Starting in 2011, I had severe spells of nausea, vomiting, and passing out that would come on suddenly and randomly after eating. It started with once a month in my 30s then after a few years these episodes could be 1-3 times a week and basically shut me down for 1-2 days. Id wake up with full body tingling like I was being hit with a cattle prod. After finding out that I have the MTHFR TT and MTRR AA (ironically from Rhonda's genetic services), I started taking a methylated B-complex, methylfolate, and alot of methyl b12. Results after just a few days -- 100% my symptoms were gone and that was over a year ago with no relapse. This information and vitamin therapy literally saved my life as I was becoming terrified to eat yet my doctors couldn't find anything. Cant stress enough how debilitating these episodes were and how radically different my life is once I gave my body what it needed to survive.
Your information is changing my life. I am so motivated to eat healthier and watch my micronutrients. I first heard you on The Joe Rogan Experience and I'm so glad you have your own channel! Thank you for providing us with all this information, you're definitely making an impact!
@@snubdawg1386 your response speaks of *YOUR* experiences with college, not Jovanka’s, and you will already know there’s a tremendous variation in quality of education. I’m fully agreeing with @Jovanka Ciares, this channel is excellent.
@@PhilWhelanNow i have no experience with college ....after i learned how to write, read and do basic math i was done with the school system.... i'm only repeating what i heard from entrepeneurs and people i admire, it correlates with my personal experiences, goals and so i'm believing them like a sheep...similar to some students believing everything they get teached in college ....and i'm aggreeing that this channel is excellent, especially rhonda patrick...i would have loved to have a discussion with her before i got brain damage
FoundMyFitness - Thank you! This is brilliant. I just read an article on sensorineural hearing loss and 5-MTHF in a Life Extension Magazine. But your discussion is more in-depth, hence allowing a much better understanding, not only of polymorphisms and 5, 10-methylenetetrahydrofolate plus supplementation of 5-MTHF, not only of how riboflavin (B2), pyridoxal-5'-phosphate (B6) and thiamine (e.g., benfotiamine) fit into the picture as co-enzymes, but of polymorphisms and everything else you discuss. Top post! !
Siarhiej Rutenka she is awesome and you might possibly enjoy Dr Jordan Peterson who is as lovely and informative but in the genre of psychology and philosophy. He Harvard and Toronto University professor.
@@standinginson1 laughed my ass off at your response.. JP doesn’t do research, he preys on young guys with emotive lifestyle waffle, pseudo psychology and politically conservative tripe from his perspective of an idealised 1950’s. He stopped studying around the time psychology became a real science discipline, and relies on Freudian and Jungian ideas that have no basis in reality. He’s a god of misogynistic incels, repellent to real science and genuine social scientists.
Thank you Rhonda. You really boosted my interest and knowledge in a healthy lifestyle. Because of all the genuine science you are backing up your arguments with. Unlike bro-science. You are what I was looking for since I was getting slightly irritated by my government (dutch) generic dietary advices. This is information I can share with my surroundings.
I absolutely love your heart and brain for performing your research for us in video after video. You're clear, concise, and sweet! Thank you so much - absolute gratitude!
Your podcast has been instrumental in understanding the health conditions I have and how everything is connected. I'm totally geeking out on your topics and feel like you're show is expanding my brain!!
You can opt out of most data retention. The data they could potentially sell to third parties is anonymized. I believe you can also opt out of all data retention by deleting your account after downloading the raw data to generate your report.
Considering for example that sometimes there are more than one SNP involved in an specific disease or one SNP is in metabolic pathways associated with more that one disease or physiological process (ie. injuries, sports performance) . It is very important to consider that there is not enough information yet to personalized nutrition based on genetics for every health, sickness, etc profile. But is totally true that genetic tests are helpful to improve nutrition and supplementation strategies.
I'm part of the 1.7% that is APOE 4/4. Good to hear that you are working on this as the information about diet seems mixed. On the flip side, I do have the best version of FOXO3
This video has been a goldmine to use as a reference for polymorphisms, thank you! Is there other resources that give insights into the comprehensive reports from foundmyfitness? TIA!
I’m glad I found your channel! Thank you Joe Rogan for having DR. Rhonda on your podcast! I know you have time constraints so your videos are not very long. Very informative. Having said this, sometimes my ADHD has problems following you due to the tempo you use. (Something I’ll just have to overcome hence my watching the videos you provide). Where can one purchase (or find) your published papers? Have you written a book on your nutritional studies? I like to learn all I can about the human body and what foods we should be consuming. Thanks for reading in advance.
i would love too see a discussion between you and dr michael greger about the nutrition topic and basically discuss if we need animal products or not, since you recommend stuff like eggs and fish in this video, btw is there a gene that makes ppl remember a lot of stuff? since i think you definitelly got it
I bet they’d find they have more in common than not. Many plant based doctors aren’t as extreme as they’re made out to be and they usually promote a whole food plant predominant diet but have commented a little bit of animal protein in small amounts is fine.
