Thank goodness we have medications like SSRIs. My quality of life is better. If i had of been sick 100 years ago, I would have been locked up for life.
@@eclark9965 The pill is supposed to give you some energy so that you can actually address the problems. Like push starting a car with a dead battery so you can take it somewhere where you can fix the problem.
I feel like, especially these days, everybody is struggling with mental health and could benefit from careful/ intentional therapeutic use of substances like these.
I've been on SSRIs for almost 15 years. I wouldn't even recommend these medications to my worst enemy. Very little is known of the extent of the long term effects on the brain. Over the years my symptoms has just gotten worse and it's extremely hard to quit because of the severe side-effects it causes. Dizziness, electric shock sensations in the brain, anxiety, depersonalisation, sweating, balance problems, trouble walking, nightmares etc. The list goes on and on and on. This is a 40 year old medication and now just serves as a massive cash grab for the pharmaceutical companies. Recent studies show that serotonin might not even be linked to depression after all and that SSRIs are pretty much as effective as a placebo for treating mental illness. There will come a time when we look back on SSRIs the same way we look back on the medical use of heroin, cocaine and methamphetamine today.
As a neuroscientist, I find this very informative. You were able to catch a lay audience & as a registered nurse who studied neuroscience in my doctoral program, you did a great job explaining this. Thanks!
Are you still studying and can you help me understand why my Tourette's has come back (after 40 years of not having any tics.) They're calling it rare TD now, after I received a Maxolon for a migraine. I've looked up tardive dyskinesia. And it seems like that could be the case, however, it also feels like Tourette's because I have exactly the same motor tics I had when I was 13 and younger. Toes, shoulder, eyebrows, bubble feeling under my top lip. Also my back and legs Twitch all night.. Ok so the biggest reason that I would like to speak with somebody who might understand this whole serotonin and dopamine thing, is because this is the medication that they give to pregnant women for nausea. It's not recommended in some countries for children under 10 due to the nerve damage side effects. Yet recommended for the foetus.. I'm not sure if you've heard of this medication or can help me understand what it might do to unborn child if, it has done this to me and others. They say things like these disorders can be genetic. I think by genetic makeup not really like metoclopramide ingredients. The doctor has told me p.s., this is irreversible
@@ralsharp6013 go to a doctor with your doubts they will be able to assess your needs and solve your doubts. They are the specialists in medication prescription after all!
There’s no actual understood science behind ssris and there’s absolutely campaign to get as many people on the pills as possible, for life if possible.
I have a question I have been off Zoloft and buspirone for over two months and it has left me with headaches almost every day and a weird type of vision issues. Have you ever heard anything of this?
Psychedelics are just an exceptional mental health breakthrough. It's quite fascinating how effective they are against depression and anxiety. Saved my life.
Can you help with the reliable source I would really appreciate it. Many people talk about mushrooms and psychedelics but nobody talks about where to get them. Very hard to get a reliable source here in Australia. Really need!
Yes, dr.sporessss. I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.
I wish they were readily available in my place. Microdosing was my next plan of care for my husband. He is 59 & has so many mental health issues plus probable CTE & a TBI that left him in a coma 8 days. It's too late now I had to get a TPO as he's 6'6 300+ pound homicidal maniac. He's constantly talking about killing someone. He's violent. Anyone reading this Familiar w/ BPD know if it is common for an obsession with violence.
I’m 56 years old I just started on SSRI and I always fought to try and manage it. I tried them recently at my wife’s suggestion and she was right and I feel much better and I’m very grateful and I encourage everybody who’s hesitant to do it. Take that leap of faith and just try.
I feel like doctors should be required to hand out a booklet or go over this information when prescribing antidepressants. I've been on Citalopram for years and didn't know about some of this.
What the heck?!???? I worked in a Psychiactric hospital, and I can’t even begin to tell you how blown away I am! None of our pharm classes included any of this information. We had numerous patients on The anti-psychotics mentioned here as well as the mood stabilizers, anti-anxiety meds you mentioned AND SSRI’s! How did the Psych doctors not catch this?!?? It makes so much sense as to why our patients reacted the way they did. I’m blown away.
Mood stabilizers and SSRIs absolutely CAN be combined, it's a reason for extra caution and the mania absolutely needs to be stabilized before trying, but it helps some bipolar people who are left with depression after stabilizing. This video oversimplifies massively.
My best advice to people taking any type of medication is to do research on it. Don’t expect the doctor or pharmacist to tell you much. It’s your body and you are responsible for your share. I’ve been on medication that messed up my bones and I learned the hard way, now I question everything.
what happened to your bones !?? I am also having ssri and I have problem in my bones like it feels stiff and uneasy everytime in my whole body ...plz help
That's all very well but if you have had a nervous breakdown you dont even know what day it is let alone cope with trying to figure out what can interact with SSRIs just a thought I know this unfortunately
@@streetridersidd1362 you feel restlessness and pain in full body,i think calcium levels decrease by taking these medicines. The way out is to take multivitamins and calcium supplements with ssris
Nobody told me long term use of anti-depressants can deplete the body of vitamins and possibly lead to thyroid disruption. After I was diagnosed with low thyroid, I was told I should have been taking a daily vitamin B.
Well Holly, maybe the doctor thought it would be obvious. Or maybe they just don't have time. It is annoying I know. But every medication has a side effect. Antibiotics really mess up and destroy healthy gut flora, which can lead to a whole host of other health issues. People should be taking B vitamins regardless of whether they had a course of antidepressants. If not done so already, I suggest you get a full blood test check what other deficiencies you may now have.
I've been taking Escitalopram since like 2017 and I am excited to find out what I have done wrong that I wasn't told about for the last four, going into five, years. That said, they have helped me a lot with regulating my mood issues and depression so even if I have made mistakes, they still have helped me.
Yeah I just found this video today and I'm kind of annoyed cuz I just got on another medication! Because I felt that the Lexapro wasn't working 😡 I swear everyone in positions of authority leaves out information
I had the worst side effects from this medication. I didn't even get to the full dose yet when i felt like i was gonna die. I literally got half of the side effects from the side effect list that comes with this medication. And getting back to normal took me a year. 10 days destroyed me, and a year to recover. My gynecologist was pissed that this medication is still prescribed coz of the side effects that it has on the mammary glands (that it just one of the many side effects i got). She said that she sees these side effects too often....
@@SpiritDragoness Oh dang, that is awful! I am thankful I didn't have bad side effects when I started taking them. I had a lot of worry about what if the meds were placebos and would I ever be able to stop taking them. I am over that now, but the worry and paranoia may have been a side effect
@@Yeah_You_Thought Or you may not have had a competent doctor. Having been an RN who trained at a teaching hospital for the local University, I am always wary of doctors who do not know enough and do not keep up on the most recent medical information. Sometimes, you can do your own research, or switch doctors.
I never knew that about NSAIDs. I knew about MAOs, St. John's, did not know about 5HTP. I'm surprised at how little of this was actually shared with me over the years, except for interactions with other SSRIs, because of needing to tweak meds in the past. Thank you so much for this video.
Micro doses about 100 mg of magic mushrooms also good for depression, or so I have read, and it also helps make new Neuro connections in the brain. But I don’t know if I can take them with my Ssri’s.
Some side effects can occur because of a reaction between 2 medications. I went for 2 months before it was discovered that the mix of one specific SSRI and another med I was on brought my blood pressure below normal levels. Neither of them had that listed as a side effect. So if that happens, notify your Dr. and see if that could be the case. It was not even caught by the pharmacist. I was on an MAO inhibitor ( Nardil ) for Post Partum Psychosis. SSRI’s did not yet exist. Nardil is a very scary drug, but I had no choice.
@@1978UA I have heard about similar studies and I appreciate that you're spreading the word about psilocybin therapy, but it is still a very relatively new science and I don't think science has had a chance to legally make these experiments accessible to alot of people that may/might not find alot of either pros or cons to that level of therapy yet. I like the prospects of the studies becoming more widely spread out, but there is still so much negative stigma surrounding the treatment because of the culture it represents. And as somebody that took mushrooms recreationally over the years, I'll admit that it's the culture that is often romanticized by the rec users that has made our science teams/government legislation boards full of doubt about the positive medical aspects and perhaps not taken these studies seriously yet. Idk, but I support the progression of that treatment the more we find out about it as limited as the clinical trials seem to have been in recent years.
@Touko Fukawa Talk to your prescriber about it! There's lot of medications out there, it could be you just need to be on a different one, or perhaps on a different dosage. But it IS a common issue with anti-depressants where it sort of... sucks things out of you? I guess? I'm not an emotionless robot, but it's harder for me to want to do something creative since I've been on sertraline. I mean I love not feeling like I want to kill myself constantly anymore, but I miss the days when I felt like drawing as well. But anyway like I said, make sure your doctor knows how you feel! You can discuss other options with them, whether it's just going with a smaller dosage or switching to a different med altogether.
I've been taking Celexa for over 20 years, 10mg/day for the first dozen or so and 20mg/day for nearly ten. Two years into initial treatment I read an article on SSRIs that listed a side effect of some as reducing migraine incidents. I'd suffered from migraines for over 40 years, never going a week or a month without one or occurring several days in a row at the same time of day or night. I realized I hadn't had one since taking the meds, and at 71 I still haven't.
John, have you ever heard of 'poop out' i.e. the idea that for some people it suddenly stops working (Paxil/Paroxetine) after many years, I suppose this can happen with other SSRI's, I sometimes worry about that and so tapered to a low dose of only 5mg but life is tough on 5mg, I tried 2,5mg and all manner of demons raise their ugly heads, depression, anger, sadness, worry, stress etc etc, this is my sticking point he 2.5mg stage. Im 55yrs so started taking it around 28yrs of age and was on 20mg as well initially, the last 7yrs tapered down to 5mg from 15mg (at some point I dropped 5mg) Ive read that the amount of serotonin circulating around in the brain lessens over the yrs of taking SSRI's, so Im not sure what this means the lessening of this pool of serotonin, does it then dry up eventually? The reason poop out is frightening is that 1. Depression will return with a vengeance and 2. Withdrawal or discontinuation syndrome sets in, wow - those 2 would knock anybody out. So I keep my drop to a minimum, but at times do wonder and think Id be happier on 10mg or even 7.5mg.
I ended up getting a rare side effect of sertraline: significant worsening of short term memory. It got to the point where, within the 5 months I took it for, I can only remember very few bits and pieces of the last 4 months before switching; everything is basically blank for me for the last 3 months, save a few horrible moments of emotional despair. Now I'm on escitalopram, with no signs of those side effects thank god.
@@rxndzvi yes, absolutely!! if it's impacting your day-to-day life negatively, that is NOT normal. Everyone's brain works differently, so if one medication isn't working for you, then there are many, many more to choose from. Keep your doctor in the loop!
I had serotonin syndrome for months because I'm a fast metabolizer and it was awful, but I didn't even know it was happening because I was never told any possible symptoms, thank you for this video
@Gretchen K. Adding to this: uncontrollable vomiting, sweating, shivering, dissociation, hallucinations. The few times it happened to me (caused by taking cough medicine) I remember being certain that this was how I was going to die. If my roommates hadn't been around to take me to the ER I probably would have.
I was prescribed Mirtazapine for insomnia about 2 1/2 weeks ago. One of the big side effects for me was the elevated edginess and anxiety it created. It's done a great job at fixing my sleep nonetheless. But as soon as my doctor heard me mention the side effects she quickly prescribed Fluoxetine. Never ever been on it. And after watching this and all the things to avoid I think I further want to stay away from it and just wait for these side effects to wear off. Personally I think sometimes these doctor rush to fix every little problem with a pill and expensive follow up calls and visits. We forget there in a business to push things that may not always be the right thing for us at that time.
thank you so much. nobody ever told me about these. I've been on antidepressants since 15 and I've always taken ibuprofen, and wondered why i would feel worse. so glad i saw this video.
I want to share my story so that others do not make mistakes. I suffered from serotonin syndrome after two weeks of taking Prozac, and then the doctor added another medication for me, which I took, and I had a panic attack, severe fear, and confusion, and I felt like I was going to die. I went to the emergency room in the hospital and met with another psychiatrist who had no experience. I told him, unfortunately, he said: I have anxiety that is not from the medicine. He gave me another medicine, so I believed what he said and I went into a coma due to serotonin poisoning. The medicine was withdrawn from my body, but I suffered from severe depression and anxiety after that because of this incident. I continued to suffer for years, and I am now fine, much better than before, and I am still recovering without any medications. An antidepressant. When I went to a psychiatrist, he went because I had a phobia of giving lectures at university only. I am very regretful and wrong for going to a psychiatrist. I lost 3 years of my life because of that.
No I agree, none of the doctors I’ve seen in the last 20 years and have prescribed most of these over the years, have never ever said a thing!! I’m Shocked!,!
I was only on fluxotine for a matter of 2 weeks, it made my migraines worse, I felt more depressed and anxious. I stopped immediately. I'm now waiting to be seen by a psychiatrist to see what therapy is best for me.
@@diplomasaurus4232 Because "feeling worse" is only temporary and the benefits are worth waiting for. The doctors should really state that the medication will make you feel worse initially though so it does not come as such a shock to the system.
I also had horrible migraines for the first couple of weeks, but on sertraline, and that seems to be quite common, especially if you’re already prone to headaches and migraines. But I’ve had that with every single SSRI that I’ve tried, and the side effect does go away for me after the third week. I really hope you can find something that works for you 💕
Fluoxetine takes longer than other SSRIs to start working - 6wks as opposed to 3-4. Feeling worse for 1-2 weeks (not 6-8!) is to be expected and they should inform ppl of that, but you shouldn't 'tough it out' if it's making you massively depressed or suicidal, and worsening migraines is probably a deal breaker for many :/ But it's quite possible a different SSRI would affect you differently, it's weird how different each can be for different people. (e.g. for me personally, fluoxetine is the only one that doesn't make me sleepy, oddly since that not very common for SSRIs, and lexapro/escitalopram was the only one I couldn't drink on.) Wishing you lots of luck, it's great that you're gonna see a psychiatrist!
I was put on anti depression pills when my son became ill, I was not depressed!!!!! But because I didn’t know where to turn I took them…. When he passed the doctor increased my dose and I was left to it…. No longer on them and so glad ….
