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Pharmacokinetics | Drug Distribution

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  • Опубліковано 17 сер 2024
  • Official Ninja Nerd Website: ninjanerd.org
    You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
    www.ninjanerd....
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be presenting on Pharmacokinetics, specifically discussing Drug Distribution. We hope you enjoy this lecture and be sure to support us below!
    Table of Contents:
    0:00 Lab
    0:07 Drug Distribution Introduction
    0:54 Factors Affecting Distribution
    8:00 Protein Binding
    17:05 Volume of Distribution
    25:25 Drug Distribution Practice Problems
    29:18 Comment, Like, SUBSCRIBE!
    Pharmacology Source:
    Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health.
    Join this channel to get access to perks:
    / @ninjanerdofficial
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    #ninjanerd #pharmacology #distribution

КОМЕНТАРІ • 165

  • @hesten9648
    @hesten9648 Рік тому +321

    I bet that I am not the only pharmacy student out there who is super grateful for these videos❤😂 Thank you so much!!❤

  • @colemanhelm6678
    @colemanhelm6678 2 роки тому +111

    These pharmacokinetics videos are coming out literally at the perfect time. Looking forward to metabolism and elimination.

  • @ahutamorris
    @ahutamorris 2 роки тому +18

    Now it's 3 years following you and I have gained a lot from you. Watching from Kenya (Nairobi).

  • @mikegox2275
    @mikegox2275 2 роки тому +36

    All your videos are very informative. You are the only person born in this world to help medical students, doctors, and even professors too. CONGRATULATIONS!!

  • @mohammedisak4645
    @mohammedisak4645 2 роки тому +11

    Masha Allah I'm from Somalia🇸🇴 We proud of You Me and My friends For your Hardworking Thank you For Your Helping us With Out you I'm sure that i can't know something About Medicine.
    Thank you.

    • @adiljb5943
      @adiljb5943 2 роки тому

      Hi bro also I'm here from somalia
      I'm in Mogadishu and I'm in mi 4th year of medicine without this professor I'm nothing

  • @alluparantha
    @alluparantha 2 роки тому +7

    You were put on this earth to teach. Honestly, thank you so much.

  • @jadec9733
    @jadec9733 5 місяців тому +4

    This needs to be added to the pharmacology playlist

  • @emaderecichei3712
    @emaderecichei3712 7 місяців тому +2

    I had been struggling to understand the protein binding drug until I saw your video. You are a very good teacher! Thank you and God bless you!

  • @humanicgenes8825
    @humanicgenes8825 2 роки тому +6

    Much love from Zambia 🇿🇲🇿🇲🇿🇲

  • @hussainahmad6457
    @hussainahmad6457 2 роки тому +4

    It was my desire to learn general pharmacology from u so now I m happy after seeing these types of lectures love from Pakistan kpk khyber❤❤

  • @brolistic87
    @brolistic87 Рік тому +2

    I'm studying occupational, safety and health. One of my required classes is toxicology, and this video is a lifesaver. God bless and Thank you for your contributions sir!

  • @chaitrakulkarni4716
    @chaitrakulkarni4716 2 роки тому +37

    Hi, I'm a pharm D student from India and your videos have been very helpful to understand the basics, and I'll really appreciate if you would explain a little about this pharm D course cause even though I opted this course I've been a little confused and couldn't get much info from our professors. So pls if you could consider helping me that'd be great. And thankyou for these amazing videos!

  • @mahmad1273
    @mahmad1273 2 роки тому +7

    MashAllah, brother Zachary. May Allah bless you more.

  • @poojajollin8647
    @poojajollin8647 Рік тому +4

    Hi .. I have been preparing for my Pharmacy exam and all the points mentioned here is very important to remember and is also easy to understand. I have been looking at diff other videos as well, but nothing as clear and well explained as this one. Thank you very much!

  • @kryptonite654
    @kryptonite654 Рік тому +1

    i am 1st year medical student and i am super grateful for your videos. It's helping me a lot to understand my course.

  • @AndrewSBoston
    @AndrewSBoston Рік тому +8

    I am a second year dental student and these are literally a GOD SEND! Thank you so much Zach and Company!

