Does the New Weight Loss Drug Wegovy Lead to Weight Loss?
Вставка
- Опубліковано 2 чер 2024
- Today we're talking about Wegovy, which is a new prescription drug approved to treat obesity. It's also called semaglutide, and it was initially approved to treat diabetes, but studies have indicated it is effective for weight loss. There are a few side effects to be aware of, and it's also pretty expensive. Find out all about the drug and the studies in the video.
Related HCT episodes:
Ivermectin is Not an Effective Covid Treatment: • The Research on Iverme...
Be sure to check out our podcast!
• Podcast
Other Healthcare Triage Links:
1. Support the channel on Patreon: vid.io/xqXr
2. Check out our Facebook page: goo.gl/LnOq5z
3. We still have merchandise available at www.hctmerch.com
4. Aaron's book "The Bad Food Bible: How and Why to Eat Sinfully" is available wherever books are sold, such as Amazon: amzn.to/2hGvhKw
Credits:
Aaron Carroll -- Writer
Meredith Danko - Social Media
Tiffany Doherty -- Writer and Script Editor
John Green -- Executive Producer
Stan Muller -- Director, Producer
Mark Olsen - Art Director, Producer
Eliot Rapoport - Contributing Writer
#healthcaretriage #weightloss #wegovy
Shout out to Eliot Rapoport, our contributing writer, who did the heavy lifting for this episode!
Having the study titles in the video is great, thanks for that.
Can you also add links to them, or at least their abstracts and methodologies, to the description or in a pinned comment?
Is there any weight gaining drug?
@@erutanevoli Weed?
On wegovy for 8 weeks, at 0.5mg now. Started at 375, at 333 right now. No side effects.
Awesome weight loss! 👌
My doc prescribed this to me and I’ve lost 15lbs in 3 months. I nearly cried when Infirst started the medication… no preoccupation with food and now eating a mostly healthy plant based diet. My BP is down and my knees feel great! I hope more insurances start covering th
Congratulations!!! That’s so awesome!
I think that sometimes it's a matter of needing an extra push and drugs like this could provide that push. Obesity feels like a very hopeless disease because weight loss is a real slog, and the food that you've been literally addicted to doesn't, on a per meal basis, make you gain all that much weight. And yet giving up that food that you're - again, literally addicted to - feels so miserable, all while the scale barely moves week after week.
Congratulations! I'm glad it's working for you.
that is awesome! I wonder if the drug will help people change their setpoint by allowing them to stay at the new weight for long enough.. so that they can come off it and find it easy to maintain a weight that is more comfortable for them
I am so glad to see that this worked for you. I will start my injections this week. Did you experience any negative side effects?
Better than sliced bread! I have lost 40 pounds in 6 months on Ozempic, which is the same thing as Wegovy. But what's even better, is that my A1C and liver enzymes are almost completely normal. Yes, the first couple of months were brutal. Felt nauseated and had an odd side effect that I didn't hear about, which psychologically I just felt numb. But after that 2nd day of the shot, felt completely normal. If you're taking it, hang in there. It's so worth it.
I'm on wegovy! I lost 8ish pounds the first month without changing my diet at all. It sucks that a lot of insurance doesn't cover it, and that it costs so much.
How is it going for you now?
How many days the 2.4 W pen will Last?
I’m on Wegovy! Tomorrow I star my 2nd month at .50. TOTALLY suppresses my appetite & I have zeroooo cravings! Down 17 lbs!!! I’m loooooooving it! Mild to no side effects on .25, hoping I don’t get any on the new dose…IT REALLY WORKS!
Damn what insurance do you have? Mine is $150 I haven’t started yet- I’m so happy for your weight loss
@@Cupcake40 yikes, wegovy costs me $5 for a 1 month supply.
@@josephackerman9628 that is amazing! I did end up getting it for $45 with a savings card.
@@josephackerman9628 how come you got it that cheap? X
@@mckenna9489 I think it has to do with that I am getting it through the weight loss clinic at the hospital I work for and as employees they are giving us a 40% discount, plus discount at our pharmacy. Honestly felt like not posting how much I am paying d/t costs others are having to make, feel very lucky in that regard
I am a recovering addict after getting sober I gained 75 pounds nothing I did would help me my doctor put me on this I’ve now taken it for a month I’m down from 275 to 261 this has been a lifesaver I was getting so uncomfortable with my weight I had contemplated going back to using
Glad it worked for you so you didn’t have to go back to using. Weight gain and weight loss can be huge stressors. Wishing you continued success and strength. 💪🏾
Holy s--t, pretty hyped for this one, reduced appetite sounds like something that could help in a load of different ways to a lot of struggling people.
Might even work to help with the transition to better feeding habits when used only for a period of time, like training wheels.
Without the drug, I lost 120 pounds!!! She was a 5 foot 5 blonde and left me because I was fat.