Could I ask what your dosage was and how did you manage to come off that dose, who oversaw you coming off them and how long did it talk? I take 200 mg per day. I would be most grateful for any advice.
@@chintzyhall8731 I was on 150mg and reduced the dosage myself. Not really recommended to do without your gp’s say so but, I reduced slowly until I eventually stopped taking them. Side effects of the reduction were like fireworks going off in my head and was quite distressing at times. Guess the right thing is to ask your gp if you want to reduce them and be guided by their advice. Good luck
I know someone who was on venflalaxin and just switched to fluoxetine. This will help me help her during the transition. Knowing what food and over the counter medication to avoid is pretty important.
I’ve been on Zoloft for a few years now and I’m so happy with it. I’ve noticed that I can no longer take melatonin though. It makes me feel very jumpy and anxious.
@Drew Jackson Before that, a year or two prior I tried venlafaxine. I absolutely hated it: nasty bouts of insomnia, hallucinations, mouth so dry I could choke! Horrid brain zaps too. The comparison to my experience with Zoloft is like night and day, with the Zoloft I experienced some bad nausea and felt a bit uppity, but the change occurred within a week and the biggest thing is my mood has entirely stabilised. I initially went on it for anxiety reasons, so I'm not sure if that's why one didn't work, but my doctor did mention I had depressive issues as well. I don't want to off myself every day at least now, lol. I'm a far more pleasant person to be around: I'm not angry all the time, I don't snap at people, I'm way more inclined to show concern at friends being rude or off to me rather than lashing out and becoming vindictive. I feel like I have the potential to become a good person now. Nothing like that happened with the venlafaxine, I just became ten times more anxious and felt absolutely dreadful.
me too! for the longest time i was ashamed and very hesitant to take medicine. but once i started, it is like night and day in my general mood and ability to just complete everyday tasks. i am endlessly grateful for it. plus with the sertraline i have not experienced really any “negative” symptoms except a very occasional nausea.
@@jess57565 Basically the same for me. I have occasional nausea now, particularly with certain foods (particularly creamy, garlicky and mildly spice- used to be the worst for spice but I love it so much I soldiered my way through it) but it's 100x worth it!
My mum was prescribed mementine for Alzheimer’s disease and also sertraline, whilst she was in a care home. The ‘memory clinic’ kept increasing the dose she was on. From 25mg to 150mg. My mums muscles started to stiffen and we were told that sertraline and mementine shouldn’t be taken together.
If you think that the nurses in a nursing home understand medication interactions, I have a bridge to sell you. They aren't sitting there at the desk reading the latest nursing journals. They almost always have a h.s. education and couldn't wade past the index page.
So glad im off these meds now, been a couple of years since i had my last dose... there is hope for us all if i can get off these drugs then we all can.
I am on Prozac *for many years* and eat grapefruit occasionally. I have never noticed any increase in side effects. That being said, I only eat a 1/2 at a time. It's probably not enough to make a difference.
the esclipram has been great, except the 80lb weight gain, gas, etc. Since taking this my appetite has increased so much it is crazy difficult to resist... But seriously the anxiety is gone it does work. Im working on loosing the weight
i think it would be good to address that a lot of antidepressants can interact with marijuana and cause serotonin syndrome. because marijuana, especially when smoking it can encourage reuptake of serotonin. it only really happened to me twice both times i had smoked it and had consumed a decent amount. i can consume edibles just fine though so do what you will with that info
@@Purple_kiwi_ you're welcome i get mild serotonin syndrome but it can be dangerous if it gets to a more severe level. marijuana definitely has adverse side effects for some but obviously when used properly and safely and in ways that work for the person it can be great.
People also don’t realize that Marijuana itself is a stimulant, and can cause issues with other stimulants such as ADHD medication (Amphetamines). Can give you high blood pressure etc.
@@SleepySelkie96 omg i didnt know that, recently started taking methylphenidate and started on sertraline this week, i smoke a small spliff a day, i guess i should consider stopping then :(
@@nenee009 If you’re only smoking small amounts, you may be able to continue use. You just need to monitor your blood pressure since, adhd meds can cause higher blood pressure themselves. I’d talk to your doctor about it!
oh cool I've been eating ibuprofen like mad since December because of dental problems while on escitalopram. If you don't look it up yourself nobody tells you these things :(
I’ve benefited so much from mine but jeez, the sexual side effects are killing my relationship! I’m trying so many different things to get back to the love bug I was before.
Go see a specialist. There is a cream that women can use I think it’s applied under the arm or on the flank that helps even out hormone levels. I’ve always been a very sexual person and my wife doesn’t have quite the same drive. It’s been a bit of a struggle but recently a lesbian woman I know told me about this. Ssri’s are powerful drugs and can have many negative side effects too. Over the years I stay faithful through communication and a lot of masturbation but now I’m hopeful she will see a change back to our earlier years. Hopefully that’s not TMI lol.
@@lh98 not tmi. It’s reality. But my psych and I are working on it. Lowering my dose and adding a supplement that’s supposed to help with depression the same way SSRI’s do. We are trying that before moving on to different meds. I tried Wellbutrin and had a horrible reaction.
For me, it hasn’t affected my sex drive but has caused delayed ejaculation, which can be helpful…or not. For women I’ve heard that some ADs are designed specifically to address your concerns. Good luck!
@@BenSussmanpro yes! My partner had the same issue with the first couple meds he tried but luckily got it worked out. My dr immediately thought of Wellbutrin since it has no sexual side effects but unfortunately it sent me into a really deep depression and I had to stop taking it. What meds do you know of that I could try? I’ll bring them up to her. I have major depression, anxiety and ptsd. I’m on separate anxiety meds currently so I mainly need something to keep my depression in check. Of course I’m also in weekly therapy so I don’t rely on meds alone.
I have never had a patient have issues with SSRIs and NSAIDs, except one young lady who started having intermenstrual spotting when we started and SSRI for depression (she was using motrin prn for menstrual cramps.) Very interesting stuff! And great video, thank you!
not true movement disorders i got meige and blephorspasm from antidepressants made my life a living hell i been taking magnesium which has helped and i had to stop the dangerous meds so i can function i took alpha lipoic acid started 2 years ago for nerve pain to my supise they help alot more for my depresion then a few antidepressants i was on
I started out on Buspar then wellbutrin and finally in 2011 Quetiapine the latter was a life saver, I'm still taking it. Thankfully I haven't needed any of the other medications you pointed out. The video was very informative!
I love that you mentioned grapefruit. It actually slows down CYP450 too, which, from what I'm understanding, is a family (I think the cytochrome you mentioned may be in that family) of enzymes that metabolizes most antidepressants, anxiety medicine, and painkillers. None of those things will work on me unless I eat grapefruit, I had to figure that out on my own too after essentially experimenting on myself. 🙄 I ate half a grapefruit every other day and after 2 weeks I only needed a fourth of what I was originally taking. I went from still having panic attacks while on 2mg of Xanax (plus several other sedatives and medications) to only needing .5mg and I am now able to just use Kratom powder to prevent most panic attacks from happening. Grapefruit isn't super reliable though so I have a lot of trouble any time I'm needing painkillers. It's the worst at the dentist because they never believe me at first so they take forever and stab me so many times trying to numb me until they finally use a painkiller that is metabolized differently. 😑 All the painkillers that they've given me to take at home still won't work unless I take another 1,000mg of aspirin or acetaminophen too. I wish there was a cure for this kind of metabolism issue. Another person in my family has it too and it's just hell on us both. I believe something should be able to be developed from grapefruit to help people like us but it seems like it's a highly overlooked issue. Also, before anyone assumes I just built up a tolerance from recreational drug use or something. No, I have never used recreational drugs and I've been this way for my entire life. My son may also be that way considering ibuprofen won't even lower a fever when he's sick. It's an issue that a lot of people who carry the red hair genetic have apparently.
They won’t investigate and provide a natural cure because they’re too busy farming out their dangerous preparations.. Grapefruit could be the answer to a bucketful of problems.. I don’t trust the pharmaceutical companies at all.. take care out there, love from England..🌎 P.S. what is Kratom powder..? Thank you 😊
@@Fuzzysea693 I was born with strawberry blonde hair, so I do have the red hair gene. I have heard about the link between it and the issue with metabolizing these things too quickly. I just wish they would work on finding a treatment or cure for it. I don't think the scientists realize how serious it is. 🤦🏼♀️
Psilocybin containing mushrooms saved my life. The drastically reduced my benzodiazepine withdrawal allowing me to quite illicit pill addiction after three years of heavy daily use before it would had became medically dangerous to quit. It has also helped me survive depression.
@Lillian Victoria I was having this constant, unbearable anxiety due to work stress. Not until I came across *dr.jeromespore* a very intelligent mycologist. He saved my life honestly
@Vicky Desmond I feel the same way too. I put too much on my plate and it definitely affects my stress and anxiety levels. I am also glad to be a part of this community.
drinking alcohol on fluoxetine almost got me hospitalized twice. drinking alcohol on escitalopram is perfectly fine for me and i can drink as much as i could without meds. fluoxetine had a shitton of side effects for me, escitalopram has none. for fluoxetine, i could only take the lowest dose (5mg) and for escitalopram i'm on the hightest dose (20mg) with no side effects. i love escitalopram. maybe you can tell.
ive been taking fluoxetine since december 2020 and i did not know i was not supposed to drink alcohol and it also made me lose control so much faster and not in a good way. It also fucked up my moods and did not help me
I got lucky and I only have one negative side effect from Fluoxetine. Dry mouth. Brains are whacky, and SSRIs are relatively new. The workings of the human mind are still being evaluated by medicine. Don't be afraid to tell your doctor that an antidepressant isn't working for you. Every individual is different, and having so many alternatives means doctors can try out different ones and figure out your best option.
I can drink very heavily on Fluoxetine - and I'm on a high dosage - and be completely fine. It's so weird. I've been very lucky. Alcohol does make me dizzy quicker if other stuff is involved. Like at gigs, when I drink and I'm jumping around and yelling. I nearly pass out but sat and drinking, I can drink loads and be fine. I think I've personally been really lucky with Fluoxetine. It's really really helped and caused near to no side affects. I know you're not sht talking Fluoxetine but when people tell people not to take it, that makes me really angry. Yes it works for some and not others but you just keep in close communication with your doctors and tell them immediately if you have problems.
I don't usually drink often anymore, maybe one night every month or two, however I've noticed on sertraline I am utterly bladdered after 2 or 3 drinks :s I'm usually a "lightweight" but now I physically cannot binge drink on a night out or "keep up" like I used to, probably a good thing tbh but I wonder whats going on there.
man ive been on paroxetine for about 10 years now and was never talked to about which foods/drinks to avoid- i guess its a good thing i never liked grapefruit 😂 thank you for this video! its absolutely wild how much we know about brain and body chemicals now; wild but wonderful
I've tried Fluoxitine, Sertraline, Escitalopram, Duloxetine, Venlafaxine, and Buspirone. None of them worked for me unfortunately. I just started Vortioxitine and Abilify. I'm really hoping they work. After trying the first 6 meds I tried to go unmedicated and my depression got more severe mostly due to life circumstances but I realized I need medication. This was a great video, thank you!
I had treatment resistant depression so I also tried several until I was prescribed ablify with it. Turns out I have bipolar and since treating that it’s helped so much
No one told me that I should be careful taking ibuprofen with sertraline. 6 months ago I had a hip replacement at the age of 58. I had been taking sertraline for 8 months and ibuprofen for about 12 months due to hip pain. Before my hip replacement I wasn't told to stop either of them and after my hip surgery I needed a blood transfusion because during the surgery I had lost so much blood. 🙄
You should have been told to stop certain medications during your pre-op office visit. Most if not all surgical offices give you literature on what medications to stop taking.
@@jeanettepaynter1183 I should have been told but I wasn't 🙄. No mention of either medication in the folder . They did tell me to stop other meds but not those 2.
What's crazy is that nobody told you to not take an NSAID daily for months! That's absolutely not safe, and yes they def should've informed you to quit before the surgery, so sorry that happened to you. Acetaminophen is the only OTC pain med you can take longterm (as long as you don't exceed 6-8/24 hrs and your liver is ok.)
@@Suzanne4415 it was fine to take ibuprofen long term as long as you take no more than 2 three times a day. My GP told me to take them with cocodomol. I couldn't walk without them before my hip replacement. 🙄 .
I don’t miss alcohol since there’s plenty of non-alcoholic beverages to enjoy. But DAMN… I miss having grapefruit!!! 😢 It’s worth it though to be able to function without having a meltdown every day.
I was doing good until the ciprofloxacin lol. I take cip for regular UTI's. Good to know this though. Also when my doctor was doing research for the right anti depressant for me as I'm a fair amount of medications. He mentioned that when taking sertraline with tramadol it can also lower the blood pressure.
I was seeing a doctor while trying a new SSRI (I think it was citalopram) and he prescribed me Sumatriptan for my migraines. I was in the office while he said he was going to prescribe it and I went "wait, isn't that dangerous? Both medications have huge warnings of not to mix." He said it'd be fine and not that big of a deal. I never went to that doctor again, and didn't really need an antidepressant at that time. Even the pharmacist was like WTF, no.
I was prescribed Sumatriptan while on Escitalopram once too. I had no idea they shouldn’t be taken together and was never warned about it. Luckily for me, I did find out that you shouldn’t take the former if you have epilepsy (which I do.) so I never did. For some reason the information about me having epilepsy wasn’t marked down in my record @_@
I'm increasingly a big fan of running new meds past the nearest pharmacist as they're super knowledgeable about interactions. Glad you knew to ask about that particular combo!
