I have the chek2 mutation and have been diagnosed with advanced prostate cancer at the age of 50. My PSA in July 2020 was 3.5 in July 2021 it was 544 (astronomically high). My Gleason score is 9. My treatments have reduced the PSA from 544 to 8 in 3 months. Your brothers needs to think about prostate cancer too. Hang in there and fight. Try to keep a positive mindset. Its not easy but its all we can do. :^)
I'm 22 ✌🏼 yesterday I was informed that I have the chek2 gene. At the moment I'm going through treatment for thyroid cancer, which was most likely caused by the genetic mutation. Thank you for the information and showing us a hopeful smile
I was also told by 3 medical professionals that chek2 is "rare and unlikely" but still I tested positive. It doesn't matter if it's rare, it still happens to someone.
Samantha I just came upon this; had not seen. Wanted to let you know you look beautiful with no hair. You are radiant in this video. So inspired and proud of you. Such a lovely, strong, brave warrior. Looking forward to seeing Alaska through your eyes. Hugs!!
Omg you’re like definitely 1 in a million now! I’m literally at the hotel to do my genetic testing in the morning...I didn’t even know there was more than brca so you just edumacated me. For real though your attitude about everything is inspiring...love seeing your face!
I have CHEK2; as does my mom (breast cancer at 60), sister, aunt (breast cancer in 60s), and cousin (non-hodgkins lymphoma at ~17 and again ~22). Grandma had what people think was stomach cancer and died at 50. I found my first breast lump in December at 34 and Im freaked out bc I don't think they are really taking me seriously... these gene mutations are for real. Glad to see you are so happy and have such an awesome attitude. You're amazing. Thank you so much for sharing!!
That’s a lot of people! My dad is the only one I know has the mutation in my family. Most people haven’t gotten tested. I hope you find out about your lump soon and I hope it isn’t cancer
@@SamanthaL My MRI was clear. Not all breast lumps are cancer- just like they like to remind us but I'm happy I advocated for screening. I avoided an unnecessary biopsy! I'm cheering for you from the sidelines! Xo. Love your resolve and attitude. You're a bad ass.
I am 22 also, and I am positive for the ATM & NBN genetic mutations which can both cause breast cancer, leukemia, ovarian cancer, and pancreatic cancer. My mom had breast cancer at 29, and I have Chondrosarcoma (bone cancer) currently. My gynecologist found 2 lumps in my right breast, so I’m getting a bilateral breast MRI to see what is going on. I hope you are well 💕
Samantha Lynn the only treatment for chondrosarcoma is surgery. I had my scapula removed earlier this year. Chondrosarcoma is bone and cartilage cancer, and since cartilage is so strong there isn’t a chemo strong enough to break it down and stop cancer growth, so surgery is the only option ♥️ Thank you so much! I will let you know how it goes :)
My uncle got leukemia last year. My dad actually saved him though. He was his blood donor and I’m so happy he’s alive. I hope you’re okay 👍 ❤️ (Dad’s account)
Never knew smokers always got breast cancer. My late husband's family was riddled with the Muir Torre gene. Those with it died young and those without it lived into their 90s. I've been retired now from medicine for some years, but I always thought that many conditions will be found to have a genetic basis - and with increasing knowledge this is being shown. I do admire Samantha and her coping with such a cruel disease at so very young an age.
Smoking just increases the risk. I agree with you since having a family history of cancer is a big risk factor and families have genetic similarities. It’s crazy how much in genetics is still unknown
Hi Samantha my name is Kaitlin I just wanted to quickly write a comment and say that I can definitely relate to your story with a rare genetic mutation. I discovered when I was 25 years old that I had a PTEN Mutation, then I was diagnosed with breast cancer right after that.
