanov69
      @AleksandarIvanov69 Рік тому

      @@Melesniannon yes, that's exactly what I am saying and more, but I disagree with the interpretation.
      Do you think there are arsonists for no reason?
      Anything wrong in the world emerges for a reason. It is a symptom. Then anyone involved deals hopefully in a productive way with the symptom and everyone is better off for it.
      Without people like this Gary guy showing that clearly there is a disconnect between science and people, no one would deal with that disconnect and people will keep suffering.

    • @Melesniannon
      @Melesniannon Рік тому

      @@AleksandarIvanov69 Sorry but the notion that anything wrong in the world emerges for a reason is a baseless assumption and can just be dismissed.
      There are *causes* for arsonists. Not reasons. They don't serve some goal, what would even decide what those goals are?
      People like this Gary CAUSE the disconnect. There isn't some disconnect and than some Gary comes along and spreads the bad word to people who need to refute it. There's a Gary and they spread the word to people who get disconnected because of him.
      Without the Garys of the world, the Laynes of the world would be able to spend their time researching new interesting things rather than having to deal with the same nonsense other and over.

    • @AleksandarIvanov69
      @AleksandarIvanov69 Рік тому

      @@Melesniannon "baseless assumption" did you just say that causation doesn't exist?

    • @Melesniannon
      @Melesniannon Рік тому

      @@AleksandarIvanov69 I just said that assuming causation by assuming causes begs the question.

  • @martinb545
    @martinb545 Рік тому

    Which role does the Apo B value play ? I understood that the number of Apo B usually correlates well with LDL Cholesterol, but not always. Is LDL or Apo B now the direct market for atherogenic risk ? Thanks

    • @Parker_Miller_M.S.
      @Parker_Miller_M.S. Рік тому +6

      The concentration of serum apoB gives a better picture of one's risk because apoB is on LDL cholesterol.

    • @wierdgeniuses
      @wierdgeniuses 9 місяців тому

      To add more context, in a perfect world, we would probably just directly measure ApoB and Lp(a) and use that to stratify risk. Unfortunately, we don't have a ton of data on what exact ApoB levels confer what risk. This is probably because measuring ApoB is more intensive, difficult, and expensive making widespread use not great (many hospital labs don't even have the ability to directly measure it if I am not mistaken.). Also, except for patients with chronically high triglycerides (> 200 mg/dL), LDL-C and non-HDL-C combined correlate pretty well with ApoB levels to the point that we probably just don't get great value from measuring ApoB directly in the general population. However, it is reasonably indicated to measure ApoB (and maybe Lp(a) now that trials are being done to directly treat it) in patients with heart attacks who have low levels of cholesterol (LDL < 70 mg/dL and non-HDL < 100 mg/dL) at baseline. Hope this helps!

  • @wread1982
    @wread1982 Місяць тому

    Crestor dropped my cholesterol by 60%, no side effects either

  • @lloydlockwood9459
    @lloydlockwood9459 Рік тому +1

    How does this translate to dietary cholesterol? Does dietary cholesterol directly correlate with blood cholesterol concentration? I currently eat a lot of eggs and I love them, but might dial it back a bit if it is likely to increase my heart disease risk factors.

    • @betrayedpredator8826
      @betrayedpredator8826 Рік тому +3

      That depends on your genetic response to dietary cholesterol

    • @carnivoroussarah
      @carnivoroussarah Рік тому

      Dial them back don't listen to anyone else I promise it fixed mine

  • @anishveigas2514
    @anishveigas2514 Рік тому

    🙌

  • @hamm0155
    @hamm0155 Рік тому

    That was a good one!

  • @pradyumnacalisa3770
    @pradyumnacalisa3770 Рік тому

    What the algorithm

  • @BeatsAndMeats
    @BeatsAndMeats Рік тому +10

    Sweet! Let’s all take 840mg of Repatha (PCSK9 inhibitor) every month for like 4 decades, reduce our LDL to 0mg/dl and then we can still ask ourselves why 48% of all CVAs happen in people with normal or low LDL-C (as of 2008). It seems like we’re missing something here.

