Acute Disseminated Encephalomyelitis | ADEM

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  • Опубліковано 25 жов 2024

КОМЕНТАРІ • 131

  • @alexanderkraemer5958
    @alexanderkraemer5958 3 роки тому +19

    My 9 yr old daughter got this in September of 2019 after receiving an ear infection. Nobody knew what was going on as her condition worsened. She exhibited nearly all the symptoms you discussed. It was a very scary time for us as the doctors didn't know what was going on. She was hospitalized to 8 days, 3 of which in the ICU. THANKFULLY Dr. Vinay Puri saved her. He walked into her room, looked at her for 5 minutes and diagnosed her on the spot. Put her on 800mg of steroids per day and by the next day, she woke up for the first time in 4 days. It was only for 15 minutes, but it was enough to give us hope that she was going to pull through. Thank you for this video, even though I am no doctor, but it definitely helped me understand what went on with her that day.

    • @knickerbockers2010
      @knickerbockers2010 5 місяців тому

      did she recover ? did she use imunoglobulin after ?

  • @ttocselbag5054
    @ttocselbag5054 3 роки тому +11

    I watch Zach only incrementally, but each time I do, I become intoxicated with fascination and massive appreciation! Thank you good sir for your willingness to share your massive brain power!! 😊

  • @chrisaguilera1564
    @chrisaguilera1564 3 роки тому +29

    I wish I had a professor like him in any of my courses in college. Probably would have retained most of it.

  • @AshleyDavis-i2t
    @AshleyDavis-i2t 8 місяців тому +3

    My son was diagnosed with ADEM at 2 years old, his last vx was in March 2022, his ADEM episode was in October 2022. After all of the labs he was only positive for rhinovirus. He presented with fever, decreased LOC, Dysphonia, Dysarthria, and seizures. He had a lumbar tap after his MRI to ensure they could start the IV steriods and the CSF came back clear and was MOG negative and MRI did show ADEM with two lesions in his frontal lobe. after the IV steroids for 5 days he spent the next 8 months in PT OT and ST. He has made a full recovery, I wish there was more information on ADEM, but I just wanted to make other aware that ADEM can also be cause by a simple common cold like my son.

    • @knickerbockers2010
      @knickerbockers2010 5 місяців тому

      what does it mean "8 months pt ot st ? my son stopped today corticosteroid therapy of 5 days, he cant still walk normally, but he eats alone and speaks well. did you use immunoglobina ?

  • @sarah106100
    @sarah106100 Рік тому +2

    It’s nice to see more information available now. I had ADEM when I was 15, 38 year’s ago, it took the doctors 3 weeks to finally diagnose me with ADEM. I’m still suffering with the after effects. Hugs to anyone going through this horrible illness ❤

    • @jcsabali9733
      @jcsabali9733 9 місяців тому

      Hi Sarah. My daughter, who is 25, is going through this now. She is currently being diagnosed with MOG. Her symptoms showed in Sept of ‘23. It was treated with high dose of steroids and she got better. But now, January of ‘24, she showed new lesions and her neurologist wants to do the IVIG, which we are currently going through. Her original symptoms back in Sept. where speech slur and motor skills issues. The current symptoms are minimal, but noticeable, speech slurs. I have her on a 99% plant based diet avoiding high sugars and red meat. Hopefully all works out and I can share her journey to help others. I am considering going to the Mayo Clinic in Minnesota, which has a MOGAD center. I am open for any questions anyone has. I want to help out as much as possible.

    • @ivanavelickovska2748
      @ivanavelickovska2748 Місяць тому

      ​​@@jcsabali9733how was she diagnosed with MOG?

    • @jcsabali9733
      @jcsabali9733 Місяць тому

      @@ivanavelickovska2748 they did a spine tap, blood work and mri in the spine and brain. MRIs showed lesions. She is now doing IVIG 1x month and she is doing good

  • @hammerradiology1470
    @hammerradiology1470 3 роки тому +4

    I get lost in pathophysiology quite often so it's nice to see you explain it so well...thanks!