I have both CHEK2 and BRIP1 gene mutations. Almost 0 history of any cancer in my family, I was diagnosed with breast cancer at 40 years old. I just turned 47 and fear of recurrence is strong. I am scanned every six months alternating between diagnostic mammograms and breast MRIs. Also started having colonoscopies and they have removed pre-cancerous polyps every time. 😔
I have the CHEK-2 gene mutation too and got breast cancer at age 39. Still having chemo right now. The rest of the family will have to get tested too now.
Samantha I admire you so much you give me hope, so last year in Sept we found my mom had breast cancer within weeks had surgery then she had the gene test came out my mom did have that CHEK2 gene also.Once that was done my sister and I had the test done too we were told since there was 2 of us there was a 50% change that either my sister or myself had it, results came back last Nov. Come to find out I also have that gene CHEK2...I know at least for my family case cancer is definitely the rereasom from that gene which sucks ,but I'll leave it in God's hands he has control now.
I'm still waiting for my genetic results. I'll bet I have no evidence of genetic mutations that code for Cancer. This topic is fascinating to me. For example, CHEK2 is itself a mutation of the BRACA2 mutation. Interesting stuff! The study of these mutations will fine-tune targeted therapy. I dream that in the future, targeted therapy will replace chemo.
I also have a rare gene mutation called Lynch Syndrome. I am PMS2 positive. We have such a high risk of cancer, it's a lot scary. We had a 50/50 chance of Mt kids having the mutation as well. My oldest has it and so does my sister. Its overwhelming and scary all the time. I'm at the doctor all the time. Now facing a potential cancer scare too. I am hoping against hope my youngest does not have it. Genetics are fun.
I have been watching your videos non stop. I listen to them at work too. Not a stalker. I just love the way you explain things. It helps me not be scared as often. You are quite the young woman. I wish nothing but the very best life has to offer, and then some.
I don’t have the gene mutation (or I’m pretty certain I don’t...) but I’d still like to be best friends. Also, for your future colonoscopy, I highly recommend seeing if you can get the laxative pill thing instead of that nasty gallon of liquid crap because it will make that procedure much more pleasant.
Agreed. I have Chek2 mutation too with a family history of colon cancer starting at 29... So I've started my colonoscopy journey. The Docalax/Miralax in Gatorade wasn't too bad. I've been told that the chalky stuff can make ya vomit.
I did the whole gene test in 2017 when I was diagnosed of breast cancer. It came back all negative, but my sister has breast and uterine cancer and I lost my brother to testicular cancer at a young age.
I have stage 2 grade 3 triple negative breast and I am BRACCA negative as well as negative for other genetics except for the AXIN2 gene and it was VUS (variant of uncertain significance) so for me they said it was rare for me as well but with this gene it’s usually nothing to be worried about. But me having triple negative breast cancer and nit BRACCA positive was as if I got breast cancer when I wasn’t suppose to.
I too was a young person to get Stage 4 Ovarian cancer at 38 which my doctors considered a young age to get that diagnosis. I found out at with that diagnosis I have BRCA-1 gene so I cried and cried because I had two young children at 38 a son 18 mos. old and a 4 year old daughter. I was so saddened to know this gene could be passed onto them. I am adopted so my family history starts with me. It sucks there is not much information on CHEK2 but any new information can be learned by our doctors is a good thing overall for the cancer community. I believe God chose us so that others can learn from our cancer journeys along with all who love us and support us. I love your attitude as I have the same one 😃 take care and will continue to pray for you kiddo
hi my name is Adrianna Anzaldua I was diagnosed with stage 3 Ovarian cancer. I just discovered I have the CHEK2 mutation as well. I’m in remission right now but know nothing about what’s going to happen next since I have the mutation. I’d like to ask what have your doctors told you since you have the mutation? Does that mean more scans and check ups more often?
Does anybody have Invasive Lobular Cancer and CHEK2 mutation...As it stands the Oncologist suggested that after the radiotherapy starting next week I have choice of following chemotherapies : • 4 cycles of taxotere/cyclophosphamide given the node negative lobular component or • 6 cycles of carboplatin/docetaxel given the CHEK2 mutation. Choice is for me???
