I'm a LMHR. My LDL went through the roof on Carnivore, it was 800. Been back on 100g Carbs per day for a year, LDL back down to 186. Added Fibre and Veggies. I need to have Carbs anyway because I lose too much weight on Carnivore. Trig/HDL 59 / 109 = 0.5413. ApoB / ApoA1 113 / 221 = 0.5113. A doctor would probably have a heart attack and want to put me on Statins. Good thing I don't have one anymore :).
My recent binging of UA-cam health videos (specifically around APOB) has actually made me hate this whole topic. A whole community of medical professionals, talking in circles. More confused now than ever.
ignore them all. just don't eat junk food, exercise and if you are a 50 year old male, get a CTA. if you are a 60 year female, get a CTA, then do that every 10 years and keep your triglycerides and LDL down with under 130g carbs a day and take a statin if you need one.
ignore everyone. stop watching. be a normal weight, dont use cocain, don't smoke, don't eat junk, get a lot of exercise but not too much, eat your fruit and veg, and have fun. know your blood pressure. high blood pressure, a sedentary life, a fat tummy, and Twinkies will kill you. Apo (a) is an important test as is cholesterol. If LDL is very high and you are not a lean mass responder you need to be treated as though you have familial hypercholesterolmia that's just a fact. If you have high (a) you are at a massively higher risk. Your triglycerides can be treated with reducing carbs to under 130 a day, and not eating junk. if you are a male who is 60 you should have a CTA and KNOW what is going on.
I totally agree with you. If you want to get an honest opinion of all this lipoprotein mumbo jumbo, look up "Dr. Malcolm Kendrick and How to kill a hypothesis."
This was a great video!!! The first I have heard about the ApoB/ApoA1 ratio. My ApoB is high and my Lp(a) is also high, but my Ca heart CT was 0. My HDL is higher 70 and my Triglycerides are 63. I was having a hard time finding any information for people who have good metabolic health and these numbers. I am scheduled to have this blood work done soon. Thank you for this video, just THANK YOU.
Good vid. Question: How time-sensitive are these lipid tests to a change in diet? Another way to ask is, how long does a particular level of any one of these particles stay in the bloodstream so they can be measured?
About 3 to 4 months for red blood cells. Could be living longer if you are meat based. Wait at least 3 months to test. No a doctor... But following many 😊
I've been carnivore/keto for about three and a half years. My recent blood work showed ApoB of about 140. I need to get the ApoA1 checked! HDL and triglycerides were perfect though.
Less than 2-i have same info, don’t remember from where. Mine is 1.81. But I could raise my HDL a bit from 65.64. My TRig is 36.35🤷♀️ Closer to 1 is best I’m sure.
My blood work is excellent, excepting my lipid panel. I did get the advanced lipid panel with inflammation, but it shows no ApoA1 metric. My ApoB is 125. My HDL is 71; my triglycerides is 111. The HDL/triglycerides ratio is okay. My APO(a) is good at 56. My HS CRP is 0.3. Is there a specific test that shows ApoA1? Yes, my total cholesterol is high at 263.
Total cholesterol is not something to be concerned about. Your triglycerides needs to be much lower, under 80 at least. I suggest going to UA-cam searching for Dr. Berry, Dr. Ovadia (heart surgeon), Dr. Nadir Ali (cardiologist) and watching their videos
1.5 years ago, I had LDL 5.5 mmol/l and I started taking Red Yeast Rice (2400 mg per day). After 3 months of supplementing it dropped to 3.2 mmol/l. My APO B/APO A-1 ratio was 0.7. Now my LDL is 7,0 mmol/l (higher than ever) HDL: 1.9 mmol/l Triglyc: 0,56 mmol/l Should I run another ApoB/Apo A-1 test? Is my 2x times higher LDL a risk factor?
My Apo b on lab test taken last week is 101. It was at 149 in November. Only thing I have changed since November is increasing fiber intake. Total cholesterol dropped from 319 to 204. Going to keep doing what I’m doing since it’s working. Carnivore (unfortunately) caused the spike in these numbers so I had to stop.
My ApoB is 186 and ApoA1 is 151 mg/dL, which calculates to a 1.23 ratio. I think I may be a LMHR, because on a carnivore diet my LDL went from 106 to 249. Pretty concerning results, although the hypothesis is on a carnivore diet with lower glycation, inflammation, and blood pressure causing arterial damage, high cholesterol is not problematic. I hope that's true. I finally got a calcium score measurement of 243 taken as my baseline this past November and hope I can persuade my doctor to schedule another one in about a year, so I can see if there's a progression of calcium or if it has stabilized on this diet.