My nurse prescribed me lexapro after tapering off zoloft but didn't say anything about waiting any time between medications. My pharmacist said I couldn't take them within 5 to 7 days of each other. He wouldn't even let me have them because he wanted me to be safe. My nurse didn't tell me any of that. Just added to the list of reasons I need to find a new place and a real doctor. Thank God for pharmacists!
this all makes so much sense. i was on zoloft (setraline) from 8th grade - summer of junior year. they moved me from 25mg-100mg over a few months and i was acting out so bad. had no idea why but i was all wacked out. i was starting to drink and obviously was on antibiotics when i was sick and would have such weird reactions. same with advil. my junior year summer my moms insurance was dropped and i had no access to meds. all of 12th grade i went cold turkey and not having a great year. had brain zaps for a year after that. i was acting reckless and doing anything without serious thought and gave no sh!ts and was seriously unhinged. i would cry and freak out and be so angry my skin would crawl with disgust at literally everything. had so many fights with my family and boyfriend like damn i was so mentally unstable from setraline's side effects. i had absolutely no idea until now and just thought i was crazy.
Jada, I truly hope you’re doing better. What a horrible thing to have to go through, especially as a teenager! My 14-year-old daughter went through hell the past 18 months. They tried out several different antidepressants, then finally she got on Zoloft and it’s really helped her out a lot. 🙏🏼
That’s so awful for a teenager to have to go through med withdrawals because of insurance! I’m so sorry that happened to you, and I hope you’re doing well 😔💖
Btw, when a physician prescribes medications they know the risks and interactions between all meds that they are prescribing. So they weight the pros and cons to each med. They make an informed decision and weigh the risks. So most time you are taking meds that interact with one another but not to a significant degree that will affect you. That’s why people don’t die left and right every day.
This. There’s no harm in asking to make sure your doctor is aware you’re on everything and has considered it, but things *can* be used together safely if done with an awareness of dosage and side effects and so on. I’m on an SSRI for PTSD and I take Tramadol for autoimmune arthritis pain management and I have done for years.
while this IS true - they are still human. I had an incident with a new medication that the *pharmacy* staff picked up on that shouldn't have been prescribed with other medication I was already on. my doctor did NOT pick up on this.
@@juliaconnell To be fair that is exactly what pharmacists are for. ETA: she is right that *physicians* will not always be 100% on top of all interactions & their respective risks, as stated in the comment she replied to. Didn't mean to be dismissive of the fact that they messed up hers & she suffered for it. (But they still are a lot more so than many people think after watching this.)
well, they should know. Unfortunately, the ones where I am have pretty consistently prescribed medications that are not meant to ever be used together, including giving someone a MAOI right after a SNRI, in the same day... (which should NEVER be mixed and this patient did not make it) While I agree, most doctors know what they are doing, it's still good to be careful and double check with your pharmacist if you have any questions as well.
@@meztlistormheart2636 i was giving the reason why they don’t tell patient all of this. And again I will mention. You weight the risks and benefits. And if the benefits outweigh the risks, it will happen.
Damn i didn't even know Cipro can interact with SSRIs. I'm on zoloft, quetiapine, mirtazapine and lamotrigine. Used cipro for about 3 weeks along with other antibiotics. I guess i'm lucky i didn't develop SS
@@jjmedicine Let’s imagine “a friend of mine” having taken Paxil for 17 years. He quit alcohol in 2009, nicotine in 2011, just finished tapering off of Klonopin, after 31 years, and is considering a slow taper off of Paxil. There’s no intention by him to ever cease lithium or bupropion. He’ll be discussing this idea with his doctor during his next appointment, in a couple of weeks. He’s 50+ and recently began studying Paxil and learned something he never expected: that it’s notoriously hard to quit. It’s my understanding that he’s pretty nervous. Is there anything more he might learn?
Am enjoying these videos as they are clear & your use of the screen with bullets in your outline form are visually helpful. One suggestion: the use of the yellow heading was very difficult to read against the white background; so the more faint colors are not the best choice, as seen in the topic header: TCA Antidepressants... Thanks!
It’s flat out WRONG to suggest that discontinuation syndrome occurs only when you suddenly discontinue SSRI. I suffered severe discontinuation syndrome DESPITE carefully following my doctor’s instructions when discontinuing Paxil. This situation didn’t simply affect me, so much so in fact that class action lawsuits have successfully proceeded against Glaxo Smith Kline (manufacturers of Paxil) precisely because of this and other problems with this medication. You should have been more clear that no matter how gradually you decrease this medication, you may STILL suffer discontinuation syndrome. There are people who haven’t been successful in ceasing Paxil, because of this problem.
I started SSRIs recently and had grapefruit 2 days in a row. I feel awfully tired. This video explains that. However it got me to look into the long term affects of SSRI’s which makes me want to wean off them as soon as my 30 tablets are out
Get off them and instead take psilocybin (magic mushrooms). It has helped with my depression and anxiety. No side effects or withdrawals like anti depressants. Trust me
So, when I was on abilify, quetiapine and SSRI I drank 0.5l fresh grapefruit juice while I was waiting in line in a restaurant and I almost fainted. Low blood pressure. Fortunately, I don't take most of it anymore.
I use to be on Zoloft. I was still depressed and I constantly got high fevers. All I was told was don't drink alcohol. I wish they had told me about these other risks. Maybe my regular taking of NSAIDS, Antibiotics, and Anti-emetics caused the fevers, anger, and stomach pains I had on Zoloft. I wish doctors would just be honest I've had so many tell me drugs are all no risk, you can mix anything, classifying addictivedrugs as non addictive.
@@Cathy-xi8cb You are absolutely right. I know that now. Unfortunately sometimes you can't just trust anyone because they are supposed to be a professional.
@@jazzmyne6881 I am a licensed medical professional, and I can tell you that no prescriber has the time to review everything with you anymore. No one was being "dishonest" with with you, because they are thinking only of warning you of deadly reactions, not the ones that make you miserable. Most prescribers also specialize, meaning that they cannot possibly stay current in every area of advancement outside their specialty. Pharmacists might guide you, but not after COVID turned them into vaccinators in their "spare time". The only answer is to look up every medication, every condition, and start to learn as much about things as you can, every time, every situation. And try hard to stay off all medications if there is another effective way to address your condition(s). As providers, I can assure you that this is what we do for ourselves and our families. We aren't fond of drugs because we know so much about the complexities. We will take them very mindfully when the alternative is more illness, injury, or death.
Stopping Paroxetine was awful (took 3 months). Rapid increases in dose may cause Serotonin Syndrome but this risk is normally pretty small. You are more likely to suffer other side affects like headaches, nausea. Fever is a concern. Grapefruit interacts with a ton of medications. Most antidepressants have very little interplay with it. The mentioned CYP3A4 Enzyme is actually a whole family of enzymes. Unless you have a bad gene for the right version of an enzyme to metabolize your drug it is unlikely to affect you. Genetic testing is available affordably for this type of interaction. St. Johns Wort is a serious risk. There may be a genetic component but it is very common in serotonin syndrome cases. 5-HTP is a serotonin precursor. It doesn't tend to interact unless people have rarer genetic conditions or are on TCAs/MAOIs. Most Tryptophan gets destroyed in the stomache. It is not stable in Acids. Bio-availability is normally 40% or worse. Lots of medications interact with the CYP enzymes. Expect your pharmacist to notice as their software and training is to look for this; your doctor likely will not. This is why it is important to try to use the same pharmacy. It is really bad to mix different types of anti-depressants without supervision. I currently use two. I am fine. But there is a real reason to be concerned otherwise. The TCAs and MAOIs are especially dangerous.
What are your credentials (not challenging, I just spend a lot of time on random science videos like this one and I like reading the comments. Sometimes you come across R&D scientists for pharma companies, sometimes you come across the PhD who helped characterize an enzyme. You just seem to know good stuff)
You are lucky you could get off, it seems to me that the longer you are on it the harder it is to come off, its like it becomes a part of your brain and trying to stop it is like literally taking a chunk of your brain away, the brain will rebel and do anything to get it back.
I asked basic questions that I thought were important like "can I drive?" "are they addictive?" etc Never thought about grapefruit or any kind of straight forward staple that one could accidentally consume without knowing it could cause problems. These seem to be prescribed very readily in the UK to anyone who says they feel anxious. Kinda glad in a way as I would never have pursued it if it was going to be a whole consultation before I could get them. They've helped massively.
Wow. I have fibromyalgia and also take Sertraline for depression - and I’m on several other medications that all increase risk is serotonin syndrome- now I just need to find myself the will to not convince myself I’m at deaths door 😂😂
@@Haddy26 hey - it’s the kind of rule everything else out type illness, I was referred to a rheumatologist who did several tests and came up with the diagnosis
@@sleeplessinscotland2578 I've been having severe fatigue, no energy and muscle aches for the past week, and it's happened off and on a month ago as well. I figured it's just a side effect of my depression and anxiety but I'm wondering if it's something more.
As an advil taker with severe anxiety I'm waiting on this ad to end so I can have a nervous breakdown learning about why I can't take advil with my sertraline. Idk why I do this to myself 😭
@@nola3724 the hypermobility is genetic, I don’t think it has to do anything with the meds. I have always been fatigued. I just didn’t know what caused it because I didn’t get diagnosed with it until I was 30. The doctors just explaind it that it was all in my head because mental issues and I had antidepressives. But maybe it’s good to get to the core issues if you have any other problems involving sleep.
I'm on Peroxetine, I've been on it for years now, and have never been told not to eat certain things, maybe that's why I feel like it's not making difference, I still feel like I'm trying to run in water, lost count of how long I've been on it now but Docs are reluctant to change it.
Paroxetine works. It works very well actually. I’ve been on and off antidepressants since my teen years (I’m now 37). I tried a few and found paroxetine 40 mg works best for me. Through the years I got off to give myself a break and also because of pregnancy. It was prescribed to me for major depression, social anxiety disorder, and PMDD. It did wonders! And still does! But the one and only thing I can say about paroxetine is getting off and going through the withdrawals. They are no bueno. Even tapering down ever so slowly the withdrawals were still there. But just look on the bright side, the symptoms wont last forever although very miserable you will get through it 👍
@@NurseRay Did you need to come off of Paroxetine completely when you were pregnant? Or just lower the dose is okay? I’ve been on Paxil for 5 years and I want to get pregnant in 2-3 years. But I am afraid of coming off. I was on 20mg but not I lowered it to 10mg.
@@valeriemorel3708 oh dear my apologies for the late response! But to answer your question, I DID NOT get off completely. I tapered off kinda fast (which I DO NOT RECOMMEND). When I found out I was pregnant I immediately reduced my original dosage 40 mg down to 20mg. I gave it maybe 5 days then down to 10 mg for another 5 days and then finally down to 5 mg for 5 more days. It’s advised to taper much slower (like for weeks/months. BUT since I actually got pregnant I was not about to put my baby’s health on the line. So yes it was a HARD RIDE DOWN😵💫. The withdrawals were definitely present. For the withdrawals I used Benadryl to ease the discomfort like (brain zaps, fatigue, headaches, just plain yucky feeling). I have used paroxetine since my teen years. I’ve tried to go natural with OTC supplements vitamins, herbs and even therapy. But it has always been Paroxetine that does the job. I also have MS (Multiple Sclerosis) and believe it or not, paroxetine helps with nerve discomfort too. After arrival of my son I tried Cymbalta for one whole year (my neurologist recommended) and it did little to nothing for me. My chronic nerve pain and depression was still very present. I developed PPD (Post Partum Depression) really bad. So I was bumped up to 120 mg of Cymbalta (the highest dosage). It worked for maybe 2 weeks and still I was not myself. So I finally told my Dr that I want to switch back to paroxetine and indeed after about a month (20mg) 2nd month (30mg) and finally the 3rd month (40mg). Right now I can say I’m feeling like my old self again (pre-baby). I’m less anxious, and my depression has vastly improved compared to taking Cymbalta smh. Anyway, I hope what little advice I provided will help you. Just make sure to taper down. It’s brutal but you will get through it! *hugs* ☺️
My doctor has prescribed me Naproxen long term for arthritic pain and he never once told me it would interact with Escitalopram, which he also prescribed me long term!
My mom has kidney damage from all the meds she's taken over the years. When she went to a kidney specialist, the first thing he said was to stop taking Naproxen. Of all the meds she was on, he said that one was the worst.
@@jazznpercy - I've got RA and recently had a really bad attack my GP gave me Naproxen - I thought I was going to die nearly ripped my digestive tract out
Thank you so so so much for making these videos. Im subscribing immediately. My most recent diagnosis was functioning neurological disorder as the cherry on on top of my fibromyalgia and list of mental illnesses. I'm used to Avoiding learning about fibro since it takes hints if I hear symptoms I don't have like shaking as i do now, but I'm being heavily encouraged to research FND. I'm very much going to watch closely in case you may cover it as you've covered fibromyalgia and lupus so well. You teach wonderfully. God and 0r whatever power or not bless you. Thank you so much.
It's like the doctor asked me if I felt any side effects from rizatriptan & escitalopram, but I was like, "yeah probably but anything is better than a full blown migraine."
May I ask you guys a question, here goes > Did you guys start having GERD or acid reflux after taking an SSRI? I started having reflux after a year and was put on a PPI, to stop the acid and been n that since, I think SSRI's have an affect on the LES or sphincter of the stomach or the opening or flap that allows acid to reflux back up into the esophagus thereby, giving the acid reflux sensations. I did see a study on it, that SSRI's relax the LES, and foods that make you feel relaxed or happy like chocolate or chamomile actually increase Serotonin but also relax this LES as well.
@@quinn799 Yeah, I only started taking acid reflux meds after a year on Paxil, only recently, a few yrs ago found a study that suggests this, like 25yrs later.
Add valium to the list, paroxetine + valium can just make you unable to breath, and reducing the usage of valium takes very long and is really hard to endure.
They actually use the Grapefruit fact in an episode of Moriarty the Patriot. After hearing that a gardener was being abused by his employer, the Moriarty brothers visit the employer's estate, and notice he has many exotic plants, including a grapefruit tree. They receive an invitation to meet with the employer, and mention that the grapefruit has an excellent taste. He has the servants make juice out of it, he drinks it, and it counters the heart medication he had been taking. No one raises a hand to help him, and he dies. It's episode 2, so you don't have to go far into the series to see it.
SSRI worsens my depression tremendously. Whenever I try to use them, I have SI, life loses all value, I cry with deep desperation, and think about staying under the bed. It's one of the most terrible experiences I always have in my life. The worst of them is Prozac. I keep them very far from me now. Thank God this inferno is reversible. I notice it lower my creativity too. Terrible, just terrible. 😮😮😮
Screw fluoxetine man, made me so much worse. I take mirtazapine because I also got diagnosed with anxiety that is somehow far more severe! So I'm just glad it works, thank goodness for modern medicine- and I mean modern, mirtazapine is the new kid here.