    • @donewittit6607
      @donewittit6607 10 місяців тому

      Keep it real you eat a lot of saturated fat be honest😂😂😂

    • @wierdgeniuses
      @wierdgeniuses 9 місяців тому +5

      You might already know all of this, but to add some nuance for others who read this, CVA is a much more complicated phenomenon than just atherosclerotic disease of large arteries. For example, if someone has atrial fibrillation and an embolic stroke from that, lowering cholesterol only helps marginally (a clot forming in someone's heart because of poor flow and being flung to his brain has little to do with cholesterol). Similarly, if someone has microvascular disease from long term systemic hypertension, smoking, chronic kidney disease, etc, reducing cholesterol also only has limited effects as the atherosclerotic disease may not be the major mechanism to these anyway. Cholesterol lowering has the best effect on types of stroke where we see large vessels occluded by an atherosclerotic plaque (this makes sense because this mechanism is most similar to what we see in heart attacks). Unfortunately, these make up way less than 50% of strokes. Also, there is the entire other entity of hemorrhagic strokes (brain bleeds) where the link between cholesterol and events is pretty questionable at best.
      TLDR: CVAs are a from a very complicated set of different disease processes, and cholesterol may not be well linked with some of the mechanisms of CVA.

    • @marcdaniels9079
      @marcdaniels9079 9 місяців тому +1

      What’s the problem in saving the 52% then !??? 😅

    • @BeatsAndMeats
      @BeatsAndMeats 9 місяців тому

      @@marcdaniels9079 Because thats not how the body works. If people are having CVAs in the absence of high cholesterol, it means that SOMETHING ELSE is causing the CVAs. The answer is blood pressure. Pure and simple. Hypertension in the absence of hypercholesterolemia still causes CVAs, hypercholesterolemia in the absence of hypertension does not cause CVAs, unless its extreme (greater than 300.) They've done the studies already. When you lower LDL-C to effectively zero, the subjects die... all of them. Whoopsiedoodle! The reason why is that cholesterol is a part of the immune system, and you need it to, you know, not die of other things. But cholesterol is really easy to measure, so we still use it. It does play a part, but the elephant in the room is high blood pressure, and when you have high blood pressure, it definitely helps to have lower LDL-C, but it helps MORE to have lower LDL-P.

  • @Chris-ii7ro
    @Chris-ii7ro Рік тому

    For algor

  • @danielformica-yourvocalteacher

    Ok someone help me out I was told because my hs-crp is very low I don’t need to worry much about the ldl. True false what’s up here

  • @Lion19morethanpower
    @Lion19morethanpower Рік тому

    Please fix your audio. Your channel could be so much more popular

  • @luisfer14240
    @luisfer14240 8 місяців тому

    👍🏻

  • @superfinevids
    @superfinevids 9 місяців тому

    Its not the cholesterol, its the heme iron. Heme iron tears your arteries and that inflammation opens holes for cholesterol to slip into those cracks and build up. Your immune system doesnt recognize the cholesterol so it covers it in calcium which increases inflammatory markers which increases more cholesterol to the site. As cholesterol is the bodys patch work for new cells. Over 20 to 30 years of eating this way the arteries to the heart get ao blocked that you get a heart attack or stroke if its near the brain. Dont eat meat people your body isnt made for it. All your ancestors who ate meat had heart disease and they only ate meat because they had to live outside of their natural equatorial habitats.

  • @nichtsistkostenlos6565
    @nichtsistkostenlos6565 9 місяців тому +1

    The only way you can still think the LDL-C and ApoB are not independent risk factors for CVD is pure ignorance. I used to think the same exact way as Gary Brecka and then I saw the just absolute mountains of evidence to the contrary and essentially my opinion changed on the subject overnight by force. You can't actually look at the evidence and even squint to find any inconsistency here in the data.

  • @mooseworld5678
    @mooseworld5678 Рік тому +1

    I wonder what Paul Saladino would have to respond to this.

    • @karlhungus5554
      @karlhungus5554 Рік тому +3

      Paul "__________ is bullshit!" Saladino

    • @Parker_Miller_M.S.
      @Parker_Miller_M.S. Рік тому +6

      Well he's a quack so his opinion is irrelevant

    • @mooseworld5678
      @mooseworld5678 Рік тому

      @@Parker_Miller_M.S. that so true. I always hope he responds though because I enjoy watching him get torn apart LOL