Thank you SOOO much for all your hard work in putting together these videos. Your clinical medicine series videos have been by far the most helpful resource for me for studying for Step 2. We love you!!!
I have secondary adrenal insufficiency, caused by Pembrolizumab (Keytruda) immunotherapy. I see several new people every week joining the support groups online who have this side effect of immunotherapy, I think it’s becoming more and more common. I have almost no cortisol, almost no acth, and almost no DHEA. I also have almost no estrone, estradiol, estriol, progesterone, or pregnenolone. I have high FSH and FH. I was not in menopause prior to chemotherapy & immunotherapy.
I've just had a low morning cortisol test and I'm awaiting a hospital appointment. I feel absolutely dreadful, the worst headaches and some very strange muscle fasciculations all over my body plus hypoglycemia attacks that cause my whole body to tremor. The fatigue......it's just awful, takes me hours to get up then I'm done again mid afternoon. Thank you for this video, very helpful.
@@fauxpro4561 I failed at the first hurdle. Endocrinology discharged me because I don't have Addisons, they clearly don't understand secondary adrenal insufficiency 😕 back feeling exactly the same and no treatment 😕
Our kids asthma specialist had us put a humidifier inside their room which we later learned contributed to mold and dust mite growth, making their asthma chronic. He also prescribed FLOVENT, a steroid inhaler at a dose 4x what it should be for our tiny daughter and it shut down her adrenal system, she nearly died in ICU before an endocrinologist figured out the cause and treatment (cortisone helped her recover over 6 months until she was ok again). This doctor should be behind bars, but he's out doing it to thousands of other kids with the full support and profit of pharma. This system is not helping us. We got our kids off of the inhalers, removed the humidifier and they've been fine since. I'm not diagnosing other's conditions or situations but I'm a parent who nearly lost my child due to gross misuse of these drugs on my daughter.
Time 16:47 what if a pregnant mother does not have any pituitary/ adrenal/ endocrine issues before or during pregnancy… what would you guess would cause the new born to be diagnosed with hypopituitary?
How can my mother have Secondary and a tumor and I also have Secondary (looking for a tumor)? Is this genetic? I have been in Addison crisis. If I can tell you guys it is AWFUL for the patient... Multiply awful x 1,000,000. INTENSE headache, vomiting, more intense headache, lots of urination, drink water, urinate it back out... Then, you just want to lie down and go to sleep. Luckily (I didn't know I had Addisons), I called a friend and told him I was dying. I didn´t know I was dying but it felt like dying. They called 9'11. You should know that intense crying and greiving sends me into Addisons Crisis. I don´t know if this is true for other patients. I was out of the country. I am very surprised the abulance knew to give me steroids.
Hi Zack, love your topics. Here's one for you. My SIL is in hospital due to UTI, Adrenal insufficient. Not able to walk & speech weak. Now back in 2014, she was diagnosed diagnosed with a malignant Adrenal gland plus kidney. No chemo or radiation. Years go by, now has Breast cancer, did some radiation. Then few years later has lesions in lungs. Has gone thru chemo(don't know type) & I believe radiation too. Became very sick due to gastritis from chemo tablets & UTI. ANY ideas!!
Is there any difference between prednisone and prednisolone? I usually only see medical literature favoring prednisolone as a hydrocortisone alternative in certain situations.
I was recently diagnosed with Secondary Adrenal Insufficiency, but my MRI results came back normal. I have no history of long-term steroid use, and none of the typical explanations for Secondary AI seem to apply in my case. I've been informed that my condition is idiopathic. Could you please advise on what additional tests I can do to determine why my pituitary gland isn't functioning properly despite the normal MRI results?
Today I have received my Acth and cortisol blood test and both are high. I also have celiac, hypothyroidism, pernicious anemia and autoimmune gastritis. Since acth and cortisol are both high, I am not taking in consideration Cushing syndrome sknce i do not have metabolic syndrome and my fasting glucose/insulin are perfects. Aps 2 has diabetes mellitus 1, does it also have celiac since it share the same genetic ?
In CAH there is deficiency of 21-OH enzyme which cause decrease in aldosterone and cortisol and switch the pathway more towards the synthesis of androgen
Some people were just born to teach, thank you professor Zach!