Thanks for pointing out that the observed effects (other than "physical functioning") were in surrogate rather than clinical outcomes, and that evidence for health benefits of weight loss is not evidence for health benefits of weight loss with this drug.
At that price tag, I certainly hope that in future they can demonstrate some very significant clinical outcomes.
I'm taking this now. Have lost about 20 pounds in 2 months, but the side effects are brutal. It's been really difficult to get as it's being prescribed so much. Since my insurance covers part of it, I was able to use the coupon and get it for $25/month. For me, it mostly keeps me feeling full, so I'm eating smaller, more frequent meals. If I let myself get too hungry or too full, I'm sick for days. Figuring that out has helped my side effects a ton.
I'm on Ozempic so I can imagine. Couldn't function for a few days. Helps to give shot in leg instead of stomach. I probably will go back to stomach though as my 0.5 may not be working as well. I do get sick if I overeat now. Like in pain and sick sick 😷
@@ms.dirtybird7779 I did find that the leg helped! I'll be moving to the highest dose (2.4) today and it's gotten a lot better. I have noticed that my body has maybe gotten used to it or something, though, because my rate of weight loss has dropped significantly. Still losing, it's just taking way more work now.
@@IMakeupStuff awesome! I'm glad it worked. I read a comment and found that out too.
@@IMakeupStuff my a1c has actually gone down 2 points too. But those side effects...brutal!!!! I had to call in sick the day after my first dose.
What are your side effects?
I started taking Wegovy in December and I’ve lost 70 pounds since then. Spoiler alert: it WORKS
Do you get nausea? I just started last week at 1.0 and I'm so ill
@@kelliwomack3737 no. And even if I did I would be happy to get nauseous for the amount of confidence it’s given me. It would be an easy trade off.
How much is it
I've definitely encountered social and psychological challenges because of my weight. (bullying since age 3 mental health challenges suicidal thoughts and loneliness as an adult). I've already lost a fair amount of weight but It's not good enough. I'm hopeful that this can help and help me be a better person.
Thanks for the interesting video! Wish patients had more access to resources for weight loss. I had success will a nutritionist but I’ve also been prescribed metformin which has weight loss as a side effect. I like how you mentioned the societal and economic impacts on weight as well. Also I was on some medications (prednisone) that make people gain weight. Think it’s important to explore options for weight loss because it’s not always just a matter of eating less. PS. I’m off the diabetes meds and my A1C is good!(also lost 50 lbs)
How long did it take you to lose the 50 pounds I got a prescription that I have to pick up on Monday I was 140 and now 197 id love to lose 57 and get back to my weight
@@Jboogie692004 It took me a long time but just choose a diet that you can stick to and don’t expect to lose the weight all at once. Also making substitutions with healthy foods. Like instead of substituting rice with cauliflower rice or even a sugar cereal with oatmeal or something. I also found that it helped to weigh portions out on a kitchen scale and keep a food tracker on my phone. It’s kinda a pain to weigh out everything but it helps if you need to track carbs. Good luck!
Why didnt you explain how this medication works? I would be very interested in that.
For $1300 a month, the drug would need to actually enter my cells and eat the fat while I sit on the couch and eat Cheetos. The behavioral interventions probably had more effect anyway. People who get fat don't stop eating when they're full or eat only when they're hungry. They do it because food is delicious and they're looking for short-term happiness or to sooth negative emotions. If a person doesn't change their behavior, this drug will have little to no benefit.
Your wrong. As someone who takes part in this drug, I can tell you that it is a different kind of feeling. For example, instead of a heavy set person getting full but keep eating, the drug actually penetrates a feeling of fullness to the brain that is more powerful than usual. And if that’s not enough for someone who hasn’t mastered portion control, the more the user eats OVER the appropriate amount the more nauseous and uncomfortable they get. So the drug works and btw mine is 1600 but I pay $25 bucks hehe
😂
Eight
1300 lol I when to get my medication yesterday I had to walk away 1300 it’s to much for mke
I've constantly struggled with weight and just given up at this point. My goal is to eat healthy, lots of leafy green, lean protein and low sugar and ignore the scale. I don't know why I'm fat, and no one else seems interested in finding out.
I think the trick to weight loss is to notice that you think of food as an activity that you should enjoy.
It isn’t.
Food is for energy and nutrition not enjoyment.
We enjoy food for evolutionary reasons which no longer benefit us in a good assured environment.
@@adamkatz6532
Meh trick to me was realizing how/when I ate. I had trained myself that watching tv/movies/etc needed food. So watch something? Better snack.
That was a very hard habit to break.
@@adamkatz6532 lol what a dour way to go through life.