  • @yaboicraig5969
    @yaboicraig5969 2 роки тому +7

    I caught covid in October and I developed this. I was in the hospital for almost a month. Im still dealing with some after effects and got told I got really lucky. I lost the use of my right arm and and leg and my left arm and leg just feels hot all the time. Im 29 and didnt know how rare it was and hopefully things get better with time and medication. This was very informative!

    • @xxxspongebobxxxk
      @xxxspongebobxxxk 2 роки тому

      Hi! Thank you for sharing. I caught covid in December and I also developed this. I was in the hospital for 7 days, and I just got home yesterday. Thinking I came home too early.. I am also 29 and it’s scary as hell. I’m always dizzy and I started losing my vision. I’m glad you’re feeling better and I wish you the best. Thank you for making me feel less alone in this. ❤️‍🩹

    • @MrShock8
      @MrShock8 2 роки тому +1

      @@xxxspongebobxxxk may i ask if you we’re vaccinated at the time of your symptoms?

    • @xxxspongebobxxxk
      @xxxspongebobxxxk 2 роки тому +1

      @@MrShock8 I got fully vaccinated in July 2021. Covid symptoms in December were mild; developed ADEM late last month.

    • @xxxspongebobxxxk
      @xxxspongebobxxxk 2 роки тому +2

      Hello again. If you ever see this, I hope you’re doing well. I don’t have ADEM. I have MS. And I just wanted to clarify. Your comment and this video were very helpful for me. Thank you.

    • @shujahussain1104
      @shujahussain1104 Рік тому +1

      @@xxxspongebobxxxk hey! Hope you're doing well. I just wanted to share that I also suffered from ADEM and the symptoms developed after 15 days from taking first dose of covid Vaccination. I guess this covid or the vaccine has something to do about this. My both legs were fully collapsed at that time, but by the grace of God I'm fine now, back on my feet. I still have some symptoms like neurogenic bladder and a temperature sensation problem. Please do reply with what your thoughts about this. You are not alone in this. ❤

  • @dangereese9545
    @dangereese9545 Рік тому +1

    I’m 31 and just got out of the hospital for this. Thank you for the content. I may not be the typical patient but this was very informative and gives me and understanding of how it may have happened to me.

    • @jisoob5318
      @jisoob5318 7 місяців тому

      Did you cure? , Be well💔

  • @teanainternetima
    @teanainternetima 2 роки тому +2

    Hi, I'm a med student from Croatia, and in Europe, among guidelines to differentiate between ADEM and MS actually says that ADEM has little to no oligoclonal antibodies in the CSF. I am not certain if that difference applies only in Europe, but if you are a med student from this side of the world, it may be helpful to take that into account! Despite that minor difference, this is a great and very informative video, so thank you very much for posting it! 🥰🥰

  • @claire777.
    @claire777. 3 роки тому +4

    Thank you for this. My doctors didn’t explain anything about ADEM to me after I was diagnosed.

  • @DocMaan21
    @DocMaan21 3 роки тому +6

    Just sat studying! On time ❤️

  • @Diego-ji6ep
    @Diego-ji6ep 3 роки тому +4

    Thank you Ninjas! I have a seminar about ADEM next week, it will help me a lot

  • @andreasanreiter4975
    @andreasanreiter4975 9 місяців тому +1

    Thank you for providing these videos!

  • @francescaitta4775
    @francescaitta4775 8 місяців тому +1

    Amazing, as always. Thank you for the video.

  • @davidkuledjawa8447
    @davidkuledjawa8447 3 роки тому +2

    Ninja nerd is always the best. Keep the 🔥🔥🔥 burning

  • @annistonreeves9374
    @annistonreeves9374 2 роки тому +1

    In 2018 I got ADEM from mono! I was in the hospital for a month and I was also diagnosed with spinal meningitis, and PRES.

  • @m.imrankhan7954
    @m.imrankhan7954 3 роки тому +1

    Dear sir I am your regular students I have watched many lecture really I like it

  • @doctoranwar980
    @doctoranwar980 2 роки тому +1

    Perfect explanations … Perfect professor isA

  • @etoil4693
    @etoil4693 3 роки тому +1

    awesome! You are without any doubts the best!