Progression of calcium is not necessarily a bad thing. Transforming your soft, unstable plaque into a stable one (which is what calcium is supposed to do) can be protective against ruptures and, thus, helpful in avoiding MACE.
I find the whole cholesterol worrying to be silly. The things that damage cholesterol damage everything else as well with metabolic disfunction. Heart disease is caused by whatever damages the lining of the arteries at the turbulent locations and that is what needs to be paid attention to. Lower the blood pressure, that's a start.
It's a three-headed monster: atherogenic, pro-inflammatory, and pro-thrombotic. There are several clinical trials underway to see if they can come up with (yet another) pill for us to take for it, because diet/lifestyle don't seem to put a dent in Lp(a).
@@markbodine9298 "Remarkably, one-quarter of the centenarians had high Lp(a) serum levels even though they never suffered from atherosclerosis-related diseases." 1998 G. Baggio.
"Nonetheless, the apo(a) size distribution in centenarians did not entirely explain the high Lp(a) levels observed in this population. Factors other than apo(a) size, and which may be either genetic or environmental in nature, appear to contribute to the elevated plasma Lp(a) levels of our centenarian population. We conclude therefore that high plasma Lp(a) levels are compatible with longevity." 1998 article by J Thillet
If one has a high Apoa/b ratio yet has a zero calcium score (7 yrs prior) and clean cardiac cath (7 yrs prior) how does that person ascertain their risk
Calcium score only shows hard plaque. I know because I also have the calcium score test ...O, but other research and other doctors have talked about it where it only detects hard plaque, not soft plaque. It's definitely a better biomarker than the LDL and HDL
In Canada we get one ☝🏻 lifetime Apo B not sure they include LPa.🤷♀️ Does anyone know? TC 240.5 HDL 65.64 LDL 160.48 TR 36.35 44 yr old female Doctor is concerned 😅
So if you have high apoB (over 200) and low apoA (20) makes the ratio not ideal according to the study. Does that mean keto/carnivore should not be ideal for an individual?
I requested my APOB but I don't think my Dr knew how to interpret it very well. My APOB as 97 but my APOA1 was 198 - with ratio of .5. It sounds like I'm OK due to the ratio but I want to get my APOB down a bit.
Ok I am totally confused. Seems to me a high apoA1 (essentially hdl) would be better to fight off high apob(essentially ldl). I am a LMHR. TC 420, LDL 310, TRIGS 74, HDL 84, APOA1 192, APOB214. A1c 5.4, fasting insulin 3, crp-hs .6
Dr Paul mason explains it pretty well apob is a marker found on good and bad particles it's an inconclusive test by itself type c damaged LDL is much more important as is obviously your triglyceride to HDL ratio
You seem to be interchanging the use of “ApoA-1” and “HDL”. My test results show HDL, but not ApoA-1. What percentage of HDL is ApoA-1? My test results show ApoB is 155; my HDL is 51. It also shows a “large HDL” of 7734 - not sure what that represents. How can I figure out my ApoB/apoA-1 ratio using these numbers?
I'm a LMHR. My LDL went through the roof on Carnivore, it was 800. Been back on 100g Carbs per day for a year, LDL back down to 186. Added Fibre and Veggies. I need to have Carbs anyway because I lose too much weight on Carnivore. Trig/HDL 59 / 109 = 0.5413. ApoB / ApoA1 113 / 221 = 0.5113. A doctor would probably have a heart attack and want to put me on Statins. Good thing I don't have one anymore :).
Even though I have not been to a doctor since 1996 this information fascinates me!
My recent binging of UA-cam health videos (specifically around APOB) has actually made me hate this whole topic.
A whole community of medical professionals, talking in circles. More confused now than ever.
Look at the ratios of APOb to A1 ratio.
And HDL to LDL ratio.
They are important to predict a Major Adverse Cardiac Event ( MACE)
ignore them all. just don't eat junk food, exercise and if you are a 50 year old male, get a CTA. if you are a 60 year female, get a CTA, then do that every 10 years and keep your triglycerides and LDL down with under 130g carbs a day and take a statin if you need one.
ignore everyone. stop watching. be a normal weight, dont use cocain, don't smoke, don't eat junk, get a lot of exercise but not too much, eat your fruit and veg, and have fun. know your blood pressure. high blood pressure, a sedentary life, a fat tummy, and Twinkies will kill you. Apo (a) is an important test as is cholesterol. If LDL is very high and you are not a lean mass responder you need to be treated as though you have familial hypercholesterolmia that's just a fact. If you have high (a) you are at a massively higher risk. Your triglycerides can be treated with reducing carbs to under 130 a day, and not eating junk. if you are a male who is 60 you should have a CTA and KNOW what is going on.
