Sickle Cell Trait
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- Опубліковано 30 січ 2018
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For the longest I’ve been trying to figure out why I experience pain in my joints, and various parts of my body from time to time. Then it clicked, I’m a confirmed sickle cell carrier.
This was a very bad misleading explanation of the trait. The term “trait” alone is misleading. Doctors USED to believe the things you are saying, but know better now. Those with the trait typically have lower extremity pain and swelling often, they also typically suffer from minor iron deficiency anemia. The “extreme conditions necessary to cause death do not in fact have to be that extreme. Physical exertion (exercise, high temperatures, elevation changes... you know the normal things children and adults should be doing) have been know to cause severe responses. Women are known to have serious complications after giving birth. I really dislike how the medical community does not take this condition serious. No, isn’t as bad as full blown sickle cell, but it is still bad and still has complications. Doctors try to make the sufferers feel crazy when reporting the complications. According to ST Jude’s, “People with sickle cell trait have red blood cells that have normal hemoglobin A, and abnormal hemoglobin. The abnormal hemoglobin is called hemoglobin S. People with sickle cell trait have slightly more hemoglobin A than hemoglobin S. They have enough hemoglobin A to help their red blood cells carry oxygen to the body.” In other words those with Sickle Cell “Trait” DO have abnormal hemoglobin at all times, but just have enough to function with unnoticeable complications.
👏🏾 that's right! It's so frustrating that I can't find any answers for my "trait". Doctors always make me question what I know I'm feeling. You're so right
I have the trait.... and agree with your comment. I am currently still having issues with my red blood cell and the baby is 4yrs old, all from loosing a lot of blood during C-section
PREACH
Thank you for this,when I was 14 I found out an i was severely sick an even lost alot of weight in a short amount of time,I still feel sick some times an write of as not being anything, I felt faint an sick today and it passed but it's back again tonight
Has anyone also ever felt paralyzed like they cant move when the pain hits an have to just lay there until it passes?
I disagree people with Sickle Cell Trait can & some do experience pain!
That’s true...But generally, it is commoner in sickle cell anemia...I am only talking about overall rules, and am so sorry if you or anybody close to you is going through this.
Yeah, I think too often doctors are so quick to dismiss the dangers and complications that come with the sickle cell trait. Heck the term “trait” alone is misleading. People in the military and athletes are known to die from complications.
I have Sickle cell trait (HBaS) and i do not surfer any form of pain, never have to be honest.
Yes i have sickle cell deizese but my mom say i have the trait and i do have it and experience pain A LOT NOT KIDDING it's hard for me 😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭
I am so sorry to hear that!
Please follow up with your doctor!
I wish you the best of luck!
Don’t give up!
Bro sounds depressed
😁😁
I have it but it not that bad
My parents today told me i had sickle cell trait passed down to my father. My little brother also has it i just wanted to know more about it thx.
Thank you so much! I had a question about this and you really cleared up my qualms
My 20 yr old son was diagnosed with sickle cell trait at birth. He is white and so is his father and I too. The doctor's asked me what color his father was.
I later found out my grand fathers family was from Portugal and his family are called Melungeons. Apparently sickle cell trait & animia are inherited.
I need to learn more of this. I think he got SCT from me. I would like to have genetic testing...maybe some day..
Tf is a melingeon?
AM.YELLOW you can take a blood test named Hemoglobin Electrophoresis to find out if you have the sickle cell trait or not.
Your primary care doctor can do it, if you have one
@@FKAwalkwithwadea group of people from Appalachia
I’m 40 and have the trait. I’ve been pretty damn healthy all my life. I eat junk food though in moderation. No pain just some serious exhaustion now. Almost like narcolepsy. Like when I lay down I’m out in less than 1 min flat and I have to take a power nap during the day. I can sleep 12 hours at night and still need a power nap. It freaking sucks. I’m trying to get a sleep study now but I def think it has something to do with the sickle cell trait.
Your white blood cell might be low and platelets too. It happens in your case.
I'm 53 with the trait. Never sickly either. Mom said I had asthma as a youngin, but grew out of it. Allergies to some things too, but all seem to have cleared up as I've aged.
I was kind of a sickly child. I had a weak stomach and suffered from nosebleeds whenever my body got overheated. Not sure if those symptoms are connected to SCT (or maybe it's just me, as an individual). I also once fainted on a hot day at the fair (as a child). Oh, and I became anemic very easily (compared to the rest of my family who were never anemic) if I didn't have a meat with every meal.