  • @ricknimusiima6571
    @ricknimusiima6571 Місяць тому

    Am doing pharm D, Dude you’re dissecting and simplifying every challenge I had in kinetics

  • @nouraraji1418
    @nouraraji1418 Рік тому +1

    I am a med1 student and its the first video of yours that I watch, definitely won't be the last .

  • @lindseyrhodes2739
    @lindseyrhodes2739 Рік тому +1

    just started pharm in pa school... perfect timing with these videos getting released!

  • @LondonBurg
    @LondonBurg 4 місяці тому +1

    An important concept about VoD to note is the definition of VoD: The APPARENT volume of distribution is the theoretical volume of fluid into which the total drug administered would have to be diluted to produce the concentration in plasma. It is not the actual volume that the drug is distributed within the body because that would limit the volume to apprx 42L in the average human. This is why we get numbers in the thousands.
    (Edit to include ex.): If you needed a drug to be at 100mg/L in the blood and you know the VoD of the drug is 200L you would have to give 100mg/L x 200L = 20,000mg or 20g of that drug to achieve the desired concentration in the plasma Assuming no first pass metabolism).
    please correct me if I am wrong. Happy studies everyone.

  • @stavhen7753
    @stavhen7753 Рік тому +3

    You're a life saver! thank you so much for the effort you make in making these videos!

  • @feliciasmith7170
    @feliciasmith7170 Рік тому +8

    You are simply incredible! Your teaching style, your content organization, and especially your doodle of a heart. Thank you again for sharing your gift!

  • @charlesfavour5640
    @charlesfavour5640 Рік тому

    Thank you sooo much Zach and the whole Ninja Nerd family. You are a blessing to students worldwide.
    From Calabar, Nigeria.

  • @muhammadsulaiman6023
    @muhammadsulaiman6023 2 роки тому +2

    Zach you really made it easy.

  • @wizonceluv6377
    @wizonceluv6377 2 роки тому +2

    I literally had this lecture today!! great timing!

  • @elijahkurien9941
    @elijahkurien9941 2 роки тому +6

    At the end of the unit could you do a video on a case study on a drug like Tylenol or Aspirin and how its pharmacokinetics affects its distribution?

  • @Magnificento03
    @Magnificento03 Рік тому +1

    thank you so much Ninja , its really helping. i wish you were my teacher.

  • @soul8156
    @soul8156 2 роки тому +2

    You are the best, thank you so much 💚

  • @iamsufyanali
    @iamsufyanali Рік тому +1

    You can be the best teacher in the world. I just love your videos. They really are helpful. Can you please make videos on the remaining topics of the LIPPONCOTT?

  • @marouanelsayed4976
    @marouanelsayed4976 2 роки тому +2

    the coolest doctor in the galaxy ❤

  • @missh6773
    @missh6773 2 роки тому +3

    Thank u so much you are Amazing as always ,,please do more of pharmacokinetics videos and solve more questions ❤️❤️❤️❤️❤️💐💐💐💓💓

  • @bradwarr7570
    @bradwarr7570 2 роки тому +2

    Great brother, really like the new style and podcast type questions at the end.

  • @jhoanrodriguez7496
    @jhoanrodriguez7496 Рік тому +1

    Beautiful lecture. You are saving me in PA school :D

  • @petarvukelic2091
    @petarvukelic2091 2 роки тому +3

    Can you please do a video on gaba receptors and glutaminergic receptors? Thanksss!!!

  • @forozanmo7520
    @forozanmo7520 Рік тому +1

    Please make more lectures. You explain very well

  • @tsabeehadel9754
    @tsabeehadel9754 2 роки тому +1

    You are agift to humanity zach 🌷
    Thanks

  • @rileypage1109
    @rileypage1109 8 місяців тому

    Thank you so much! This was incredibly helpful. This video just made my day! You are an angel sent to help me succeed in PT school. Keep up the amazing work!