You never know it could be the gene my wife is BRCA 1 positive that came from her mom side all the girls test positive for the gene only her aunt had breast cancer but fast forward 40 years to now and my wife and her sister got it at 29 and 30 her mom and aunts are in their 50s and still have not gotten cancer. Cancer sucks stay positive god is good
My doctor told me it wasn’t rare, about 1/10 have it. That’s not rare if she is correct. However knowing you have it, there’s nothing they can do. It’s not like they have any credible dietary advice, just keep eating the SAD diet, and we will see you again in six months. It’s useless to know, Ai was already on schedule for more testing. DNA is not the source of cancer, insulin resistance is, but they have no interest in advising anyone to eat a keto diet. They can put defective DNA into a healthy cell, nothing happens. But when they put in defective mitochondria, it goes to cancer every time. It has NOTHING to do with the DOGMA that permeates medicine, which is profit based.
That is not correct. It is possible that 1 in 10 people diagnosed with breast cancer have some sort of mutation associated with an increased risk. But that’s not 1 in 10 in the whole population and like I said, that is ANY mutation associated with an increased risk of breast cancer. This specific mutation is rare
I am so sorry to see an young and energetic person like you falling sick. Have you considered healthy low carb real food diet, lots of raw foods, lots of greens(not just few leafs in salad, Proper cooked greens like curry), zero processed foods(anything you buy in a packet), very low/zero animal protein(your body needs to recycle itself, google autophagy) , Zero sugar including diet coke etc, cooking with healthy non refined organic oils (coconut or olive oil), lot of sunshine(check your vitamin D levels, this is most important), frequent grounding(like baths in sea, sitting on grass, bush walk in national parks), lots of sleep following sun, lots of vitamin C, lots of probiotic and prebiotic foods and Rick Simpson oil. I am sure you will get out of this difficult phase and lead a normal life.
Harish a. Hate to rain on your parade, but vegans get cancer too. Would people stop giving cancer patients advice-it is incredibly tactless & annoying. Keep in mind, before the TB bacillus was identified, people ascribed the disease to life style choices, etc. Obviously, people do their best to stay healthy, but cancer can hit anyone for a multitude of reasons.
I have the chek2 mutation and have been diagnosed with advanced prostate cancer at the age of 50. My PSA in July 2020 was 3.5 in July 2021 it was 544 (astronomically high). My Gleason score is 9. My treatments have reduced the PSA from 544 to 8 in 3 months. Your brothers needs to think about prostate cancer too. Hang in there and fight. Try to keep a positive mindset. Its not easy but its all we can do. :^)
I'm 22 ✌🏼 yesterday I was informed that I have the chek2 gene. At the moment I'm going through treatment for thyroid cancer, which was most likely caused by the genetic mutation. Thank you for the information and showing us a hopeful smile
I Hope you’re doing better ❤
I was also told by 3 medical professionals that chek2 is "rare and unlikely" but still I tested positive. It doesn't matter if it's rare, it still happens to someone.
Please don’t think that youre not being helpful because you are sooo educating all of us and your spirit and energy is so amazing to watch💖
Glad you like it, thanks!
Samantha I just came upon this; had not seen. Wanted to let you know you look beautiful with no hair. You are radiant in this video. So inspired and proud of you. Such a lovely, strong, brave warrior. Looking forward to seeing Alaska through your eyes. Hugs!!
aw thank you :)
Omg you’re like definitely 1 in a million now! I’m literally at the hotel to do my genetic testing in the morning...I didn’t even know there was more than brca so you just edumacated me. For real though your attitude about everything is inspiring...love seeing your face!
Aw thank you! I hope your tests go well :)
I have CHEK2; as does my mom (breast cancer at 60), sister, aunt (breast cancer in 60s), and cousin (non-hodgkins lymphoma at ~17 and again ~22). Grandma had what people think was stomach cancer and died at 50. I found my first breast lump in December at 34 and Im freaked out bc I don't think they are really taking me seriously... these gene mutations are for real. Glad to see you are so happy and have such an awesome attitude. You're amazing. Thank you so much for sharing!!
