Cancer Immunotherapy: 2022 Research and a Look Ahead with E. John Wherry, Ph.D.

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  • Опубліковано 18 січ 2022
  • Renowned cancer immunotherapy expert E. John Wherry, Ph.D., discusses new research and treatments in the year ahead. #Immunotherapy #CRIwebinar www.cancerresearch.org/webinars
    - Promising new treatment strategies in patient care including combination treatments
    - What biomarkers are and how they’re important to formulating a treatment plan
    - Latest advances in cellular immunotherapy for solid tumors
    E. John Wherry, Ph.D., is the director of the Institute for Immunology, the chair of the Department of Systems Pharmacology and Translational Therapeutics, and the Richard and Barbara Schiffrin President’s Distinguished Professor at the University of Pennsylvania Perelman School of Medicine. He is also an associate director of the Cancer Research Institute Scientific Advisory Council. A leader in understanding T cell biology in the context of chronic infection and cancer, Dr. Wherry has published more than 200 papers and his research has been cited nearly 50,000 times in peer-reviewed publications.
    Cancer Immunotherapy and You Webinars™ are produced by the Cancer Research Institute and hosted by CRI Assistant Director of Scientific Content Arthur N. Brodsky, Ph.D. The 2022 series is made possible with generous support from Bristol Myers Squibb and Lilly Oncology.
    Browse our Cancer Immunotherapy and You Webinars playlist on UA-cam or visit the Webinars page on our website to see other webinars in this series. www.cancerresearch.org/webinars
    Established in 1953, the Cancer Research Institute (CRI) is a 501(c)(3) nonprofit organization dedicated to harnessing our immune system’s power to control and potentially cure all cancers. Our mission: Save more lives by fueling the discovery and development of powerful immunotherapies for all types of cancer. To accomplish this, we rely on donor support and collaborative partnerships to fund and carry out the most innovative clinical and laboratory research around the world, support the next generation of the field’s leaders, and serve as the trusted source of information on immunotherapy for cancer patients and their caregivers. www.cancerresearch.org
    Cancer Research Institute is a registered 501(c)(3) nonprofit under EIN 13-1837442. Donations are tax-deductible to the fullest extent allowable under the law.

КОМЕНТАРІ • 60

  • @IVORY123100
    @IVORY123100 2 роки тому +60

    I have Stage 4 Melanoma . They expected me to be dead in 2020 . Brain tumors are gone and I am back working . Either I have experienced a Miracle or immunotherapy works .. Perhaps both .. .. Keep a happy heart

    • @ApeSlayer
      @ApeSlayer 2 роки тому +2

      Amazing. What treatments did you take?

    • @jamuna123able
      @jamuna123able 2 роки тому +1

      My hubby has vertebral cancer metastasis to lungs..Kindly guide me brother

    • @anacastro9382
      @anacastro9382 Рік тому

      Hola me puedes decir cual es la inmunoterapia que usastes tú muchas gracias!

    • @geramx0
      @geramx0 Рік тому +2

      @@anacastro9382 hola te pido de por favo agas una investigación sobre la cola de pavo Trametes Versicolor i empieces a consumirlo en capsulas o tes y si esta muy avanzada tu enfermetad tomate 6 pastillas si solo la quieres para estar bien de salud tomate 2 al fia tu y tu familia de ante mano espero que mejores tu y tu familia.

    • @geramx0
      @geramx0 Рік тому

      Hey you should do a research about Turkey Tail Trametes Versicolor and start taking it and in 6 months I would like to hear about you.

  • @styzoom
    @styzoom 2 роки тому +9

    My dad benefited from immunotherapy for his stage 4 lung cancer. He was diagnosed in 2017 and still alive in 2022. Since over a year he only has chemo therapy as a treatment as the scans didn't show any cancer anymore. Stopping with immune therapy was difficult but the immunotherapy was quite tough with the severe side effects he got from it. So far so good with a milder therapy, but all the years going to the hospital is taking its toll too. I hope he lives for many more years. Quitting is not an option (yet), the risk it will come back quickly is apparent. When it comes back there is probably no way of stopping it again.