@@adamkatz6532 The idea that metabolically disadvantaged people need to restrict, control, alter, or eschew foods separates them from more metabolically advantaged people. Imagine you were told that your weight was your fault, and that when you eat less calories than others, stress about when to stop, and deny yourself what other people gain satisfaction from that you don't get that food is energy. There are for sure people who over eat, its a real problem, but separating eating disorders from obesity is necessary to understand and treat the epidemic. Food is a part of our culture; advertising inundates us with images of food and the message that eating will make us feel good, and it will! Telling a subset of people that pack pounds on easily because of systemic cultural, economic, and emotional factors that they are the problem because they don't "get" how food is supposed to be consumed is short sighted at best and dangerously bigoted at worst.
@@daltongrowley5280 the difference between the extreme ends of the 'healthy' metabolic rate spectrum is approximately 200 cals a day, and people vary within that range themselves. Diet and exercise are just so much more likely to be the predominant factors for the vast majority of people.
It's also extremely worth considering the shortage and how it's needed for diabetics
Was trying to figure out what Wegovy is locally because semaglutide sounded familiar. In Israel we have it under the brand name of Ozempic, and it has shown some fairly promising results. I wish I could try it myself, but currently our Health Ministry has restricted to only diabetics. Hopefully that will change soon. I already did a vertical sleeve gastrectomy two years ago and amid all of the fun of COVID-19 I'm nearly back to my pre-surgery weight.
Also, if you have a problem with thyroid is it contraindicated or should you have certain thyroid tests monitored regularly while on it?
In Australia this drug has been put on PBS but only for diabetics, I don't think that's fair. For lots of people that are obese this could be life changing but they can't afford to pay full price. My Husband only pays $6.50 for his prescription to be filled where a person without diabetes has to pay over $1000. My Husband developed type 2 diabetes from years of overeating and drinking gallons of coke, he still does; how is it fair that he's able to get this drug cheaper than an overweight person without diabetes?
My doc told me that When we over eat, there is a hormone Produced in the stomach that sends a message to our brain Telling it that we are satiated or full. For people who over eat, The body gets so used to eating that it stops Producing this hormone and we don’t get a feeling of satiation or satisfaction from the food. This hormone that is produced does not last long, so if we stop producing it we still feel hungry in our brain even though our stomach may be full. This drug produces these hormone cells and they are engineer to last longer than our natural ones. This triggers a feeling of fullness in our body and brain for long periods of time telling her body not to eat. So people can lose or begin to have inhibited Sensitivity to food in our stomachs. This drives us to want to eat more because this hormone is lacking in our stomach.
If it has the appetite suppressant capabilities of phentermine without the side effects, that's a huge breakthrough. The other problem with phentermine is that it would just.... stop working for some people after a few months. I had a lot of success with phentermine, but I want to talk to my doctor about trying this if at all possible since we had to roller coaster with phentermine and the first week on that drug was always absolutely brutal.
I wish they had had a group that had no intervention. Just the shoot.
Thanks for the video. Would love learning more about the problems caused by bariatric surgery. For the common people it is extremely hard to find information about its side-effects, how many people go back to their being obese or what other health issues they develop afterwards. I have been looking for my brother and could not find much yet heard from many who had it done of many negative outcomes. One friend almost died, too. Yet, nothing I could find accessible to the general public about. Please help!
Stay away from all unnecessary surgery. Stop eating highly processed foods high in carbs & sugar. Switch to a high fat diet. Salmon, grass fed beef, avocados, eggs, bacon, grass fed butter, olive oil, walnuts. Stop eating 3x a day. Only eat 1 time a day until you’re comfortably stuffed (better to overeat 1x a day than under eat 6x a day). When you are accustomed to eating 1x a day try going on a 2 day water fast. A week later try a 3 day water fast. I wouldn’t go longer than 7 days of water fasting & if doing a 3-7 day fast I would only do it once a month. If you get cravings or hunger during the day then it means you didn’t eat enough fat for your 1 meal the day prior. Do not be afraid of fat, it is your friend. Carbs & sugar & snacks are the enemy. Healthy fat (no vegetable oil, only grass fed meat & butter). Hope this helps. If you want more info research Jason Fung & Eric Berg. I also listen to Mindy Pelz & Ken Berry.
I’ve lost 35 pounds, cured fatty liver, leaky gut, gastritis, high blood pressure, pre-diabetes by eating a high fat diet 1 time a day combined with 3 day water fasts once a month. Cut out all processed sugar, gluten, pasta, bread, vegetable oils, snacks. I lift weights every other day (to keep muscle mass) right before I eat my 1 meal of the day. This will greatly increase the benefits you get from exercising. If you have more questions let me know.
@@JC-li8kk
Nobody asked
@@oliverwilson11 So what does “Please help!” mean?
There are very few complications with the gastric sleeve. The other surgeries that rewire the intestines are the ones with complications. To much sugar or fat in a meal can make a person with this surgery ill, vomitous. And they have GI issues. But they lose more weight than GS. Maybe an extra 50 pounds more so to some really obese people it's worth it. I got the gs because it has minimal side effects and you can always go back and do the intestinal rewiring later if you regain weight. I've only regained 7 pounds in 4 years.
