When I had a clinical depression I used to run around 50 miles a week. Every time I told myself “it must help my depression” but after every run I felt more and more exhausted both physically and mentally. Going for a run added more stress and anxiety because I expected it to heal me but it didn’t. Then I started blaming myself for not training hard enough which worsened the symptoms of my depression even more. Eventually I started meds which helped me to get back on track. Exercise, diet, and meditation might help but when you’re so deep into depression it might be useless
i come to this conclusion due to going through the same experience as you. i think what happens is you associate the pain from running to the internal pain your experiencing, for me it was a relationship breakdown . what happens to me was over time when I trained i felt the pain of depression from the breakdown of my relationship when I wasn’t feeling too depressed. This made me realise how powerful and heavy depression is. it clinged to the things that actually made me feel good and become the association.
@@IdontspeakBro. I’ve never thought about it this way, but it makes perfect sense actually. After my depressed runs I quit running for quite a while because I probably must have linked it to all these painful emotions. Thank you for your thought. That made me look even deeper in what was going on back then
My son had Schizophrenia..He took his life in 2019..I currently am suffering from chronic depression and severe sleep disorders..i am alll over the place...😢Thank you for having this channel and helping people like me..there is no end in learning...❤
I am so sorry you experienced that :( I will hold you in my heart and pray that you may experience some peace soon. Maybe find a support group for those who have a similar experience to subside some of the loneliness.
I am so very sorry 😢. I lost my son and went through that too. It has taken a long time for me to come out on the other side but it did happen gradually. Keep loving yourself through and practice self care. So very sorry, truly a nightmare. ❤️
my dad had schizophrenia too . He passed away from a heart attack at 60 . I’m sorry for your loss and immense pain ❤. I do yoga nidra and celeapram helps heaps for my anxiety .. i loved my dad but schizophrenia took over . bless you ❤
Sorry for your loss, something that helped me cure my depression and negative thoughts is a supplement called 5htp , it increases serotonin in your brain and helps see the brighter side of things. Please look into it, it really helps with depression and sleep as it increases melatonin. I take 150mg per day. Do not take it with other antidepressants SSRI's which can cause too much serotonin in the brain called serotonin syndrome. 5htp doesn't have any of the side effects antidepressants do. Hope it helps, sending you prayers 🕊
Dr. Huberman your contribution to humanity is substantial. Humans being able to work at maximum potential is a beautiful thing and your work is making that possible. Thank you sir !
This podcast is one big reason I have come out of depression and feel so much better. I get my sunlight, eat my omega 3s, vitamin d, ashwaganda, and L-theanine and I’m speechless at how big of a difference it’s made. I’ve stopped crying and falling into despair, and upsetting things aren’t a tsunami of sadness anymore. I cannot thank you enough. May God bless you and your efforts. (The other factor that helped is PickUpLimes video about feeling lost, and using the printable worksheets she gives to find out what my values are and living according to those)
@ I am not but I appreciate you asking. You are right; it is horrible. I am beyond exhausted from fighting. I ask that God lighten your burden if you are dealing with it. May you find peace, love and joy again. Take care.
this video didn't touch on what depression actually is, or how to get rid of it. it attempted to use hard science to explain and solve a basic metaphysical problem. its not that complex, philosophers who didn't have access to electricity broke it down better 1000 years ago. depression is a state of hopelessness. example "grandma who I loved so much is dead and she's never coming back", "it's too late to get a higher education and better my life I need to work a terrible job forever now", "im unhappy in marriage but need to stay for my kids". these are the types of internal dialogues that cause depression, SPECIFICALLY because your subconscious feels hopeless. it may not in reality be hopeless but that's your perception. spend 5 hours alone in a room with nothing but a pen, paper and your thoughts - it will be scary but you'll gain clarity. either that or go see a shrink who can help you explore what you feel hopeless and chronically anxious about. this guy is a goof.
I love that Huberman truly does stick to the science. Nothing really philosophical, moral, nor opinion based. Purely fact driven. It’s such a breath of fresh air.
science? more like bad science! almost the whole video is antiscientific. The seretonin/depression myth has been busted just last year by Dr, Joanna Moncrieff. do your research. psychiatry is back to 1950 again
As someone who suffers with extreme severe anxiety I can totally relate to her. I would stop eating for days at a time as a punishment. I worry a lot about my life, everyone around me and pleasing everyone. It's absolutely crippling, so glad she got the help she needed, lovely young lady it's so sad that society has 1 in 3 people suffering mental health issues. I hope everyone seeks help
Can you help with the reliable source I would really appreciate it. Many people talk about how mushrooms and psychedelics treats anxiety, but nobody talks about where to get them. Very hard to get a reliable source here in Australia. Really need!
