Titration of Amino Acids - pH, pKa1 and pKa2 - Isoelectric Point- Amino Acids (Part 4)

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  • Опубліковано 4 лют 2025

КОМЕНТАРІ • 217

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Рік тому +6

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  • @ChloeReeves-q7b
    @ChloeReeves-q7b Рік тому +129

    I specifically needed the part where he said, "shut up. It's easy." Thank you.

  • @pi6759
    @pi6759 2 роки тому +64

    whomever you are, you are a genius and blessing to us all. Thank you for explaining this in 5mins and my professor could not in 5 classes

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    @josefranciscojimenezfermin3552 3 роки тому +85

    Gotta say this: thank u so much. You just cure my depression

  • @HappyGurl4rmNY
    @HappyGurl4rmNY Рік тому +19

    OMG!!! I have been trying for YEARS to understand this concept and in one video I finally got it!!!!! THANK YOU. THANK YOU. THANK YOU.

  • @venusz6134
    @venusz6134 2 роки тому +61

    Dang how did I just find your channel! I'm self-studying the MCAT and the biochem is so discouraging since I have not taken the course. I was just talking to a friend yesterday how I wished I had some help/guidance on the subject. A teacher who can not only teach the content but also enable the students to absorb the knowledge and make connections and make sense of all the chemical reactions happing in the head as we learn. And YOU ARE IT!! Thank you Thank you Thank you!!

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    @kenda7998 7 місяців тому +8

    for the first time in my entire life i’m having fun studying biochem! you just saved my life

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  7 місяців тому +1

      I am so delighted to hear that! I hope you enjoy the rest of my Biochemistry playlist: ua-cam.com/play/PLYcLrRDaR8_dKo6Nu1Dw1efJGkDpuZGEy.html&si=COyGNznpVPedpf-I

  • @tiff-amberpaz6484
    @tiff-amberpaz6484 2 роки тому +58

    Can I just say that the "Shut uppppp" really helped my mind from drifting LOL thanks for the great video!!!!!

  • @orlandoguerrero4549
    @orlandoguerrero4549 2 роки тому +19

    You are a lifesaver!! Thank you for these videos, it makes biochemistry look easy. 😊

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 роки тому +1

      You’re very welcome 😊
      If you want more biochemistry and biology videos, checkout their corresponding playlists on my channel!

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    @yasirquershi3070 2 роки тому +8

    u have a very good style of teaching.....modulation of voice and completeness of information r key takeaways....

  • @yannychiou282
    @yannychiou282 Рік тому +2

    Hey medicosis, I’m just half way through this video and I just wanna express how much grateful I am that you’re teaching all of us on UA-cam, you’ve really helped me with tons of exams. I even went to a special cram school for my big exam and what the biochemistry teacher said I just couldn’t understand! It was so frustrating and now everything is coming clear as I go through your videos! Thank you medicosis!! Ilysm ❤

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Рік тому +1

      I am honored! You have no idea how happy I am to reach this! Thank you for putting a smile on my face! I wish you all the success in the world!

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      @yannychiou282 Рік тому +1

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    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  8 місяців тому

      @@yannychiou282Thank you, dear!

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    @gabesim4077 11 місяців тому +2

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    @sundasshareef8691 Рік тому +3

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    @Braylude 5 місяців тому +3

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    @martinmusonda3157 2 роки тому +9

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  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Рік тому +3

    😉 There’s a continuation to this BIOCHEMISTRY playlist: ua-cam.com/play/PLYcLrRDaR8_c2LBpF_OYvwijOok7ae96N.html

  • @hannahdiaz-osman5147
    @hannahdiaz-osman5147 2 роки тому +9

    You are amazing !!!! Thank you so much for putting the time and effort to make these videos, you simplified everything so much and gave me so much confidence in this subject , which I neverrrr had before !!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 роки тому +1

      I appreciate you so much!
      I have an entire “Biochemistry” playlist on my channel. I hope you find it useful!

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  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Рік тому +1

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  • @coey6744
    @coey6744 2 роки тому +3

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    @lekanganambela5183 Рік тому +3

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    @valentinacarreno1254 7 місяців тому +2

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    @MedicosisPerfectionalis  3 роки тому +4

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    @babinathulungrai6848 2 роки тому +3

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  • @daniranggg
    @daniranggg 4 місяці тому +1

    this section made me cry, not because it's hard or I did not understood but because I FINALLY understood 😭sitting from 1pm-5pm through this discussion was a nightmare, i was struggling to keep up trying to understand 😭 it's currently 2AM in my country upon writing this, I am beat and tired but after watching this I was hyped because holy crap I finally understood why, how, what for- I seriously can't thank you enough 😭😭😭 you saved this struggling medical student a lot of time and energy

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    @CindyChou-h7w Рік тому +1

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    @hieunguyen-uh6pg 4 місяці тому +1

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    @islamicsouls_ Рік тому +1

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  • @Empress426
    @Empress426 3 роки тому +6

    Thank you for giving me some clarity on this, my University made biochem self-taught, online this semester and it's giving me hell but I MUST do well. Thank you!