This is pretty neat, I hope it proves effective at changing brain chemistry permanently at some point. Would be great for all the people with various ailments keeping them from reaching a healthy weight.
Heads up people, an daily oral form of semaglutide is currently available, and everything lets us suppose it will have the same effets as the weekly injection on appetite suppression and weight loss.
Bad news, even when the patent expires, the molecule will still be expensive to produce, and we can't expect the bio-similar off brand products that will be available in 10 years to be cheap either.
I'm looking into this but am curious what the average weight loss is. Wouldn't it be better for the clinical trials to be using Wegovy only rather than in addition to diet and exercise, or else maybe have one group do Wegovy only and another comparison group do diet, and another just exercise to see how much weight loss could be attributed to the drug?
That exactly what I’m thinking. It’s not like drastic weight loss that one couldn’t get from a healthy calorie restricted diet and exercise.. so I’m struggling to see the cost-benefit. Also- what about those who eat even when they are not hungry/already full? If it’s just an appetite suppressant, doesn’t seem it would help them much…
My gallbladder was removed so I don't have to worry about that side affect.
Might have to see if I can get it covered to help me lose weight and make it easier for me to transfer in and out of my wheelchair and to move around.
may be a useful tool for some, but it also a potential cash-cow for the drug company. I'll stick to a low-carb diet instead.
3:32 Theeeeere it is. I'm convinced at this point that "weight loss as a medical intervention" is a boondoggle at this point if the best we can do outside of major surgery is "stay on this drug/plan/regimen for the rest of your life."
How do you know it's not going to help some people, maybe by a lot? Dismissing the entire idea of drugs aiding weight loss is not helpful at all.
@@gyozakeynsianism well there just doesn't seem to be any evidence that weight loss helps health outcomes and there is a lot a lot a lot of evidence that dieting causes worse health outcomes and results in weight loss for only between 2 and 5% of people
Think of this example:
Thin woman goes to doctor with high blood pressure, gets blood pressure medication.
Fat woman goes to doctor with high blood pressure, gets no medication, is told to lose weight instead.
Doctor sees study saying that thin people with high blood pressure have better outcomes, assumes he made the right decision.
Do you see what's wrong with that picture?
@@therabbithat No that's not true. There is evidence that weight loss is an effective treatment for sone diseases and good at preventing some diseases. The NIH has loads of recent studies. Doctors are not wrong to prescribe weight loss to their patients. It has its own casual effect on health. Diabetes is a major example.
It's true that you can be overweight and still have good heart health, but that's not common and that's nowhere near the whole story.
As a t2 diabetic taking Ozempic (also semaglutide), who also has dealt with obesity my whole life, is there any difference beyond dosage range and FDA certification between Ozempic and Wegovy?
TL;DR: Differences between Ozempic and Wegovy, beyond dose and indication, is you may get slightly more weight loss and higher chances of side effects with Wegovy compared to Ozempic. They are essentially the same drugs, Wegovy just has higher dosing.
Dosing for Wegovy is 0.25 mg titrated to 2.4 mg weekly for weight loss. Dosing for Ozempic is 0.25 mg titrated to 1 mg weekly for diabetes. In the STEP 2 trial, they compared once weekly 1 mg and 2.4 mg dosing with placebo in patients with obesity and diabetes; the 1 mg and 2.4 mg groups lost more weight compared to placebo (6.9 kg for 1 mg, 9.7 kg for 2.4 mg, and 3.5 kg for placebo).
So you'll most likely lose weight whether you're on 1 mg or 2.4 mg just by virtual of how the the drug works (inhibits release of hormone that signals body to produce sugars, slowing the emptying of food from stomach, and increases how satisfied you feel after eating a smaller meal). The 2.4 mg dosing comes with more gastrointestinal side effects so some people may not tolerate the higher dosing. Given that the drug is blood sugar dependent, there is low risk for it to drop blood sugars dangerously low even in people with normal blood sugars, which is probably one of the reasons it can be used for patients with or without diabetes.
@@WrathOfEnd Thanks for the detailed reply! I'm currently still early in titration (just was diagnosed a few weeks ago), so I'll definitely need to speak with my provider about what my target dose will need to be.
@@wesskinner Given that you're using it primarily for diabetes, 1 mg will most likely be where you would max. Higher doses isn't indicated for diabetes so your insurance may not cover the med for weight loss purposes.
Everyone should listen to Maintenance Phase who watched this video.
My doctor tried to prescribe this to me, but my insurance refused to cover it since I don't have diabetes.
How do I get my insurance to pay for it, or at least part of??
Hello all is any insurance cover these medications?
I don't know, I'm into my second month of Wegovy and I've increased about five pounds and still haven't seen much weight loss take into effect. I don't eat massive amounts of food, because the Wegovy does surpress my appetite but I do eat some processed food. I know we still have to diet and exercise while on Wegovy, but for me this med hasn't worked as other folks.