Yes, doctor Greg mushroom I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.
I'm almost 40. I would guess I had my first depressive event around 10. Since then I've spent 20 +years casually learning about depression, and never has information come to me in a more digestible, empowering way. I have enjoyed your podcast for many months, but this one feels like it was for me. Thank you!
@@sourgummyworms8069 knowledge is your friend, use it and it will get easier. The fact that you're watching this video gives a good indication of that.
@@sourgummyworms8069 I think it depends on circumstance but if you learn to love yourself and others despite their actions, it will get better ,and, forgiveness of others will inadvertently heal you in the process.
I’ve had severe depression, getting out of bed feels like jumping into an ice lake, eating breakfast feels like eating feces. And the intensity of these feelings can vary all over the place, you cannot plan anything because your perception of reality can change just like that. What in one second felt like a nice walk in the country, feels like a stroll down a never ending corridor
I suffered from depression all my life. At about 55 years old I took a food allergy test which showed I had a gluten/wheat allergy. I removed wheat from my diet and after about 2 weeks I was depression free. If I accomplish nothing else in my life, I am depression free.
Schizophrenia: I hallucinate important things all the time. Bipolar: WHAT DO YOU MEAN ITS NOT IMPORTANT!?!?... never mind... i dont care. Narcisistic personality disorder: In truth, I am the only really important thing in existance.
I’ve become hooked on your videos this year and while others (doctors) in other professional fields have more credentials on some of these things. Your insight in these podcasts has been satisfying a lot of my curiosity over the years from my depression to adhd to my anxieties on nutrition and caffeine. So many bouncy thoughts roll through my brain from a speed from 1-100, one of my Monday highlights (an off day) and also satisfies me when I’m feeling restless when it’s slow at work. Would love to hear caffeines effects on depression/adhd, or if there already is one. You’re arguably the smartest person I’ve heard talk about anything!
I live in Norway, and it's been common practice for 50 years, for society to promote consumption of Omega-3/EPA's, especially to help with seasonal depression due to the darkness/climate. In addition the promotion of good work/life balance, which generally leads to less long term stress - this is a powerful combination.
You are a true ACE* for humanity!!! Your *ALTRUISTIC/COMPASSIONATE/EMPATHETIC* nature and contributions to make neuroscience more accessible, in order to improve lives, is a true gift to humanity and the future. Thank you
Literally life saving episode. I'm just tuned in because I'm really struck by depression right now. And for someone who is described as a person with lot of positive energy, mental strength and kindness facing with this is really impossible to realise...
Thank you soo much for this. My daughter has been suffering from severe depression and your discussion is a god send. People, family especially tend to find it difficult to believe the physical aspect of depression on a person. They call her lazy and mentally weak for not knowing how to deal with stress. They say just suck it up what you're feeling isn't real you just want to deal with difficult aspects of life. I can now share this video where you thoughtfully and thoroughly dissect depression in a way that is understood and for me personally you give me hope. My daughter has tried to take her life 5 time now and is just turning 21. Thank for this gift and please continue to shed a positive light on mental illness and bringing hope to those who struggle from it or are directly affected by it like myself who as a parent wants their child to thrive and find happiness. Than you again!
Thank you! We're blessed She hasn't had an attempt in about 2 years now. She's far from being better, still a lot of bad days but with more strategies we learn of, the more tools we have to turn the darkness off or at least silence it and have the will power to continue being consistent. She's working in the mental health field now and is in her 3rd Year of college. Always be Blessed to have the ones we love by your side every day you have a chance.
Explain to them that telling someone to “suck it up” or that “they’re mentally weak” is like telling someone with cancer to just suck it up. Depression isn’t a choice it’s a mental illness
I've suffered depression probably my entire life. Especially since I got my diploma. The fear of failure, the expectations, the feeling of being lost has caused me depression for years. I sleep too many hours and I wouldn't need all those hours to be honest, but I feel exhausted. When I trip I notice different habits and improve my sleep schedule. Thanks for being a positive energy in my life Andrew
People who suffer from mental illness are often called out for not wanting to get better. I'ts incredible to see how many people watch dr. Huberman' videos and thank him for saving their life. Looks like people WANT to get better, just didn't know they could. I REALLY need to get better from depression to take care of my husband and my two kids. I'm irreplaceable for them. We actually want to grow our family. I also have so many projects to accomplish. But how could I if depression kind of forbids me to simply brush my teeths or take a bath? All the knowledgment that dr. Huberman shares for free is helping me improve my treatment significantly. So THANK YOU, dr. Huberman! You're a life savior. God bless you!