  • @christiandevito417
    @christiandevito417 2 роки тому +15

    Wow.. what we eat, how we exercise, how we deal with stress, how we care for our microbiom all play a role in our wellness. Glad to hear science is catching up with common sense. Thank you so much for this interview. Have shared it all over already.

    • @christiandevito417
      @christiandevito417 2 роки тому +5

      I need to add that I have been on Pembrolizumab for over a year and a half for Stage 4 HNSCC and have been NED for 16 months. I also made major dietary, exercise, spiritil/ mental health changes and know this has had a huge difference in my journey to wellness.

    • @em34ev3r
      @em34ev3r 2 роки тому

      @@christiandevito417 Good for you brotha, you did what you had to do.

    • @christiandevito417
      @christiandevito417 2 роки тому +6

      @@em34ev3r whole food plant based diet, Intermittent Fasting, exercise. Spiritual forgiveness, and supplements.

    • @cjoyler1
      @cjoyler1 2 роки тому

      @@christiandevito417 Can I ask what supplements you are taking?

    • @christiandevito417
      @christiandevito417 2 роки тому +5

      @@cjoyler1 curcumin, D3, K2, Vitamin C, beta glucan, black seed oil. Melatonin (on and off) and make a lemon garlic extract. I add aged garlic and a few other things on a rotation.

  • @Caveman1420
    @Caveman1420 Рік тому +6

    This is the most informative video yet I seen. Thank you. I seen 4 cancer doctors and the last two last week one at Duke and a Unc doctors and this video was both of them combined. I have stage 4 pancreatic cancer now I had the Whipple and chemo 2 years ago. And have LYNCH syndrome msh6, ATM, mutyh, KRAS found in my tumor they cut out. Now I am waiting on MIS testing. But they need I get a biopsy from my lungs. For that test. Can that be done with a blood biopsy. I just did one last week again. Or does it need to do a biopsy of my tumors in my lungs? I am glad I have different opinions now. Before one chemo drug that was it. Take it til I can not tolerate it or die. And a couple more months is not worth the hell Chemo puts me through. Five month ago I was told I have months I am still here and still waiting on testing finally it is here. If you have cancer do your research and try to make the best decisions possible and are available and good luck.

  • @Optunity
    @Optunity Рік тому +1

    Wow. Thank you for your work

  • @robynnepeterson3798
    @robynnepeterson3798 Рік тому +2

    Look up Thomas Seyried, Cancer being a metabolic disease.

  • @ercankalafat7948
    @ercankalafat7948 2 роки тому +5

    I think the time has come to announce a new major for MD’s, immunologist…

  • @daoyang491
    @daoyang491 2 роки тому +1

    well done presentation.

  • @josephodundo4466
    @josephodundo4466 2 роки тому +2

    Thank you very much I have cancer of the neck and head squamous cells carcinoma I hope this can help me my doctors have put me on palliative care

    • @CancerResearchInstitute
      @CancerResearchInstitute  2 роки тому

      Hi Joseph- we are sorry to hear that, but are wishing you all the best with your treatment!

  • @irmaleticiavillagranmonzon5019

    Me quedé con deseos de saber mucho más por la muerte de mi esposo saber del cáncer y los avances en las más recientes informaciones

  • @samuelezung504
    @samuelezung504 2 роки тому +5

    Hii dear cancer research center greetings from India, your video has been such a helpful for me and for my family as well.
    I have been watching videos on immunity therapy which sounds so helpful and I am very grateful for that but lately I haven't heard from this video that immunity therapy is not mentioned to cure stomach cancer (gastric) so is there any information on since I have family member who has stomach cancer on advance stage , and another question I have to ask your esteem center is can you please recommend a well trusted immunity therapy here in India if you can kindly give a proper information will be highly appreciated, thank you.
    eagerly waiting from your end.
    Sam.