Wait a minute, you apologised a few days ago for this masterpiece???!!!
You smashed medicine , you monster ❤️❤️🔥🔥🔥🔥🔥💪💪💪💪💪
I SWEAR MY PROFESSOR COULD'VE JUST PLAYED THIS! i sat there for 2H n understood nothing but Zack in 51 mins made it all click
Yesssss 👍👍👍
What I learnt in medicine is: “Mute doctors and listen to Zack”
I have Addison's Disease and love that you covered this !
Thank you so much for covering this. Diagnosed with secondary adrenal insufficiency from a TBI, this video helped me understand my condition better.
literally the best teacher
Thanks!
Thank you SOOO much for all your hard work in putting together these videos. Your clinical medicine series videos have been by far the most helpful resource for me for studying for Step 2. We love you!!!
Best teacher in the world ❤❤❤
Thank you very much. You're the best! Please, keep making these amazing lectures. We desperately need them
I have secondary adrenal insufficiency, caused by Pembrolizumab (Keytruda) immunotherapy. I see several new people every week joining the support groups online who have this side effect of immunotherapy, I think it’s becoming more and more common. I have almost no cortisol, almost no acth, and almost no DHEA. I also have almost no estrone, estradiol, estriol, progesterone, or pregnenolone. I have high FSH and FH. I was not in menopause prior to chemotherapy & immunotherapy.
I also have secondary adrenal insufficiency from Pembrolizumab ( Keytruda ) immunotherapy
SAI here. Very helpful.
Thanks alot❤ from India🇮🇳
Outdone yourself with this one 👏🏻
You are always my go to channel. Thank you
Thank you for the amazing video!!
I have never been disappointed since I started watching❤❤
your videos carry me through my advanced physiology class!
Explicação maravilhosa! E muito obrigada por acrescentar legendas em português! ❤️
Great video, thanks Ninja Nerd!
Thank you for this video
Thank You very much for all the work, time, and execution of these very informative videos!! 👏🏼 👏🏼
I've just had a low morning cortisol test and I'm awaiting a hospital appointment. I feel absolutely dreadful, the worst headaches and some very strange muscle fasciculations all over my body plus hypoglycemia attacks that cause my whole body to tremor. The fatigue......it's just awful, takes me hours to get up then I'm done again mid afternoon. Thank you for this video, very helpful.
How did you get on? I'm in a similar boat currently... Recent blood test showing low morning cortisol
@@fauxpro4561 I failed at the first hurdle. Endocrinology discharged me because I don't have Addisons, they clearly don't understand secondary adrenal insufficiency 😕 back feeling exactly the same and no treatment 😕
@@kellyofthehead It's well worth seeing one privately if you're still suffering
PERFECT. PERFECTION.
best teacher ever !
I love your teaching methodologies.
Excellency at its best❤
You are great. Thank you for sharing yor knowledge.
You are AMAZING!! Thank you so much!!
Excellent work as always
Thank you for the videos
Thank you so much ❤❤, very helpful
Thank You for wonderful lessons!
Amazing lecture as always. Ty Zach!
Wow!!! Agreed this is a masterpiece presentation!!!👏😊
Sounds like your explanation fits some dysautonomia/ pots syndrome symptoms
Thank you Zach!
From Yemen, big thanks
U r amazing teacher .. love and respect 🙏🙏❤️
Our kids asthma specialist had us put a humidifier inside their room which we later learned contributed to mold and dust mite growth, making their asthma chronic. He also prescribed FLOVENT, a steroid inhaler at a dose 4x what it should be for our tiny daughter and it shut down her adrenal system, she nearly died in ICU before an endocrinologist figured out the cause and treatment (cortisone helped her recover over 6 months until she was ok again). This doctor should be behind bars, but he's out doing it to thousands of other kids with the full support and profit of pharma. This system is not helping us. We got our kids off of the inhalers, removed the humidifier and they've been fine since.
I'm not diagnosing other's conditions or situations but I'm a parent who nearly lost my child due to gross misuse of these drugs on my daughter.
Please do not stop spreading your message .
It’s relevant in all areas of health and medicine .