I've been on anti depressants for almost forty years. Tried to get off them many times and eventually gave up. I was severely depressed by the time I was 14 years old. No one ever tried to help me manage the disease with nutrition, exercise, and supplements. I'm glad the science has advanced.
I still take 30 mg duloxetine. Arthritis keeps me from getting off the last 30mg- I am in pain all the time. I don’t take anything for it. Long term use of ibuprofen almost killed my mom (stomach bleed), so I know it’s not good for chronic pain. Waiting for Medicare to start so I can at least figure out how bad my bones are. They wanted to fuse some discs thirty years ago and I said no. I made it this long, but it’s gotten a lot worse.
@Bioman Smith I was able to cut the dose in half, but the depression came sneaking back. And then, it roared. I'm in the process of increasing the dose, and starting to feel better again. It is what it is. I don't drink alcohol anymore (quit a few months ago), but I've become a bit of a pot head. 😏At least I'm on the down hill slide (senior citizen).
I was diagnosed with neuropathy pain caused by depression. I went through four months of antidepressant treatment that helped me sleep, but that's all I did. At the beginning of the year, I set out to get on my feet and started looking for answers, and that's how I came across this podcast. In the last two months I have applied many tools learned here. It's not a day when I don't have muscle aches, but every day when the pain is below 5, on a scale of 1 to 10, is a good day. Thank you Dr. Huberman
@@andreabakacs9804 You're looking for hard scientific answers to basic metaphysical questions. Great philosophers of the past are 10x more intelligent than the average modern scientist. They have more practically knowledge about depression, can accurately describe exactly what it is and how to solve it. To do that you'll need to climb up through hell, so it's not a surprise most people just want a pill. If you actually want functional solutions go look up depression from a philosophical perspective..
@Andrea Bakacs please try the medicinal mushrooms either lions mane or Turkey Tail. Changed my life!! Fibromyalgia, chronic fatigue, adhd depression and anxiety. X
Thank you for pushing to make information like this accessible to everyone, it really means a great deal to alot of people, especially content with this amount of depth and cover. This very video finally gave me the final nudge to make my appointment with my GP to get my symptoms checked on. I've had depressive symptoms on my shoulders for almost 2 years now and I hope this can help. Again, thank you for what you do, and without videos like these I don't think I would be able to make the steps I need to take on my own. You've probably moved thousands to do something similar, whether it is taking that step, or making them aware of what they might have on their shoulders too.
@Josie Adams thank you! I was able to get some help, I'm on week 2 with my Prozac prescription, and I'm starting therapy in 2 months. The first step was definitely difficult, but I really do think it'll be worth it in the future
Your mindfulness while speaking and selection of appropriate words with the phrases of clarifying those words on the sides it's just unreal.. It shows how thoughtful you are while creating this podcast. Greatly appreciate your work❤
OMG I wish everyone would watch this. I am judged daily by people who believe I just don’t want to get better because I don’t work out and cannot keep a regular sleep schedule (including doctors!). For one second I just want someone to see how it feels to be judged for not working out when you can’t brush your teeth. Or to go for a run when your leg is broken. What people do not understand they use to blame those stricken. It’s terrible.
I find it interesting to hear emotion tied in with depression because when I had MDD I didn’t have emotion, I didn’t cry I didn’t feel sad I felt complete nothingness, a shell of a human. Oh also the exercising thing from earlier on, that depressed people lack motivation to go for a run, it feels physically impossible, we don’t lack motivation we just feel like we are slowly dying and standing up is at times too much. That’s why so many people with depression sit in the shower
@@carynmartin6053 If you work you likely have to do it but for me yes it is soooo hard however once I do it when I have any urge it makes a world of difference for me & just leaving the home in my car. A drive. I think it is vital however for you to make that decision when your ready. It doesn't help when another tells you. If you have that shut it out. It is like telling an addict to stop. Sure they may even decide to stop temporarily but they relapse for many reasons but being forced into something is just going thru the motions usually for another. You take full control over your depression, your mind & body. That means your time. Try 1 just one small thing & a shower is a great place to start. If you don't feel well after then rest then start again. Really small steps. One step at a time. 🙏
I want to express my gratitude for this, Prof. Huberman. Since the day you announced that you were going to start a podcast, I have been waiting patiently for an episode on depression and here it finally is. One always has an eagerness to know of one's own afflictions if there is a will to get better. Thank you so much.
@@hubermanlabthank you sir! You’ve inspired me to learn as much as I can, to fix myself or learn how to best care for myself, and have motivated me to go back to school, surround myself with academia and to, hopefully, give back to those around me. Seriously a fantastic role model
im struggling right now and andrew has helped me more than the hotline has. he gives actual steps, the light at the end of the tunnel. i hope to thank him one day
That two-dollar philosophy lesson could just be translated as the algorithm working as intended, assuming you've searched up depression- and neurology-related content before, and maybe other health stuff and channels that the people who watch Huberman have watched.
