Love from Pakistan 💖 Tomorrow is my exam and this is the only chap I have to cover so I was thinking about reading the slides but that slides were giving me a extreme headache so I thought I should check UA-cam lectures for ease and suddenly I found this fabulous channel and your lectures Your lectures are just super helpful
@@bytesizemedthanks for this video, My mom has urinary retention after a couple pelvic surgeries and urodynamics shows detusor underactivity meaning it does contract enough to empty her bladder, she does void some but has retention. Do you think sacral nerve stimulation can help her to completely void and no more use of catheters? She is 70
Very schematic video! The hypogastric and pelvic plexi and somatic innervation of bladder are very well demonstrated. B3 receptor (and therefore, clinical correlate, mirabegron for urge incontinence) are readily concluded. Also, PMC (Barrington nucleus) and prefrontal inhibitory impulse are very well illustrated in a wonderful schematic fashion.
would like to know if communication problem between brain and internal sphincter could be the reason why even after I had T.U.R.P surgery, I still can't void my bladder ? I will initiate mictions, but will only void between 25 to 50 ml. why can I begin urinating, and then it stop after 25-50ml ???
2:07 how does the same receptor cause contraction of one muscle and relaxation of another, M3 receptors are Gq so they should cause smooth muscle contraction
Though alpha 1 and M3 receptors when stimulated both elicit their actions via Gq pathway, the alpha 1 receptor is part of the sympathetic nervous system while the M3 receptor is part of the parasympathetic nervous system hence the difference in their actions on the IUS ( which is opposite).
Doesn't the detrusor muscle remain relaxed to allow the bladder to store urine under the SNS, and then contract during urination to release urine during the PNS? It's written as "contracts for storage", which may be confusing.
Hi. Sympathetic : Relaxes detrusor, contracts internal sphincter (storage) Parasympathetic : Contracts detrusor, relaxes internal sphincter (emptying) So the "contracts for storage" that you're referring to was about the sphincter and not the detrusor. Sorry if that was confusing. I hope this helps! 😊
She referred Guyton … She Just summarised excellently what guyton tries to convey…..Very useful one…
Use gk pal which is very useful and easy to study
Love from Pakistan 💖
Tomorrow is my exam and this is the only chap I have to cover so I was thinking about reading the slides but that slides were giving me a extreme headache so I thought I should check UA-cam lectures for ease and suddenly I found this fabulous channel and your lectures
Your lectures are just super helpful
its almost gonna b 1.5 years already and i wonder how i didnt come to know of this channel . its too much to the point. great work.
Best physiology video I have ever watched ..simple and informative
Thank you so much! 😊
@@bytesizemedthanks for this video, My mom has urinary retention after a couple pelvic surgeries and urodynamics shows detusor underactivity meaning it does contract enough to empty her bladder, she does void some but has retention.
Do you think sacral nerve stimulation can help her to completely void and no more use of catheters? She is 70
That's kinda professional video I'd like to learn from every day.
Thanks, you deserve a lot.
Unbelievably to the point. Although, the views don’t indicate how great the content is!
Assalamulaikum, Sister.I am Muslim Doctors. You are really a legender.May Allah accept your good deeds
Nice work.
You converted guyton into e learning
Very well elucidated.
Very schematic video! The hypogastric and pelvic plexi and somatic innervation of bladder are very well demonstrated. B3 receptor (and therefore, clinical correlate, mirabegron for urge incontinence) are readily concluded. Also, PMC (Barrington nucleus) and prefrontal inhibitory impulse are very well illustrated in a wonderful schematic fashion.
I have an anatomy exam on monday and this is amazing!
Best physiology video ever 💯. Very helpful to understand abnormalities of micturation.
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شكرا لك على مجهودك، قناة رائعة
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Ty
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Love from Bangladesh
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would like to know if communication problem between brain and internal sphincter could be the reason why even after I had T.U.R.P surgery, I still can't void my bladder ? I will initiate mictions, but will only void between 25 to 50 ml. why can I begin urinating, and then it stop after 25-50ml ???
Turp will soon be out.. Too much complications... N not explained.. Adequately
very good
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Awesome
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Thank you for your support! Yes, I use an iPad. 😊
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Now for treatments.. For all nerves involved.. Can it Be done
If we try to stop the full bladder , it is by inhibition of parasympathetic system... right?
ponto-onuf neurons? inhibitory or excitatory? does
onuf motor neurons are normally actively maintain tone in EUS?
We want PHARMACOLOGY
There is a doubt . A LESION BETWEEN L3-S1 will cause Automatic bladder or autonomous bladder?
Dang it is good!
2:07 how does the same receptor cause contraction of one muscle and relaxation of another, M3 receptors are Gq so they should cause smooth muscle contraction
Nice
Last one I think is called urge incontinence
Nice..👍
Thank you! ☺️
I always thought alpha 1 and M3 receptors both elicit the Gq pathway.. how are they acting oppositely on the internal sphincter?
Hi! You're right. The M3 receptor should have just been on the detrusor muscle. Thanks for catching that!
Though alpha 1 and M3 receptors when stimulated both elicit their actions via Gq pathway, the alpha 1 receptor is part of the sympathetic nervous system while the M3 receptor is part of the parasympathetic nervous system hence the difference in their actions on the IUS ( which is opposite).
I don’t understand the role of Pudendal Nerve here.
Btw best Lecture ❤❤
Where can i find the Slides 🥹
and Thank you ❤❤
Is S1 not relevant here? I had a herniation on L5-S1 and now I cant feel/when the bladder is full :(
Doesn't the detrusor muscle remain relaxed to allow the bladder to store urine under the SNS, and then contract during urination to release urine during the PNS? It's written as "contracts for storage", which may be confusing.
Hi.
Sympathetic : Relaxes detrusor, contracts internal sphincter (storage)
Parasympathetic : Contracts detrusor, relaxes internal sphincter (emptying)
So the "contracts for storage" that you're referring to was about the sphincter and not the detrusor.
Sorry if that was confusing. I hope this helps! 😊
@@bytesizemed Gotchya thank you!! Great video by the way!