When I joined the workforce from my 20s onwards, I couldn't understand why I was so exhausted after work every day (office jobs), especially for a person in their 20s who should be energetic and in the prime of their life. But I started attending the gym and that helped somewhat (in terms of energy). I went from feeling exhausted every day after work - to only feeling exhausted by the end of the week, lol! I needed to take it easy on Saturdays and just have a lay in (or drift in and out of sleep for most of the day).
When I hit my 30s, I started experiencing some autoimmune issues. Now I'm in my 40s and experiencing what I suspect to be perimenopause symptoms. It's a never-ending story for me 😭
I am exactly the same
Sickle~y no pun intended…
We’re not taken seriously until it’s time to harvest our blood for sickle cell patients. More research into SCT would not divert attention from SCD but would benefit it. Not to mention reproductive education about being a carrier and not passing on SCD….
Fatigue is the worst symptom for me. Not only physical but psychological. It presents as ADHD. Whether or not it’s caused by SCT is definitely real and unpleasant. Blanket statements about it causing no symptoms is plain ridiculous at this point.
Wow thank you so much now I understand it better
Thank you!
I am female & have the sickle cell trait, & suffer sharp stabbing (needle like) pain in joints & the head, it worsens under stress. It is severe & crippling sometimes. I suffer other symptoms associated with HBSS, it puzzles me because i hear a lot, its supposed to be benign?!!!
Its the same painful symptoms for 2 of my adult sons who are also sickle cell trait.
I don't think its benign for everyone!
You’re correct.
It’s not benign for everyone.
@@MedicosisPerfectionalis then change the video
have sickle cell trait and have joint pain, bone pain, very bad muscles and joints cramps, migraines, a lot of allergies and nausea. I also am constantly anemic and underweighted. So people with the trait do experience symptoms. My doctor says the symptoms depends on the percentage of sickle cells you have. The more you have the worst it is.
@@MedicosisPerfectionalis If it's not benign for everyone then please stop regurgitating incorrect information. Doctors have chalked up my ER visits to everything BUT my SCT because they believe it's "benign." Once they even told me they thought I had Multiple sclerosis and had me see a neurologist instead of simply considering the fact I have SCT.
I personally also have iron deficiency anemia and I have loss of consciousness. With sickle cell trait.
I suffer from sickle cell trait and in times of stress urinte blood (I urinated blood for 6 months before and the doctors thought It was cancer, until I had the CT scans, blood tests etc that's when I found out I was sickle cell trait) and I also get bad pins and needles on my left leg.
Is it common for people with sickle cell trait to urinate blood? Or to have blood in their urine? My blood tests came positive to sickle cell trait. I had CT scans, now the doctor wants me to come in for a cystoscopy.
@@ndalakalonda no it's not common to urinte blood if you have sickle cell trait. According my urologist consultant and Google, 1 in 1000 people with sickle cell trait can experience abnormal blood clots in their urine.
When I first saw blood in my urine I visited my GP, he asked me all the relevent questions ( am I in pain, am I sure it's not my period etc) the answers was all no! He then straight up told me that he thinks I have cancer. He then made an emergency referral to the hospital to get an ultrasound, CT scan, allot of blood tests (that's when I found out that I have sickle cell trait) I then I had a ureteroscopy scan. They found some blood clots in the kidney. Thank God it was not cancer or anything serious.
The urologist consultant said it's to do with my sickle cell trait. Only a few people may experience abnormal bleeding from time to time. Within the past 7 years I've urinated blood 3 times. The longest 6months. From my own observation when I'm mentally and physically stressed that's when I urinate blood and your body will stop on its own time.
For the past week, I've now been getting leg cramps on my left leg. It causes difficult sleeping. The last time I had legs cramps (4 months ago) I started urinting blood again which lasted 3 weeks. I again need to get it checked out.
Good luck at your appointment. Wishing you all the best 🙌🏽
@@user-jv3cz6zx3q wow. Thank you so much for the information. I truly appreciate that. Wishing you the best 🙌
Can you do a video about nutrition? And how to ensure kidney health if you have sickle cell trait? I'm not finding videos anywhere, just that I should take an iron supplement but I would like to know why the trait makes us at risk for kidney issues and stroke and how to prevent it 💖
Where did you read that?
Yeah where did you read it fam
Too much clear.... tq 😇
My pleasure 😇
When under extreme conditions how long does it take for the sickle cell to turn normal when you have the trait?
Not that long bc i have it
My hemoglobin varient test report says that there is 30% Hemoglobin S present in my blood. What does it means?
This is not accurate. Sickle Cell Trait is not a completely benign condition, and it does require management.