It does work. In my experience I lost more in the first month, with high hopes that it would continue. It has averaged about 5 lbs a month. That being said, it's a safe amount to lose. With whatever food you put in, you will naturally fluctuate a few pounds. I weigh in every Wednesday and wait to eat or drink until I've had a bm and then weigh myself. I think that's my true weight. This medicine really reduces appetite (thankfully). If a craving comes in, I go for popcorn or something less invasive. Really helps regulate insulin, and I'm under a lot of constant stress, so it really helps my insulin resistance. My only side effects have been constipation, heartburn indigestion and some fatigue. To combat this, I eat more fiber (I'm vegetarian, but work on eating more veggies) and good oils (olive oil and avocado oil), I take a prilosec t,w,th,f and that combats the indigestion. The fatigue, it comes and goes. Sometimes I use C-4 (pre-workout powder), and I only take half a scoop (which is really strong, I'd recommend starting with a quarter scoop. The label says to take a whole scoop, but I never have. It's really strong). In three months exactly, I've gone from 270 to 254. It's not safe to lose faster. If I was able to exercise more, I'm sure I'd have better results. I've tried to switch to stevia for my intake of sweets, remove as much flour and wheat as I can (gluten free products seem to work well enough and taste good), and dramatically reduce dairy. I don't eat meat anyways, so my protein intake has always been on the lower side, but I do protein shakes and smoothies (fruit, oat milk, stevia, ice and water then blend).
My one suggestion, would be a buddy system or a support group. There will be times the scale goes up a couple pounds for a few days, and that is when you really start stressing that the medicine has plateaus, and then a week or two later you start seeing results again. If you have the energy, keep a diary of both weight and food consumption.
Wouldn’t you get those same results from just your explained diet and walking/exercise?
Peptide Science is amazing
Why are people saying not to start this until fall of 2020 because of shortages
Is this similar to metformin?
Nikado Avocado needs this drug ASAP!
Great episode! I’d love it if you could do one on whether soy is dangerous for men (and specifically their brains!).
i think they did one?
spoiler: it's not
check out any dietician on youtube or social media, they probably have a video or post debunking this
(dieticians (RDs) are food / nutrition / health experts, nutritionists are usually not because anyone can claim to be a nutritionist)
I was on Ozempic at the full dose of 1mg for 3 months and lost no weight at all. I was eating less and exercising 5 to 7 days per week.🤷♀️ I was extremely disappointed. Clearly this doesn’t work for everyone.
The therapeutic dose is 2.4mg for weightloss.
*If You Have More Than 15 LBS To Lose Then You'll Want To See How This Fat-Dissolving Outback Loophole Can Change Your Life: **ua-cam.com/video/ECWTqmnPoJc/v-deo.html* 😃
My Insurance won’t pay for it
Reality Check: Even Medicare is refusing to pay for some medical tests for people who are too Old (Over 70) and too Young (Under one year old). In the United States this is a National Disgrace...
Man the nausea is bad with this medication for a while
Had to start at a high dose because the low dose was not available for months. Made me vomit for 3 days noon stop. Had to go to E.R to get help to stop vomiting. The side effects are unbearable. Deff Made me lose weight. Was to sick to eat. I’ll never take it again.
"Insurance companies have historically dragged their feet when it comes to obesity treatment"
For profit insurance companies should not be legal in the US.
Not only is that massively immoral it's also bad capitalism.
Treating obesity, or any health issue, before it gets bad and exacerbates other health issues is cheaper in the long run than trying to avoid treatment until it's a big problem.
Most of those historic meds are dangerous is the thing. It's not a straight forward benefit
Is it possible to be "healthy" and obese? Eg you're active and eat well, and all of your bloodwork etc comes back normal. I've seen arguments that increased negative health outcomes in obese people is, in large part, actually from discrimination from the providers. Would love to know what the research says!
No
No
no
It may be possible in rare cases. But the immediate physiological harms are much greater than neglect by providers. That said, the latter is still a huge issue.
Just do your best. Stay away from sugar and white bread, eat lots of leafy greens, and lean protein. You still might be obese, but not as obese as you could be.
Just yesterday my doctor prescribed this to me, my insurance won't cover it and it's $1,600. 😭😭😭
Ridiculous of the price, 1700.00 per month.
I’ve been looking into doctors who specialize in diabetes control and fasting and intermitting fasting does help to reset the body’s digestive system back to more sensitivity. I have been trying to fast regularly and I do notice that I get full much faster now. I and I am more aware when I eat what exactly I’m eating. And I don’t wanna put crappy food in my body because now I am truly hungry and I crave better food. And I also take chromium picolinate and because a deficiency in this vital mineral can cause sugar cravings. I learned this many years ago and every time I would take it my sugar cravings would drop about 70% of what they normally are. I also use cinnamon a lot which helps lower blood sugar and insulin sensitivity. I hope this helps someone out there.