In the US, Escitalopram is Lexapro, not Cipralex. That's what it's called in the UK. I've been on it for years and have never had any issues with any of the stuff he mentioned.
No SSRI is meant to be used for years. You are poisoning your entire body and brain. If you go off you will experience worse withdrawal symptoms than heroin… so slowly decrease the amount you take over a 6 month period.
I have been on 5 HTP , melatonin , Gabatropin & GABA and progesterone , estrogene cream and L athyrosene ( dopamine ) for almost 18 years till 8 months ago ….I couldn’t get up anymore …severe panic attacks , social anxiety and definately depression and PTSD …..after thinking that I need thyroid medication my dr said I actually need SSRI & put me on Serdep ( Zoloft ) ….after taking meds for 3 days I was a different person …..I regret have not believed in any meds all these years as I am a “ better “ person now …..working as a clairvoyant medium healer , yoga teacher ….I have compassion for self and others again and don’t suffer these absolute terrible panic attacks and anxieties anymore …..I have never slept a lot as I always was highly strung , highly creative and have had lots of energy ….now I am just a bit more chilled but the extra seratonin has also stopped my hair loss , dry skin , no voice , dizziness , vertigo etc etc …..I will not go off this beautiful blue pill any time soon lol 😉😊😁😂
Holy crap! It's safe to say that just about every substance, RX, food, etc... that one could consume would cause a problem. I think I'll look for natural remedies for my SAD.
Pot...medicinal ....in my state it's legal I take the tinctures with high CBD and I came off my depressant and anxiety meds altogether...CBD at the very least is also a good option over the counter brand hemp bombs is best...street pot isn't the same as the dispensary stuff no matter what anyone tells u
No, really no. You took the wrong message because you're the wrong audience for this info [ETA: and it's honestly not stated/explained well here]. Grapefruit is a problem with almost any drug, NSAIDs carry some risks for anyone (be extra aware or just stick to acetaminophen/paracetamol). No doc on earth would dream of putting you on an SSRI and an MAOI, or tricyclic. You're not gonna just be randomly downing antipsychotics or lithium one day. And the vast majority of SSRI takers have no (additional) problem w/ drinking.
Basically everything has the possibility of causing interactions, whether you're using prescription meds or natural remedies. I've been on SSRIs for over 8yrs now and I've never had any problems aside from a higher dose causing some brain fog, so I went back down and was fine. I eat grapefruit all the time, take ibuprofen for pain, and drink alcohol and haven't had any problems. Wish he would give some statistics on how rare it is for these interactions to actually happen. Don't rule out prescription medications just because theres a possibility of side effects.
This is a really really good channel! So much information that isnt commonly known but is very important! Thankyou for your excellent explanations and descriptions! Cheers!
One time, about fifteen years ago, my former doctor and also former pharmacy had one heck of a time communicating, and I wasn't as on top of my medications as I am now. I ran out of Celexa, and was out for close to a week. It got to where I was crying uncontrollably and feeling really terrified of my emotional state. I ended up calling the doctor on call to get the stupid script filled. Never. Ever. Again. It was hell. Don't do it. Skipping a day by mistake now and then doesn't seem to affect me (this is extremely rare), but there's a reason they say to never just stop taking SSRIs. Maybe this is true for SNRIs as well? I'm not sure. I'm on two antidepressants, but with doctor supervision, and no ill effects.
You missed out pain flower, many depressed people on SSRI try this for sleep but can give you serotonin shock syndrome and should be avoided completely.
I was on paroxetine for 15 years. For SIX years I struggled with sleeping 12-15 hours a day! I could sleep 7 hours then fall back to sleep for 8 hours more.. The doctors & specialists couldn't figure it out why. I went gluten & dairy free for a year. I underwent many tests & different drugs, which had their own side effects, to figure out why my sleep was so messed up. None of this helped. It was debilitating. Everything around me was falling apart . I couldn't take care of my house or yard. The doctor didn’t taper me off just switched to another drug with the same issues. I also was on nsaids & opiates for severe arthritis. For several weeks after stopping the drug I experienced daily throwing up, diarrhea, brain zaps & daily weepiness. The withdrawl depression was so much worse than the original depression . It's been 10 months since stopping paroxetine and the the weepiness continues. Imagine that your feeling ok and talking to someone about something mundane like the weather and quite suddenly you're fighting off tears & sobbing for no reason. I've become more reclusive as this is very embarrassing. I did find out that paroxetine shouldn't be taken for more than 2 years. I also suffer from migraines & hashimotos. The drug had zero effect on the migraines .There has to be better treatment for depression than these drugs. Medical cannabis has worked better for me. The doctors prescribing these drugs don't really know in depth how to prescribe these drugs or how to discontinue their use. There are some people who have to taper off these meds FOR YEARS! Imagine enduring negative side effects from theses drugs and having to taper off for 3-4 years. If you doubt my experience just check out Facebook pages for support for patients trying to stop taking these drugs.
I can confirm what she said is TRUE. I was on Paxil for 3 years and had withdrawal symptoms for a year and a half. Horrible HORRIBLE side effects and withdrawals. Never again am I going back on anti depressants. I have been taking psilocybin instead and has helped me so much with my severe depression and anxiety. No side effects, withdrawals, or addiction. Best part about it is all natural mushroom. I suggest to start microdosing them. Take them at small amounts at a time because too much will do the opposite and you will have a negative experience.
I've been on Lithium, fluoxetine, and a few other things for years. I was recently told of this negative interaction, and it turns out that there's only a risk if I wasn't taking it regularly. It's interesting the way these things work.
The logic amazes me don't take these things because they make too much serotonin.....but take this pill that makes what little serotonin you do make work longer (less reuptake).
Caffeine, nicotine, added sugar, and dairy. These are the things that'll cause my side effects and drive me into massive paranoia. Thanks for the information. Also there's caffeine in chocolate. The more ya know.
Thanks for sharing. I wanted to mention chocolate has very little caffeine, but you can add cocoa powder to anything. The problem with most chocolate is the amount of sugar it has. The darker the chocolate, the less sugar and dairy, but the more caffeine. Just keep in mind a whole dark chocolate bar has less caffeine than a cup of coffee.
Most of the people watching this aren't neuro scientists. It would be great if you or someone else could explain these medications in a childlike way so that we understand a bit easier.
After a horrible experience at LAX I started experiencing panic attacks daily I finally broke down and went to the dr who put me on Lexapro. After only 3 days on 10mg a day (low dose) I started experiencing serotonin syndrome. I hadn’t even heard of this or knew about it. Be careful some people are extremely sensitive and can’t take SSRI at all
Hello what are the symptoms of this ? can you tell me I hope you can see my comment and answer thank you God bless you I'm taking escilatopram too recently
thank goodness i rarely drink anyways, but i totally noticed when i drank after starting my medication that i was so SLEEPY like right away! it ruined my fun nights when i was too tired to function so i usually am the DD nowadays haha. kinda sucks tho...i wish i could get crunk every once in a while without worrying about the affects
Psychedelic’s definitely have potential to deal with mental health symptoms like anxiety and depression, I would like to try them again but it’s just so hard to source here
Psychedelics are the reason why i didn’t take my life when i was at my end. I was stripped of my ego and saw the beauty of life and interconnectivity and even though i still battle anxiety and depression, I’m doing better everyday and will never think in such a self destructive way again.
LSD and mushrooms completely changed my whole outlook on life. I became a better version of myself This experience gave me a lot of confidence about my self and my body. A bunch of bad thought / behavior patterns were broken. One of these was pretty bad OCD that made me wash my hands a lot. It gave me a lot of hope that things will be fine, this is the one thing that I heard throughout the trip: Everything is alright. The main reason for the trip was my severe depression and it definitely helped me (although it's not gone). Before all I could do was lay in bed. Now I am trying to rebuild my life one step at a time which wasn't possible before."
Good lord Im glad I found this channel it was like was gods plan. I have some of those medications that increase serotonin syndrome risk and Im glad I didn't take them. Im going to talk to my pharmacist and see if there are other interactions because I have a lot of medications.
I'm on Lexapro 20MG and been robotrippin on DXM for a while. Good to know that I need to be a bit more careful. Currently the only affect I get from mixing the two is an upset tummy but I believe that's linked to seratonin syndrome
as someone who did the same thing in his late teens for about a year I will leave you this warning. it has caused me permanent neurological damage (I'm 33 now). don't mix ssri's and dxm
Dxm caused me permanent visual disturbances that have lasted 20+ years from a single dose of 420mg. I was 15 and on no meds. I had/have done many other drugs before and after - nothing ever affected me as negatively as DXM did…just stop. I’m not “anti drug” at all just “anti DXM”
Thank goodness we have medications like SSRIs. My quality of life is better. If i had of been sick 100 years ago, I would have been locked up for life.
Same. I read the interaction warnings on supplements or Google it. Most herbal supplements will react negatively with SSRIs.
I think this all the time! We wouldn't even be locked up if it was 200+ years ago, stoned and burnt!
Yeah. Nothing like taking a pill to numb your troubles rather than addressing them
@@urfavegemini4231 i don’t think they were stoning people for turning self pity into a full time job.
@@eclark9965 The pill is supposed to give you some energy so that you can actually address the problems. Like push starting a car with a dead battery so you can take it somewhere where you can fix the problem.
I feel like, especially these days, everybody is struggling with mental health and could benefit from careful/ intentional therapeutic use of substances like these.
This whole thing is pretty new to me, can I contact nhr_syndicatee for guidance? If yes where please
@@julianwan1140 Yeah mate @ nhr_syndicatee
@@julianwan1140 inSta app
@taiscaptures They ship anywhere and discreetly.. that's if you're worried about that
I've been on SSRIs for almost 15 years. I wouldn't even recommend these medications to my worst enemy. Very little is known of the extent of the long term effects on the brain. Over the years my symptoms has just gotten worse and it's extremely hard to quit because of the severe side-effects it causes. Dizziness, electric shock sensations in the brain, anxiety, depersonalisation, sweating, balance problems, trouble walking, nightmares etc. The list goes on and on and on. This is a 40 year old medication and now just serves as a massive cash grab for the pharmaceutical companies. Recent studies show that serotonin might not even be linked to depression after all and that SSRIs are pretty much as effective as a placebo for treating mental illness. There will come a time when we look back on SSRIs the same way we look back on the medical use of heroin, cocaine and methamphetamine today.
Wow! No doctor has ever mentioned this when prescribing meds.
I agree
I know! It says on the pharmacy notes not to drink on it but that’s it
Never told this and I take one.
Right. Don't trust your Dr for this info. Talk to your pharmacist. He's your friend!!!
Exactly this is crazy
As a neuroscientist, I find this very informative. You were able to catch a lay audience & as a registered nurse who studied neuroscience in my doctoral program, you did a great job explaining this. Thanks!
Are you still studying and can you help me understand why my Tourette's has come back (after 40 years of not having any tics.)
They're calling it rare TD now, after I received a Maxolon for a migraine. I've looked up tardive dyskinesia. And it seems like that could be the case, however, it also feels like Tourette's because I have exactly the same motor tics I had when I was 13 and younger.
Toes, shoulder, eyebrows, bubble feeling under my top lip. Also my back and legs Twitch all night..
Ok so the biggest reason that I would like to speak with somebody who might understand this whole serotonin and dopamine thing, is because this is the medication that they give to pregnant women for nausea. It's not recommended in some countries for children under 10 due to the nerve damage side effects. Yet recommended for the foetus.. I'm not sure if you've heard of this medication or can help me understand what it might do to unborn child if, it has done this to me and others. They say things like these disorders can be genetic. I think by genetic makeup not really like metoclopramide ingredients.
The doctor has told me p.s., this is irreversible
@@ralsharp6013 go to a doctor with your doubts they will be able to assess your needs and solve your doubts. They are the specialists in medication prescription after all!
@@azulyraazul9287 thanks, yes have done that
There’s no actual understood science behind ssris and there’s absolutely campaign to get as many people on the pills as possible, for life if possible.
I have a question I have been off Zoloft and buspirone for over two months and it has left me with headaches almost every day and a weird type of vision issues. Have you ever heard anything of this?
Psychedelics are just an exceptional mental health breakthrough. It's quite fascinating how effective they are against depression and anxiety. Saved my life.
Can you help with the reliable source I would really appreciate it. Many people talk about mushrooms and psychedelics but nobody talks about where to get them. Very hard to get a reliable source here in Australia. Really need!
Yes, dr.sporessss. I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.
I wish they were readily available in my place.
Microdosing was my next plan of care for my husband. He is 59 & has so many mental health issues plus probable CTE & a TBI that left him in a coma 8 days. It's too late now I had to get a TPO as he's 6'6 300+ pound homicidal maniac.
He's constantly talking about killing someone.
He's violent. Anyone reading this Familiar w/ BPD know if it is common for an obsession with violence.
Is he on instagram?
Yes he is. dr.sporessss
I’m 56 years old I just started on SSRI and I always fought to try and manage it. I tried them recently at my wife’s suggestion and she was right and I feel much better and I’m very grateful and I encourage everybody who’s hesitant to do it. Take that leap of faith and just try.
I feel like doctors should be required to hand out a booklet or go over this information when prescribing antidepressants. I've been on Citalopram for years and didn't know about some of this.
They don't care. They want you to stay sick.
Always google before taking anything I’m prescribed.
It's usually in the leaflet that comes with the medication. I've been on it for years too (20+).
You want people to read??? @@threeMetreJim That would be sensible.
They should prescribe meds for stupid people who can't read @@lazyhippie6139
What the heck?!???? I worked in a Psychiactric hospital, and I can’t even begin to tell you how blown away I am! None of our pharm classes included any of this information. We had numerous patients on The anti-psychotics mentioned here as well as the mood stabilizers, anti-anxiety meds you mentioned AND SSRI’s! How did the Psych doctors not catch this?!?? It makes so much sense as to why our patients reacted the way they did. I’m blown away.