Hi Rhonda -- would love to see a video/many videos regarding nutrition and mental health (nutritions impact on depression/anxiety/etc). Your thoughts on serotonin production. Or an interview with someone specializing in this area.
Great stuff Rhonda! I have been listening to you for quite a while now. Is there a place you can get a list of the currently known genetic factors (polymorphism’s, etc..) that you would take into account when personalizing a nutrition and fitness plan? Any good books that consolidates this information? Thanks!
Thanks for this informative video. Thanks to watching this, I sent my raw data to a practitioner at elevated health solutions online who interprets this stuff. I'll be getting a report about my polymorphisms to tell me which nutrients I need, what supplements, what foods and things to avoid or increase. This can all be so confusing. Your video definitely helped me understand. Can't wait for my report too!
THANK YOU Dr. Patrick! I've been geeking your videos for a week, and I've learned a lot. LOVE your approach. So all the SNPs you talked about in this video are in the 23andme? How accurate and actionable is the data? The disease predictions are just correlations right? The SNP seems to be more actionable, as in take these supplements, eat this way ect..I'm I correct? Just having the gene doesn't mean its on though so I'm questioning the usefulness, what I'm missing? I've been researching about the MTHFR and it seems like the pathways would be more usefull as it tells you whats actually going on in your body instead of just your genotype. Am I wrong? So is it in fact possible to over methylate? Thank you for all your work. I just subscribed.
I found you when you were on the Joe Rogan channel, at that time i was fasting wrong. I started the time restricted eating method and lost more than 20 pounds of solid fat while also gaining lean muscle mass. Thank you for exposing the knowledge on how to really build muscle without any drugs like steroids.
"Gibbs, where's my Caf-Pow?!!" Seriously, thanks Rhonda. I especially appreciate your "Rebuttal to Anti-Vitamin Editorial: Enough is Enough." Interestingly, the methyl folate supplement, methyl in my B12, other specifically-tailored supplementation, and a WFPB diet are why I haven't had another heart attack in 12 years. Keep up the good work!
Dr. Rhonda Patrick, thanks for the awesome videos. I was wondering if you could do a video on what foods you eat and avoid. For us non science people, it's really difficult to figure out what not to eat (other than the conventional processed foods). I have been doing a combo of the ketogenic and paleo diet. What foods do you avoid?
Reasonably customizing one's diet according to the knowledge we can obtain from cheap and easily availible tests seems to me the future of medical care. It sure beats the generic, one-size-fits-all recommendations so often churned out by the current medical industry. Rhonda Patrick consistently puts out useful information that I've never seen anywhere else. It sure can get complicated at times though!!
I had the gene testing by Oxford Recovery in Brighton Mi. That information was vital to make the changes in my diet to become healthy. I have reduced inflammation and my blood work came back normal
BEST BEST BEST - have been trying to decide about taking the 23andme - I only want to know things I can do something about - so your information is invaluable - Have searched all over the internet and this by far is the clearest explanation.
This info converges well with what I've already learned and adds some important insights. For me, it's been about sensitivity to methyl donors and PEMT mutation.
You mentioned that you will cover Apoe4 in a future video. Does tht video exist? I am apoe3/4 with a history of TBI and I am looking for information on how to manage my risk Thanks!
@@askingyou4life There's APOE2, APOE3 and APOE4 markers in your genes that reflect your chance of getting dementia, APOE2 being the best, APOE4 you'd have the greater chance of getting Alzheimer's. The 3/4 means that theAPO3 comes from one of your parents; the APOE4 from your other pareent. There's genetics and epigenitics where we can change much of our genetic signaling systems, at least 90%.
Yes, as another 3/4 I'm disappointed she didn't get around to this. However, Rhonda did write a 2018 paper = found at www.fasebj.org/doi/10.1096/fj.201801412R - which seems to suggest that DHA supplements don't work so well for APOE4's. We have to get our DHA from fish directly. Do you think I'm reading that correctly?
I loved this video, and love your channel! You talk a lot about preventing aging and disease... have you ever looked into management of autoimmune disease? I would LOVE to hear what is your take on it...
