Відео

Thank you Dr. Barker! Very nice lecture!

This has been favorite ever ❤❤❤🎉🎉

SARS2 down regulates MHC1 do you think this could be driving some long covid possibly being chronic infection?

Hey, Grade 12 student here, I've been interested in immunology for a long time now. Are there any books or texts you would recommend? 💗

very educational

As every year, outstanding lectures, thank you!

Brianne, you say here that the only function you care of IgD is that informs about if it just came out from the bone marrow or not. Is not IgD overexpressed when the B cell goes anergic in the periphery due to a lack of the second stimulus? I follow your lectures and the podcast Immune, so I do not know where I get this idea from. Anyway, thanks for making your lectures available to everyone in the world.

I understand how random events can cause the B cells to produce huge variety, but what is the process whereby the antibodies have two identical branches? Also how can dimers and pentamers be produced, with some classes of antibody?

Professor Baker, it seems that Lesson 12 is missing. Would it be possible to upload that lesson? Thank you very much. I enjoy your lectures-they are clear and interesting.

I wish I had of startled this series 3 years ago.

Omg! Thanks 🙏🏼 you

🥰Thank you!

If you have allergic response localized to gut, would that be igA mediated?

Thank you for making these lectures available on UA-cam. I enjoyed watching and learning from them.

Thank you. Great series of lectures. Appreciated.

Thank you so much, Dr . Barker. Super helpful! It would also be great to see what you were writing/drowning on the board

😍

good lecture

Cellular and Molecular Immunology (10th edition)

Thank you Dr. Barker. I am really intrigued by innate immunity. This lecture cannot come at a better time.

Doctor please could you send to me chapter 12

Amazing lecture! Thank you very very much!

Well organized

Can i ask what are textbooks being referred to in these cources? Also there are a couple of playlists for different years on your channel... which one should i watch first?

Thanks a lot for the video

Did I hear correctly you saying that "Viruses don't like the infected cell to express the MHC I"? That first confused me. Why woudn't they want it? After your further explanation I hypothesized that this ribozomal proptein production is "designed" in a way that the cell at the end of it expresses the resulting (or byproduct) protein on the surface. And viruses are, thanks God, not able to hack this proces so that at the end of it is MHC I class protein. Would be nice if it worked sort of like this.

This course is just amazing! thank you Brianne for posting it online! I've binged through all of the lectures in 1 week - I just couldn't stop. (skipped the first lecture due to the sound issues - the rest of the lectures are fine)

Thank you! very informative and clear!

Thank you so much for a great lecture! Very clear explanation!

Great lecture, thank you for posting and making your teaching public 🙏🙏

Thanks a lot, it's so important and helpful

You are the goat.

More comments here tjan any other. Subject..vaccines. not t cells?

Some appreciative comments. Thas nice.

1000 views no comments.

Ok, so ive finally fpund a comment question in ypur lectures. But this video is on b cells not t cells. So techically doesnt count. Ill keep looking.

800 views and no comments. This is concerning. Hi Brianne, I was only told about you today, am shocked and surprised nobody has mentioned you that you have this huge source of educational lectures. I hope people have appreciated your efforts. I'm working on a survey of how people have failed to learn t cells immunology over the last four years. Scientists to FDA in 2022: "don't forget the T cells". Forgotten worriors. Hidden assassin's. Serial killers! It's like everybody HAS forgotten them! You sound very enthusiastic. Im going to sit and work through all your lectures and give you responses you deserve. This is exciting! You sound really friendly too. Wait. Are you one of the TWIV team? I'm sure I recognise your voice.

1000 views and NO comments!?!? We have been in an immunology crisis for 4 years and nobody seems interesting in the most important half of the immune system ??

2.7 thousand views and only 3 comments. All three comments don't talk any science, they only critisice "performance". This is exactly the same response i have had in four years, after thousands of videos. Nobody will discuss the subject with me. Interesting.

4.4 thousand views and no viewers discussing in four years? That's strange.

Hi Brianne again. I'm just going through all your videos and surveying for intelligent communicative responses. This video is 4 years old, 2 thousand views. And only one comment? That seems uncharacteristically low. Almost like the whole world decided to ignore T cells role, and only focused on antibodies?

Hello Brianne. You don't appear to get anyone commenting or asking you questions. Despite t cells immunology being central to COVID and mRNA. I am curious to hear about how you have coped his last four years. Sorry to ask, but have you found people being bizzarly distant, disagreeable, and unresponsive, or uncharacteristically difficult and condescending with you?

Is the thymus also a tertiary lymphoid organ??

I have a question, if C3 spontaneously cleaves and can attach to basically any organic molecule in the body, can it attach to a normal nucleated cell that is displaying an expected peptide on MHC I? Or attach to an MHC II displaying a peptide? If it can then what happens to that cell?

Does an adult normally have circulating CD28+ T-cells outside of infectious state meaning without an obvious acute activation? CD28+ % CD3+ ? Is there a reference as to what would be suspicious and maybe represent an activ antigen presentation?

I really hope I can get your slides🥰

What about the integration of gene repressive markers such as JMJD3-mediated H3K27 as silencing the innate immunity and allowing the transcription of genes with a TH1 linneage signature?

As I interpret Parham figure 9.22, slide 11, it would seem that there may be some fetal IgM being produced, along with maternal IgG. Would we see an increase in fetal IgM concentration if there is an infectious agent present in fetal circulation? Thanks for the great videos!

It doesn't work this trement thay just wont your money becarfeel i have been there done thay thay tookmy money and said thay couldn't be any more for me

This immunotherapy does not work thay just take your money and promise and lie to you that it is a wonder qure for cancer and its not 9 thousand And 5oo$ Dollars in new zealand per trement