Mood stabilizers and SSRIs absolutely CAN be combined, it's a reason for extra caution and the mania absolutely needs to be stabilized before trying, but it helps some bipolar people who are left with depression after stabilizing. This video oversimplifies massively.
My best advice to people taking any type of medication is to do research on it. Don’t expect the doctor or pharmacist to tell you much. It’s your body and you are responsible for your share. I’ve been on medication that messed up my bones and I learned the hard way, now I question everything.
what happened to your bones !?? I am also having ssri and I have problem in my bones like it feels stiff and uneasy everytime in my whole body ...plz help
That's all very well but if you have had a nervous breakdown you dont even know what day it is let alone cope with trying to figure out what can interact with SSRIs just a thought I know this unfortunately
@@streetridersidd1362 you feel restlessness and pain in full body,i think calcium levels decrease by taking these medicines. The way out is to take multivitamins and calcium supplements with ssris
@@catclaw7462unless these people have been there they havent got a clue 🙄
This is information that a majority of physicians don't know anything about.
But will gladly prescribe you a SSRI
You just watch a UA-cam video and believe everything you hear. LMAO.
@@laurav.7241 nope. Been on SSRIs for decades from many physicians and did my homework. Plus you know... Experience
Nobody told me long term use of anti-depressants can deplete the body of vitamins and possibly lead to thyroid disruption. After I was diagnosed with low thyroid, I was told I should have been taking a daily vitamin B.
everyone should take it imo.
Well Holly, maybe the doctor thought it would be obvious. Or maybe they just don't have time. It is annoying I know. But every medication has a side effect. Antibiotics really mess up and destroy healthy gut flora, which can lead to a whole host of other health issues. People should be taking B vitamins regardless of whether they had a course of antidepressants. If not done so already, I suggest you get a full blood test check what other deficiencies you may now have.
I take so many vitamins a day. I figure I’m covered.
thanks for that now i now why i have had to be on complan for years after nearly a decade on ssri's.
@@1978UA taking too many vitamins and minerals can also be bad for you.
I've been taking Escitalopram since like 2017 and I am excited to find out what I have done wrong that I wasn't told about for the last four, going into five, years. That said, they have helped me a lot with regulating my mood issues and depression so even if I have made mistakes, they still have helped me.
Yeah I just found this video today and I'm kind of annoyed cuz I just got on another medication! Because I felt that the Lexapro wasn't working 😡 I swear everyone in positions of authority leaves out information
@@Yeah_You_Thoughtdear did u feel pssd ?
I had the worst side effects from this medication. I didn't even get to the full dose yet when i felt like i was gonna die. I literally got half of the side effects from the side effect list that comes with this medication. And getting back to normal took me a year. 10 days destroyed me, and a year to recover. My gynecologist was pissed that this medication is still prescribed coz of the side effects that it has on the mammary glands (that it just one of the many side effects i got). She said that she sees these side effects too often....
@@SpiritDragoness Oh dang, that is awful! I am thankful I didn't have bad side effects when I started taking them. I had a lot of worry about what if the meds were placebos and would I ever be able to stop taking them. I am over that now, but the worry and paranoia may have been a side effect
@@Yeah_You_Thought Or you may not have had a competent doctor.
Having been an RN who trained at a teaching hospital for the local University, I am always wary of doctors who do not know enough and do not keep up on the most recent medical information.
Sometimes, you can do your own research, or switch doctors.
I never knew that about NSAIDs. I knew about MAOs, St. John's, did not know about 5HTP.
I'm surprised at how little of this was actually shared with me over the years, except for interactions with other SSRIs, because of needing to tweak meds in the past.
Thank you so much for this video.
Micro doses about 100 mg of magic mushrooms also good for depression, or so I have read, and it also helps make new Neuro connections in the brain. But I don’t know if I can take them with my Ssri’s.
Some side effects can occur because of a reaction between 2 medications. I went for 2 months before it was discovered that the mix of one specific SSRI and another med I was on brought my blood pressure below normal levels.
Neither of them had that listed as a side effect. So if that happens, notify your Dr. and see if that could be the case.
It was not even caught by the pharmacist.
I was on an MAO inhibitor ( Nardil ) for Post Partum Psychosis. SSRI’s did not yet exist.
Nardil is a very scary drug, but I had no choice.
@@1978UA I have heard about similar studies and I appreciate that you're spreading the word about psilocybin therapy, but it is still a very relatively new science and I don't think science has had a chance to legally make these experiments accessible to alot of people that may/might not find alot of either pros or cons to that level of therapy yet. I like the prospects of the studies becoming more widely spread out, but there is still so much negative stigma surrounding the treatment because of the culture it represents. And as somebody that took mushrooms recreationally over the years, I'll admit that it's the culture that is often romanticized by the rec users that has made our science teams/government legislation boards full of doubt about the positive medical aspects and perhaps not taken these studies seriously yet. Idk, but I support the progression of that treatment the more we find out about it as limited as the clinical trials seem to have been in recent years.
@@pjsmith4369 sir i am taking MAO inhibitor and i want to know mao is best or ssri ppz guide me i m suffering from depression last 7 years
Escalitopram has improved my life massively. Thank you for your very clear well explained video.
I been taking Sertraline and Bupropion for yrs. It's helped immensely with depression.
@Touko Fukawa Talk to your prescriber about it! There's lot of medications out there, it could be you just need to be on a different one, or perhaps on a different dosage.
But it IS a common issue with anti-depressants where it sort of... sucks things out of you? I guess? I'm not an emotionless robot, but it's harder for me to want to do something creative since I've been on sertraline. I mean I love not feeling like I want to kill myself constantly anymore, but I miss the days when I felt like drawing as well.
But anyway like I said, make sure your doctor knows how you feel! You can discuss other options with them, whether it's just going with a smaller dosage or switching to a different med altogether.
me too, it’s a great combo, although if I go a day or two without taking one of them while still taking the other I get extremely irritable and angry
I've been taking Celexa for over 20 years, 10mg/day for the first dozen or so and 20mg/day for nearly ten. Two years into initial treatment I read an article on SSRIs that listed a side effect of some as reducing migraine incidents. I'd suffered from migraines for over 40 years, never going a week or a month without one or occurring several days in a row at the same time of day or night. I realized I hadn't had one since taking the meds, and at 71 I still haven't.
Welcome to the club mate, Ive been on Paxil 27yrs
I too suffer from migraines. I think my partner was on Celexa but he had some other side effects from it.
Yay!
I've had occasional migraines since I was in my early 40s but so far not one since on a ssri
John, have you ever heard of 'poop out' i.e. the idea that for some people it suddenly stops working (Paxil/Paroxetine) after many years, I suppose this can happen with other SSRI's, I sometimes worry about that and so tapered to a low dose of only 5mg but life is tough on 5mg, I tried 2,5mg and all manner of demons raise their ugly heads, depression, anger, sadness, worry, stress etc etc, this is my sticking point he 2.5mg stage.
Im 55yrs so started taking it around 28yrs of age and was on 20mg as well initially, the last 7yrs tapered down to 5mg from 15mg (at some point I dropped 5mg)
Ive read that the amount of serotonin circulating around in the brain lessens over the yrs of taking SSRI's, so Im not sure what this means the lessening of this pool of serotonin, does it then dry up eventually?
The reason poop out is frightening is that 1. Depression will return with a vengeance and 2. Withdrawal or discontinuation syndrome sets in, wow - those 2 would knock anybody out. So I keep my drop to a minimum, but at times do wonder and think Id be happier on 10mg or even 7.5mg.
I ended up getting a rare side effect of sertraline: significant worsening of short term memory. It got to the point where, within the 5 months I took it for, I can only remember very few bits and pieces of the last 4 months before switching; everything is basically blank for me for the last 3 months, save a few horrible moments of emotional despair. Now I'm on escitalopram, with no signs of those side effects thank god.
Bro wtf this is exactly like me as well,should I let my doctor know about this???
@@rxndzvi yes, absolutely!! if it's impacting your day-to-day life negatively, that is NOT normal. Everyone's brain works differently, so if one medication isn't working for you, then there are many, many more to choose from. Keep your doctor in the loop!
@@adhdhikaru ok thanks for getting back to me appreciate it i will let my doctor know👍
@@rxndzvi good luck my guy 👌
I've been off of it for over a year and still have a horrible memory
I had serotonin syndrome for months because I'm a fast metabolizer and it was awful, but I didn't even know it was happening because I was never told any possible symptoms, thank you for this video
What did Serotonin syndrome feel like
@@luxlifewithmeg2552 also interested, and what did he do to reach that spot, just the ssri or did he mix something
What did it feel like and why did it happen, did you mix something with your ssri
@Gretchen K. Adding to this: uncontrollable vomiting, sweating, shivering, dissociation, hallucinations. The few times it happened to me (caused by taking cough medicine) I remember being certain that this was how I was going to die. If my roommates hadn't been around to take me to the ER I probably would have.
No one told me what it's like, and this video said NOTHING about it...just what to avoid to avoid it...big help...not..
I was prescribed Mirtazapine for insomnia about 2 1/2 weeks ago. One of the big side effects for me was the elevated edginess and anxiety it created. It's done a great job at fixing my sleep nonetheless. But as soon as my doctor heard me mention the side effects she quickly prescribed Fluoxetine. Never ever been on it. And after watching this and all the things to avoid I think I further want to stay away from it and just wait for these side effects to wear off. Personally I think sometimes these doctor rush to fix every little problem with a pill and expensive follow up calls and visits. We forget there in a business to push things that may not always be the right thing for us at that time.
thank you so much. nobody ever told me about these. I've been on antidepressants since 15 and I've always taken ibuprofen, and wondered why i would feel worse. so glad i saw this video.
I want to share my story so that others do not make mistakes. I suffered from serotonin syndrome after two weeks of taking Prozac, and then the doctor added another medication for me, which I took, and I had a panic attack, severe fear, and confusion, and I felt like I was going to die. I went to the emergency room in the hospital and met with another psychiatrist who had no experience. I told him, unfortunately, he said: I have anxiety that is not from the medicine. He gave me another medicine, so I believed what he said and I went into a coma due to serotonin poisoning. The medicine was withdrawn from my body, but I suffered from severe depression and anxiety after that because of this incident. I continued to suffer for years, and I am now fine, much better than before, and I am still recovering without any medications. An antidepressant. When I went to a psychiatrist, he went because I had a phobia of giving lectures at university only. I am very regretful and wrong for going to a psychiatrist. I lost 3 years of my life because of that.
No I agree, none of the doctors I’ve seen in the last 20 years and have prescribed most of these over the years, have never ever said a thing!! I’m
Shocked!,!
I was only on fluxotine for a matter of 2 weeks, it made my migraines worse, I felt more depressed and anxious. I stopped immediately. I'm now waiting to be seen by a psychiatrist to see what therapy is best for me.
Maybe your dose was too high
They(drs) like to tell you to persevere for at least 8weeks on new meds, but would they if if made them feel so much worse??
@@diplomasaurus4232 Because "feeling worse" is only temporary and the benefits are worth waiting for. The doctors should really state that the medication will make you feel worse initially though so it does not come as such a shock to the system.
I also had horrible migraines for the first couple of weeks, but on sertraline, and that seems to be quite common, especially if you’re already prone to headaches and migraines. But I’ve had that with every single SSRI that I’ve tried, and the side effect does go away for me after the third week. I really hope you can find something that works for you 💕
Fluoxetine takes longer than other SSRIs to start working - 6wks as opposed to 3-4. Feeling worse for 1-2 weeks (not 6-8!) is to be expected and they should inform ppl of that, but you shouldn't 'tough it out' if it's making you massively depressed or suicidal, and worsening migraines is probably a deal breaker for many :/ But it's quite possible a different SSRI would affect you differently, it's weird how different each can be for different people. (e.g. for me personally, fluoxetine is the only one that doesn't make me sleepy, oddly since that not very common for SSRIs, and lexapro/escitalopram was the only one I couldn't drink on.)
Wishing you lots of luck, it's great that you're gonna see a psychiatrist!
I would love to see you do a video like this on ADHD stimulant medication!
I recently started on an SSRI, and this was extremely helpful! Thank you! 👍
I was put on anti depression pills when my son became ill, I was not depressed!!!!! But because I didn’t know where to turn I took them…. When he passed the doctor increased my dose and I was left to it…. No longer on them and so glad ….
Could I ask what your dosage was and how did you manage to come off that dose, who oversaw you coming off them and how long did it talk? I take 200 mg per day. I would be most grateful for any advice.
@@chintzyhall8731 I was on 150mg and reduced the dosage myself. Not really recommended to do without your gp’s say so but, I reduced slowly until I eventually stopped taking them. Side effects of the reduction were like fireworks going off in my head and was quite distressing at times. Guess the right thing is to ask your gp if you want to reduce them and be guided by their advice. Good luck
@@Andy-cb4uv Thank you for taking the time to reply. I know exactly what you mean by "fireworks" - I'll have a word Wirth my GP.
I take sertraline and buspirone, and I discovered on my 21st birthday that they do NOT go well with alcohol. I was shaking the entire night.
I know someone who was on venflalaxin and just switched to fluoxetine. This will help me help her during the transition. Knowing what food and over the counter medication to avoid is pretty important.
I’ve been on Zoloft for a few years now and I’m so happy with it. I’ve noticed that I can no longer take melatonin though. It makes me feel very jumpy and anxious.
Got on Zoloft/Sertraline a few months ago, probs just before Christmas. Absolutely changed me and I'm endlessly happy for it
@Drew Jackson Before that, a year or two prior I tried venlafaxine. I absolutely hated it: nasty bouts of insomnia, hallucinations, mouth so dry I could choke! Horrid brain zaps too. The comparison to my experience with Zoloft is like night and day, with the Zoloft I experienced some bad nausea and felt a bit uppity, but the change occurred within a week and the biggest thing is my mood has entirely stabilised. I initially went on it for anxiety reasons, so I'm not sure if that's why one didn't work, but my doctor did mention I had depressive issues as well. I don't want to off myself every day at least now, lol. I'm a far more pleasant person to be around: I'm not angry all the time, I don't snap at people, I'm way more inclined to show concern at friends being rude or off to me rather than lashing out and becoming vindictive. I feel like I have the potential to become a good person now. Nothing like that happened with the venlafaxine, I just became ten times more anxious and felt absolutely dreadful.
me too! for the longest time i was ashamed and very hesitant to take medicine. but once i started, it is like night and day in my general mood and ability to just complete everyday tasks. i am endlessly grateful for it. plus with the sertraline i have not experienced really any “negative” symptoms except a very occasional nausea.