That’s a lot of people! My dad is the only one I know has the mutation in my family. Most people haven’t gotten tested. I hope you find out about your lump soon and I hope it isn’t cancer
@@SamanthaL My MRI was clear. Not all breast lumps are cancer- just like they like to remind us but I'm happy I advocated for screening. I avoided an unnecessary biopsy! I'm cheering for you from the sidelines! Xo. Love your resolve and attitude. You're a bad ass.
@@elainekommenge1157 that's great! Happy for you :)
I am 22 also, and I am positive for the ATM & NBN genetic mutations which can both cause breast cancer, leukemia, ovarian cancer, and pancreatic cancer. My mom had breast cancer at 29, and I have Chondrosarcoma (bone cancer) currently. My gynecologist found 2 lumps in my right breast, so I’m getting a bilateral breast MRI to see what is going on. I hope you are well 💕
Are you going through treatment now? Also let me know how your MRI goes. Hope it’s nothing serious
Samantha Lynn the only treatment for chondrosarcoma is surgery. I had my scapula removed earlier this year. Chondrosarcoma is bone and cartilage cancer, and since cartilage is so strong there isn’t a chemo strong enough to break it down and stop cancer growth, so surgery is the only option ♥️ Thank you so much! I will let you know how it goes :)
My uncle got leukemia last year. My dad actually saved him though. He was his blood donor and I’m so happy he’s alive. I hope you’re okay 👍 ❤️ (Dad’s account)
Never knew smokers always got breast cancer. My late husband's family was riddled with the Muir Torre gene. Those with it died young and those without it lived into their 90s. I've been retired now from medicine for some years, but I always thought that many conditions will be found to have a genetic basis - and with increasing knowledge this is being shown. I do admire Samantha and her coping with such a cruel disease at so very young an age.
Smoking just increases the risk. I agree with you since having a family history of cancer is a big risk factor and families have genetic similarities. It’s crazy how much in genetics is still unknown
Hi Samantha my name is Kaitlin I just wanted to quickly write a comment and say that I can definitely relate to your story with a rare genetic mutation. I discovered when I was 25 years old that I had a PTEN Mutation, then I was diagnosed with breast cancer right after that.
Hi Kaitlin, thanks for the comment! Hope you are doing well ❤️
That's really interesting to hear. Thx so much for sharing. You're explaining so well and clearly.
Glad you enjoyed! Thanks for watching
You're amazing Samantha, on so many different levels!
:) thank you
I have both CHEK2 and BRIP1 gene mutations. Almost 0 history of any cancer in my family, I was diagnosed with breast cancer at 40 years old. I just turned 47 and fear of recurrence is strong. I am scanned every six months alternating between diagnostic mammograms and breast MRIs. Also started having colonoscopies and they have removed pre-cancerous polyps every time. 😔
I have the CHEK-2 gene mutation too and got breast cancer at age 39. Still having chemo right now. The rest of the family will have to get tested too now.
Your blue eyes and blue shirt are pretty. Never heard of this gene. Interesting and very informative.💕
Thank you!
Samantha I admire you so much you give me hope, so last year in Sept we found my mom had breast cancer within weeks had surgery then she had the gene test came out my mom did have that CHEK2 gene also.Once that was done my sister and I had the test done too we were told since there was 2 of us there was a 50% change that either my sister or myself had it, results came back last Nov. Come to find out I also have that gene CHEK2...I know at least for my family case cancer is definitely the rereasom from that gene which sucks ,but I'll leave it in God's hands he has control now.
I'm sorry to hear that. Hope your mom and family are doing well
My mom had the chek2 mutation. I’m going to be getting genetic testing soon ❤️
I am having the full blast of chek 2. Within 2 years 1 cancer and recurrence. Once it start it is a beast. 4 surgery later still in it.