I cannot pay attention to his lessons for the whole hour and half he speaks. Its because of my chronic depression and chronic resulting laziness. I still appreciate what he is doing with his time. Social media is a poison. But things like this. Some youtubers. They make me feel like internet really has made life for some people better. Especially underprivileged people with no formal education or the availability of these discussions in their lives. Huberman has connected millions of people all over the world into a community of self improvement. Real science based self improvement. Making our lives better has never been easier. I am grateful to exist in this time and in this place right now. Thank you Dr Huberman. I hope one day you realise the utter magnitude of people you are helping all over the world.
Been there, diagnosed with clinical depression few years ago. For me it was running and reading that saved me. Thank you for the material and some insights that I had in this podcast. Keep it up
Would you consider yourself « cured » or « free » from depression ? I just need some hope with some positive testimonies of people who overcame that. Thanks
@@Zezeguizee I have suffered depression. My best advices to you: 1) Do exercise. Lift weights. 2) Don't take things personally. 3) Improve your relationships. 4) Practice Gratitude for what you already have.
I'm bipolar, and this year Andrew saved me with his podcasts... it gave me hope to try to help myself. Pls join us in the FB grp "Notetakers of Huberman Lab's Podcasts."
@@Zezeguizee Yes, i consider myself not only free but so much more powerfull than in that period because now I know hot to detach myself in a period that is going to happen something similar.
I listened to this episode and I sobbed. I've been through years of depression, it's hell. But there's always science and it has helped me all these years. Thank you Andrew , for so many of us your voice inhibits the re-uptake of serotonin better than any pills.
@nackedgrils9302 Thanks so much for letting me know. I hadn't been able to listen lately. My deepest condolences to Dr. Huberman. I know the loss--all too well. Rest in peace, Costello🙏🏽
That's what sent me down my latest spiral was losing my best Kitty friend of 23 years a year-and-a-half ago. The last few years of her life I was just living for her to take care of her and make sure she was comfortable and well taken care of. Now I feel completely spun out and literally all alone. I got other things going on that are pressing on me but that was the major catalyst. I keep thinking I'll surface again but these are dark dark days. It doesn't help that it feels like the world is crumbling all around us as well.
I had an experience that surprised me. I am 74 and wanted my testosterone checked. The free testosterone was low. I started taking androgen gel. What surprised me was the impact on my mood. I did not think there was a problem, and am already taking Zoloft. But after staring androgel, my mood was significantly impacted. Particularly in the sense of much less easily irritated. And generally enjoying life a bit more. Probably less anxiety
The greatest thing about all that you've said throughout this sessiom is - you've made it clear thst those who are actually depressed or close to being so, are most likely not at fault for it. The opposite of what they feel like. You give them hope that they can get better amd that it often doesn't even require medication to achieve that goal. Thank you for this extensive, very informative and uplifiting session, I really appreciate it, as do many many others without a doubt.
Dr. Huberman we are speechless about your knowledge , I am MD but when to your speech I can see clear pictures that I couldn't see before and was my questions , your are the greatest of all and I can say we all love you for your work.🙏
I listened to this and found I was doing most things already.(not the drugs) My biggest trigger is low energy. I went out and bought some creatine and the effect is just amazing! I have been taking 2.5g at breakfast and 2.5g mid afternoon. I am the same happy energiser bunny I was in my youth. I am 65yrs. No procrastination or scrolling. Yay! Thankyou so much!
@@trudibarraclough478It helps to be mindful when supplementing with B6 because even though it's water soluble it does get stored in the body. My daily multivitamin and protein shake contained B6. After 6 months of taking both I was diagnosed with B6 toxicity. It seems many "popular" protein shakes, energy drinks and hair/skin/nail supplements add vitamin B6. :)
A lot of depression comes from being abused or neglected, especially as a child. If you weren't given attention, love and stability by 2 parents then you're screwed. I feel like a broken human to the point I sabotage possible relationships and love because I'm afraid it's going to hurt me or them and also I'm afraid of being loved because I don't really know what and how is it like while somewhat longing for it? It's weird to be human in such circumstances and exhausting I numb myself out with video games and internet, occasionally weed.