  • @ridiculouslyshort
    @ridiculouslyshort 2 роки тому +2

    I had adem 2 years ago and was put on IVIG and cyclophosphamide in hospital, I was only 26, I'm still undergoing rehab but my dad was told it was MS until my drs got my mri back

  • @txelmore
    @txelmore 3 роки тому +6

    I got hit pretty hard with ADEM 25 years ago when I was 29 and am still dealing with the after effects. It’s quite a disease.

    • @claire777.
      @claire777. 3 роки тому +2

      I’m so sorry that happened. I’m currently recovering. If you don’t mind, what were the lasting effects? I just want to know what to expect.

    • @txelmore
      @txelmore 3 роки тому +5

      @@claire777. thanks for your empathy, and I too am sorry for what you are going through. As you are aware ADEM is different for everyone, but similar in many ways as it tends to strike the same areas. When I was hit it was quick and powerful, from my first noticeable symptoms (numbness in right arm and slurred speech) to hospitalization within three days. I was completely blind, unable to speak or reason, and my right side was paralyzed. Eye sight returned in a week or so, paralysis maybe two weeks or less (still list to right when walking), and speech was the slowest to return (three or four months of therapy).
      Lasting effects:
      Fatigue is the biggest. I have to get at least 8 hrs or I’m really no good to anyone. Fatigue can last a few days or more. It comes on for no apparent reason, but I am sure I have overdone it and just didn’t realize. Once I have, all other symptoms become exacerbated. I lose train of thought easily, search for words and forget names quite often.
      It seems my good time of the day is between 11:00 am and 6:00 pm. It is during those time I operate most effectively, this is not to say that outside of those times I can’t function.
      To look at me it is quite deceiving that I am disabled and I keep it that way. I eat healthy and exercise. I have learned my body and how I can best handle this disease. It is important that you do the same, and I’m sure you will. I hope this helped, and ask me anything you want to know.

    • @rohangore1730
      @rohangore1730 Рік тому

      Hi

    • @TamkinSpice
      @TamkinSpice Рік тому

      My cousin is still comatose with ADEM she’s only 18

    • @txelmore
      @txelmore Рік тому

      @@TamkinSpice she is in my prayers!

  • @ifigeniakrania4642
    @ifigeniakrania4642 3 роки тому +2

    Thank you for this video. Immensely helpful!

  • @HannahQuinlan-j4g
    @HannahQuinlan-j4g Рік тому +1

    I am a 35yr old female and was diagnosed with ADEM after presenting with lhermittes sign. This was all, post viral meningitis. I wasn't treated for the ADEM and 5 months later am having symptoms you talked about. Is it too late to treat now? Thanks for a very informative video

  • @Mkhan-tl3yx
    @Mkhan-tl3yx 24 дні тому

    So precise outstanding

  • @martinford76
    @martinford76 7 місяців тому

    Thanks for this content Ninja Nerd i have used it for personal health study in recommendation to my GP and Neuropsychologist along with other research regarding my Subjective Objective signs and symptoms post TBI inc post vaccinations in helping diagnosis and clarification of EEG I had also in regards to the physical brain injury and related diagnosis.

  • @Md76iran
    @Md76iran Рік тому

    You are fantastic thank you very much
    Medical students from iran

  • @dranatomy786
    @dranatomy786 3 роки тому +1

    Great explanation. Job well done.

  • @themotivation8998
    @themotivation8998 3 роки тому +2

    Just amazing dude

  • @desimedicos8425
    @desimedicos8425 3 роки тому +1

    My favorite 😍 ninja nerd 🤗

  • @ahmedlotfy7814
    @ahmedlotfy7814 3 роки тому

    Greetings from Egypt, Ninja. I like your videos a lot

  • @mio0101
    @mio0101 4 місяці тому

    Thank you so much!!