Does a carrier have sickel cell or hemoglobin S in their blood?
Wonderful video, just like all of your others. However, please be aware it is not an ENTIRELY benign condition. Those with sickle cell trait should avoid ever getting very dehydrated or overheated, and also should avoid high elevation (e.g. mountain climbing) and high pressure (e.g. deep sea scuba diving) conditions. Under these conditions, red blood cells can sickle in those with sickle cell trait. It is believed that rarely, SCT can contribute to kidney damage or sudden death. This typically happens during extreme athletic training.
Dehydration is huge as is high elevation and extreme exercise. A friend of the family died suddenly, she was late 50s. The medical examiner told her mother it was the sickle cell trait. Her mom refuses to believe it to this day. I think Dehydration may have been a big factor, but that's just my opinion.
Thank you sooo much ♥️♥️
My pleasure 😇
Is getting severely dehydrated apart of certain symptoms?
^
Yes you have to stay hydrated
You that so good , I was very scared of sickle cell , but now I understand, thank you so very much ❤❤ ❤ ❤ ❤ 😊❤❤😘😘😘😘😘
Thank you so much!
Just found out I have sickle cell trait. I have been sick most of my life and doctors didn't know what it is. So I don't totally agree with this, even people with sickle cell trait suffer with pain and should have it managed....
Me and my brother have the trait from our Dad. Now I've passed it onto my young son. I did some exercise yesterday morning and ever since I have intense joint and muscular pain, today I can barely walk I'm in so much pain. I'm left wondering if this is related to the trait as this just doesn't feel right.
If you haven’t exercised in a long time it could be muscle soreness from your body not use to exercise.
Yeah the average person experiences many of these things as well. Some just can handle exercise better than others.
Being sickle cell trait personCan we minimise the count of hbs in our blood so that HBA will be more and it there will be no sign of sickle cell carrier in blood ?
Most people with trait experience no symptoms whatsoever. Some do. Not only can people who have the trait not contract malaria, they cannot commute it. Even if exposed to it.
Same seems to apply with covid 19.
See
Jere , so if you have the sickle cell trait, does it make you resistant to COVID-19...? I saw something similar to this online, but I was not sure if it was valid. Is that what you heard..?
Not true I ve had it and I have the trait
No, people with siclke cell trait disorder are turned away from doctors and made to feel as if it's all in their heads. It is literally ignored. By doctors.
I have sickle cell trait and have had malaria so many times. So I never get when people say that. Also am always anemic, I have also had a blood transfusion once when my hemoglobin was 7
I disagree with this! I have the trait and in high (hot) temperatures and exhausting situations ( such as high intensite exercising for example) I feel pain, problems breathing and some dizziness! There isn't a lot of money to be made in further research of the impact of having the trait and how it can influence other illnesses ( such diabetes, heart conditions, lungs and kidneys) and even the absorption of medications. It's only when black sports ppl die that we get a bit more pertinent information. Very sad💔
oh wow that explains a lot.. i thought i was allergic to the sun or something (joking but not really) like it would get really bad to where heat was unbearable and painful not just “miserable” like most people get
with sickle cell trait your blood cells can and will sickle in less than extreme conditions
I have a friend who has sickle cell trait and he spits a lot and produces a lot of mucus. Can anyone help me pin what may be going on with him. He said he started experiencing these symptoms in 2021, 2 years from today
Right I know I can get pain in extreme measures
I'm a little confused. How is sickle cell trait due to the codominance phenomenon and yet at the same time you say sickle cell disease is a recessive disorder
Codominance and incomplete dominance phenomenons occur in the heterozygous genotypes. In this case, sickle cell TRAIT is the heterozygous codominance phenomenon, and sickle cell DISEASE is the recessive disorder caused by the recessive HbSS genotype. To directly address your question, the HbA allele is still partially dominant over the HbS allele, hence why a heterozygous individual experiences much more of the benign features than the disease symptoms.
@@ma7119_ Great video thank you so much. So can you also produce a video on having Sickle Cell Trait and the combination of Thalassemia Trait? I have read that the combination is rare. There are a group of people who have it and are told that it means a full blown disease which is often overlooked because it is so rare. Many examples of people having the combined traits are the athletic and military persons who then have episodes under stress and collapse having gone into a anoxic episode.
in sickle cell trait , does each RBC has both types of hemoglobin HbA+HbS ??. or there are RBCS have HbA ONLY and other RBCs have HbS ONLY ??
Great 👍 question!
I think each RBC has only 1 type of Hgb.
But, why does it matter?