I'd love to see a video on alpha yohimbine/rauwolscine (overthecounter) or clenbuterol
I always feel hungry, even when I know I'm not... and that sucks.
That's one of the things I learned from fasting - I eat when I'm bored, not when I'm hungry.
I feel the same way. But so long as I satisfy my hunger with healthy things like leafy greens, lean protein, healthy fats, and stay as far away from high glycemic foods like sugars and white rice, then I feel like my weight won't doom me.
That’s because you’re eating high carbs high sugar. Switch to a high fat diet & you’ll be able to go longer without being hungry & you’ll lose weight because the body burns fat you consume but stores sugar & carbs as fat. Try to only eat 1 or 2 times a day within a 4-6 hour window. I only eat 1 time at 6pm every day. No snacks. I do 3 day water fasts once a month to heal any diseases I’m unaware of, eat up any excess body fat accumulated over the month & increase my appetite for fatty healthy nutrient dense foods (you won’t want to drink a soda or chips after a 3 day fast. You will crave foods high in fat & nutrition).
@J C Oh great, thanks random UA-camr for giving away your medical wisdom. We trust you implicitly.
@@gyozakeynsianism indeed
Sounds like every other drug and diet unfortunately. That when not continued, weight loss and maintenance will stop.
Lol only America would struggle providing people weight loss meds due to high prices 🤣
And it's especially needed there.
No
What is the data that suggests intentional weight loss has positive health effects?
Also - are there any studies on how often weight loss efforts are successful over time? Also - are there any studies on what effect gaining and losing weight has on health?
This lines up with the fact that many folk don't get the same signals telling us when we are full, or how much energy reserves we have and if we need to eat and so on. This appears to have a strong link to genetics, and our hormones and brain receptors. So it's nice seeing treatments focusing on that and not 'OMFG WHY CAN'T YOU JUST EAT LESS OR EXERCISE YOUR ENTIRE LIFE AWAY'. Which. Not helpful to a lot of folks on a long term basis. I refuse to cut off half my stomach, and I refuse to spend my life hungry. So things down this path are welcome and hopefully will improve over time.
It all has to do with diet. When I was eating high carbs high sugar I was hungry all the time & my body would store it as fat (so I wasn’t hungry because my body needed energy reserves I was hungry because my brain wanted the dopamine it got from sugar). Once I switched to a high fat diet I no longer get hungry for 24 hours. It’s just like a drug. Once you start it’s hard to stop. But those who never start have no cravings for such a drug. So the hardest part is breaking the sugar addiction. If you want to know if you have a sugar addiction then try eating everything but sugar & refined carbs & you’ll find out real quick.
If you aren’t overweight then you can eat when you get hungry. If you are overweight then you’d be insane to keep eating when you know your body has fat stored that it can feed on. It’s 100% a psychological battle. Nothing to do with genetics. Anyone who is overweight can simply stop eating until their body feeds on all the stored fat. If satisfying your temporary dopamine craving is more important to you then you’ll always be overweight & continue to store more & more fat.
Helloo
$1,300? Uhhhh.
it's semAglutide, not semiglutide
Healthy Keto and Intermittent Fasting lifestyle.
Yes after paying 1300 hundred for the drug you can no longer afford food. Works like magic. 😂
Holy cow! Lovvvved your comment! 😂😂😂😂😂😂😭😭😭😭😭😭
😅😅😅😂🤣
semaglutide
My gallbladder was removed, I wonder if that would make that side effect null. If my insurance covered it, I’d take this medicine.
This isn't about weight loss.
The side effect of cholecystitis (gallbladder inflammation), something very rare anyway with this drug, would not be a concern for you, yes.
BUT, Wegovy's most common side effects are nausea, vomiting, diarrhea, and/or constipation. These are not dependent on having a gallbladder. These side effects don't occur for the majority, and usually lessen or dissipate completely after a few weeks of taking. However, some people discontinue because they can't tolerate it.
If/when your insurance does cover it, it's worth a conversation with your doc and a possible trial at least. You can also see if maybe they have samples, sometimes they can give you a few weeks to see if you'd even react well or not.
Wegovy is so expensive how can people afford it
Remember to eat something otherwise your colon will forget how to work through a no food process. Just an fyi
Good)
👍
The script suggests /only/ fat people are concerned about this medical bias, but I have several friends who are in lower BMI groups who are strong allies.
Note: I self identify as fat. It’s important to let people self identify as fat so we can have these conversations. I don’t have any problem with the availability of interventions and no problem with people choosing not to use those options. If medical bias is the only thing that makes my weight a health risk and I have limited control of those biases it’s a reasonable conclusion to try to lose weight even though that shouldn’t be my responsibility. Obviously other biases can’t be addressed the same way. Racism in medical bias is a massive problem, so even if every fat person could just lose weight it would still be important to find and address medical bias.
right. the bias hurts everyone, but even if it didn't, you don't need to be this tall to enjoy this ride, you can care about people no matter what size you are
I'm all for people losing weight but at $1300 a month there are so many alternatives. I know there are various challenges when losing weight but when you have over a grand to spend I'd rather educate and set up long term habits over a drug unless its insanely effective.