  • @drabdirahmanibrahin6021
    @drabdirahmanibrahin6021 3 роки тому +2

    Thanks

  • @RochelleVanWey
    @RochelleVanWey 7 місяців тому

    I had got this 7 years ago and am still fighting it. I am almost completely healed. I had also got COVID 19, but that lasted only 1 week.

  • @ophthalmology9889
    @ophthalmology9889 2 роки тому

    Thank you for sharing

  • @barbaramorris5636
    @barbaramorris5636 2 роки тому

    Such a good explanation to what I have. X

  • @sbatou87
    @sbatou87 19 днів тому

    Supposedly, this is what I had back in '06. As far as I can remember, they put it down the root cause to a viral infection, but didn't know which virus it was. I'm still affected by it (permanent scarring at least my left occipital lobe).

  • @jjj5918
    @jjj5918 3 роки тому +1

    Ninja Nerd, it would be great if you created a video on ADEs.

  • @dustin9893
    @dustin9893 Рік тому

    I've never been so sad in my life. 3 years ago I was diagnosed with Adem. My legs are paralyzed now and I just can't accept that they are. I feeling like my life's been takin from me. It's caused me so much depression

    • @annettebarker2078
      @annettebarker2078 6 місяців тому

      Praying for you. Hang in there. I hope you have a good therapist.

  • @PMHNP101
    @PMHNP101 3 роки тому +1

    Great video! Thank you!. :)

  • @narenderkumar933
    @narenderkumar933 3 роки тому

    Thank you soooooo muuuuccchhh it was too good

  • @axellaskri2940
    @axellaskri2940 Рік тому +3

    hello sir.
    My name is axel, 24 years old from Algeria. im 2018 i went to dentist to fix my teeth then went home after probably a week i started feeling numbness in my hand, troubles speaking, and diplopia. the the symptomes relieved without any meds, after almost 8 months i started having symptoms like lost in balance, troubles speaking clearly, diplopia again, and lost in taste and smell. i went to many doctors and they requested an MRI on my brain and spinal chord. the MRIs showed that i have demyelinating lesions on both spinal chord and CNS, been through a spinal tab and the IGg index was positive awell, and in the serology test i ve found that i have been infected of with HBV and the viral load was extremely high 9.42 log. i started taking the antivirals, and continued my diagnosis for the brain infection, been through a second spinal tab for HBV serology of Celebro spinal fluid and the results were positive after a year if research i have been diagnosed with MS and stared taking interferons which i couldnt handle. stopped it under doc's supervision and now am back on it since theres no alternative and no much meds here in Algeria
    now i have two questions if u may
    - can the hbv cross the bbb ?
    - did the hbv trigger my brain dymelination?
    i ve been searching lately and i found this article about ADEM, and started wondering whether i might mistakenly diagnosed.
    i would really pleased if answer, am so lost and cant find answers to my case.
    thank you so much.

  • @sirifarstad9396
    @sirifarstad9396 4 місяці тому

    Hi, thank you for this. What is your background? Medical Dr or otherwise? Thanks

  • @timothydavis2568
    @timothydavis2568 8 місяців тому

    Great video! Im wondering what to do as someone who previously had ADEM, and is trying to recover from the nerve damage/improve nerve function. Is it possible to recover the myelin sheath?

  • @jeje2538
    @jeje2538 2 роки тому

    Thank you so much 🌹🌹

  • @m_m786
    @m_m786 3 роки тому +1

    Great ❤️👏🩺

  • @bella-yn6oy
    @bella-yn6oy 3 роки тому

    great workk

  • @masihahmadi3653
    @masihahmadi3653 3 роки тому

    great video!

  • @fashionmixtapes
    @fashionmixtapes 2 роки тому +1

    you are a legend. This is likely what I've got after being vaxassinated. Watched 5000 videos and looks pretty close. Going to try and privately get the plasmapheresis or IVIG

  • @saralissali1090
    @saralissali1090 3 роки тому

    Can you make a video about chronic pancreatitis

  • @husseinghazi107
    @husseinghazi107 3 роки тому

    Great man..