Thank you dr. Rhonda Patrick here is my story my son told me about you and your green smoothie I was border line to be diabetic I started to make the smoothie and drink it every day 3 months later I did blood work and visited my dr. And I ask how is my sugar level and his answer was perfect thank to you dr. Rhonda Patrick I’m not diabetic I won’t stop drinking this wonderful green drink
Hi Rhonda, Amazing videos, thanks. Any chance of that in depth video in Apoe4? I did listen to the end of that Rogan podcast which was good, but it'd be great to get a nutritional run-down specifically for Apoe4s. I think I have enough info from your smoothies to get going anyway. Thanks
Dr. Patrick is filling a vast void between known genetic science and the general public's awareness of this crucial information. Saying "thank you" seems criminally inadequate.... but thank you!
This video is exactly what I've been looking for. It is very helpful and needs to be shared with everyone. Thank you Dr Rhonda Patrik you've literally changed my life...for the better 😃👍
I have a question: I've been wanting to get my 23andme done ever since you suggested it on JRE. It's sort of expensive though. If my identical twin brother and I split the cost and sent out one sample, would we have a pretty good idea that the results applied to both of us? I know this is kinda goofy, just wondering if we can save some money. Love all of your videos and your podcast!
Hello and thank you! I had my tests done and had a nutritionist explain but am still feeling a lot of confusion as one gene mutation can ask for what another says to not do or eat. Are you available are for phone consultations? Or do you take new patients?
I just wanted to say that I only recently heard of you when I listened to a podcast you did with Joe Rogan. I am just an average 45 year old guy that's at a point where I want to do something good for my health now and into the future after spending my youth pretty much abusing my body.Your podcast with Joe really brought home to me just how poorly educated I am and I dare say many others are about how to fuel and treat our bodies in order to have the best possible life both physically and mentally. I don't mind admitting that I find the prospect of educating myself about the different facets of health to be more than just a little intimidating, particularly when I have now become aware of just how little I know. Hell I've now realized just how little I know about myself as an individual and where my needs may differ greatly from others.Wading through this information is going to be something of a task for me but I am so very appreciative of the fact that you put it out there for us. Thank you
Dr Patrick I feel compelled to share with whomever may care my own personal diet I did to lose weight. I make one roll of Hickory Farm sausage last three days along with one box of crackers of your personal choice, I eat Nabisco. Add two packs of ramen noodles a day with that portion of sausage and crackers and live some in that and walk at least a mile a day. It really worked for me but I’m pretty sure Dr Patrick here would not recommend it but it got the job for for me. It economical too obviously. One person out there has to benefit from this.
Thank you for the video! You say (effectively) that homocysteine levels correlate with vascular diseases. Forgive my ignorance, but how sure are we that high homocysteine levels are causative (or play a role in causation), vs. being a side-effect of vascular disease, or even an effort by the body to mitigate existing vascular disease? Thanks!
I have been diagnosed with a blinding disease, retinitis pigmentosa. Is it possible for you to make a video on how we in general can improve or protect our eyesight? plz..
Are the initiatory tests available or accessible to patients outside the US through the use or downloading of apps or other means as specified or recommended by your website?
I recently ran the comprehensive report on the Found My Fitness website based on my 23 and me data, and found the results quite fascinating. I am wondering if the Promethease report is more or less the same thing, or would it show more or different information?
Did twenty three and me pay you to say this? Do they sponsor you now or have they sponsored you in the past? Do you have any financial interest in the company?
I sucked a sciences. But, I'm wondering what raw data is provided? Is it very specific to these biomarkers or can we get the data processed for these biomarkers and also for other things like metabolism, etc?
Dr. Rhonda, would you please share your opinion on magnesium stearate, the flow agent manufacturers use for the making of supplements . One study shows there is nothing to worry about the next study shows there is great concern. When trying to balance my nutrients and diet I find this confusing when shopping for supplements.
Fro MTHFR if my ...1133 is good (CC) and only my ...1131 is bad (AC) am I still in the second category of 70% decrease? Same with APOE4 if my ...358 is good (TT) and only my ...7412 is bad (CC) must both be bad for it to be bad? Also I'd love for you to cover mold sensitivities and do 23andme show data on biotoxins, etc? Love your podcast!
Brilliant video and thank you so much for listing the rsid numbers! This is really fascinating to learn about highly useful! I noticed that on the MTHFR gene, for rs1801133 my raw data is showing AA (in the video, it's either T or C) and for rs1801131 it's showing up as TT (in the video it's either A or C). Did these numbers become switched around somehow?
lucabrazi36 Luca, I used 23andMe for my data and ran it through Promethease. You can, however, use other testing companies and still use the Promethease interface (though, they may not test for the exact same SNPs).. 23andMe is just one option that does give you access to download your raw data.