  • @inayat8503
    @inayat8503 Рік тому +2

    Such a nice explanation❤❤👏🏻👏🏻thank you for the video

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    @leahm3842 2 роки тому +5

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  • @cristianlopezchavez7100
    @cristianlopezchavez7100 Місяць тому +1

    One video watched and I’m hooked. Im about to start sayings shut up, it’s easy every sentence now 😂

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    @menahilkhalid3286 2 роки тому +1

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    @alninsea19 Рік тому +1

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    @deemakharroub293 2 роки тому +3

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    @umartemiraliev6561 2 роки тому +1

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    @hadeer5843 2 роки тому +1

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    @Empress426 2 роки тому +1

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    @farihahossan4389 Рік тому +1

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    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Рік тому +2

      I am honored! Thank you! I hope you enjoy the entire biochemistry playlist: ua-cam.com/play/PLYcLrRDaR8_dKo6Nu1Dw1efJGkDpuZGEy.html&si=KHUbKUqhwUjbWIhe

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    @Zortilottozort 4 місяці тому +1

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    @masterno8576 10 місяців тому

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    @elsiebadze8219 3 роки тому +2

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    @avantikadas2516 10 місяців тому +1

    "Shutt up it's easy"____ oh you just stole my heart. I don't seem it easy, that's why entire the day was encased with this topic.nxt week my exam.yea u helped meee❤

  • @jagathnambiar7138
    @jagathnambiar7138 2 роки тому +1

    This video is great thank you so much I was a little confused on titration curve when I was reading the book and this video cleared it up I really appreciate you making this video.

  • @SnipeUL8ter
    @SnipeUL8ter Рік тому

    I am taking the MCAT tomorrow....and I just now found your channel....R.I.P......loving it but hopefully I won't need it after tomorrow!

  • @Khushi_Chemistry
    @Khushi_Chemistry 4 місяці тому +1

    Excellent explanation 🎉🎉

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    @phsalma230 3 роки тому +2

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  • @Fifaafifa107
    @Fifaafifa107 4 місяці тому +1

    Great teacher i loved it

  • @aniketgupta5480
    @aniketgupta5480 3 роки тому +4

    Thank you medicosis😌❤

  • @parthsharma6079
    @parthsharma6079 8 місяців тому +1

    fantastic video till now i just know the definition of pI but today I understand why it so

  • @لصاحبالزمان-ج5س
    @لصاحبالزمان-ج5س 3 місяці тому

    رائع، ربي يوفقك🙏

  • @qamaralsadi6678
    @qamaralsadi6678 2 роки тому +2

    Thank you so much ❤️
    I really enjoyed... you are make it, easy and funny 😂

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    @sarak. Рік тому +1

    You literally cured my MCAT anxiety 😮

  • @SupposedToBeStudying-y6l
    @SupposedToBeStudying-y6l 5 місяців тому +1

    Thank you, Medicosis! Also, I have to say that you sound so cool, my guy!

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    @Alexandra-sj1qe 3 роки тому +3

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    @yasmenyasmen4198 Місяць тому

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    @mohamad5722 Рік тому +1

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    @maryhara2053 4 місяці тому +1

    The best ❤🎉

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    @mariajamshaid9922 2 роки тому +1

    Thanks for such an amazing explanation

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    @cja12345 3 місяці тому +1

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    @lohorsanyal617 2 роки тому +1

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    @Tabarekoday 2 роки тому +6

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    @leatileramasongwane2464 Рік тому +1

    I like the freaky part of this Video😂😂🤣.Thank you so much. we will keep coming back

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    @laraibisrar07 2 роки тому +1

    Thanks alot from Pakistan Sir 🇵🇰

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    @elizaclouds 7 місяців тому +1

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    @matthewramirez3450 Рік тому +1

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    @jayashiTGUY Рік тому

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  • @medicalbiochemistry_
    @medicalbiochemistry_ 3 роки тому +2

    Always creative

  • @annabellanatalini2113
    @annabellanatalini2113 Рік тому

    How would you calculate the percentage of availability certain structure? For example, the percentage of structure B in a pH of 3?