Hope she gets well soon !
get the papers and sue them !!
you will save hundreds of lives
Time 16:47 what if a pregnant mother does not have any pituitary/ adrenal/ endocrine issues before or during pregnancy… what would you guess would cause the new born to be diagnosed with hypopituitary?
Great and excellent ❤
Thank you so much, Jarur, Murshidabad WB India🇮🇳.
Thank you 💗
Very helpful thanks a lot
brother is back putting all my medical professors in university in shambles.
thank you 👑
Thank you very much ❤
Thank you very much
Thank you!
very interesting.
Thankyou Zach❤
How can my mother have Secondary and a tumor and I also have Secondary (looking for a tumor)? Is this genetic?
I have been in Addison crisis. If I can tell you guys it is AWFUL for the patient... Multiply awful x 1,000,000. INTENSE headache, vomiting, more intense headache, lots of urination, drink water, urinate it back out... Then, you just want to lie down and go to sleep. Luckily (I didn't know I had Addisons), I called a friend and told him I was dying. I didn´t know I was dying but it felt like dying. They called 9'11. You should know that intense crying and greiving sends me into Addisons Crisis. I don´t know if this is true for other patients. I was out of the country. I am very surprised the abulance knew to give me steroids.
Thank you
Hi Zack, love your topics.
Here's one for you. My SIL is in hospital due to UTI, Adrenal insufficient. Not able to walk & speech weak. Now back in 2014, she was diagnosed diagnosed with a malignant Adrenal gland plus kidney. No chemo or radiation. Years go by, now has Breast cancer, did some radiation. Then few years later has lesions in lungs. Has gone thru chemo(don't know type) & I believe radiation too.
Became very sick due to gastritis from chemo tablets & UTI. ANY ideas!!
Excellent
thank you!
Thank you sir
Is there any difference between prednisone and prednisolone? I usually only see medical literature favoring prednisolone as a hydrocortisone alternative in certain situations.
My professor could never
You are amazing❤️
Anterior pituitary back at it again
Sir amazing love you from Pakistan ❤❤❤❤❤.
Thanks
What about hidradenitis suppurativa
I was recently diagnosed with Secondary Adrenal Insufficiency, but my MRI results came back normal. I have no history of long-term steroid use, and none of the typical explanations for Secondary AI seem to apply in my case. I've been informed that my condition is idiopathic. Could you please advise on what additional tests I can do to determine why my pituitary gland isn't functioning properly despite the normal MRI results?
You are amazing
Today I have received my Acth and cortisol blood test and both are high.
I also have celiac, hypothyroidism, pernicious anemia and autoimmune gastritis.
Since acth and cortisol are both high, I am not taking in consideration Cushing syndrome sknce i do not have metabolic syndrome and my fasting glucose/insulin are perfects.
Aps 2 has diabetes mellitus 1, does it also have celiac since it share the same genetic ?
Which of these adrenal components causes blood sodium to drop?
Why do I maintain a normal blood sugar when untreated for SAI if cortisol causes blood sugar to rise and my cortisol tanked?
Can you just tell me why just alpha 1 sensitivity increases why not beta 1 & 2 ?????????
zach explain it like drinking water
Thank you
Eosinophilia? Why would that be the case? And how high?
Awesome
Love u zackk❤❤
Are there any other microbes that infect and deteriorate the adrenals? Never-ending. You answered.
You rock
da best
why isnt CAH considered primary adrenal insufficiency?
CEA is because of congenital absence of 21OH and manifested in young children.....
CAH*
In CAH there is deficiency of 21-OH enzyme which cause decrease in aldosterone and cortisol and switch the pathway more towards the synthesis of androgen
CRH isnt decreased in secondary, its increased (just to avoid confusion)
phenom vids brother
Elaborate
I have an upcoming SOAP note on anadrenal crisis case, without you my ass is grass 😭
🔥🔥🔥
28:29
❤❤❤
Yo I ❤
My comment❤
❤
6 th like sir, I'm pratheesh from india ( Tamil Nadu).am big fan of you sir.say one hi sir.
🎉🎉🎉🎉
💯🥷💯🥷💯🥷💯
ninja nerd dislikes 2 things, OCD and spelling lol
You are AMAZING!! Thank you so much!!
Thank you so much ❤
Thankyou sooo much for this
Thanks
❤❤❤
❤
Thank you so much