Go to www.23andme.com and pay $99 for your saliva kit. Send the kit off and wait 4 - 6 weeks for the raw data to be available, then go to www.promethease.com/ondemandagreed and pay $5. Results are displayed almost immediately.
Still discovering this in 2021. I'm so grateful for JRE introducing Dr. Rhonda Patrick into my life back in the day. Without her infinitude of knowledge my health would not have been what it is today.
I wish to take advantage of 23 and me testing to determine a personalized nutrition plan. I looked the 23 and me website and saw that they have 2 levels of testing, Ancestry Service and Health and Ancestry. I wonder if the basic Ancestry testing have the raw data to use either Promethease or Found my Fitness? Since this video was released in 2015 I don't know if things have changed.
I just checked the FAQ’s on their website. You only need to do the Ancestry. My son just sent me the link. I did not test for health, I did ancestry only.
Just learned my homozygous c677t mutation. Taking methylated vitamins. Now...how can I get better mag absorption? I am sprouting broccoli seeds and adding inulin. What type of mag supplement absorbs best?? Thank you!
Regarding MTHFR: Supplementation with 480mcg of L-methyltetrahydrofolate? Do you mean 4800mcg? 480mcg is only .48mg (less than half a milligram). That is nowhere near enough to make any noticeable difference. I think you're confusing the 480mcg daily intake for folic acid
Starting in 2011, I had severe spells of nausea, vomiting, and passing out that would come on suddenly and randomly after eating. It started with once a month in my 30s then after a few years these episodes could be 1-3 times a week and basically shut me down for 1-2 days. Id wake up with full body tingling like I was being hit with a cattle prod. After finding out that I have the MTHFR TT and MTRR AA (ironically from Rhonda's genetic services), I started taking a methylated B-complex, methylfolate, and alot of methyl b12. Results after just a few days -- 100% my symptoms were gone and that was over a year ago with no relapse. This information and vitamin therapy literally saved my life as I was becoming terrified to eat yet my doctors couldn't find anything. Cant stress enough how debilitating these episodes were and how radically different my life is once I gave my body what it needed to survive.
Dr Rhonda Patrick is just bad-ass. Seriously her energy and research is so awesome.
Thanks universe for making Rhonda Patrick possible.
and no thanks universe for creating such a flawed organism as the human evidenced by needing Rhonda Patrick
You guys should just thank God.
no. we only have ourselves.
MrHo16 The God who created the universe. There is only one entity able to do so.
@@LeonardoUA-cam8
doesnt exist
Your information is changing my life. I am so motivated to eat healthier and watch my micronutrients. I first heard you on The Joe Rogan Experience and I'm so glad you have your own channel! Thank you for providing us with all this information, you're definitely making an impact!
+Ana Veloso Me too, obsessed with these podcasts!
Same!
Ana Veloso Me too. I came across Dr Patrick by chance. She is now my favorite health communicator.. Her detail is incredible...
Nick H then listen to Dr. Darren Schmidt
# metoo
This channel is like a trip back to college. I learn an incredible amount with every video. Love it!
if you learn alot from this channel .... why you comparing it to college?
@@snubdawg1386 Maybe it was a good College?!?
@@snubdawg1386 your response speaks of *YOUR* experiences with college, not Jovanka’s, and you will already know there’s a tremendous variation in quality of education. I’m fully agreeing with @Jovanka Ciares, this channel is excellent.
@@PhilWhelanNow i have no experience with college ....after i learned how to write, read and do basic math i was done with the school system.... i'm only repeating what i heard from entrepeneurs and people i admire, it correlates with my personal experiences, goals and so i'm believing them like a sheep...similar to some students believing everything they get teached in college ....and i'm aggreeing that this channel is excellent, especially rhonda patrick...i would have loved to have a discussion with her before i got brain damage
FoundMyFitness - Thank you! This is brilliant. I just read an article on sensorineural hearing loss and 5-MTHF in a Life Extension Magazine. But your discussion is more in-depth, hence allowing a much better understanding, not only of polymorphisms and 5, 10-methylenetetrahydrofolate plus supplementation of 5-MTHF, not only of how riboflavin (B2), pyridoxal-5'-phosphate (B6) and thiamine (e.g., benfotiamine) fit into the picture as co-enzymes, but of polymorphisms and everything else you discuss. Top post! !
Probably the coolest doctor on UA-cam :D. Very informative and well made videos!
Siarhiej Rutenka she is awesome and you might possibly enjoy Dr Jordan Peterson who is as lovely and informative but in the genre of psychology and philosophy. He Harvard and Toronto University professor.