I totally agree with you. If you want to get an honest opinion of all this lipoprotein mumbo jumbo, look up "Dr. Malcolm Kendrick and How to kill a hypothesis."
You can take a look at the UA-cam chapters of this video for a pretty good summary
This was a great video!!! The first I have heard about the ApoB/ApoA1 ratio. My ApoB is high and my Lp(a) is also high, but my Ca heart CT was 0. My HDL is higher 70 and my Triglycerides are 63. I was having a hard time finding any information for people who have good metabolic health and these numbers. I am scheduled to have this blood work done soon. Thank you for this video, just THANK YOU.
My HDL is 88 and triglycerides 45. Felling pretty good about that.
HDL and LDL are really not good biomarkers anymore. ApoB and LpA
@@bigswolletxso what if my lipoprotein (a) is 12 and my apoB is over 200? My adiponectin was good too 🤷🏼♀️.
Can anyone tell me the difference between:
Apoa1 174
Lipoprotein (a) 12
ApoB 212
Apolipoprotein B 250
I’m so confused!!
Mine was reversed of those numbers.
@ Did you miss the part at the end where he said HDL/trig ratios are a good substitute for Apo numbers?
thanks. very clear and brief.
Great information and thank you 😊 I plan to request this test❤
Good vid. Question: How time-sensitive are these lipid tests to a change in diet? Another way to ask is, how long does a particular level of any one of these particles stay in the bloodstream so they can be measured?
About 3 to 4 months for red blood cells. Could be living longer if you are meat based. Wait at least 3 months to test. No a doctor...
But following many 😊
I've been carnivore/keto for about three and a half years. My recent blood work showed ApoB of about 140. I need to get the ApoA1 checked! HDL and triglycerides were perfect though.
Looks at numbers...😳 How am I still alive?
Thanks Mike. Good talk.
I thought HDL was supposed to be twice Triglycerides. Don't remember who said it.
triglycerides have their own measure, HDL is the only non atherogenic measure so you can't measure one against another. triglycerides are atherogenic.
Less than 2-i have same info, don’t remember from where. Mine is 1.81. But I could raise my HDL a bit from 65.64. My TRig is 36.35🤷♀️ Closer to 1 is best I’m sure.
My HDL gets flagged and analyzed twice on every blood test. It's 147 this time and 151 the time before. Who knows, I don't.
My blood work is excellent, excepting my lipid panel. I did get the advanced lipid panel with inflammation, but it shows no ApoA1 metric. My ApoB is 125. My HDL is 71; my triglycerides is 111. The HDL/triglycerides ratio is okay. My APO(a) is good at 56. My HS CRP is 0.3. Is there a specific test that shows ApoA1? Yes, my total cholesterol is high at 263.
Total cholesterol is not something to be concerned about. Your triglycerides needs to be much lower, under 80 at least. I suggest going to UA-cam searching for Dr. Berry, Dr. Ovadia (heart surgeon), Dr. Nadir Ali (cardiologist) and watching their videos
1.5 years ago, I had LDL 5.5 mmol/l and I started taking Red Yeast Rice (2400 mg per day).
After 3 months of supplementing it dropped to 3.2 mmol/l. My APO B/APO A-1 ratio was 0.7.
Now my LDL is 7,0 mmol/l (higher than ever)
HDL: 1.9 mmol/l
Triglyc: 0,56 mmol/l
Should I run another ApoB/Apo A-1 test? Is my 2x times higher LDL a risk factor?
My ApoB came back as normal.
I am a LMHR.
My LDL is 240 and my trigs are 40 and my HDL is 114.
What's your ApoB to ApoA-1 ratio?
My Apo b on lab test taken last week is 101. It was at 149 in November. Only thing I have changed since November is increasing fiber intake. Total cholesterol dropped from 319 to 204. Going to keep doing what I’m doing since it’s working. Carnivore (unfortunately) caused the spike in these numbers so I had to stop.
My ApoB is 186 and ApoA1 is 151 mg/dL, which calculates to a 1.23 ratio. I think I may be a LMHR, because on a carnivore diet my LDL went from 106 to 249. Pretty concerning results, although the hypothesis is on a carnivore diet with lower glycation, inflammation, and blood pressure causing arterial damage, high cholesterol is not problematic. I hope that's true. I finally got a calcium score measurement of 243 taken as my baseline this past November and hope I can persuade my doctor to schedule another one in about a year, so I can see if there's a progression of calcium or if it has stabilized on this diet.
Progression of calcium is not necessarily a bad thing. Transforming your soft, unstable plaque into a stable one (which is what calcium is supposed to do) can be protective against ruptures and, thus, helpful in avoiding MACE.