@@jess57565 Basically the same for me. I have occasional nausea now, particularly with certain foods (particularly creamy, garlicky and mildly spice- used to be the worst for spice but I love it so much I soldiered my way through it) but it's 100x worth it!
I just started Zoloft yesterday, it’s my first time taking this type of medicine so I’m nervous but so glad I finally got onto something
My mum was prescribed mementine for Alzheimer’s disease and also sertraline, whilst she was in a care home. The ‘memory clinic’ kept increasing the dose she was on. From 25mg to 150mg. My mums muscles started to stiffen and we were told that sertraline and mementine shouldn’t be taken together.
Horrid stuff sertaline
They should of never given your mum this drug it effects cognitive disorder badly.
If you think that the nurses in a nursing home understand medication interactions, I have a bridge to sell you. They aren't sitting there at the desk reading the latest nursing journals. They almost always have a h.s. education and couldn't wade past the index page.
So glad im off these meds now, been a couple of years since i had my last dose... there is hope for us all if i can get off these drugs then we all can.
That’s great for your journey, but these are life saving drugs for a lot of people and coming off them may not be the right goal for them.
Can't wait to try ssri's
These are not recreational drugs for the most part.. Some people do need them to get on with their lives
How long were you on them for? And what med did you take? Thank you.
Those meds are dangerous
I abruptly discontinued cipralex and i thought I was fine and then approximately a month later, I woke up and was extremely suicidal. Out of nowhere!
I am on Prozac *for many years* and eat grapefruit occasionally. I have never noticed any increase in side effects. That being said, I only eat a 1/2 at a time. It's probably not enough to make a difference.
There’s a lot of reasons why Im on SSRIs I blame school bullies and being picked on for a lot of it I think it comes out in you in later life sadly x
I think they do but I’ve found Prozac to be most effective than any of them sertraline made me like a zombie and venlaflaxine is just horrendous xx
I’ve not been too happy with the weight gain side it piles weight on you like nothing xx
@@orangesnowflake3769 I know mood wise I think I’m pretty much the same person I was 20 odd years ago not much difference there x
The bullies are evil and should’ve been aborted as babies.
Never go on fluoxetine it's bad . thankfully they stopped working on me but made me ill alot.
the esclipram has been great, except the 80lb weight gain, gas, etc. Since taking this my appetite has increased so much it is crazy difficult to resist... But seriously the anxiety is gone it does work. Im working on loosing the weight
Hey there! Can u please answer when did u start feeling better? Im on day 22 now, not feeling much difference yet. I have anxiety and depression
There are other meds that don't have this effect.
I never knew this. Ty.
i think it would be good to address that a lot of antidepressants can interact with marijuana and cause serotonin syndrome. because marijuana, especially when smoking it can encourage reuptake of serotonin. it only really happened to me twice both times i had smoked it and had consumed a decent amount. i can consume edibles just fine though so do what you will with that info
Thank you for this! Happened to my sister, triggered her bipolar disorder and honestly, it just isn't talked about enough
@@Purple_kiwi_ you're welcome i get mild serotonin syndrome but it can be dangerous if it gets to a more severe level. marijuana definitely has adverse side effects for some but obviously when used properly and safely and in ways that work for the person it can be great.
People also don’t realize that Marijuana itself is a stimulant, and can cause issues with other stimulants such as ADHD medication (Amphetamines). Can give you high blood pressure etc.
@@SleepySelkie96 omg i didnt know that, recently started taking methylphenidate and started on sertraline this week, i smoke a small spliff a day, i guess i should consider stopping then :(
@@nenee009 If you’re only smoking small amounts, you may be able to continue use. You just need to monitor your blood pressure since, adhd meds can cause higher blood pressure themselves. I’d talk to your doctor about it!
oh cool I've been eating ibuprofen like mad since December because of dental problems while on escitalopram. If you don't look it up yourself nobody tells you these things :(
Man, you're on a roll with these videos! Just in time to review these concepts for my exam. Thanks, JJ Medicine!
Good luck on your exam!
I’ve benefited so much from mine but jeez, the sexual side effects are killing my relationship! I’m trying so many different things to get back to the love bug I was before.
Go see a specialist. There is a cream that women can use I think it’s applied under the arm or on the flank that helps even out hormone levels. I’ve always been a very sexual person and my wife doesn’t have quite the same drive. It’s been a bit of a struggle but recently a lesbian woman I know told me about this. Ssri’s are powerful drugs and can have many negative side effects too. Over the years I stay faithful through communication and a lot of masturbation but now I’m hopeful she will see a change back to our earlier years. Hopefully that’s not TMI lol.
@@lh98 not tmi. It’s reality. But my psych and I are working on it. Lowering my dose and adding a supplement that’s supposed to help with depression the same way SSRI’s do. We are trying that before moving on to different meds. I tried Wellbutrin and had a horrible reaction.
@@lindsaycrystalhealing6063 Don't give up.
For me, it hasn’t affected my sex drive but has caused delayed ejaculation, which can be helpful…or not. For women I’ve heard that some ADs are designed specifically to address your concerns. Good luck!
@@BenSussmanpro yes! My partner had the same issue with the first couple meds he tried but luckily got it worked out. My dr immediately thought of Wellbutrin since it has no sexual side effects but unfortunately it sent me into a really deep depression and I had to stop taking it. What meds do you know of that I could try? I’ll bring them up to her. I have major depression, anxiety and ptsd. I’m on separate anxiety meds currently so I mainly need something to keep my depression in check. Of course I’m also in weekly therapy so I don’t rely on meds alone.
I have never had a patient have issues with SSRIs and NSAIDs, except one young lady who started having intermenstrual spotting when we started and SSRI for depression (she was using motrin prn for menstrual cramps.) Very interesting stuff! And great video, thank you!
not true movement disorders i got meige and blephorspasm from antidepressants made my life a living hell i been taking magnesium which has helped and i had to stop the dangerous meds so i can function i took alpha lipoic acid started 2 years ago for nerve pain to my supise they help alot more for my depresion then a few antidepressants i was on
She had the bleeding issues before or after starting the SSRI? Is it okay to take nsaids for cycles while taking SSRI
You are absolutely lying. SSRI can cause pssd
I started out on Buspar then wellbutrin and finally in 2011 Quetiapine the latter was a life saver, I'm still taking it. Thankfully I haven't needed any of the other medications you pointed out. The video was very informative!
This is a great style of video. Informative, gets right into it, and covers a broad range. Thanks!
I love that you mentioned grapefruit. It actually slows down CYP450 too, which, from what I'm understanding, is a family (I think the cytochrome you mentioned may be in that family) of enzymes that metabolizes most antidepressants, anxiety medicine, and painkillers. None of those things will work on me unless I eat grapefruit, I had to figure that out on my own too after essentially experimenting on myself. 🙄 I ate half a grapefruit every other day and after 2 weeks I only needed a fourth of what I was originally taking. I went from still having panic attacks while on 2mg of Xanax (plus several other sedatives and medications) to only needing .5mg and I am now able to just use Kratom powder to prevent most panic attacks from happening. Grapefruit isn't super reliable though so I have a lot of trouble any time I'm needing painkillers. It's the worst at the dentist because they never believe me at first so they take forever and stab me so many times trying to numb me until they finally use a painkiller that is metabolized differently. 😑 All the painkillers that they've given me to take at home still won't work unless I take another 1,000mg of aspirin or acetaminophen too. I wish there was a cure for this kind of metabolism issue. Another person in my family has it too and it's just hell on us both. I believe something should be able to be developed from grapefruit to help people like us but it seems like it's a highly overlooked issue.
Also, before anyone assumes I just built up a tolerance from recreational drug use or something. No, I have never used recreational drugs and I've been this way for my entire life. My son may also be that way considering ibuprofen won't even lower a fever when he's sick. It's an issue that a lot of people who carry the red hair genetic have apparently.
They won’t investigate and provide a natural cure because they’re too busy farming out their dangerous preparations.. Grapefruit could be the answer to a bucketful of problems.. I don’t trust the pharmaceutical companies at all.. take care out there, love from England..🌎 P.S. what is Kratom powder..? Thank you 😊
By any chance, are you naturally red-headed?
@@Fuzzysea693 I was born with strawberry blonde hair, so I do have the red hair gene. I have heard about the link between it and the issue with metabolizing these things too quickly.
I just wish they would work on finding a treatment or cure for it. I don't think the scientists realize how serious it is. 🤦🏼♀️
Psilocybin containing mushrooms saved my life. The drastically reduced my benzodiazepine withdrawal allowing me to quite illicit pill addiction after three years of heavy daily use before it would had became medically dangerous to quit. It has also helped me survive depression.
@Lillian Victoria I was having this constant, unbearable anxiety due to work stress. Not until I came across *dr.jeromespore* a very intelligent mycologist. He saved my life honestly
You can check him on 👇🏻
*l* *G*
@Vicky Desmond I feel the same way too. I put too much on my plate and it definitely affects my stress and anxiety levels. I am also glad to be a part of this community.
@@ellaaysun6181 It’s quite fascinating. Is this person reliable? I’m eager to get some GT
drinking alcohol on fluoxetine almost got me hospitalized twice. drinking alcohol on escitalopram is perfectly fine for me and i can drink as much as i could without meds. fluoxetine had a shitton of side effects for me, escitalopram has none. for fluoxetine, i could only take the lowest dose (5mg) and for escitalopram i'm on the hightest dose (20mg) with no side effects. i love escitalopram. maybe you can tell.
ive been taking fluoxetine since december 2020 and i did not know i was not supposed to drink alcohol and it also made me lose control so much faster and not in a good way. It also fucked up my moods and did not help me
@@tessthemess410 i too have made only bad experiences with fluoxetine :/ hope you find something that works better for you!
I got lucky and I only have one negative side effect from Fluoxetine. Dry mouth. Brains are whacky, and SSRIs are relatively new. The workings of the human mind are still being evaluated by medicine.
Don't be afraid to tell your doctor that an antidepressant isn't working for you. Every individual is different, and having so many alternatives means doctors can try out different ones and figure out your best option.
I can drink very heavily on Fluoxetine - and I'm on a high dosage - and be completely fine. It's so weird. I've been very lucky. Alcohol does make me dizzy quicker if other stuff is involved. Like at gigs, when I drink and I'm jumping around and yelling. I nearly pass out but sat and drinking, I can drink loads and be fine. I think I've personally been really lucky with Fluoxetine. It's really really helped and caused near to no side affects. I know you're not sht talking Fluoxetine but when people tell people not to take it, that makes me really angry. Yes it works for some and not others but you just keep in close communication with your doctors and tell them immediately if you have problems.
I don't usually drink often anymore, maybe one night every month or two, however I've noticed on sertraline I am utterly bladdered after 2 or 3 drinks :s I'm usually a "lightweight" but now I physically cannot binge drink on a night out or "keep up" like I used to, probably a good thing tbh but I wonder whats going on there.
man ive been on paroxetine for about 10 years now and was never talked to about which foods/drinks to avoid- i guess its a good thing i never liked grapefruit 😂 thank you for this video! its absolutely wild how much we know about brain and body chemicals now; wild but wonderful
This is the first time I've heard of all of this. I've been using Fluoxatine for nearly 20 years.
Is paroxetine working for you?
I've tried Fluoxitine, Sertraline, Escitalopram, Duloxetine, Venlafaxine, and Buspirone. None of them worked for me unfortunately. I just started Vortioxitine and Abilify. I'm really hoping they work. After trying the first 6 meds I tried to go unmedicated and my depression got more severe mostly due to life circumstances but I realized I need medication. This was a great video, thank you!
I had treatment resistant depression so I also tried several until I was prescribed ablify with it. Turns out I have bipolar and since treating that it’s helped so much
Try Paxil
No one told me that I should be careful taking ibuprofen with sertraline. 6 months ago I had a hip replacement at the age of 58. I had been taking sertraline for 8 months and ibuprofen for about 12 months due to hip pain. Before my hip replacement I wasn't told to stop either of them and after my hip surgery I needed a blood transfusion because during the surgery I had lost so much blood. 🙄
yikes - the drug interaction databases are a must visit.
You should have been told to stop certain medications during your pre-op office visit. Most if not all surgical offices give you literature on what medications to stop taking.
@@jeanettepaynter1183 I should have been told but I wasn't 🙄. No mention of either medication in the folder . They did tell me to stop other meds but not those 2.
What's crazy is that nobody told you to not take an NSAID daily for months! That's absolutely not safe, and yes they def should've informed you to quit before the surgery, so sorry that happened to you. Acetaminophen is the only OTC pain med you can take longterm (as long as you don't exceed 6-8/24 hrs and your liver is ok.)
@@Suzanne4415 it was fine to take ibuprofen long term as long as you take no more than 2 three times a day. My GP told me to take them with cocodomol. I couldn't walk without them before my hip replacement. 🙄 .
I don’t miss alcohol since there’s plenty of non-alcoholic beverages to enjoy. But DAMN… I miss having grapefruit!!! 😢
It’s worth it though to be able to function without having a meltdown every day.
I was doing good until the ciprofloxacin lol. I take cip for regular UTI's. Good to know this though. Also when my doctor was doing research for the right anti depressant for me as I'm a fair amount of medications. He mentioned that when taking sertraline with tramadol it can also lower the blood pressure.
isnt that zoloft?
@@janehyden1652 I just googled it and yeah Sertraline is also known as Zoloft. Zoloft is its brand name.
In case you have had any seizures, tramadol lowers your seizure threshold. Just in case, because I do.
If you have frequent UTI's and you are postmenopausal, you would probably benefit from a vaginal estrogen cream. It will stop your UTI's.