@@standinginson1 laughed my ass off at your response.. JP doesn’t do research, he preys on young guys with emotive lifestyle waffle, pseudo psychology and politically conservative tripe from his perspective of an idealised 1950’s. He stopped studying around the time psychology became a real science discipline, and relies on Freudian and Jungian ideas that have no basis in reality. He’s a god of misogynistic incels, repellent to real science and genuine social scientists.
I love it when youtube videos talk to me like an adult
Right!
Jack Thompson I find her hard to follow due to fearful rapid pressure of speech.
@@charlesjacques750 lol right? It’s like robotic and so pressured.. (no offense Rhonda if you read this.. lol)
@@charlesjacques750 ... slow down the volume. She just wants to avoid long, drawn-out videos.
Would love a new version of this! (Annual video would be pretty awesome)
Thank you Rhonda. You really boosted my interest and knowledge in a healthy lifestyle. Because of all the genuine science you are backing up your arguments with. Unlike bro-science.
You are what I was looking for since I was getting slightly irritated by my government (dutch) generic dietary advices. This is information I can share with my surroundings.
I absolutely love your heart and brain for performing your research for us in video after video. You're clear, concise, and sweet! Thank you so much - absolute gratitude!
This would be a nice subject to discuss if you plan on going on Joe Rogan's podcast again.
MikeRoePhonicsMusic Yup. I hope she'll soon be on the podcast again. I really enjoyed the previous episode.
Your podcast has been instrumental in understanding the health conditions I have and how everything is connected.
I'm totally geeking out on your topics and feel like you're show is expanding my brain!!
VERY nice overview of the genomics.
William Domb, DMD
This is exciting news. But aren't there privacy concerns?
You can opt out of most data retention. The data they could potentially sell to third parties is anonymized. I believe you can also opt out of all data retention by deleting your account after downloading the raw data to generate your report.
Considering for example that sometimes there are more than one SNP involved in an specific disease or one SNP is in metabolic pathways associated with more that one disease or physiological process (ie. injuries, sports performance) . It is very important to consider that there is not enough information yet to personalized nutrition based on genetics for every health, sickness, etc profile. But is totally true that genetic tests are helpful to improve nutrition and supplementation strategies.
Can you do a video on the methylation cycle and how all the genes within that cycle interact?
Thanks Rhonda ... your my GURU ...70 Going On 100
One of the only UA-cam channels you can actually rely on
I'm part of the 1.7% that is APOE 4/4. Good to hear that you are working on this as the information about diet seems mixed. On the flip side, I do have the best version of FOXO3
This video has been a goldmine to use as a reference for polymorphisms, thank you! Is there other resources that give insights into the comprehensive reports from foundmyfitness? TIA!
I’m glad I found your channel! Thank you Joe Rogan for having DR. Rhonda on your podcast!
I know you have time constraints so your videos are not very long. Very informative. Having said this, sometimes my ADHD has problems following you due to the tempo you use. (Something I’ll just have to overcome hence my watching the videos you provide).
Where can one purchase (or find) your published papers?
Have you written a book on your nutritional studies? I like to learn all I can about the human body and what foods we should be consuming.
Thanks for reading in advance.
love it. would love to see a video on FODMAPs and IBS.
"Now that we have all of the basics out the way"
😥
🤯
You're awesome. Clear, concise, and concerned for humanity. Thank you.
i would love too see a discussion between you and dr michael greger about the nutrition topic and basically discuss if we need animal products or not, since you recommend stuff like eggs and fish in this video, btw is there a gene that makes ppl remember a lot of stuff? since i think you definitelly got it
vegan freaks are out to get us.
its about scientific discussion not about emotions
I was just thinking the same thing. Call it: Battle of the Brains.
I bet they’d find they have more in common than not. Many plant based doctors aren’t as extreme as they’re made out to be and they usually promote a whole food plant predominant diet but have commented a little bit of animal protein in small amounts is fine.
Hi Rhonda -- would love to see a video/many videos regarding nutrition and mental health (nutritions impact on depression/anxiety/etc). Your thoughts on serotonin production. Or an interview with someone specializing in this area.
Great stuff Rhonda! I have been listening to you for quite a while now. Is there a place you can get a list of the currently known genetic factors (polymorphism’s, etc..) that you would take into account when personalizing a nutrition and fitness plan? Any good books that consolidates this information? Thanks!
Thanks for this informative video. Thanks to watching this, I sent my raw data to a practitioner at elevated health solutions online who interprets this stuff. I'll be getting a report about my polymorphisms to tell me which nutrients I need, what supplements, what foods and things to avoid or increase. This can all be so confusing. Your video definitely helped me understand. Can't wait for my report too!