  • @jeje4164
    @jeje4164 2 роки тому

    Thanks alot

  • @江冠霖-s2y
    @江冠霖-s2y Рік тому

    thank you so so so much (:

  • @Starliner.
    @Starliner. 3 роки тому

    Okay so you prescribe ABX and Anti virals but what about anti fungal? Is fungal meningitis ruled out because of the CSF not containing glucose? Also love the content keep it up!!!

  • @proteinkinasea2314
    @proteinkinasea2314 Рік тому

    may I ask can someone briefly describe the mechanisms of autoimmune disease? I searched that other than molecular mimicry, there are 'Dual TCRs' and 'Chimeric TCR', can someone briefly introduce or explain for me? Thank you very much

  • @Christknight1991
    @Christknight1991 11 місяців тому

    I had it when I was four had to learn all motor functions

  • @CDNMusicLover
    @CDNMusicLover 2 роки тому

    10yrs old one eye went blind, spread to both in a week. Hospitalized 3 months. One eye almost blind and other needs glasses. ADEM.

  • @srinivas3241
    @srinivas3241 Рік тому

    Why Anti-MOG antibodies not mentioned?

  • @saramahdavi906
    @saramahdavi906 3 роки тому

    Awesome😍

  • @wassimzurba3254
    @wassimzurba3254 3 роки тому

    Beautiful 🤩

  • @gustavs495
    @gustavs495 3 роки тому

    Thanks Prof God bless you

  • @saifhady8514
    @saifhady8514 7 місяців тому

    U r great

  • @knickerbockers2010
    @knickerbockers2010 5 місяців тому

    Does anyone has experience with combination of therapy of metilprednizolon and immunoglobin ??? my 8 year old son stopped today metilprrednizolon inkection and 8 days he is in intesive care and still not on feet. I am wondering if imunoglobulin would work here and now

  • @DrChaitanya.S
    @DrChaitanya.S 3 роки тому

    Awesome

  • @tazmeenfatima6721
    @tazmeenfatima6721 Рік тому

    Lovely

  • @robrobertson6780
    @robrobertson6780 3 роки тому

    Love you all

  • @keti6462
    @keti6462 2 роки тому

    the besttt

  • @rochellelendermon5012
    @rochellelendermon5012 Рік тому

    I have that disease. Nobody knows how it happens and I have it for 6 years and it is now almost completely gone.

  • @tomaspin9
    @tomaspin9 3 роки тому +2

    This is the aggresive sister of multiple esclerosis

  • @stoms8238
    @stoms8238 Рік тому

    I’m screwed. Most of these symptoms. I wish I got onto the brain swelling in the first place. Altered mental status T2 Flairs.

  • @thehousemom872
    @thehousemom872 3 роки тому +1

    ❤❤❤❤ love it

  • @cheetaraneenja2465
    @cheetaraneenja2465 4 місяці тому

    they think my freind has it and she is 45....I hear that is not common?? could years of drug abuse with prescription drugs (the most)and legal ones contribute towards this?

  • @dannyoh5219
    @dannyoh5219 3 роки тому

    I study something completely different, but I'm still watching lol

  • @sharonsanderson4514
    @sharonsanderson4514 Рік тому

    Absolutely positively cannot use contrast dyes . My body will not accept it even with the CSF long story about the operating room the doctor himself had to jump like a frog I knew beforehand I was not scared I was terrified because of the contract how to use on me. My mother flatline three times in the 70s we were told never to use any contrast dye on the immediate family he started it but he didn't finish it but I have no idea because they never gave me no explanation of what I'd started to CSF or what happened in the operating room all I know is he had to incubate me his self because anesthesiologist freaked out. But that surgeon never talk to me after the surgery and never answered any questions on how the CSF started so I have no reasoning to pass it on the other doctors on did it start because I had a tooth start as a bacterial infection or a cephalitis I don't have no idea and probably never will because holding back of information. Something's been hidden for a reason. I might be down but I'm not stupid

  • @maryjohann9491
    @maryjohann9491 3 роки тому

    Is there possibility to survive in this kind of disease?