Cipro is poison be careful
I was seeing a doctor while trying a new SSRI (I think it was citalopram) and he prescribed me Sumatriptan for my migraines. I was in the office while he said he was going to prescribe it and I went "wait, isn't that dangerous? Both medications have huge warnings of not to mix." He said it'd be fine and not that big of a deal. I never went to that doctor again, and didn't really need an antidepressant at that time. Even the pharmacist was like WTF, no.
I was prescribed Sumatriptan while on Escitalopram once too. I had no idea they shouldn’t be taken together and was never warned about it. Luckily for me, I did find out that you shouldn’t take the former if you have epilepsy (which I do.) so I never did. For some reason the information about me having epilepsy wasn’t marked down in my record @_@
Having been on SSRIs for years, & having way too many migraines, I did not find my use of Imitrex to be a problem.
I'm increasingly a big fan of running new meds past the nearest pharmacist as they're super knowledgeable about interactions. Glad you knew to ask about that particular combo!
My nurse prescribed me lexapro after tapering off zoloft but didn't say anything about waiting any time between medications. My pharmacist said I couldn't take them within 5 to 7 days of each other. He wouldn't even let me have them because he wanted me to be safe. My nurse didn't tell me any of that. Just added to the list of reasons I need to find a new place and a real doctor. Thank God for pharmacists!
Suma and escitalopram have been fine for me so far.
this all makes so much sense. i was on zoloft (setraline) from 8th grade - summer of junior year. they moved me from 25mg-100mg over a few months and i was acting out so bad. had no idea why but i was all wacked out. i was starting to drink and obviously was on antibiotics when i was sick and would have such weird reactions. same with advil. my junior year summer my moms insurance was dropped and i had no access to meds. all of 12th grade i went cold turkey and not having a great year. had brain zaps for a year after that. i was acting reckless and doing anything without serious thought and gave no sh!ts and was seriously unhinged. i would cry and freak out and be so angry my skin would crawl with disgust at literally everything. had so many fights with my family and boyfriend like damn i was so mentally unstable from setraline's side effects. i had absolutely no idea until now and just thought i was crazy.
dose was too high , for me over 100mg is too much but 25-100mg is great. ive accidentally taken the meds twice (by mistake) & it felt very horrible
Jada, I truly hope you’re doing better. What a horrible thing to have to go through, especially as a teenager! My 14-year-old daughter went through hell the past 18 months. They tried out several different antidepressants, then finally she got on Zoloft and it’s really helped her out a lot. 🙏🏼
@@polytheneprentiss1534 hopefully the doctor doesn’t prescribe too much....
That’s so awful for a teenager to have to go through med withdrawals because of insurance! I’m so sorry that happened to you, and I hope you’re doing well 😔💖
Girl just smoke a lil weed
Btw, when a physician prescribes medications they know the risks and interactions between all meds that they are prescribing. So they weight the pros and cons to each med. They make an informed decision and weigh the risks. So most time you are taking meds that interact with one another but not to a significant degree that will affect you. That’s why people don’t die left and right every day.
This. There’s no harm in asking to make sure your doctor is aware you’re on everything and has considered it, but things *can* be used together safely if done with an awareness of dosage and side effects and so on. I’m on an SSRI for PTSD and I take Tramadol for autoimmune arthritis pain management and I have done for years.
while this IS true - they are still human. I had an incident with a new medication that the *pharmacy* staff picked up on that shouldn't have been prescribed with other medication I was already on. my doctor did NOT pick up on this.
@@juliaconnell To be fair that is exactly what pharmacists are for.
ETA: she is right that *physicians* will not always be 100% on top of all interactions & their respective risks, as stated in the comment she replied to. Didn't mean to be dismissive of the fact that they messed up hers & she suffered for it. (But they still are a lot more so than many people think after watching this.)
well, they should know. Unfortunately, the ones where I am have pretty consistently prescribed medications that are not meant to ever be used together, including giving someone a MAOI right after a SNRI, in the same day...
(which should NEVER be mixed and this patient did not make it)
While I agree, most doctors know what they are doing, it's still good to be careful and double check with your pharmacist if you have any questions as well.
@@meztlistormheart2636 i was giving the reason why they don’t tell patient all of this. And again I will mention. You weight the risks and benefits. And if the benefits outweigh the risks, it will happen.
Thank you for this. I had no idea that antibiotics could affect my fluoxetine that I've been on for years.
You're welcome. Only certain antibiotics can lead to increases in serotonin (especially Linezolid and to a lesser extent ciprofloxacin).
Damn i didn't even know Cipro can interact with SSRIs. I'm on zoloft, quetiapine, mirtazapine and lamotrigine. Used cipro for about 3 weeks along with other antibiotics. I guess i'm lucky i didn't develop SS
@@jjmedicine Let’s imagine “a friend of mine” having taken Paxil for 17 years. He quit alcohol in 2009, nicotine in 2011, just finished tapering off of Klonopin, after 31 years, and is considering a slow taper off of Paxil.
There’s no intention by him to ever cease lithium or bupropion. He’ll be discussing this idea with his doctor during his next appointment, in a couple of weeks. He’s 50+ and recently began studying Paxil and learned something he never expected: that it’s notoriously hard to quit.
It’s my understanding that he’s pretty nervous. Is there anything more he might learn?
Am enjoying these videos as they are clear & your use of the screen with bullets in your outline form are visually helpful.
One suggestion: the use of the yellow heading was very difficult to read against the white background; so the more faint colors are not the best choice, as seen in the topic header: TCA Antidepressants... Thanks!
It’s flat out WRONG to suggest that discontinuation syndrome occurs only when you suddenly discontinue SSRI. I suffered severe discontinuation syndrome DESPITE carefully following my doctor’s instructions when discontinuing Paxil. This situation didn’t simply affect me, so much so in fact that class action lawsuits have successfully proceeded against Glaxo Smith Kline (manufacturers of Paxil) precisely because of this and other problems with this medication. You should have been more clear that no matter how gradually you decrease this medication, you may STILL suffer discontinuation syndrome. There are people who haven’t been successful in ceasing Paxil, because of this problem.
I started SSRIs recently and had grapefruit 2 days in a row. I feel awfully tired. This video explains that. However it got me to look into the long term affects of SSRI’s which makes me want to wean off them as soon as my 30 tablets are out
Did you end up quitting?
You must...
@@lisaalexander1824 what are the affects of long term use? Been on Zoloft for 6 months
Update?
Get off them and instead take psilocybin (magic mushrooms). It has helped with my depression and anxiety. No side effects or withdrawals like anti depressants. Trust me
So, when I was on abilify, quetiapine and SSRI I drank 0.5l fresh grapefruit juice while I was waiting in line in a restaurant and I almost fainted. Low blood pressure. Fortunately, I don't take most of it anymore.
Dang, I've been on and off Lexapro for 15 years and not a single doctor ever told me to avoid anything.
I use to be on Zoloft. I was still depressed and I constantly got high fevers. All I was told was don't drink alcohol. I wish they had told me about these other risks. Maybe my regular taking of NSAIDS, Antibiotics, and Anti-emetics caused the fevers, anger, and stomach pains I had on Zoloft. I wish doctors would just be honest I've had so many tell me drugs are all no risk, you can mix anything, classifying addictivedrugs as non addictive.
they only say dont drink to cover their own asses
Boost your health literacy. You have to do the research for yourself. Not doing so could send you to the ER.
@@Cathy-xi8cb You are absolutely right. I know that now. Unfortunately sometimes you can't just trust anyone because they are supposed to be a professional.
@@jazzmyne6881 I am a licensed medical professional, and I can tell you that no prescriber has the time to review everything with you anymore. No one was being "dishonest" with with you, because they are thinking only of warning you of deadly reactions, not the ones that make you miserable. Most prescribers also specialize, meaning that they cannot possibly stay current in every area of advancement outside their specialty. Pharmacists might guide you, but not after COVID turned them into vaccinators in their "spare time". The only answer is to look up every medication, every condition, and start to learn as much about things as you can, every time, every situation. And try hard to stay off all medications if there is another effective way to address your condition(s). As providers, I can assure you that this is what we do for ourselves and our families. We aren't fond of drugs because we know so much about the complexities. We will take them very mindfully when the alternative is more illness, injury, or death.
@@Cathy-xi8cb Yup you're certainly right about all of this information and the advice is very helpful Thank you : )
Stopping Paroxetine was awful (took 3 months).
Rapid increases in dose may cause Serotonin Syndrome but this risk is normally pretty small. You are more likely to suffer other side affects like headaches, nausea. Fever is a concern.
Grapefruit interacts with a ton of medications. Most antidepressants have very little interplay with it. The mentioned CYP3A4 Enzyme is actually a whole family of enzymes. Unless you have a bad gene for the right version of an enzyme to metabolize your drug it is unlikely to affect you. Genetic testing is available affordably for this type of interaction.
St. Johns Wort is a serious risk. There may be a genetic component but it is very common in serotonin syndrome cases.
5-HTP is a serotonin precursor. It doesn't tend to interact unless people have rarer genetic conditions or are on TCAs/MAOIs. Most Tryptophan gets destroyed in the stomache. It is not stable in Acids. Bio-availability is normally 40% or worse.
Lots of medications interact with the CYP enzymes. Expect your pharmacist to notice as their software and training is to look for this; your doctor likely will not. This is why it is important to try to use the same pharmacy.
It is really bad to mix different types of anti-depressants without supervision. I currently use two. I am fine. But there is a real reason to be concerned otherwise. The TCAs and MAOIs are especially dangerous.
What are your credentials (not challenging, I just spend a lot of time on random science videos like this one and I like reading the comments. Sometimes you come across R&D scientists for pharma companies, sometimes you come across the PhD who helped characterize an enzyme. You just seem to know good stuff)
@@reikiessence11 Ive been on it 27yrs, yes its a bitch to come off, the withdrawal or discontinuation syndrome pulls me back
You are lucky you could get off, it seems to me that the longer you are on it the harder it is to come off, its like it becomes a part of your brain and trying to stop it is like literally taking a chunk of your brain away, the brain will rebel and do anything to get it back.
your comment was more accurate than the video itself
I'm trying to get of it after 25 years and I feel as if I'm going insane.
Great info. Doctors need to recommend your video's when they put you on an SSRI. I found out the hard way! :(
right ? Especially with common things like grapefruit and Advil !!
I asked basic questions that I thought were important like "can I drive?" "are they addictive?" etc
Never thought about grapefruit or any kind of straight forward staple that one could accidentally consume without knowing it could cause problems.
These seem to be prescribed very readily in the UK to anyone who says they feel anxious. Kinda glad in a way as I would never have pursued it if it was going to be a whole consultation before I could get them. They've helped massively.
@@dogpawz Grapefruit is banned for many drugs including Lipitor.
Wow. I have fibromyalgia and also take Sertraline for depression - and I’m on several other medications that all increase risk is serotonin syndrome- now I just need to find myself the will to not convince myself I’m at deaths door 😂😂
How were you diagnosed with fibro and what were your symptoms? I heard it's very hard to diagnose.
@@Haddy26 hey - it’s the kind of rule everything else out type illness, I was referred to a rheumatologist who did several tests and came up with the diagnosis
@@sleeplessinscotland2578 I've been having severe fatigue, no energy and muscle aches for the past week, and it's happened off and on a month ago as well. I figured it's just a side effect of my depression and anxiety but I'm wondering if it's something more.
As an advil taker with severe anxiety I'm waiting on this ad to end so I can have a nervous breakdown learning about why I can't take advil with my sertraline. Idk why I do this to myself 😭
Been on fluoxetine (40 mg) since I was 16, 32 now but I’ve been fatigued my whole life due to hypermobility syndrome.
Im 17 and on 40mg of floroxitine, is there anything you'd suggest to help avoid that?
@@nola3724 the hypermobility is genetic, I don’t think it has to do anything with the meds. I have always been fatigued. I just didn’t know what caused it because I didn’t get diagnosed with it until I was 30. The doctors just explaind it that it was all in my head because mental issues and I had antidepressives. But maybe it’s good to get to the core issues if you have any other problems involving sleep.
I'm on Peroxetine, I've been on it for years now, and have never been told not to eat certain things, maybe that's why I feel like it's not making difference, I still feel like I'm trying to run in water, lost count of how long I've been on it now but Docs are reluctant to change it.
The docs are reluctant because paroxetine is hell on earth to discontinue.
What she said ^
Paroxetine works. It works very well actually. I’ve been on and off antidepressants since my teen years (I’m now 37). I tried a few and found paroxetine 40 mg works best for me. Through the years I got off to give myself a break and also because of pregnancy. It was prescribed to me for major depression, social anxiety disorder, and PMDD. It did wonders! And still does! But the one and only thing I can say about paroxetine is getting off and going through the withdrawals. They are no bueno. Even tapering down ever so slowly the withdrawals were still there. But just look on the bright side, the symptoms wont last forever although very miserable you will get through it 👍
@@NurseRay Did you need to come off of Paroxetine completely when you were pregnant? Or just lower the dose is okay? I’ve been on Paxil for 5 years and I want to get pregnant in 2-3 years. But I am afraid of coming off. I was on 20mg but not I lowered it to 10mg.
@@valeriemorel3708 oh dear my apologies for the late response! But to answer your question, I DID NOT get off completely. I tapered off kinda fast (which I DO NOT RECOMMEND). When I found out I was pregnant I immediately reduced my original dosage 40 mg down to 20mg. I gave it maybe 5 days then down to 10 mg for another 5 days and then finally down to 5 mg for 5 more days. It’s advised to taper much slower (like for weeks/months. BUT since I actually got pregnant I was not about to put my baby’s health on the line. So yes it was a HARD RIDE DOWN😵💫. The withdrawals were definitely present. For the withdrawals I used Benadryl to ease the discomfort like (brain zaps, fatigue, headaches, just plain yucky feeling). I have used paroxetine since my teen years. I’ve tried to go natural with OTC supplements vitamins, herbs and even therapy. But it has always been Paroxetine that does the job. I also have MS (Multiple Sclerosis) and believe it or not, paroxetine helps with nerve discomfort too. After arrival of my son I tried Cymbalta for one whole year (my neurologist recommended) and it did little to nothing for me. My chronic nerve pain and depression was still very present. I developed PPD (Post Partum Depression) really bad. So I was bumped up to 120 mg of Cymbalta (the highest dosage). It worked for maybe 2 weeks and still I was not myself. So I finally told my Dr that I want to switch back to paroxetine and indeed after about a month (20mg) 2nd month (30mg) and finally the 3rd month (40mg). Right now I can say I’m feeling like my old self again (pre-baby). I’m less anxious, and my depression has vastly improved compared to taking Cymbalta smh. Anyway, I hope what little advice I provided will help you. Just make sure to taper down. It’s brutal but you will get through it! *hugs* ☺️
never knew about the grapefruit thing whilst on SSRIs! I'm on citalopram and works a treat for my PTSD!