Hello I also have the check 2 mutation and also so confused with all of it!! Good luck in your journey
Who knew!?! I know I didn’t! But I do now thanks to you! 💞
I have the CHEK 2 mutation! I'm 25 and just got diagnosed a couple months ago.
Thank you this is my 2nd round with cancer and I just got told yesterday I have this
My children are nervous
I'm still waiting for my genetic results. I'll bet I have no evidence of genetic mutations that code for Cancer. This topic is fascinating to me. For example, CHEK2 is itself a mutation of the BRACA2 mutation. Interesting stuff! The study of these mutations will fine-tune targeted therapy. I dream that in the future, targeted therapy will replace chemo.
I also have a rare gene mutation called Lynch Syndrome. I am PMS2 positive. We have such a high risk of cancer, it's a lot scary. We had a 50/50 chance of Mt kids having the mutation as well. My oldest has it and so does my sister. Its overwhelming and scary all the time. I'm at the doctor all the time. Now facing a potential cancer scare too. I am hoping against hope my youngest does not have it. Genetics are fun.
So sorry to hear about that. Hope everything turns out ok
I have been watching your videos non stop. I listen to them at work too. Not a stalker. I just love the way you explain things. It helps me not be scared as often. You are quite the young woman. I wish nothing but the very best life has to offer, and then some.
I don’t have the gene mutation (or I’m pretty certain I don’t...) but I’d still like to be best friends.
Also, for your future colonoscopy, I highly recommend seeing if you can get the laxative pill thing instead of that nasty gallon of liquid crap because it will make that procedure much more pleasant.
Yeah! Let's be best friends! Haha, I'll try to remember that
Agreed. I have Chek2 mutation too with a family history of colon cancer starting at 29... So I've started my colonoscopy journey. The Docalax/Miralax in Gatorade wasn't too bad. I've been told that the chalky stuff can make ya vomit.
I did the whole gene test in 2017 when I was diagnosed of breast cancer. It came back all negative, but my sister has breast and uterine cancer and I lost my brother to testicular cancer at a young age.
😢😢😢
I have stage 2 grade 3 triple negative breast and I am BRACCA negative as well as negative for other genetics except for the AXIN2 gene and it was VUS (variant of uncertain significance) so for me they said it was rare for me as well but with this gene it’s usually nothing to be worried about. But me having triple negative breast cancer and nit BRACCA positive was as if I got breast cancer when I wasn’t suppose to.
I too was a young person to get Stage 4 Ovarian cancer at 38 which my doctors considered a young age to get that diagnosis. I found out at with that diagnosis I have BRCA-1 gene so I cried and cried because I had two young children at 38 a son 18 mos. old and a 4 year old daughter. I was so saddened to know this gene could be passed onto them. I am adopted so my family history starts with me. It sucks there is not much information on CHEK2 but any new information can be learned by our doctors is a good thing overall for the cancer community. I believe God chose us so that others can learn from our cancer journeys along with all who love us and support us. I love your attitude as I have the same one 😃 take care and will continue to pray for you kiddo
Thank you for sharing this! Hope you are doing ok
hi my name is Adrianna Anzaldua I was diagnosed with stage 3 Ovarian cancer. I just discovered I have the CHEK2 mutation as well. I’m in remission right now but know nothing about what’s going to happen next since I have the mutation. I’d like to ask what have your doctors told you since you have the mutation? Does that mean more scans and check ups more often?
I also was tested positive for Chek2. I do not have cancer but my doctor wants me to get a mastectomy
I recently was diagnosed with chek2 this week 😢
Also have chek2 dx with Primary Myelofibrosis, blood/marrow cancer.
I have chek2. And found a lump. Going for biopsy consult.
Hope everything comes back ok!
I have CHEK 2... Just had complete double mastectomy. I have a 28 year old daughter. There's nothing worse than thinking I may have passed it to her.
Hoping your daughter doesn't have it and hope your recovery goes well!