    • @CancerResearchInstitute
      @CancerResearchInstitute  2 роки тому

      Hi Sam- you can learn more about stomach cancer and immunotherapy by visiting our website: www.cancerresearch.org/Immunotherapy/Cancer-Types/Stomach-Cancer

    • @peternuanbalfour-ogilvy9360
      @peternuanbalfour-ogilvy9360 Рік тому

      Lydia here using my hubby page would like you to recommend an immuno therapy for cervical cancer stage 3b if any and or other alternative

  • @valerieesteban6522
    @valerieesteban6522 2 роки тому +2

    Hi have an invasive ductal breast canser am interested how immunutherapy work or heal coldhelp mi n how could i avail when were in distant place. Could u help me dr.

    • @CancerResearchInstitute
      @CancerResearchInstitute  2 роки тому +1

      Hello Valerie, To learn more about immunotherapy treatments, and specifically immunotherapy for breast cancer, take a look at our website here: www.cancerresearch.org/immunotherapy/cancer-types/breast-cancer

  • @irmaleticiavillagranmonzon5019

    Que tarde los encontré mi esposo recién falleció por cáncer de piel era candidato a inmunoterapia pero nada pudimos hacer por varias razones como el costo y el acceso por vivir en este país

  • @Optunity
    @Optunity Рік тому +1

    Why Moderna not working on mRNA on GBM?

  • @sawmkechannel
    @sawmkechannel 2 роки тому +1

    Hi I'm melanoma patient one tumor in my 🦵and 3 lymph nodes in my groin. Now i receive a keytruda and tvec treatment. Can you please give me others ideas to protect my self not growing or not spread to my organ. Thanks you

    • @CancerResearchInstitute
      @CancerResearchInstitute  2 роки тому +1

      Hi there, As we are a nonprofit, we cannot give medical advice. We suggest speaking to your care team about the best options for you. To learn more about immunotherapy for melanoma, see our website: www.cancerresearch.org/immunotherapy/cancer-types/melanoma

  • @0Deirdre0140
    @0Deirdre0140 2 роки тому

    Would this be an option for a difficult to get at stage 2a lung cancer? Not possible radiation or bronchoscope biopsy due to proximity to aorta….

    • @CancerResearchInstitute
      @CancerResearchInstitute  2 роки тому +2

      Hello Deirdre, Immunotherapy is often a promising treatment for patients with lung cancer. We suggest patients speak with their care team regarding what works best for their individual case. For more information regarding immunotherapy treatments for specific cancer types, such as lung cancer, take a look at our website: www.cancerresearch.org/immunotherapy/cancer-types/lung-cancer

  • @Lulu-kt6gr
    @Lulu-kt6gr Рік тому +1

    What about for multiple myeloma? Would immunotherapy work for a blood cancer such as that? Dostarlimab? How close are they to an immunotherapy drug for multiple myeloma and why did they solve leukemia but not Multiple Myeloma? Thank you.

    • @CancerResearchInstitute
      @CancerResearchInstitute  Рік тому +1

      Hi Lulu, To learn more about immunotherapy for multiple myeloma, please visit our website: www.cancerresearch.org/en-us/immunotherapy/cancer-types/multiple-myeloma

  • @tanusreebanik6377
    @tanusreebanik6377 Рік тому +1

    My brother is a patient of hoskin limphoma. Immunotherapy is going on now. Cancer was detected in stage 4. Nivalumab medicine is going on. How much effective by immunotherapy ? Is it 100 percent curable?Please doctor give me a reply.

  • @spencercarpenter2147
    @spencercarpenter2147 Рік тому +2

    My mother has stage 3 pancreatic cancer and I’m really hoping immunotherapy might offer some unexplored opportunities. In the uk it seems difficult to access immunotherapy, can anyone please advise me on the best way to approach this treatment including overseas options?

