This is your brain on caffeine
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- Опубліковано 25 сер 2024
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The psychopharmacology of caffeine and its effects on brain and behavior. Please, like, share, and subscribe!
references
© 2016 Allen Institute for Brain Science. Allen Human Brain Atlas. Available from: human.brain-map.org
Fredholm, B. B., Bättig, K., Holmén, J., Nehlig, A., & Zvartau, E. E. (1999). Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacological reviews, 51(1), 83-133.
Fredholm, B. B., Chen, J. F., Cunha, R. A., Svenningsson, P., & Vaugeois, J. M. (2005). Adenosine and brain function. International review of neurobiology, 63, 191-270.
Juliano, L. M., & Griffiths, R. R. (2004). A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features. Psychopharmacology, 176(1), 1-29.
Benowitz, N. L. (1990). Clinical pharmacology of caffeine. Annual review of medicine, 41(1), 277-288.
Strain, E. C., Mumford, G. K., Silverman, K., & Griffiths, R. R. (1994). Caffeine dependence syndrome: evidence from case histories and experimental evaluations. Jama, 272(13), 1043-1048.
Ferre S, von Euler G, Johansson B, Fredholm BB, Fuxe K (August 1991). "Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes". Proc. Natl. Acad. Sci. U.S.A. 88 (16): 7238-41.
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Image references
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By OpenStax College - Anatomy & Physiology, Connexions Web site. cnx.org/content..., Jun 19, 2013., CC BY 3.0, commons.wikime...
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By Frontiers in Physiology - journal.frontie..., CC BY 3.0, commons.wikime...
Please continue doing whatever you're doing. Resources like these are extremely valuable, especially to students. I hope you're learning a lot and I hope the knowledge serves you well too.
“Less GABA” means more glutamate. More glutamate means an increase in anxiety. Got anxiety? GIVE UP coffee. There’s a start.
It worked for getting rid of my anxiety, almost completely.
I take wellbutron to barley make it wonder how quitting coffee compares
So I've been trying to cut down and/or eliminate caffeine as I find I was getting really dehydrated due to the constant urination and I was also up at night till about 1am - sometimes 2/3am. I've switched to decaf tea and BOY what a difference. I'm hardly ever running to the toilet. I'm in bed by 22:30 sometimes and I'm waking up feeling refreshed. Now I know some people say decaf tea has chemicals in it, but for now I'm more than happy with the results.
The withdrawals were.....unpleasant to say the least. Headaches, general tiredness, lack of drive, no sex drive whatsoever and for the first 3 days I actually couldn't sleep very well. These passed within 7 days though. *Worth it* doesn't come close. I still have a cup of regular tea now and then as well as some chocolate, but I'm never touching coffee again. Even the smell has changed from pleasant to revolting.
Next of the list is alcohol and nicotine. I changed from smoking to vaping and have cut down on drinking a lot, but I'm going to push to cut them down even more this year.
It's good to take breaks...watermelon rind for the sex drive 😋
Came across this comment half a decade later... How are things?
@@stefaniadiamondcutYOU'RE good for the sex drive😉
The smallest amount of caffeine make me short circuit. I get palpitations, and tingling in head, hands and feet. And my body feel very heavy.
My bp get elevated also. The worst feelings ever.
I used to to love coffee. And drank it daily.
I don’t know why you don’t have more subscribers. This was sick. It answered so majy questions. Keeep it up
I find it very comforting to listen to a guy in a comforting hoodie
WOW !
Very unexpected from a man wearing a hoodie.
What a stereotypical and close minded comment
This is so well referenced, such a rarity with youtube videos! Fantastic delivery also, thankyou x1000 :)
This channel is gold. Subscribed!
Very nice simplified presentation thank u
Your channel is truly good. You seem to do lots of research, and find great ways to present coherent and organised information. I hope you keep on making this videos, they are of great help for me and I'm grateful for them.
dude love the way you teach that stuff (though on 0.75x is easier to get the idea). nice work and thank you very much
Great explanation
Caffeine ruined my life
Same
Why
@@biesman5 it made me anxious and nervous
Brilliant 😊
great vid
altair has returned!
Furthermore, saying that GABA reduces activity is an extremely generalized statement and in practicality often not true if its just a small increase.
Yes it is primarily inhibitory, but in this way it seems to inhibit cognitive reflection as well, making people to not overthink their actions as much, right? Thinking of alcohol as a GABA releaser and it's effect in inhibiting reflection and worrying.
wanted to like this but little effort is made to help the viewer understand if the impact of caffeine is good or bad.
Agreed that's all that matters in the end
12:22 "One thing that high ACh will do, is it will increase the activity of the VL preoptic nucleus"
12:48 "...as well as increasing ACh, which also shuts off the VL preoptic area"
This gotta be a mistake. I'm really confused of what to believe now.
yes that was a mistake! thank you for letting me know. Adenosine activates the VLPO while acetylcholine shuts it off. I added an annotation
Wait, so what am I suppose to go out and buy? ...such confuse
Anyone here suffer with OCD and think that caffeine may be the culprit??
Yeah really do think it makes things worse
great id!
I have a question you may or may not be able to answer--does caffeine effect everyone's body in a similar way? I ask because no matter how much or how little caffeine I have, it seems to have absolutely no effect on me.
Edward Joel some people metabolize caffeine differently than others. Due to genetics.
Add sugar
Bro, make more videos! Quality content at it's finest
Caffeine do harm old people more than young. Some old folks lost good sleep cycle with irregular heart beats like me.
Im so sad its not paying off and actually harmz my psyche caffine
Basicly poison😢😢
Grog confused.
Which field of study is this from? Neuroscience? Pharmacy/medicine?
I study neuroscience, but this specifically would be called psychopharmacology, or neuropsychopharmacology = the study of dugs and behavior
dude what?
P
this shit is woke af
I need my drugs!!
🍌🍌🍌🍌🍌🍌🍌🍌
Lol me who a gym rat taking pre workout makes coffee garbage pre workout be like cocaine.
Why are you dressed like a cheap Jedi?