IM FROM MALAYSIA...NICE TO MEET YOU ALL AND NICE VID👍
Thank you
Does anybody have Invasive Lobular Cancer and CHEK2 mutation...As it stands the Oncologist suggested that after the radiotherapy starting next week I have choice of following chemotherapies :
• 4 cycles of taxotere/cyclophosphamide given the node negative lobular component or
• 6 cycles of carboplatin/docetaxel given the CHEK2 mutation.
Choice is for me???
Hi, what you choose? Can tell me please size of tumor? Thank you
I got it girl, just found out.
Mastectomy 2024
Sending u love and lots of good juju.
Very informative
Thanks
I lost my grampa to cancer cuz he smoked then the cancer cote up to him. he quite smoking but cancer still got him
I'm so sorry for your loss
@@SamanthaL thank you, Cancer sucks. I also maby kidney failure
I had heard of this but my genetic councilor had mentioned never having met someone with it, I have the BRCA2 mutation
you have a great personality, funny, but mostly your upbeat a d upbeat beats down cancer.
Hi,
What variant of chek2 mutation dod you have ?
c.433C>T
Just got back from the hospital, CHEK2 mutation here, high five! How are you doing today ?
lol high five! I'm doing great! Currently no evidence of disease :)
I have the mthfr mutation and i started mammograms at 35
Is it triple negative breast cancer?
No hormone receptor positive, HER2 negative. I have another video on my channel about the specifics
You never know it could be the gene my wife is BRCA 1 positive that came from her mom side all the girls test positive for the gene only her aunt had breast cancer but fast forward 40 years to now and my wife and her sister got it at 29 and 30 her mom and aunts are in their 50s and still have not gotten cancer. Cancer sucks stay positive god is good
Very true. There's no way of knowing
My doctor told me it wasn’t rare, about 1/10 have it. That’s not rare if she is correct. However knowing you have it, there’s nothing they can do. It’s not like they have any credible dietary advice, just keep eating the SAD diet, and we will see you again in six months. It’s useless to know, Ai was already on schedule for more testing. DNA is not the source of cancer, insulin resistance is, but they have no interest in advising anyone to eat a keto diet. They can put defective DNA into a healthy cell, nothing happens. But when they put in defective mitochondria, it goes to cancer every time. It has NOTHING to do with the DOGMA that permeates medicine, which is profit based.
That is not correct. It is possible that 1 in 10 people diagnosed with breast cancer have some sort of mutation associated with an increased risk. But that’s not 1 in 10 in the whole population and like I said, that is ANY mutation associated with an increased risk of breast cancer. This specific mutation is rare
I am so sorry to see an young and energetic person like you falling sick.
Have you considered healthy low carb real food diet, lots of raw foods, lots of greens(not just few leafs in salad, Proper cooked greens like curry), zero processed foods(anything you buy in a packet), very low/zero animal protein(your body needs to recycle itself, google autophagy) , Zero sugar including diet coke etc, cooking with healthy non refined organic oils (coconut or olive oil), lot of sunshine(check your vitamin D levels, this is most important), frequent grounding(like baths in sea, sitting on grass, bush walk in national parks), lots of sleep following sun, lots of vitamin C, lots of probiotic and prebiotic foods and Rick Simpson oil. I am sure you will get out of this difficult phase and lead a normal life.
No, I really like sugar. Thanks though :)
Harish a. Hate to rain on your parade, but vegans get cancer too. Would people stop giving cancer patients advice-it is incredibly tactless & annoying. Keep in mind, before the TB bacillus was identified, people ascribed the disease to life style choices, etc. Obviously, people do their best to stay healthy, but cancer can hit anyone for a multitude of reasons.
I’m having my 3rd colonoscopy at 38 next month. Ugh 😫🤪
Hope it goes well!
I have it!
💖💖💖💖xx
I’m wondering did you ever care of your cell phone like in your bra and maybe that caused it?
No, I have never done that
Hej can I contact with you on private?