    • @CancerResearchInstitute
      @CancerResearchInstitute  Рік тому

      Hello Spencer, To learn more about immunotherapy, and specifically immunotherapy treatments for pancreatic cancer, please take a look at our website: www.cancerresearch.org/immunotherapy/cancer-types/pancreatic-cancer

    • @terencekwan9082
      @terencekwan9082 Рік тому +1

      Hi Spencer, so sorry for your mother's diagnosis. My wife was also diagnosed with stage 3 pan can back in 2016 but eventually become stage 4 when it spread to her liver in 2017. She tried many regimes of chemo and radiotherapy but eventually it was a immunotherapy drug call Pembrolizumab(Keytruda) that saved her. She is in full remission since Jan 2018. One of the key factor that the drug work so well is because she has a DNA defect condition call MSI-H (Microsatelite Instability High) which predispose her to response very well to Keytruda. My advise is get your mum to do a genetic and molecular test to check if she has this defect and therefore able to use this drug. Take care and best of luck!

    • @spencercarpenter2147
      @spencercarpenter2147 Рік тому +1

      @@CancerResearchInstitute hey thanks I’ll take a look!

    • @spencercarpenter2147
      @spencercarpenter2147 Рік тому

      @@terencekwan9082 what amazing news about your wife. I’ll be sure to try what you’ve suggested. She’s currently about to attempt a procedure called nano knife which aims at destroying the tumour, it’s not a cure, more of a life extension option since it doesn’t fix the root cause of the cancer.

  • @maryamkhaliq6121
    @maryamkhaliq6121 2 роки тому +3

    hi just need to ask is it work for stage 4 lungs cancer ..

    • @CancerResearchInstitute
      @CancerResearchInstitute  2 роки тому +2

      Hello Maryam, you can learn more about immunotherapy, especially for lung cancer, on our website here: www.cancerresearch.org/immunotherapy/cancer-types/lung-cancer

    • @sarahhughes3081
      @sarahhughes3081 Рік тому

      yes, definitely

  • @celticjordan1
    @celticjordan1 2 роки тому +10

    We need better treatments. Chemo/rad is terrible. 😔

    • @leegaul2161
      @leegaul2161 2 роки тому

      Chemo is barely a step up from blood letting or leaches. In a century they'll be calling us barbaric.

  • @photoMorg
    @photoMorg 2 роки тому +1

    My brother who is 67 has Melanoma and tried immune therapy it didn't work then they tried a blend of immune therapies which is more toxic but he couldn't get through it so all he is doing is radiation to help with the pain as the cancer has spread to his ribs and colon not sure what they can do now?

    • @valmardon1183
      @valmardon1183 2 роки тому

      Has he tried long fasting? Plant based diet? Wim hof? Before chemo?

  • @user-mp7rc7cm4o
    @user-mp7rc7cm4o 9 місяців тому

    Why would I be given Steroids with my low dose chemo therapy. I have clear cell uterine carsonoma...terminal stage 4. I have outlived the 1 to 2 years I've been given. My doctor is puzzled that the cancer isn't acting aggressive as it should be. I've lived 6 yes now. I was unaware I would have to do chemo before immuno-therapy. He skirted around that with me. I haven't done chemo because he said the chemo wouldn't kill the cancer. I have 3 tumors in my left lung. The chemo is shrinking the tumors...the immuno-therapy to follow is to kill down the cancer cells.

    • @user-mp7rc7cm4o
      @user-mp7rc7cm4o 9 місяців тому

      Could you tell me which immuno-therapy treatment would be best for my cancer. I keep telling my doctor I'm in God's hands. He's a helper but not the great physician! Your bodies were made to fight off germs naturally. I do take elderberry gummies and probiotics/prebiotic faithfully to keep my immune system as healthy as possible as well as my digestive system. I'm in pancreas & kidney failure. Just my right kidney from radiation damage. Any information would be helpful. I never expected to get cancer. Now that I can breathe I'm walking more. Hard to walk/exercise when you're having trouble just breathing.

  • @robynnepeterson3798
    @robynnepeterson3798 Рік тому

    They better start with the heart because the new technology is a danger to the heart!