  • @reema1761
    @reema1761 Рік тому +1

    Man you’re a life saver !!!! THANK YOU

  • @yogireddy7209
    @yogireddy7209 Рік тому +1

    Very understandable and easy to remember thanks 😊from Indian doctor

  • @hajarb4588
    @hajarb4588 Рік тому +1

    Thank you so much

  • @user-vu5yh4iq8o
    @user-vu5yh4iq8o 11 місяців тому

    You, my friend, are an absolute legend.

  • @makemoneyonline_888
    @makemoneyonline_888 2 місяці тому

    Thank you so much for these videos❤

  • @anikarahman5467
    @anikarahman5467 Рік тому

    He visualizes better than animation.
    Hats off.

  • @josephgrantabbam4618
    @josephgrantabbam4618 Рік тому

    Very simplified and easy to understand. Thanks bro

  • @forozanmo7520
    @forozanmo7520 Рік тому +1

    missed distribution part in class
    Thank you for explaining

  • @pascalinamulu5307
    @pascalinamulu5307 2 роки тому +2

    Thank you soo much, you have explained it so well, l now understand. Looking forward for you to do Metabolism and Excreretion videos because l have exams next week 🙏🏿

  • @kayareii9446
    @kayareii9446 Рік тому

    3rd year pharmacy student here u rockkkkkk!!!!!

  • @sabzzz444
    @sabzzz444 Рік тому +1

    What determines whether a drug wants to be bound to albumin or not? Thanks for the video, amazing as always!

  • @evasimeonova5381
    @evasimeonova5381 Рік тому

    Very useful and simply presented. Thank you🫶

  • @hidayatullah873
    @hidayatullah873 2 роки тому +2

    Kindly complete pharmacokinetics as well pharmacodynamics

  • @shafiullah8965
    @shafiullah8965 4 місяці тому

    Wow Zack really makes confusing topics So easy ❤❤❤❤ Gratefull To you and your team members .

  • @dhivakardharmeswaran4020
    @dhivakardharmeswaran4020 6 місяців тому

    We are God's gifted to listen to your videos.

  • @molanaroomi7431
    @molanaroomi7431 5 місяців тому

    Sir along the study we also laughing .....great sir

  • @lenal6342
    @lenal6342 Рік тому +2

    It was awesome! thank you so much.
    I have a question please: regardless of the following factors affecting the distribution, how to know whether I need the drug to be highly distributed or not into the bloodstream?

  • @dent0osh
    @dent0osh Рік тому +2

    Your videos are the best! I can’t thank you enough 🥺✨✨
    But wish this video was in the pharmacology playlist after absorption video.. it’d make it easier for us to find it 🤍

  • @ogbeidekelvin
    @ogbeidekelvin 2 місяці тому

    Thank you leader

  • @anwarbajwa9702
    @anwarbajwa9702 9 місяців тому

    Very helpful
    Thank you 😊

  • @user-tn2ft7zt5j
    @user-tn2ft7zt5j 5 місяців тому

    Best clere vidos for drug distrbution thanks

  • @negasumelaku6083
    @negasumelaku6083 10 місяців тому

    thank you Dr.

  • @nikolaivikturski4557
    @nikolaivikturski4557 2 роки тому +1

    Thank you for another video 😊😊👌

  • @nkechimakata3254
    @nkechimakata3254 7 місяців тому

    Thank you very much sir

  • @salimseleman4552
    @salimseleman4552 3 місяці тому

    You are super Genius 🔥✊ Thanks so much🙏

  • @nena2172
    @nena2172 9 місяців тому

    You are really really saving us ,thank U so much ❤

  • @mohamedkhalid306
    @mohamedkhalid306 2 роки тому +3

    Add this one to the pharmacology playlist, looks like you forgot it

  • @fatimaqueen5372
    @fatimaqueen5372 7 місяців тому

    super conceptual video

  • @najyakawsar5708
    @najyakawsar5708 2 роки тому +2

    Professor pls cover all Pharmacology topics we need such explanation I mean the topics which is still not covered by u in Pharmacology.