I’m not discounting anyone’s traumas, childhood or otherwise. We all have them. This is human, welcome to life. My tenets have been: Lose the blame, it’s pointless and leads to victim hood and resentment, anger, etc. Realize that when you judge something or someone, it will mirror your action at some point, and use that for self reflection to bring awareness to your own choices and actions. Forgiveness. I can’t stress this enough. Of self and others. Become an observer of humanity. When you understand others, you will come to know yourself on such a deep level that you become the rock. The tree. The ocean. You will be able to feel so deeply, and cry at what’s painful and beautiful and you will come to learn it is all the same. You will be able to laugh at yourself, and with yourself, which in turn lightens your load and everyone else’s. Love deeply and wear your heart on your sleeve without fear of abandonment and rejection. You plant seeds and your energy goes out. Be kind. Everyone is doing their best, whether you think so or not. 🌿🤍✨
I'm so sorry you have been thru so much but don't despair there is healing. It's very good that you are aware of things. I pray you find the best tools to forward your healing journey.
I almost fell out of my chair when you mentioned tryptophan converting to a neurotoxin where there is extreme inflammation because every time I take it, instead of becoming happier, I'm more depressed and anxious. This is fascinating stuff. Thank you for shining a light on something that has been baffling me.
Thank you for sharing this, I was almost about to start supplimenting with tryptophan. Now that I know what the pathway is I am not about to do that because I can tell there is quite a bit of inflammation in my body right now.
@@Ronaldinho1996 it did for me. 5-htp coverts directly so it is the precursor to serotonin. Tryptophan would have to first be converted to 5-htp then to serotonin. This is why for me personally both of those agents ended up causing more issues than support. :(
I have witnessed many family members whom suffered with major depression until their suicides. If they had known the science, things may have been very different. Education is key to modifying patterns in our lives and your podcast is initiating real change in the world. Thank you Dr. Huberman : )
lol thats so stupid to think some scientific protocols that slightly alter your diet and habits are going to solve suicidal thoughts. it's a much bigger picture than just biology and isn't so easy to fix.
After a major stressor 4 days ago and being in what you called a vegetative state ever since, I started watching this. I just took 1600 mg of EPA/DHA 1:1 and 5g of Creatine and I feel like I can maybe go take a walk. Thank you! ❤
@@StunningTransformationshis person isn't experiencing long term depression, so if it's working immediately and they are no long depressed, it has worked. There would be no damage. In any case, the brain can always heal given the right conditions.
Great episode. My comment regarding crying: quite often people living in depression do not cry at all. Even during the hardest experiences. They are like frozen. Do not process emotions spontaneously. Only by revealing the past traumas, and crying them out they can heal and start enjoying life in its all aspects.
very good advice. I noticed too that I cry very seldom but now I try to do it regularly because It really helps and it's freeing. It sounds maybe weird to say "cry more often" but it actually is beneficial
After realizing that I am a pile of tubes with various chemicals inside, with two pieces of brain pushed out so my brain doesn't have to sit in total darkness. Knowing that what I feel as happiness, it's just a flood of serotonin in my system or sadness - a dopamine drop. That knowledge is liberating in a weird way.
Applause! Incredible job Dr.Andrew Humberman. I myself suffer from clinic depression for the last two and half years , tried therapy and medication but found no major relief . I gained a lot of insights about depression backed my scientific evidence. I hope it will change many people lives for better. Keep it up man
P. T. S. D. From childhood often causing chronic depression in adulthood. It's often neglected in families because of denial and shame. Mental illness is now so common that it's acceptance is very common but under treated. Get help with issues like these and have a satisfying life.
Just watching and listening content like this episode alleviates my symptoms. Everything about the pleasure-seeking, pleasure/pain imbalance, and anhedonia were especially enlightening. My emotions, actions and everything makes sense now, and I don't have to blame myself for just being miserable. You also describe many things I've found useful in battling my demons. Dr. Huberman, you have an excellent understanding of how depression works and are great communicating it clearly, and precisely. What a great man, you deserve much more recognition for your hard work. Thank you so much for sharing the information and your wisdom, everyone should watch this.
Psychiatrist here - thank you so much for posting such amazing content. This podcast alone has taught me so much. Thank you. Wondering if you could do a similar one discussing anxiety. Would complement this episode nicely. Also discussing relationship between anxiety and depression. My apologies if you have one out on anxiety already and I've missed it!
Tool "Unwinding anxiety" of the psychiatrist and scientist Dr Jud Brewer. Anxiety as a thought habit loop. A lot of podcast on you tube from him. On changing habitual behaviors. Thinking one way or another can also be viewed as a behavior. I have subscribed to his App and it works. Better than medication.
As a person that doesn't go to a doctor: - breathing exercises (wim hof) - thinking of loved ones - listening to Eckhart Tolle These are things that actually help me in the moment and bring me through the day I probably should do them daily, but I don't.
