Immunology Fall 2021: Lecture 24 T Cell Activation Part 2

[@gregorykarimian3813]

CTLA-4 binds to CD28 because of higher avidity not affinity. It literally outcompetes by way of more binding sites. This is why CTLA-4 can effectively shut this entire process down.

[@christopherrobinson7541]

Correct.

[@edwingong4710]

Great lecture. But lecture 20 is missing from the list?

[@christopherrobinson7541]

There are two 24's.

[@adrianwoodlock8433]

What are the experiments that show this.