  • @irtamalik1778
    @irtamalik1778 5 місяців тому

    Your "nooo" after 16 mins made my day. Stay blessed ❤😂

  • @sedasoon
    @sedasoon 4 місяці тому

    Another amazing video

  • @Alien61747
    @Alien61747 6 місяців тому

    Thank you so much 🙌

  • @ladypinoy7352
    @ladypinoy7352 11 місяців тому

    this is super helpful and engaging! thank you, you beautiful soul ❤

  • @Die_Empty.
    @Die_Empty. 2 роки тому +2

    NINJA you forgot to put this vedio on your playlist😯

  • @userno695
    @userno695 Рік тому

    Thank you for all these lecs they are very helpful
    I also really liked this shirt i want one

  • @doniamohamed8132
    @doniamohamed8132 4 місяці тому

    you're a life saver!!!

  • @rumaisariyaz4157
    @rumaisariyaz4157 2 роки тому +1

    Could we please have a video on Amoebiasis
    Love your videos!😍

  • @tseyangdorji8689
    @tseyangdorji8689 2 місяці тому

    Thank you!

  • @Coconinga
    @Coconinga 11 місяців тому

    Excellent

  • @pascival6468
    @pascival6468 7 місяців тому

    You are a life saver

  • @sreejacharanya1460
    @sreejacharanya1460 2 роки тому +1

    Thank youuuuuu sir

  • @user-iv8bd6ze5k
    @user-iv8bd6ze5k 2 місяці тому

    So helpful ❤

  • @angelpetersvlog2337
    @angelpetersvlog2337 Рік тому

    Thank you

  • @priyambadabejladdumotu3389
    @priyambadabejladdumotu3389 Рік тому

    This video was so much fun

  • @Medperfect
    @Medperfect Рік тому

    thank you

  • @asadullahkhan8727
    @asadullahkhan8727 Рік тому

    I didn't just give the like, You actually earned it Bro❤️

  • @harivigneshumasankar3050
    @harivigneshumasankar3050 Рік тому

    Enjoyed this!

  • @onejihanwasfi
    @onejihanwasfi Рік тому

    You are my hero, thank you ❤

  • @letsthink2599
    @letsthink2599 8 місяців тому

    2nd yr physiotherapy student here and i know i would have failed without zach

  • @17asishkumardas47
    @17asishkumardas47 2 роки тому +1

    Please upload Antileprosy too

  • @fatimanaveed5269
    @fatimanaveed5269 Рік тому

    Tysm ❤

  • @dibyasattwakarmakar
    @dibyasattwakarmakar Рік тому

    Thank You , Sir 😊

  • @rawanshaker6631
    @rawanshaker6631 10 місяців тому

    thank youuu for ur videossss

  • @042mohankarnati9
    @042mohankarnati9 11 місяців тому

    If anyone sees this this I need a doubt answered albumin is a charged molecule so that also says that the drug bound to albumin is also polar so how does the albumin act as a reservoirs if the drug is ionicly bound to it?

  • @gibrilladumbuya355
    @gibrilladumbuya355 2 роки тому +2

    Hey Zach can you please do a video on Amniotic fluid embolism secondary to DIC
    More on the physiopath and management
    Texting from Sierra Leone 🇸🇱🇸🇱🇸🇱🇸🇱🇸🇱

  • @dinaayad4891
    @dinaayad4891 7 місяців тому

    amazing amazing

  • @iamsufyanali
    @iamsufyanali Рік тому

    I just love your videos.

  • @musharafkazmi7550
    @musharafkazmi7550 Рік тому

    Thank you ❤️

  • @alderamin1402
    @alderamin1402 Рік тому

    THANK YOUUUUUUUU

  • @aarjanyt8485
    @aarjanyt8485 Рік тому

    You haven't put this video in the Pharmacology playlist section 😭 I watched so many other videos on distribution because i couldn't find it there

  • @ioanarotariu136
    @ioanarotariu136 Рік тому

    thank you a lot

  • @rawanabbas6919
    @rawanabbas6919 Рік тому

    Can’t thank you enough 💕💕💕💕💕💕💕💕💕

  • @jaymjay2313
    @jaymjay2313 Рік тому

    Very clear as crystal..