My friend likely has drug induced ILD, starting with an ICI drug used in her case to treat NSCLC. The drug was ineffective against the NSCLC so she was given several kinds of chemo subsequently, all of which are associated with drug induced ILD but at a lower frequency than the ICI. We suspect that the subsequent chemos made the ILD worse as though the first ILD sensitized the lungs to the further insults. This drug induction seems to take place over a long time since the use of the drug. Is there a way to detoxify the lungs against further insult (maybe on a drug by drug basis) so that treatment may be more effective? Are any treatments especially effective against drug induced ILD? If long term high dose (tapered) steroids have been ineffective might short term super high dose steroids work? Are there any steroid saving drugs that are effective against drug induced ILD?
Muchas gracias por sus valiosos consejos, yo fui diagnosticada con fibrosis pulmonar. Mi inglés es muy básico.Lo sigo con el traductor automático.
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My friend likely has drug induced ILD, starting with an ICI drug used in her case to treat NSCLC. The drug was ineffective against the NSCLC so she was given several kinds of chemo subsequently, all of which are associated with drug induced ILD but at a lower frequency than the ICI. We suspect that the subsequent chemos made the ILD worse as though the first ILD sensitized the lungs to the further insults. This drug induction seems to take place over a long time since the use of the drug. Is there a way to detoxify the lungs against further insult (maybe on a drug by drug basis) so that treatment may be more effective? Are any treatments especially effective against drug induced ILD? If long term high dose (tapered) steroids have been ineffective might short term super high dose steroids work? Are there any steroid saving drugs that are effective against drug induced ILD?