Well, the problem is that almost everyone regains the kg they loose after about a year. There are many many alternatives for loosing weight, but so far there are no good non-surgical methods that have been shown to work long term. And surgery is only an option for those with extreme obesity, since it has its own host of complications.
In terms of an entire population, the only effective methods so far for handling obesity are the ones that focus on prevention. E.g. preventing kids from becoming overweight to begin with, rather than waiting until they are obese adults.
Yeah, a better diet with more fruits and vegetables is a much better approach long term than a medication.
@@lobaxx Self monitoring seems to be the only way, if you weigh yourself every day and adjust you have a much better chance, a good place to start is "fat loss forever" by Layne Norton.
You might want to look into the realities of weight and weight loss, as significant long term weight loss is not an achievable goal for many due to human biology. Hundreds of thousands of years of evolution have designed our bodies to hold onto as much weight as possible to save for times when food is scarce. Short term weight loss is possible, but many gain back more than they lost because the body thinks it's starving and refuses to lose more weight. No amount of diet and education can overcome biological imperatives. It's not an accident that there are no diets that are scientifically proven to work long term.
@@forgotn42 No, that is straight up false, yes the statistics for diets suck but there are those that succeed. I've lost weight and kept it off, and someone who regularly weighs themselves, exercises and educates themselves can do it too.
But mounjaro
Is Way better
Elon musk said he uses Wegovy in his Twitter
Very interesting but its an entire full time salary at walmart lol. Might as well just quit your job at walmart and starve I joke tho.
I use oral semaglutide and it is a game changes, a miracle drug. Yes the dosing takes some forethought but is beyond worth the trouble.
This mind of treatment is not for average weight loss.
This kind of treatment is for severely adipose patients in medical treatment.
Sorry this hormone is produced every time we eat. If we over eat our body becomes desensitized or possibly for other reasons as well we stop producing the hormone or it is reduced and our body stays hungry and our brain never gets a feeling of satiation. So this drug has the hormone or whatever in it that is engineered and last longer than our natural ones would. And we feel full and don’t want to eat.
How about Dr’s teach healthy eating than pushing drugs. Stick with a holistic, natural path Doctors.
I'm imagining all the prepared, flavorful, and healthy food that I could buy with $1300 each month that might result in the same impact as this drug. That should be part of the control group, because anyone wanting that drug should care about a cost-equivalent alternative, not a 2-cent placebo.
This is insane to pay $1300 a month for something that simply “takes away hunger.” Why is it this hard for ppl to just STOP EATING. Eating every 24 hours should be enough...when you eat at Thanksgiving do you really wake up the next day starving hungry?! For $1300 you can just eat 2 grass fed grass finished ribeye steaks with 4 TBS of grass fed Kerrygold butter 1x a day & you won’t be hungry again for 24 hours. High fat carnivore diet like this will cure all kinds of disease & you’ll lose weight & stop being hungry all the time.
@@JC-li8kk Oh, I can answer that one for you. Imagine, for a moment, a day in my life. You wake up, go to the bathroom, and horrible pain grips you before you even get done in the bathroom. Your insides feel like they are being burnt from the inside-out with searing acid. The pain is so bad, it makes you lightheaded and the nausea starts to set in. You know, if you don't eat, you'll soon be writhing in agony on the floor. So, you pick up a light snack, say a glass of orange juice and some fruit puree popsicles and a "stabilizer", in this case a couple of microwavable hashbrowns so the sugar in the popsicles and juice doesn't make things worse. This helps for a few hours, but soon, that searing pain starts to return and you feel very shaky, a sign that, this time, a small "sugar-skimming" snack won't cut it. So you prepare a half of a frozen pizza and some celery (with Caesar vinaigrette dressing... because it's the best salad dressing ever) and more popsicles (without which you won't be able to eat the pizza). Eating helps with the shakiness, but now blood flow has been diverted to the stomach, meaning you'll get horrible side-stabbing cramps that make it very hard to breathe if you don't stay in bed afterward for at least 3 hours, so you take a nap. When you awake, you start this process all over again. Oh, and if you make the mistake of over-exerting yourself making dinner (or, Heaven-forbid, showering or doing household chores, to say nothing of something fun like going for a walk or swimming), then you'll get to enjoy spending days lying in bed while it feels like someone is periodically stabbing your chest with a spear every time your heart beats while you whirl around on the floor of a carousel. -.- Welcome to my life. Sure, I could eat once a day... if I want to spend the next few days in bed in horrid agony. For some strange reason that I can't quite put my finger on, this idea doesn't thrill me.
