How do you specify a MAMS model in R with the lme4 library (or any alternative)? (dropping arms and taking into account the correction of type-I errors? How do you compensate the error type-I when different arms have different duration?
Great stuff! Question: why is adaptive design a new thing? Bayes Theorem was formulated in the 18th century. Why has the so-called traditional trial design not been adaptive all along?
How do you specify a MAMS model in R with the lme4 library (or any alternative)? (dropping arms and taking into account the correction of type-I errors?
How do you compensate the error type-I when different arms have different duration?
Do we need to use cross-validation in bayesian analysis to control overfitting?
Great stuff! Question: why is adaptive design a new thing? Bayes Theorem was formulated in the 18th century. Why has the so-called traditional trial design not been adaptive all along?
Because bayesian analysis for real life problems is computationally very expensive, and it has needed the development of MCMC methods.