The most organized and comprehensive episode and podcast ever! My dopamine level is through the roof because of the topics of this month. I have been waiting so long for this... Thank you
Very useful episode for everyone, professionals and patients. However, I think a topic addressing the effects of cognitive behavioral therapy would also be really cool!
just listening to your lecture has made feel better. I feel the anchor of depression what weights me down get lighter. I think it's because you explain the complex emotions and thoughts going through us in a simple way and makes you feel normal.
I am bipolar and one of the best time for me was on the ketogenic / carnivore diet that high fat was so good and help me much better than any pills .. I lost so much weight I had to modify my diet , now I am going back on my high fat !!
Thank you so much, this is exactly the kind of episode I was hoping to see from you. Personally, the biggest improvements I've seen during my history of depression have always come from hearing and understanding the actual science surrounding my circumstances. Not only does it feel affirming to know the neurochemical roots of my own experience - it also gives me reassurance that improvement is possible. Again, thank you for putting this stuff out there for free. It's hard to come by stuff like it, especially as someone who has - and is still spending my teen years met by mental health professionals who often either don't want to or are unable to offer this scientific point of view.
I wonder how sub-consciously self-sentient the brain is when we learn about these things... Does it help the brain know its self as a functional organ, & influence changes in development to improve function, etc? Lol.
@@Flusterette There's no indication of this being the case. Brain is not a separate organisms which starts gaining it's own conscious (outside of the conscious which we already have), learning about how it functions and thus changing how it functions. Who knows, maybe, but there's no evidence supporting the theory that brain is a sentient being within a sentient being. What happens here, if you pay attention to what OP said, is that it's not the actual knowledge presented by dr Huberman that made OP (and other people in comments) feel better, but a *belief* that this is true. OP didn't try out protocols for few weeks and started to feel change. They heard that "science says there's a way to fix it and it's curable for everyone" and they believed it on the face value (whether it's true or not is completely irrelevant, eg. dr Huberman could have said that sunning your balls 30min every day has been shown to cure depression in 99.9% of cases and OP would be just as happy). It's exactly the same as a religious person going to their spiritual guru, who touches, them, says few prayers and they feel much better right away. That's why there's this interesting paradox where people who don't really understand how scientific method works and that nothing is definite and absolute in science, do feel better applying some scientifically developed method (often psuedo-scientifically), while people who know about those limitations and no method is perfect and won't work in 100% of cases, need some sort of spiritual guidance to feel better. That's why belief is such a powerful tool, especially when it comes to mental and emotional health.
@@kalash_nikov I'm 100% on the same page with you, just putting out my curious pondering into the void for amusement's sake. But thanks for taking the time.
@@kalash_nikov Thanks for the (indirect) reply. I might not have communicated it quite right, but I’m more so appreciating the combination of protocols and getting served the science of why our current (and extremely limited) knowledge of the brain and body supports that it might work. Again - my experience is that some (empathizing SOME) psychologists tend to hand out extensive protocols and rely largely on a very “fluffy” and metaphorical version of the mind. This is of course extremely useful - if it wasn’t it wouldn’t be used. Just like you said, belief is very powerful. Psychology works even if we don’t always know why - the most important thing is that it DOES work. I really don’t think mental health treatment should be based around serving scientific facts. I’m more than aware how how non-definite science is, and I’m aware that my comment was very anecdotally and emotionally based. I’ve just experiences some professionals talking down to me because of my age. It was frustrating to be told all of these metaphors that I should apply for my mind withtout even just a small hint of “this is actually about changing the neurochemistry of your brain.” I’m not saying this is the case for everyone though and I really don’t hope I come across as a “yay science” type who believes that as soon as my favourite internet-scientist says something, it’s instantly gospel. But thank you for the comment. It was very thought-provoking and all of your points are very good.
Dr. Huberman I am 82yo and have described you as my guru to anyone who will listen. I have discovered that exercise does help with depression but the important discovery for me is obsessive thoughts leading to depression. Have tried to break myself of that destructive habit which fortunately does not happen often. My mother did it often so I guess there is a genetic predisposition involved. Am just coming out of a mild depressive state now. Always consume omega 3 as supplement and eat salmon several times a week. I would love to have the secret to stopping obsessive thoughts when they do occur. Possibly removing myself from the stressful cause is the answer!! Thank you for what you do to help us!
Thank you from the bottom of my heart for explaining so beautifully and simplyfying it for the public from non science field too Dr Huberman you are amazing human being. God bless you !!
I can't wait to finish this! I just can't believe we have access to someone like you, and have the chance to learn so much from your vast knowledge...it's deeply appreciated!!
I too have become addicted to these outstanding and highly interesting/informative podcasts by Dr. Huberman. I was diagnosed with Bipolar II , yet I feel more like its major depression as I can't think of many times I ever feel joy. I thank you Dr. Huberman and I have ordered creatine and fish oil pills from Momentous. God bless you !! And thank you !!