@@MedicosisPerfectionalis
but should the co-dominance phenomenon exists which means that one cell expresses both genotypes at the same time ??
according to your answer , some RBCs express only maternal copy and shut down the paternal copy , and other RBCs do the opposite ..
it matters because if there are RBCs carry only HbS and other carrying HbA , the sickling would be much more than if one RBCs carry both types ..right ??
But what matters is is the overall picture, not an individual RBCs. I might have a sickled RBC right now, but I am fine because most of my RBCs are normal.
The genotype in diagram for carrier should be AS. Am i right. PLease see at 2:59 min
yes it should
Why is Egypt highlighted on the map?
I am from Egypt 🤗
@@MedicosisPerfectionalis i thought you were indian!
@@MedicosisPerfectionalis
I'm egyptian too
i don't get it, how can there be codominance if it's an autosomal recessive disease?
One disease can have many possibilities for the pattern of inheritance. For instance, Alport syndrome could be inherited in an X-linked recessive, autosomal recessive, or autosomal dominant fashion (but not simultaneously of course).
I just found out my 3 week old has the trait but I’m feeling a bit overwhelmed about her future
It’s generally benign (favourable) .. I have it to . Asymptomatic. One I was dating I made sure to ask from the get go whether they had Sickle Cell Trait because two individuals whom partner up their offsprings have a 25% chance of having Sickle Anaemia which is a horrible disease.
He or she needs to make sure she doesn’t marry anyone with sickle cell trait . I just found out that I have the trait ( got from my mother as she is AS) and also found out my partner’s got the trait as well . It sucks
@@princessokwale2075 They can marry hun, just not wise to have a child due to an increase risk of getting sickle cell.
Could me have an a trait be the reason I’ve always had an iron deficiency?
I don’t know 🤷♂️
Has SCT or disease ever been linked to close relatedness in parents?
Yes, because it’s autosomal recessive.
Can Aa and Aa parent produce a sickle cell trait baby ?
No
Curious about the ones with trait there are in the comments The ages I'm 36 live with it whloe my life But weirdly neither one of my parents have it Can someone explain this and can People tell me their ages Post their ages with the trait please
I’m 17 with trait ,
I'm Brazilian and I'm 46 years old but Just found I have the "trait" at about 40 ...
@@marciarodrigues1895 thanks
@@nightstarking it’s commonly still genetic even if your parents don’t have it someone in there gene had it and it just happened to skip them and go to you.
I HAVE PAIN ALL OF THE TIME!
Thank you so much, i love how you explain everything thoroughly.
Thank you!
Sir my sickle cell is trait
What medicine should i use
Talk to your doctor.
No one can treat you online
Folic acid
But how
It is in ONE amino acid!!
Can someone with SS genotype come down with malaria
It’s unlikely.
I got the trait and I feel pain sometimes
I believe you...I have read in a recent textbook that some people with trait have symptoms.
@@MedicosisPerfectionalis could you please give us the name of this book?
Can i get married to sickle cell trait woman ? Is there wil be any complications in future?
If you have it too your kids may have sickle cell anemia
So that's the cause of my black outs. It can happen even if I laugh too hard.
You coment in sickal call trait 100 parsnt wrong trait gate more comlacation
What does “gate” and “comlacation” mean?
Medicosis Perfectionalis I believe they probably made a mistake, but their overall comment was “your comment about the sickle cell trait is 100% wrong. The trait comes with a lot more complications. While I don’t agree with the 100% part, their overall sentiment is correct. The trait actually doesn’t need that “extreme” of a condition to cause complications. Often those with the trait have iron deficiency anemia as well. We suffer swollen lose extremities and heart rate differences. Heat, athletic exercise and other normal activities cause complications that have traditionally been ignored by the medical community due to racial biases. Athletes and service members are known to die during training and events when not closely monitored. It is not as acute as full sickle cell anemia, but it should be monitored closely.
@@boparks3204but if u have sickle cell trait and have modeate pain would u need a doctor to get medicine?
I was here 😬
Where?
I have the trait I hate winter time
I am sorry 😐
I just found out at 60 years after having a Pulmanologist embolism and found out I have Sickle Trait. I have a stress full life and have suffered joint pain all my life
nice lecture
Thanks a million!
Thanku very much sir
You are always welcome!
Anyone get bad headaches??
Sickle cell trait is definitely not asymptotic
You’re correct!
Hbs is 36.3
HbA is 59.3
I have sickle cell trait or not
Totally disagree with your content
This is not benign
You’re correct. It’s just less severe than the sickle cell disease/anemia.