Thanks Dr. Patrick for this awesome report. Made it super easy for me to wade through. Going to make some tweaks based off the data immediately!
THANK YOU Dr. Patrick! I've been geeking your videos for a week, and I've learned a lot. LOVE your approach.
So all the SNPs you talked about in this video are in the 23andme?
How accurate and actionable is the data? The disease predictions are just correlations right? The SNP seems to be more actionable, as in take these supplements, eat this way ect..I'm I correct? Just having the gene doesn't mean its on though so I'm questioning the usefulness, what I'm missing?
I've been researching about the MTHFR and it seems like the pathways would be more usefull as it tells you whats actually going on in your body instead of just your genotype. Am I wrong?
So is it in fact possible to over methylate?
Thank you for all your work. I just subscribed.
I found you when you were on the Joe Rogan channel, at that time i was fasting wrong. I started the time restricted eating method and lost more than 20 pounds of solid fat while also gaining lean muscle mass. Thank you for exposing the knowledge on how to really build muscle without any drugs like steroids.
Do you know whether they still provide raw data now that it's FDA approved and the reports are different?
"Gibbs, where's my Caf-Pow?!!" Seriously, thanks Rhonda. I especially appreciate your "Rebuttal to Anti-Vitamin Editorial: Enough is Enough." Interestingly, the methyl folate supplement, methyl in my B12, other specifically-tailored supplementation, and a WFPB diet are why I haven't had another heart attack in 12 years. Keep up the good work!
Dr. Rhonda Patrick, thanks for the awesome videos. I was wondering if you could do a video on what foods you eat and avoid. For us non science people, it's really difficult to figure out what not to eat (other than the conventional processed foods). I have been doing a combo of the ketogenic and paleo diet. What foods do you avoid?
Reasonably customizing one's diet according to the knowledge we can obtain from cheap and easily availible tests seems to me the future of medical care. It sure beats the generic, one-size-fits-all recommendations so often churned out by the current medical industry. Rhonda Patrick consistently puts out useful information that I've never seen anywhere else. It sure can get complicated at times though!!
I had the gene testing by Oxford Recovery in Brighton Mi. That information was vital to make the changes in my diet to become healthy. I have reduced inflammation and my blood work came back normal
Tim Kipp that’s great! I’m local to them; why did you do their testing rather than use 23 and me?
Baribrooks I did both.
BEST BEST BEST - have been trying to decide about taking the 23andme - I only want to know things I can do something about - so your information is invaluable - Have searched all over the internet and this by far is the clearest explanation.
This info converges well with what I've already learned and adds some important insights.
For me, it's been about sensitivity to methyl donors and PEMT mutation.
what is that Donovan? Pemt
You mentioned that you will cover Apoe4 in a future video. Does tht video exist? I am apoe3/4 with a history of TBI and I am looking for information on how to manage my risk
Thanks!
Whats Apoe4 and apoe 3/4 ?
blabli are you fucking serious? 😂
@@askingyou4life There's APOE2, APOE3 and APOE4 markers in your genes that reflect your chance of getting dementia, APOE2 being the best, APOE4 you'd have the greater chance of getting Alzheimer's. The 3/4 means that theAPO3 comes from one of your parents; the APOE4 from your other pareent. There's genetics and epigenitics where we can change much of our genetic signaling systems, at least 90%.
@@cathrynp3491 Thank you
Yes, as another 3/4 I'm disappointed she didn't get around to this. However, Rhonda did write a 2018 paper = found at www.fasebj.org/doi/10.1096/fj.201801412R - which seems to suggest that DHA supplements don't work so well for APOE4's. We have to get our DHA from fish directly. Do you think I'm reading that correctly?
I loved this video, and love your channel! You talk a lot about preventing aging and disease... have you ever looked into management of autoimmune disease? I would LOVE to hear what is your take on it...
Look up a book called, (The Lost Book Of Herbal Remedies) i believe this will help you.
Such amazing information as always, thank you Dr. Patrick!
Thank you dr. Rhonda Patrick here is my story my son told me about you and your green smoothie I was border line to be diabetic I started to make the smoothie and drink it every day 3 months later I did blood work and visited my dr. And I ask how is my sugar level and his answer was perfect thank to you dr. Rhonda Patrick I’m not diabetic I won’t stop drinking this wonderful green drink
Hi Rhonda, Amazing videos, thanks. Any chance of that in depth video in Apoe4? I did listen to the end of that Rogan podcast which was good, but it'd be great to get a nutritional run-down specifically for Apoe4s. I think I have enough info from your smoothies to get going anyway. Thanks
Dr. Patrick is filling a vast void between known genetic science and the general public's awareness of this crucial information. Saying "thank you" seems criminally inadequate.... but thank you!
