Types of Mutations (Point Mutations and Frameshift Mutations) || Mutations In Genetics

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  • Опубліковано 20 тра 2020
  • Mutations and Types of mutations - This is the video on mutations, causes of mutations, types of mutations (Point mutation and Frameshift mutation) with NEET PG MCQs.
    Definition of mutations - 00:21 minutes
    Mutagens and Mutagenesis - 00:54 minutes
    Causes of mutations - 01:27 minutes
    Types of mutation - 02:27 minutes
    Base substitution or Point Mutation - 03:29 minutes
    Transition mutation and Transversion mutation - 04:13 minutes
    Silent Mutation - 05:01 minutes
    Missense mutation - 05:34 minutes
    Acceptable Missense mutation - 06:17 minutes
    Partially Acceptable Missense mutation - 06:54 minutes
    Unacceptable Missense mutation - 07:55 minutes
    Nonsense mutations - 08:47 minutes
    Frameshift Mutation - 10:17 minutes
    Point Mutation and Frameshift Mutation - 11:27 minutes
    NEET PG Biochemistry MCQs - 13:05 minutes
    #mutations #Genetics #molecularbiology #NEET PG #biochemistry
    Mutation results when changes occur in the nucleotide sequence of a DNA.
    The term mutation refers to the permanent changes in the DNA sequence.
    Mutations in germ cells are transmitted to the next progeny and may give rise to inherited diseases.
    Mutations in somatic cells are not transmitted to the progeny but are important in the causation of cancers and some congenital malfunctions.
    Mutagens and Mutagenesis
    Any agent which will increase DNA damage or cell proliferation can cause increased rate of mutations also. Such substances are called mutagens.
    X-ray, gamma-ray, UV ray, acridine orange, etc. are well known mutagens.
    The rate of mutation is proportional to the dose of irradiation.
    Causes of Mutations
    Errors in replication, If a mismatch base pair is not corrected during proofreading and post replication repair system.
    Error due to recombination events.
    Spontaneous change in DNA, e.g. deamination of cytosine to uracil or spontaneous depurination.
    Environmental factors like chemical mutagens and irradiations, e.g. UV light or ionizing radiation can alter the structure of DNA.

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