  • @rupamkhatua7093
    @rupamkhatua7093 2 роки тому +1

    Nice video, really helpful

  • @farhanshaikh1690
    @farhanshaikh1690 3 роки тому +1

    Excellent😊

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    @teezeeclasses1394 3 роки тому +2

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    @MwambaMemory-iy1ms Рік тому +3

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    @melanieclark6490 2 роки тому +1

    Great video, thank you so much

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    @hibaabusalim6044 3 роки тому +1

    keep going 👍

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    @muhammadjaved620 Рік тому +1

    😂😂😂.........oooo.....u r great 🙂🤗love the way u teach..........💓

  • @Apk3rbBlogspot
    @Apk3rbBlogspot 2 роки тому +4

    Why does fully protonated amino is + charged, while the fully protonated carboxyl is not

    • @Vodnuth
      @Vodnuth 2 роки тому +3

      Good question, because oxygen atoms prefer 2 bonds the deprotonated form of COOH has a negative charge associated indicating that one of the oxygens has electrons it wants to share. Whereas when the C-N2 is protonated the N atom has 4 bonds and nitrogen prefers to form 3 bonds, so the postive charge indicates that it is sharing more electrons than it usually likes to. Hope this helps.

  • @noname-iv4hq
    @noname-iv4hq Рік тому +1

    i love u dude this is so fun and funny hahaha

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Рік тому

      Thank you so much! I appreciate you!
      Would you please help me by sharing my videos with others?

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    @MoratelIpelengMadibeng Рік тому +1

    YOU are a amazing

  • @rashaal_sarhan981
    @rashaal_sarhan981 3 роки тому +1

    Thank you so much

  • @kerrigangafford8498
    @kerrigangafford8498 19 днів тому

    why are we using the two carboxyls for PI for Glutamic Acid instead of both "wings," I know you said two is more than one but i fundamentally do not understand why

  • @dennisnaminse9047
    @dennisnaminse9047 2 роки тому +1

    I love this❤‍🔥

  • @venusz6134
    @venusz6134 2 роки тому +1

    Man.. and you are hilarious LMAO. I'm switching from Khan Academy to your channel

  • @ju-iki
    @ju-iki Рік тому +2

    صيدلة بابل مرحلة ثالثة شلونكم 😂❤

  • @Crackitwinit
    @Crackitwinit 2 місяці тому

    so we have memorize the pka values for all amino aicds right??

  • @kayleemercado4449
    @kayleemercado4449 9 місяців тому

    at what point in the figure is there no titrant being added at the pH points

  • @rosyf123
    @rosyf123 Рік тому

    I lived in Germany 5 years, only ever learned enough German to order in restaurants 😂 now I know zwitterion too!

  • @TomSun-ox9uq
    @TomSun-ox9uq Рік тому

    May I ask why when the pH equal to pKa, the titration curve becomes horizontal?

  • @drp9507
    @drp9507 2 роки тому

    Can you made a playlist for bio Olympiad because I prepare for ibo

  • @lovelovelove-f8k
    @lovelovelove-f8k 10 місяців тому +1

    you saved my life

  • @mammawhat5026
    @mammawhat5026 24 дні тому

    It was love at first “shut up” ❤️

  • @FitHappyAndBlessed
    @FitHappyAndBlessed 4 місяці тому

    I do not see why you included this one as #40 in the General Chemistry playlist. It assumes that the prior three Titration videos have been seen for it to make sense. All the while Acids and bases have not been covered as yet. Acids and Bases are covered in #55, so the cart has gone before the horse. Given all that - it is still an awesome presentation.

  • @nidafazal133
    @nidafazal133 2 роки тому +1

    Why is there greater change in ph at pI?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 роки тому +2

      Nonlinearity of the system (it follows a logarithmic graph rather than a linear one). Thanks for your email:)

  • @giftnwagu5185
    @giftnwagu5185 3 роки тому +1

    Thank you for the awesome video. I finally understand!

  • @alexkyabarongo5411
    @alexkyabarongo5411 Рік тому

    Saved my life bruh, eeeeew

  • @vebzp9573
    @vebzp9573 4 місяці тому

    Link of previous videos of amino acids please

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 місяці тому

      You will find all of them here: ua-cam.com/play/PLYcLrRDaR8_dKo6Nu1Dw1efJGkDpuZGEy.html&si=feR1nKCVZ7R5okVa

  • @melikeguler_36
    @melikeguler_36 2 роки тому

    Amazing