🎯 Key Takeaways for quick navigation: 00:00 🎙️ *Introduction to the Huberman Lab Podcast on mood disorders* - Overview of the month's focus on disorders of the mind, including depression, attention deficit disorders, eating disorders, schizophrenia, and bipolar disorder. - Discussion of psychological and biological underpinnings of mood disorders. 02:00 🧠 *Understanding the pleasure-pain balance in the brain* - Explanation of the pleasure system and its association with mental or psychological anguish. - Description of the release of dopamine during the pursuit of pleasure and its role in motivation. 05:23 🔄 *Breaking the cycle of pleasure and pain for mental well-being* - Discussion on the diminishing returns of dopamine release with repeated pursuit of pleasure. - Importance of entering states of boredom or non-pursuit of pleasure to reset the pleasure-pain balance. 07:45 🩺 *Sponsorship message and promotion of InsideTracker* - Introduction to InsideTracker as a personalized nutrition platform. - Emphasis on the significance of regular blood work for health. 11:33 🤔 *Distinguishing major depression from bipolar depression* - Explanation of major depression as characterized by lows without manic highs. - Mention of bipolar depression and its distinct features, which will be covered in a separate episode. 13:01 ⚠️ *Sensitivity and caution in discussing mood disorders* - Acknowledgment of the sensitivity around self-diagnosis of mood disorders. - Encouragement to be aware of potential symptoms but to seek professional diagnosis. 14:28 🎭 *Clinical criteria and symptoms of major depression* - Discussion of specific criteria for major depression, including grief, sadness, and threshold to cry. - Exploration of anhedonia as a lack of ability to enjoy previously pleasurable activities. 19:19 🧠 *Confabulation in Depression* - People with depression often engage in confabulation, creating elaborate stories that may not align with reality. - Confabulation in major depression can lead to delusional anti-self narratives, portraying oneself as sick or not well. 22:10 😴 *Vegetative Symptoms in Depression* - Vegetative symptoms in major depression are related to disruptions in the autonomic or vegetative nervous system. - Common vegetative symptoms include constant exhaustion and early waking without being able to fall back asleep. 23:37 🛌 *Sleep Architecture Disruption* - Depression disrupts the architecture of sleep, particularly affecting slow wave sleep and REM sleep patterns. - The activity pattern in the brain during sleep phases is also disturbed in individuals with major depression. 26:57 🧪 *Underlying Biology of Depression* - Tricyclic antidepressants and MAO inhibitors were early drugs relieving depression symptoms by impacting norepinephrine levels. - Discovery of pleasure pathways and dopamine's role highlighted disruptions in the dopamine system in depression. 30:22 🤔 *Complications with Antidepressant Medications* - Tricyclic antidepressants and MAO inhibitors relieved symptoms but had undesirable side effects. - SSRIs, while effective for many, present challenges with side effects and varying responses among individuals. 36:39 🧠 *Chemical Systems in the Brain Related to Depression* - Norepinephrine, dopamine, and serotonin are three major chemical systems in the brain influencing depression. - Epinephrine/norepinephrine relates to psychomotor defects, dopamine to anhedonia or lack of pleasure, and serotonin plays a role in mood regulation. 38:04 🧠 *Neurotransmitter Systems in Depression* *- Norepinephrine: Related to activity and alertness.* *- Dopamine: Related to motivation, pleasure, and seeking experiences.* *- Serotonin: Linked to grief and emotional aspects of depression.* - Connection between thyroid hormone and depression: *- 20% of people with major depression have low thyroid hormone.* *- Hypothyroidism can lead to low energy and metabolism, contributing to depression.* 44:02 🌬️ *Stress and Depression* - Impact of stress on depression: *- Higher stress levels correlate with a higher risk of major depression.* *- Cumulative long-term stress episodessignificantly increase the likelihood of depression.* 46:26 🧬 *Genetic Predisposition to Depression* - Understanding genetic factors in depression: *- Certain genes, like 5HTTLPR, raise susceptibility to depression under stress.* *- Genetic predisposition increases the likelihood but doesn't guarantee depression.* 51:19 🛠️ *Tools for Depression* - Mechanistic approach to tools for depression: *- Behavioral tools, such as cold showers, can impact neurotransmitter levels.* *- Exercise and specific activities can influence serotonin, dopamine, and norepinephrine levels.