    • @presdice6046
      @presdice6046 Рік тому

      Yeah. Adem is curable. It attacks once but Ms attacks several times

    • @archibaldplum5171
      @archibaldplum5171 Рік тому

      Most people (~95%) survive ADEM. The problem is that it often leaves scars on the CNS, meaning permanent disability or cognitive problems.

    • @maryjohann9491
      @maryjohann9491 Рік тому

      My sister passed away after 3 weeks she was confined, too fast

    • @sarpsays
      @sarpsays 18 днів тому

      The mortality rate can be as high as 5%-10%. The rate of permanent disabilities from minor to major are up to 60-70%. So the chance of true full recovery really is closer to at most 30%.

  • @sharonsanderson4514
    @sharonsanderson4514 Рік тому

    Would you like a sample of my blood? I have a suspicion that you made find something very interesting pertaining to this subject.😅 In my situation I'm gasping for air I have attended be one of these people that are overlooked because of the rarities. And when it comes to diagnosis I would say I fall into the extremely rare category. And most the time told it's all in my head and I need to chill.
    Although when an instance it came that I self diagnosed myself for the CSF in 2021 my primary care doctor said she'd only ever seen two in her lifetime 32 years of practice and I was the second one it took me at least a year to make sure what I was looking at was in fact a CSF and it took her a few minutes in the office before I can convince her I didn't want to feel that I was playing LeapFrog but I had to let her know that I didn't have allergies that already been tested for allergies over a year prior to bcsf revealing itself. When my primary care doctor is very good doctor after ice squeezed the brain fluid out of tissue that was in my nose onto my light grey t-shirt with turned it dark gray her eyes got big as saucers and she said something's not right I said I think it's a CSF she said you know what I think you're right we're going to get you seats you're scared to the and she hit the ground running by that time I was relieved but still I was scared to death. And that's not worrying I'm sitting here right now my hands going numb and my head feels like it's crawling your has an infection. No answers so I have to seek these myself unless it is that they do private studies on people to see how long things will last I don't approve being a guinea pig whatsoever.??????????😢

  • @abdikariimmohammedahmed3883
    @abdikariimmohammedahmed3883 3 роки тому +1

    Ninja nerd

  • @pamagujar183
    @pamagujar183 3 роки тому +1

    Can Herpes Simplex be added to the causation?

  • @BobbiJW2512
    @BobbiJW2512 3 роки тому

    Oh my god

  • @prernasharma4951
    @prernasharma4951 Місяць тому

    👏

  • @johninman6039
    @johninman6039 3 роки тому +1

    Believe me none of this is interesting, it is devastating when you get it at 50 years old and continue to get worse for more than a year with no help in sight.

  • @أمانيخليلعمرعبد

    ❤❤

  • @kavilavano4433
    @kavilavano4433 2 роки тому

    THIS MAN IS THE REENCARNATION OF DA VINCI

  • @sandeepshankar3254
    @sandeepshankar3254 Рік тому

    Osum

  • @edmonduku9330
    @edmonduku9330 3 роки тому

    ❤️❤️❤️🙏

  • @dr.muhammadkamran5847
    @dr.muhammadkamran5847 Рік тому

    ❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤

  • @umedic
    @umedic 3 роки тому

    Comment for yt algorithm

  • @talevskablagica7540
    @talevskablagica7540 2 роки тому

    Dajte prevod na srpski nisto ne razbraf pozdrav od makedonija

  • @mwizanyimbiri2253
    @mwizanyimbiri2253 3 роки тому +1

    👏👏👏👏👍👍👍👍😀😀💕

  • @sharonsanderson4514
    @sharonsanderson4514 Рік тому

    Steroids cannot take I'm up shits creek and going down fast 😢

  • @maria-larisahohan9502
    @maria-larisahohan9502 2 місяці тому

    ..

  • @maria-larisahohan9502
    @maria-larisahohan9502 2 місяці тому

    .

  • @plethoraplenty
    @plethoraplenty 2 роки тому +2

    I got ADEM from a vaccine.

    • @stoms8238
      @stoms8238 Рік тому +1

      I believe you i’m going thru the same thing