CRISPR-Cas9 gene editing and how it works - with Jennifer Doudna
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- Опубліковано 9 лис 2015
- What is CRISPR-Cas9 and how does it work? How do we edit genes? Jennifer Doudna, biochemist at UC Berkeley, explains.
The gene editing technique, created by UC Berkeley biochemist Jennifer Doudna and her colleague, Emmanuelle Charpentier, director of the Max Planck Institute of Infection Biology in Berlin, has taken the research and clinical communities by storm as an easy and cheap way to make precise changes in DNA in order to disable genes, correct genetic disorders or insert mutated genes into animals to create models of human disease.
CRISPR-Cas9 is a hybrid of protein and RNA - the cousin to DNA - that functions as an efficient search-and-snip system in bacteria. It arose as a way to recognize and kill viruses, but Doudna and Charpentier realized that it could also work well in other cells, including humans, to facilitate genome editing. The Cas9 protein, obtained from the bacteria Streptococcus pyogenes, functions together with a “guide” RNA that targets a complementary 20-nucleotide stretch of DNA. Once the RNA identifies a sequence matching these nucleotides, Cas9 cuts the double-stranded DNA helix.
Read more about CRISPR: news.berkeley.edu/2015/11/12/c...
Video by Roxanne Makasdjian and Stephen McNally
Cas9 Apo Structure image by Ben.lafrance CC BY-SA 4.0
commons.wikimedia.org/wiki/Fi...
CRISPR animation provided by the Innovative Genomics Initiative
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A 20 y/old over here, studying biotech, excited to serve humanity with this technology!!
I'm also a 20 year old studying biotech!! It's mega hard sometimes but the fascination is real. I wish you luck on your professional journey!
Nobel prize no doubt.
Bro. What a predict.
Thankyou Dr. Jennifer for thinking about the world
Congrats Dr Doudna on your Nobel prize and Go Bears!
Well done, Jennifer.
Dr. Jennifer Thank you. Spread the Love❤️ Faith in God. You bring light into the world in science ways. Thank you Jennifer Doudna and thank you UC Berkeley
Marvellous invention. Congratulations.
Berkeley :3
I got psoriasis. So this stuff is of great interest to me. Also it's very, very interesting stuff, anyway!
Does anybody know the song from this video?
Kudos!!!!🙏
Congrats👍👍
NOBEL PRIZE!
Jean Fernandez so this legend predicted it 4 years back
This aged well
Amazing
Omg called it
can it fix allergy?
Yes
Biopunk era is begin?
this is it folks...the end as we know it.
God help us...
In some kinda way we are gods now.
We are not God, this will be sold to us as the best thing since slice bread, ultimately it will and probably all is being used for evil, unless the days be shortened there would be no flesh saved, but those days will be shortened!
Yes, corrupting all things made Gods way upon the earth, humans, animals, plants, fish, taking that which is natural and making it unnatural, breaking Gods creation laws!
[generic ignorant religious comment]
Go Bears 🐻
Oh no.
We need a cure for HIV, there are almost 40 years of desert, people who got hurt looking for Love, people who struggle every day, don't restrict the cure, it's painful! we pay taxes we are professionals, parents children mothers grandparents, this is in the hands of science and government, science with genetic research, government accelerating authorization, and not favoring an industry that profits from suffering. YHWH Raphael aj help us. 2021. Shalom!
custom design humans...here we come :)
+Hyder Noori not to worry, leftist morons (ie mostly european idiots) will ban it, they already have banned many other types of gene therapies. Thank goodness china does not care about european idiots
Nikos V If there's one thing to thank the Chinese government for :)
And there you have it a Weapon of Mass Destruction for you sir... Much obliged!
or a cure to my chronic illness.
@@gurpchirp we have stem cell research that can do incredible good, try getting it if your not a millionaire tho. This won't be for us it will be for the rich.
Inspiring major greed.
Yo this shit is going to make zombies... 😲😲😲😲😲😲😲
GOD said, be still and know that I Am God, not be still and know that you are God or be still and play God. If you alter the temple of God, male or female, the holy spirit will not dwell in those temples, if the spirit of the living God does dwell in them, guess what spirit will? Use your imagination! The days of Noah are here!