EDIT: Yes, I *do* realize that I have other health issues in play, and yes, I've gone to doctors/clinics/hospitals (in 7 different US states), had every test imaginable, and they've given practically every diagnosis you can imagine. (Just write a bunch of random conditions down on sheets of paper, stick them in a jar, swirl them around, and pick one at random. That's about how accurate most of the doctors were... and about the same amount of time they spent bothering to try to help, too.) Oh, and, if I was stupid enough to eat your "healthy" grass-fed meat, I'd be writhing and screaming in agony for DAYS on end while it felt like an alien was trying to slowly claw it's way out of my intestines. Been there, done that... far too many times (before we realized why it was happening). Sadly, we are not ALL the same, and many people struggling with obesity are also struggling with a GREAT many other health problems that contribute to their obesity.
@@Quagthistle I did experience a variety of pains when I first started fasting. Especially when I did a 3 day fast. Pains that never showed up when I was eating. Turns out it was my body repairing itself & releasing toxins after years of abuse. I’m thinking most of it was gallbladder, liver, & pancreas. I also have a fatty liver & leaky gut that I’m still trying to heal. I drink a lot of bone broth & kombucha & eat a lot of cocoyo to reset my gut. Now that I know the pain is actually my body healing itself & getting rid of toxins I am able to tolerate it & it gets less painful each time.
If it were that simple, we wouldn't have an obesity problem. You're missing the point. Significant parts of the population have problems controlling their appetite. This product may help them.
@J C It's obvious you're not a doctor or a nutritionist. Why not just hold off on giving medical advice to other people? You should not be so confident in your own level of relevant expertise.
I just need for someone to be next to me at all times to slap the food away.
$1,300 !!!! I’ll just eat less & move more
If that works for you then you'd never be in a position to need it
@@WhichDoctor1 here here. I'm constantly hungry if I eat less. If I eat more though, I make healthy choices. 😋
Instead of talking about weight in the 20th-century lense of being fat is bad. Can you please talk about Intuitive Eating and all the research that backs it?
I mean, that's all well and good if your body is set up in a way that allows it. Trouble is people don't always fit that, there's issues around hormones that regulate that type of thing and not everyone producing the same amount or the brain reading it as well. So for some intuitive eating will be great. For others it'll still mean major over eating but it won't feel like it to the person. And treatments like this could help with that.
@@NethDugan The premise of overeating is largely a myth. It feels like we overeat a) when we are not eating mindfully b) when we are constantly depriving ourselves from our wants.
oof. for $1300/month you could just have a session with a personal trainer every single day for the rest of your life instead
Hopefully if it's so helpful it will become cheaper in the future
It’s frustrating that we have to have medications like this, which would have been unthinkable to our ancestors just a few generations back. By human choice, great effort, and immense financial investment, in the decades following WWII we engineered into existence the obesogenic environment we live in now.
It used to be possible to go your whole life without worrying about becoming overweight. Not anymore. I’m just so disappointed by what a show of utter incompetence the last 80 years have been.
Who is it that you are calling incompetent? What do you mean by "we engineered into existence the obesogenic environment"? These things sound smart, but what do they actually mean?
We have a world where people stopped working on farms decades ago and started working in offices and factories and workshops. Farm productivity simultaneously skyrocketed, leading to cheaper calories for all. The ratio of calories in to calories out went way up. We have many advanced countries with this problem: the UK, Australia, Mexico, Germany. I don't see any "incompetence." I see major changes in history.
I also see correlations between income and education and obesity. Maybe people are more likely to escape obesity because they have the resources and information.
@@gyozakeynsianism Our North American urban design is terrible, obesogenic, environmentally unsustainable, and financially ruinous. It is the result of direct, incompetent, action by us and our governments at every level over the course of 80 years. If you have a free hour, watch this for an introduction: ua-cam.com/play/PLJp5q-R0lZ0_FCUbeVWK6OGLN69ehUTVa.html
It summarizes extensive work by the Strong Towns organization, founded by engineer and urban planner, Charles Marohn, who has spent his career in the service of city governments. There is a lot of additional reading material made available by the organization, with many case studies, that deep dives into details.
We have literally engineered away exercise and now have to engage in dumb hamster-in-a-wheel behaviors like going to the gym just to manage our waistlines. In the process, we’ve also made our social, urban, and natural environments worse.
@@anamandic4540 I agree that we need denser, more walkable cities, for many reasons. But that has little to do with high caloric intake, which is the #1 determinant of obesity. And you haven't addressed the issue of countries with healthier urban layouts that still have obesity, or the fact that better educated, higher income Americans are far less obese. Your pet issue may be related to obesity, but there may be other issues at hand. Using fancy jargon like "obesogenic" doesn't help either.
But you know what might? A medicine that helps control appetite.
Dieting increases all cause mortality. Maintained intentional weight loss is the holy grail of dieting
Best.way.too.lose.weight
Get.out.off.the.car.
And.start.walking
👍