How do they provide you with raw data? Is it a file we just upload to your site?
This video is exactly what I've been looking for. It is very helpful and needs to be shared with everyone. Thank you Dr Rhonda Patrik you've literally changed my life...for the better 😃👍
You have MAD SPEAKING SKILLS! I am in awe.
Expecting to see,results of YOUR
Work on APO4E.
THANKS FOR THIS GREAT INFO ON
MANY SUBJECTS
I'd love to hear your thought's on Weston A price and Sally Fallon especially about the synergy between Fats vitamin A, D and k.
MTHFR explained with brevity and clarity. What a great video.
wow, thank you, Rhonda! many blessings on your way -enjoy!
I have a question: I've been wanting to get my 23andme done ever since you suggested it on JRE. It's sort of expensive though. If my identical twin brother and I split the cost and sent out one sample, would we have a pretty good idea that the results applied to both of us?
I know this is kinda goofy, just wondering if we can save some money.
Love all of your videos and your podcast!
Identical twin ?
Thanks for your gene tool that uses 23&me data. I've used it to get some good insight.
Hello and thank you! I had my tests done and had a nutritionist explain but am still feeling a lot of confusion as one gene mutation can ask for what another says to not do or eat.
Are you available are for phone consultations? Or do you take new patients?
This video is ahead of its time
I just wanted to say that I only recently heard of you when I listened to a podcast you did with Joe Rogan. I am just an average 45 year old guy that's at a point where I want to do something good for my health now and into the future after spending my youth pretty much abusing my body.Your podcast with Joe really brought home to me just how poorly educated I am and I dare say many others are about how to fuel and treat our bodies in order to have the best possible life both physically and mentally. I don't mind admitting that I find the prospect of educating myself about the different facets of health to be more than just a little intimidating, particularly when I have now become aware of just how little I know. Hell I've now realized just how little I know about myself as an individual and where my needs may differ greatly from others.Wading through this information is going to be something of a task for me but I am so very appreciative of the fact that you put it out there for us. Thank you
This is absoluetely amazing, incredible times we live in
thank you for actively sharing this stuff. free the information
Thanks Rhonda, love your work :-)
Dr Patrick I feel compelled to share with whomever may care my own personal diet I did to lose weight. I make one roll of Hickory Farm sausage last three days along with one box of crackers of your personal choice, I eat Nabisco. Add two packs of ramen noodles a day with that portion of sausage and crackers and live some in that and walk at least a mile a day. It really worked for me but I’m pretty sure Dr Patrick here would not recommend it but it got the job for for me. It economical too obviously. One person out there has to benefit from this.
I forgot to add that you can eat as many apples 🍎 and banana’s too on my diet.
Thank you for the video! You say (effectively) that homocysteine levels correlate with vascular diseases. Forgive my ignorance, but how sure are we that high homocysteine levels are causative (or play a role in causation), vs. being a side-effect of vascular disease, or even an effort by the body to mitigate existing vascular disease? Thanks!
Hi Rhonda! Can you please do an update on nutrition and genetics, especially based on 23 and me data? Thank you!
I have been diagnosed with a blinding disease, retinitis pigmentosa. Is it possible for you to make a video on how we in general can improve or protect our eyesight? plz..
Are the initiatory tests available or accessible to patients outside the US through the use or downloading of apps or other means as specified or recommended by your website?
Does the Found My Fitness genetic tool identify MTHFR C677T? (I believe that it might not, and that surprised me.)
I recently ran the comprehensive report on the Found My Fitness website based on my 23 and me data, and found the results quite fascinating. I am wondering if the Promethease report is more or less the same thing, or would it show more or different information?
Excellent presentation. Is their a place I can get this checked?
Thank you, Dr Rhonda ! Very useful information!
Could you explain the metabolic pathway of COMT polymorphism?
I donated and used the foundmyfitness genetic tool, is this the same report as the promethease report that you mentioned in the video?
Nope, the genetic part of the website was added after this video. You can find promethease at promethease.com.
Did twenty three and me pay you to say this? Do they sponsor you now or have they sponsored you in the past? Do you have any financial interest in the company?
I sucked a sciences. But, I'm wondering what raw data is provided? Is it very specific to these biomarkers or can we get the data processed for these biomarkers and also for other things like metabolism, etc?