If you don't know your apoB and apoA1 numbers but you do know your Triglycerides and HDL, what would be the ideal Triglycerides/HDL ratio?
I find the whole cholesterol worrying to be silly. The things that damage cholesterol damage everything else as well with metabolic disfunction. Heart disease is caused by whatever damages the lining of the arteries at the turbulent locations and that is what needs to be paid attention to. Lower the blood pressure, that's a start.
What are your thoughts on Lp(a)?
It's a three-headed monster: atherogenic, pro-inflammatory, and pro-thrombotic. There are several clinical trials underway to see if they can come up with (yet another) pill for us to take for it, because diet/lifestyle don't seem to put a dent in Lp(a).
@@markbodine9298 I've read the PCSK9 inhibitors can reduce it, but I'm not sure I want to go down that path..
@@markbodine9298 "Remarkably, one-quarter of the centenarians had high Lp(a) serum levels even though they never suffered from atherosclerosis-related diseases." 1998 G. Baggio.
"Nonetheless, the apo(a) size distribution in centenarians did not entirely explain the high Lp(a) levels observed in this population. Factors other than apo(a) size, and which may be either genetic or environmental in nature, appear to contribute to the elevated plasma Lp(a) levels of our centenarian population. We conclude therefore that high plasma Lp(a) levels are compatible with longevity." 1998 article by J Thillet
If one has a high Apoa/b ratio yet has a zero calcium score (7 yrs prior) and clean cardiac cath (7 yrs prior) how does that person ascertain their risk
Calcium score only shows hard plaque. I know because I also have the calcium score test ...O, but other research and other doctors have talked about it where it only detects hard plaque, not soft plaque. It's definitely a better biomarker than the LDL and HDL
Get a CIMT.
What's a CMIT @DK-pr9ny
In Canada we get one ☝🏻 lifetime Apo B not sure they include LPa.🤷♀️ Does anyone know?
TC 240.5
HDL 65.64
LDL 160.48
TR 36.35
44 yr old female
Doctor is concerned 😅
So if you have high apoB (over 200) and low apoA (20) makes the ratio not ideal according to the study. Does that mean keto/carnivore should not be ideal for an individual?
My ApoB/ApoA1: 0.73
I requested my APOB but I don't think my Dr knew how to interpret it very well. My APOB as 97 but my APOA1 was 198 - with ratio of .5. It sounds like I'm OK due to the ratio but I want to get my APOB down a bit.
Ok I am totally confused. Seems to me a high apoA1 (essentially hdl) would be better to fight off high apob(essentially ldl). I am a LMHR. TC 420, LDL 310, TRIGS 74, HDL 84, APOA1 192, APOB214. A1c 5.4, fasting insulin 3, crp-hs .6
APOB 214??! Holy smokes!
Where are getting apo b for $17? Quest charges $172
Try Ownyourlabs(labCore) maybe they have better pricing.
Ultalabs has Apo B for $35.95. Also Apo A and B for $55.95 (and that is a quest lab draw)
💪🏿💪🏿
Can anyone tell me the difference between:
Apoa1 174
Lipoprotein (a) 12
ApoB 212
Apolipoprotein B 250
I’m so confused!!
Me too!
@ of course no one responded 🤷🏼♀️
LPa is 36.3 and ApoB is 140. What’s the ratio?
3.8. High risk category
Lpa 36 is normal, which is good. Lpa is not ApoA, you need to have ApoA to calculate the ratio.
I liken prescribing statins to defunding the fire department.
Dr Paul mason explains it pretty well apob is a marker found on good and bad particles it's an inconclusive test by itself type c damaged LDL is much more important as is obviously your triglyceride to HDL ratio
Agreed . Besides an NMR panel to distinguish the LDL particle sizes , ox-ldl is also a good indicator of inflammation
£90 in uk, rip off Britain as usual
CAC about £400 and needs a docs referral....arsehole of a country!
You seem to be interchanging the use of “ApoA-1” and “HDL”. My test results show HDL, but not ApoA-1. What percentage of HDL is ApoA-1? My test results show ApoB is 155; my HDL is 51. It also shows a “large HDL” of 7734 - not sure what that represents. How can I figure out my ApoB/apoA-1 ratio using these numbers?
ua-cam.com/video/LiFDvyGi_7M/v-deo.htmlsi=o4aCuw_SB0aEBOlX
Apob track with ldl…you would have to lower either of high. Might as well try to lower saturated fat.
Saturated fat is good for you....study up
Another potential victim for Bart Kay.
Chatgpt says to lower saturated fat to improve Apo B. Not saying I'm agreeing with it but, it is something to think about.