What Are Clinical Trial Phases?

Watch to learn about the three main phases of clinical trials. Clinical trials are research studies that involve people. Understanding what they are can help you decide if a clinical trial might be an option for you or a loved one.
_______________________________________
For more on clinical trials, visit: www.cancer.gov/clinicaltrials
To find NCI-supported clinical trials, go to: trials.cancer.gov
Need help finding a trial? Have a cancer-related question? Call, e-mail, or write the NCI Contact Center at: www.cancer.gov/contact
_______________________________________
Clinical trials are research studies that involve people. Most clinical trials to test new cancer treatments are done in a series of steps, called phases. If a new treatment is successful in one phase it moves to the next phase. Let's take a look at the three main phases of clinical trials. Phase 1 trials are small enrolling less than thirty patients. Phase 1 trials are designed to find a safe dose of the new treatment, determine how the treatment should be given, and learn how it affects the body. If a safe doses found the new treatment goes to phase 2 testing. More patients are enrolled, usually 100 or less. Phase 2 trials study have the treatment effects the body, and how the treatment works for a certain type of cancer. If a new treatment is found to be safe and have some benefit, it goes to phase 3. This is when many participants are needed, usually more than 100 and sometimes thousands. Phase 3 trials compared the new treatment with the current treatment to see which one is better. One thing is certain with any phase trial, by taking part you will help future patients by helping today's scientists learn more about cancer. For more information about clinical trials, including their possible risks and benefits for you go, to cancer.gov/clinicaltrials

[@rvstats_ES]

Short but very informative video. Thanks

[@AlexiesB]

so nice infographics, and informative.

[@dr.satyabratasahoo5644]

Marvellous

[@angeladaye1885]

Already have a trial since 1977

[@azariahlawrence5005]

Who did the info graphics? Great job and would like to enlist their services

[@NCIgov]

Hi Azariah, You can contact the NCI Public Inquiries staff for assistance with your question. They can be reached at [e-mail]. Take care.

[@Heresheis0818]

Less
Is
more
#Respect every day as days do count 😢

[@bluesdirt5889]

Are all phases double blind ?

[@NCIgov]

Not all trials use blinding. In some phase 2 and all phase 3 clinical trials, patients are assigned to groups that receive different treatments and may be single or double-blinded. You can read more about randomization and blinding at www.cancer.gov/about-cancer/treatment/clinical-trials/what-are-trials/randomization. The following link provides more information about clinical trial phases: www.cancer.gov/about-cancer/treatment/clinical-trials/what-are-trials/phases.

[@ProfRoofs]

So who do you think will develop their most effective coronavirus vaccine?

[@NCIgov]

The NCI, a component of the National Institutes of Health (NIH), is the nation's principal agency for cancer research. While the NCI is actively involved in researching COVID-19, the National Institute of Allergy and Infectious Diseases (NIAID) is the primary NIH organization for COVID-19 research. Contact information for NIAID may be found at www.niaid.nih.gov/global/contact-us. Take care.