Hi Rhonda! Do you know if 23andme still tests for the apoe gene? the list on their website doesn't include it/
Hi may I ask how many polymorphism s are there csn you test for each of them?? Would you be so kind to let us know them and what you can be tested for
You are amazing! This information has been life changing for me and my partner! Thank you!!
But does it really make a noticeable difference when you remove certain foods/nutrients from your diet?
Willing to bet it makes fuck all difference.
I have every polymorphism you mentioned, except the choline one. Is there a multi vitamin you can recommend?
Dr. Rhonda, would you please share your opinion on magnesium stearate, the flow agent manufacturers use for the making of supplements . One study shows there is nothing to worry about the next study shows there is great concern. When trying to balance my nutrients and diet I find this confusing when shopping for supplements.
Your research does something good to my brain!
Fro MTHFR if my ...1133 is good (CC) and only my ...1131 is bad (AC) am I still in the second category of 70% decrease?
Same with APOE4 if my ...358 is good (TT) and only my ...7412 is bad (CC) must both be bad for it to be bad?
Also I'd love for you to cover mold sensitivities and do 23andme show data on biotoxins, etc? Love your podcast!
Brilliant video and thank you so much for listing the rsid numbers! This is really fascinating to learn about highly useful!
I noticed that on the MTHFR gene, for rs1801133 my raw data is showing AA (in the video, it's either T or C) and for rs1801131 it's showing up as TT (in the video it's either A or C).
Did these numbers become switched around somehow?
***** Hi, Kannon! Thanks! This page explains what's going on there... www.snpedia.com/index.php/Orientation
@@FoundMyFitness This was confusing for me as well. Thanks for the snpedia link!
Priceless, as per typical for the good doctor!!!!
Hello Dr. Where can I get these tests done to see what polymorphisms are in my genes? I live in the bay area in northern CA
lucabrazi36 Luca, I used 23andMe for my data and ran it through Promethease. You can, however, use other testing companies and still use the Promethease interface (though, they may not test for the exact same SNPs).. 23andMe is just one option that does give you access to download your raw data.
Go to www.23andme.com and pay $99 for your saliva kit. Send the kit off and wait 4 - 6 weeks for the raw data to be available, then go to www.promethease.com/ondemandagreed and pay $5. Results are displayed almost immediately.
Julia Patrick damn it! its half the price of Canadians :(
map my genes is also really interesting but super expansive!
Hi Dr. Patrick, could you please recommend a diet that targets the genes in balding men to help restore hair? thank you , very fond of your work!
She knows this stuff by heart. Notice that her eyes don't move left and right. She just stares forward. Not reading anything. She's good!
After positive lifestyle changes can you be retested to denote that proclivities to illness have been reduced or eliminated?
I mean does that company also provide the raw data? Cuz I took an ancestryDNA brand one
Still discovering this in 2021. I'm so grateful for JRE introducing Dr. Rhonda Patrick into my life back in the day. Without her infinitude of knowledge my health would not have been what it is today.
Looking forward to the apoe research.
Maybe do LP(a) video please. Mine is 495, it's scaring the hell out of me
Should i get 'ancestry service' or 'health + ancestry service', if i get the first one can i still use that tool you were talking about? tankyouu
Best diet info on the tube
THANKYOU FOR ALL OF THIS INFORMATION
I have one copy of the MTHFR gene. Does this mean that I should be taking a B12 vitamin/folic acid?
Thank you Dr. Rhonda....!
Love You !
I wish to take advantage of 23 and me testing to determine a personalized nutrition plan. I looked the 23 and me website and saw that they have 2 levels of testing, Ancestry Service and Health and Ancestry. I wonder if the basic Ancestry testing have the raw data to use either Promethease or Found my Fitness? Since this video was released in 2015 I don't know if things have changed.
Samuel Pierson no you have to pay for the health not just the ancestry
I just checked the FAQ’s on their website. You only need to do the Ancestry. My son just sent me the link. I did not test for health, I did ancestry only.
Dave that's false I paid only for ancestry but still have the necessary raw data for stuff like this.
How about a video on how to deal with hyperlipidimea and triglicerides that are high due to a genetically caused liver condition.
Just learned my homozygous c677t mutation. Taking methylated vitamins. Now...how can I get better mag absorption? I am sprouting broccoli seeds and adding inulin. What type of mag supplement absorbs best?? Thank you!
Regarding MTHFR: Supplementation with 480mcg of L-methyltetrahydrofolate? Do you mean 4800mcg? 480mcg is only .48mg (less than half a milligram). That is nowhere near enough to make any noticeable difference. I think you're confusing the 480mcg daily intake for folic acid
such an amazing resource, thanks so much rhonda