Which antibiotics are safe to take with fluoxetine?
My doctor has prescribed me Naproxen long term for arthritic pain and he never once told me it would interact with Escitalopram, which he also prescribed me long term!
My mom has kidney damage from all the meds she's taken over the years. When she went to a kidney specialist, the first thing he said was to stop taking Naproxen. Of all the meds she was on, he said that one was the worst.
@@jazznpercy - I've got RA and recently had a really bad attack my GP gave me Naproxen - I thought I was going to die nearly ripped my digestive tract out
Me too!
3 GP's and 2 pharmacists specifically told me it's safe to take these two together
They should be ok together as long as you are taking gut protection - a PPI or H2 antagonist
Thank you, this is an extremely educational video. Great job!
Thank you so so so much for making these videos. Im subscribing immediately. My most recent diagnosis was functioning neurological disorder as the cherry on on top of my fibromyalgia and list of mental illnesses. I'm used to Avoiding learning about fibro since it takes hints if I hear symptoms I don't have like shaking as i do now, but I'm being heavily encouraged to research FND. I'm very much going to watch closely in case you may cover it as you've covered fibromyalgia and lupus so well. You teach wonderfully. God and 0r whatever power or not bless you. Thank you so much.
Thanks. Could you do a video on Parkinson's and / or Alzheimer's? Thanks.
Yes, I'll be doing lessons on those topics in the near future!
It's like the doctor asked me if I felt any side effects from rizatriptan & escitalopram, but I was like, "yeah probably but anything is better than a full blown migraine."
May I ask you guys a question, here goes > Did you guys start having GERD or acid reflux after taking an SSRI? I started having reflux after a year and was put on a PPI, to stop the acid and been n that since, I think SSRI's have an affect on the LES or sphincter of the stomach or the opening or flap that allows acid to reflux back up into the esophagus thereby, giving the acid reflux sensations.
I did see a study on it, that SSRI's relax the LES, and foods that make you feel relaxed or happy like chocolate or chamomile actually increase Serotonin but also relax this LES as well.
Yes since I started Prozac I’ve been experiencing this and I’ve never had acid reflux before in my life.
Yes! Not on fluoxetine but on sertraline. Never made the connection til you said something.
@@nadyagomolko2149 From what I understand, the SSRI's affect serotonin and thus the sphincter of the stomach relaxes and allows acid to reflux
@@quinn799 Yeah, I only started taking acid reflux meds after a year on Paxil, only recently, a few yrs ago found a study that suggests this, like 25yrs later.
Add valium to the list, paroxetine + valium can just make you unable to breath, and reducing the usage of valium takes very long and is really hard to endure.
They actually use the Grapefruit fact in an episode of Moriarty the Patriot. After hearing that a gardener was being abused by his employer, the Moriarty brothers visit the employer's estate, and notice he has many exotic plants, including a grapefruit tree. They receive an invitation to meet with the employer, and mention that the grapefruit has an excellent taste. He has the servants make juice out of it, he drinks it, and it counters the heart medication he had been taking. No one raises a hand to help him, and he dies. It's episode 2, so you don't have to go far into the series to see it.
SSRI worsens my depression tremendously. Whenever I try to use them, I have SI, life loses all value, I cry with deep desperation, and think about staying under the bed. It's one of the most terrible experiences I always have in my life. The worst of them is Prozac. I keep them very far from me now. Thank God this inferno is reversible. I notice it lower my creativity too. Terrible, just terrible. 😮😮😮
Im using prozac rn and I hate it
I am on Paxil and when I drink, my anxiety the next day is almost unbearable. It’s almost guaranteed that I’ll have a panic attack.
Take THC gummies instead of alcohol.
Screw fluoxetine man, made me so much worse. I take mirtazapine because I also got diagnosed with anxiety that is somehow far more severe! So I'm just glad it works, thank goodness for modern medicine- and I mean modern, mirtazapine is the new kid here.
In the US, Escitalopram is Lexapro, not Cipralex. That's what it's called in the UK. I've been on it for years and have never had any issues with any of the stuff he mentioned.
Oh wow. That’s confusing. Hahaha in Canada it’s cipralex. Weird
n=1 is not science. Just because YOU didn't experience any of this does not mean no one does.
@@HollyOak I don't think she was saying everyone would have the same reaction. Personally, I like hearing different perspectives.
No SSRI is meant to be used for years. You are poisoning your entire body and brain. If you go off you will experience worse withdrawal symptoms than heroin… so slowly decrease the amount you take over a 6 month period.
@@Realalma six months. Wow. That’s too long.
I have been on 5 HTP , melatonin , Gabatropin & GABA and progesterone , estrogene cream and L athyrosene ( dopamine ) for almost 18 years till 8 months ago ….I couldn’t get up anymore …severe panic attacks , social anxiety and definately depression and PTSD …..after thinking that I need thyroid medication my dr said I actually need SSRI & put me on Serdep ( Zoloft ) ….after taking meds for 3 days I was a different person …..I regret have not believed in any meds all these years as I am a “ better “ person now …..working as a clairvoyant medium healer , yoga teacher ….I have compassion for self and others again and don’t suffer these absolute terrible panic attacks and anxieties anymore …..I have never slept a lot as I always was highly strung , highly creative and have had lots of energy ….now I am just a bit more chilled but the extra seratonin has also stopped my hair loss , dry skin , no voice , dizziness , vertigo etc etc …..I will not go off this beautiful blue pill any time soon lol 😉😊😁😂
Holy crap! It's safe to say that just about every substance, RX, food, etc... that one could consume would cause a problem. I think I'll look for natural remedies for my SAD.
I suffer with SAD really badly. What do you take to help?
natural remedies also have interaction issues.
Pot...medicinal ....in my state it's legal I take the tinctures with high CBD and I came off my depressant and anxiety meds altogether...CBD at the very least is also a good option over the counter brand hemp bombs is best...street pot isn't the same as the dispensary stuff no matter what anyone tells u
No, really no. You took the wrong message because you're the wrong audience for this info [ETA: and it's honestly not stated/explained well here]. Grapefruit is a problem with almost any drug, NSAIDs carry some risks for anyone (be extra aware or just stick to acetaminophen/paracetamol). No doc on earth would dream of putting you on an SSRI and an MAOI, or tricyclic. You're not gonna just be randomly downing antipsychotics or lithium one day. And the vast majority of SSRI takers have no (additional) problem w/ drinking.
Basically everything has the possibility of causing interactions, whether you're using prescription meds or natural remedies. I've been on SSRIs for over 8yrs now and I've never had any problems aside from a higher dose causing some brain fog, so I went back down and was fine. I eat grapefruit all the time, take ibuprofen for pain, and drink alcohol and haven't had any problems. Wish he would give some statistics on how rare it is for these interactions to actually happen. Don't rule out prescription medications just because theres a possibility of side effects.
This is a really really good channel!
So much information that isnt commonly known but is very important!
Thankyou for your excellent explanations and descriptions!
Cheers!
One time, about fifteen years ago, my former doctor and also former pharmacy had one heck of a time communicating, and I wasn't as on top of my medications as I am now. I ran out of Celexa, and was out for close to a week. It got to where I was crying uncontrollably and feeling really terrified of my emotional state. I ended up calling the doctor on call to get the stupid script filled.
Never. Ever. Again. It was hell.
Don't do it. Skipping a day by mistake now and then doesn't seem to affect me (this is extremely rare), but there's a reason they say to never just stop taking SSRIs. Maybe this is true for SNRIs as well? I'm not sure.
I'm on two antidepressants, but with doctor supervision, and no ill effects.
You missed out pain flower, many depressed people on SSRI try this for sleep but can give you serotonin shock syndrome and should be avoided completely.
Might as well add on illegal drugs too for others safety. MDMA also increases risk of serotonin syndrome.
methoxetamine as well. Amphetamines, Serotonergic psychedelics
I was on paroxetine for 15 years. For SIX years I struggled with sleeping 12-15 hours a day! I could sleep 7 hours then fall back to sleep for 8 hours more.. The doctors & specialists couldn't figure it out why. I went gluten & dairy free for a year. I underwent many tests & different drugs, which had their own side effects, to figure out why my sleep was so messed up. None of this helped. It was debilitating. Everything around me was falling apart . I couldn't take care of my house or yard. The doctor didn’t taper me off just switched to another drug with the same issues. I also was on nsaids & opiates for severe arthritis. For several weeks after stopping the drug I experienced daily throwing up, diarrhea, brain zaps & daily weepiness. The withdrawl depression was so much worse than the original depression . It's been 10 months since stopping paroxetine and the the weepiness continues. Imagine that your feeling ok and talking to someone about something mundane like the weather and quite suddenly you're fighting off tears & sobbing for no reason. I've become more reclusive as this is very embarrassing. I did find out that paroxetine shouldn't be taken for more than 2 years. I also suffer from migraines & hashimotos. The drug had zero effect on the migraines .There has to be better treatment for depression than these drugs. Medical cannabis has worked better for me. The doctors prescribing these drugs don't really know in depth how to prescribe these drugs or how to discontinue their use. There are some people who have to taper off these meds FOR YEARS! Imagine enduring negative side effects from theses drugs and having to taper off for 3-4 years. If you doubt my experience just check out Facebook pages for support for patients trying to stop taking these drugs.
I can confirm what she said is TRUE. I was on Paxil for 3 years and had withdrawal symptoms for a year and a half. Horrible HORRIBLE side effects and withdrawals. Never again am I going back on anti depressants. I have been taking psilocybin instead and has helped me so much with my severe depression and anxiety. No side effects, withdrawals, or addiction. Best part about it is all natural mushroom. I suggest to start microdosing them. Take them at small amounts at a time because too much will do the opposite and you will have a negative experience.
I've been on Lithium, fluoxetine, and a few other things for years. I was recently told of this negative interaction, and it turns out that there's only a risk if I wasn't taking it regularly. It's interesting the way these things work.
The logic amazes me don't take these things because they make too much serotonin.....but take this pill that makes what little serotonin you do make work longer (less reuptake).
Caffeine, nicotine, added sugar, and dairy. These are the things that'll cause my side effects and drive me into massive paranoia. Thanks for the information. Also there's caffeine in chocolate. The more ya know.
Thanks for sharing. I wanted to mention chocolate has very little caffeine, but you can add cocoa powder to anything. The problem with most chocolate is the amount of sugar it has. The darker the chocolate, the less sugar and dairy, but the more caffeine. Just keep in mind a whole dark chocolate bar has less caffeine than a cup of coffee.
not sure about why dairy'd do that, but the others are well known for causing changes in mental state.
Most of the people watching this aren't neuro scientists. It would be great if you or someone else could explain these medications in a childlike way so that we understand a bit easier.
I understand your concern. I appreciate plain-language presentations.
After a horrible experience at LAX I started experiencing panic attacks daily I finally broke down and went to the dr who put me on Lexapro. After only 3 days on 10mg a day (low dose) I started experiencing serotonin syndrome. I hadn’t even heard of this or knew about it. Be careful some people are extremely sensitive and can’t take SSRI at all
Hello what are the symptoms of this ? can you tell me I hope you can see my comment and answer thank you God bless you I'm taking escilatopram too recently
Your doctor was kinda adventurous, usually they start you on 5mg and go up after 1-2 weeks to 10mg. Especially with panic.
Great... I have been on paxil for 25 yrs and been taking advil the whole time for chronic pain. 😬
thank goodness i rarely drink anyways, but i totally noticed when i drank after starting my medication that i was so SLEEPY like right away! it ruined my fun nights when i was too tired to function so i usually am the DD nowadays haha. kinda sucks tho...i wish i could get crunk every once in a while without worrying about the affects
OUTSTANDING VIDEO AS ALWAYS! Excellent content, my friend!
20 years of a rough ride.
Great video! Thanks for putting all of this in one easy to digest resource. Much appreciated.
Psychedelic’s definitely have potential to deal with mental health symptoms like anxiety and depression, I would like to try them again but it’s just so hard to source here
Psychedelics are the reason why i didn’t take my life when i was at my end. I was stripped of my ego and saw the beauty of life and interconnectivity and even though i still battle anxiety and depression, I’m doing better everyday and will never think in such a self destructive way again.
LSD and mushrooms completely changed my whole outlook on life. I became a better version of myself
This experience gave me a lot of confidence about my self and my body. A bunch of bad thought / behavior patterns were broken. One of these was pretty bad OCD that made me wash my hands a lot. It gave me a lot of hope that things will be fine, this is the one thing that I heard throughout the trip: Everything is alright. The main reason for the trip was my severe depression and it definitely helped me (although it's not gone). Before all I could do was lay in bed. Now I am trying to rebuild my life one step at a time which wasn't possible before."
[_James_tray]
Got psychs
@@sarahh321 Where to search?? Is it IG?
@@Jerryberger9235 Yes
Good lord Im glad I found this channel it was like was gods plan. I have some of those medications that increase serotonin syndrome risk and Im glad I didn't take them. Im going to talk to my pharmacist and see if there are other interactions because I have a lot of medications.
I'm on Lexapro 20MG and been robotrippin on DXM for a while. Good to know that I need to be a bit more careful. Currently the only affect I get from mixing the two is an upset tummy but I believe that's linked to seratonin syndrome
as someone who did the same thing in his late teens for about a year I will leave you this warning. it has caused me permanent neurological damage (I'm 33 now). don't mix ssri's and dxm
Dxm caused me permanent visual disturbances that have lasted 20+ years from a single dose of 420mg. I was 15 and on no meds. I had/have done many other drugs before and after - nothing ever affected me as negatively as DXM did…just stop. I’m not “anti drug” at all just “anti DXM”
Yeah...don't mix those