* 55:37 🔄 *Accessing Circuits in Depression* - Challenge of accessing positive circuits in depression: *- People in deep depression may struggle to engage in activities that boost mood.* *- Understanding the difficulty of accessing pleasure-related circuits during severe depression.* 56:07 🧠 *Understanding Depression Overview* - Major depression may be linked to excessive inflammation in the body. 57:34 🌡️ *Role of Inflammatory Cytokines in Depression* - Inflammatory cytokines (e.g., IL-6, TNF alpha) play a crucial role in chronic inflammation. 59:30 🐟 *EPA Omega-3 Fatty Acids for Depression* - Increasing intake of EPA omega-3 fatty acids has been shown to reduce inflammation and relieve depressive symptoms. 01:03:50 🏃♀️ *Exercise and Tryptophan Pathway* - Exercise positively impacts the tryptophan to serotonin conversion pathway, countering depressive effects. 01:07:19 🌊 *Common Biochemical Pathways for Mood Regulation* - EPA and exercise operate in the same biochemical pathways as prescription antidepressants. 01:11:04 💡 *Creatine's Role in Mood Regulation* - Creatine supplementation, particularly creatine monohydrate, shows promise in improving mood and treating depression. 01:15:58 🧠 *Creatine and Phosphocreatine System Overview* - Creatine studies used dosages ranging from 3 to 10 grams per day. 01:17:31 📊 *Creatine's Positive Effects and Gaps in Understanding* - Creatine supplementation shows positive effects on mood and depression. 01:18:32 🔄 *Mania, Creatine, and Mood Enhancement* - Creatine has been shown to increase mania in individuals already manic. 01:20:26 ⚖️ *NMDA Receptor, Ketamine, and PCP* - NMDA receptor is a key node for novel therapeutics in psychiatric clinics. 01:25:25 🧠 *Layer Five Activation and Ketamine's Mechanism* - Layer five neurons' activation is linked to ketamine and PCP-induced dissociative states. 01:28:24 🍄 *Ketamine and Spine Formation for Rapid Relief* - Ketamine induces spine formation on neurons in the prefrontal cortex. 01:31:46 🌀 *Negative Affect and Treatment Approaches* - Ketamine and PCP may provide a path for people to distance themselves from negative affect. 01:33:43 🍄 *Psychedelics and Neural Circuit Rewiring* - Psychedelics, including psilocybin, focus on rewiring neural circuits for depression treatment. 01:35:42 🧠 *Serotonin Receptors and SSRIs* - The diversity of serotonin receptors allows for varied effects on different cells and tissues. 01:36:09 🍄 *Psilocybin Effects on Major Depressive Disorder* - Psilocybin increases serotonin transmission through 5H2A receptors. 01:37:39 🧪 *Clinical Study on Psilocybin Treatment* - Clinical study details administering psilocybin to patients with major depressive disorder. 01:39:08 🚑 *Guided Psilocybin Journeys and Relief from Depression* - Highly trained guides play a crucial role in psilocybin-assisted therapy. 01:41:57 🧠 *Layer Five of the Cortex and Neural Circuitry Rewiring* - Psilocybin appears to impact layer five of the cortex, similar to ketamine. 01:43:23 🍄 *Legality, Dosages, and Future of Psilocybin Treatment* - Psilocybin treatments are currently limited to controlled clinical studies. 01:47:41 🍽️ *Nutrition and Major Depressive Disorder* - Carbohydrates and tryptophan-rich meats may act as self-medicating agents for depression. 01:53:30 🍏 *Ketogenic Diet, GABA, and Depression* - Ketogenic diet increases GABA transmission, potentially alleviating depression. 01:54:59 🧠 *Recap of Depression Tools* - Avoid overwhelming pleasure centers to prevent anhedonia and depression. 01:57:23 ⚙️ *Strategies for Norepinephrine Boost* - Discusses the deficiency of the norepinephrine system in major depression. 01:58:20 🌊 *Role of EPA (Essential Fatty Acids) and Exercise* - Recommends a daily intake of above 1000-2000mg of EPAs for mood benefits. 01:59:49 💊 *Summary of Prescription Compounds and Ketosis* - Brief overview of prescription compounds used in psychiatric studies, such as ketamine, PCP, and psilocybin. 02:00:49 🚀 *Podcast Outreach and Support* - Encourages viewers to subscribe, comment, and provide feedback on UA-cam and other platforms. 02:01:47 🙏 *Closing Remarks and Gratitude* - Expresses gratitude for listeners' interest in understanding and treating depression. Made with HARPA AI
Huberman, you amaze me every week. Thank you for using your intellect to educate the masses and your love of science and your personality to make it appealing to all. I enjoy this podcast so much.
I'm watching this today because I don't know what to do anymore. I'm so tired. I've been wanting to leave earth since I was 10. I'm 27 now, I have no job, no money, nothing to be proud of. I fear people will hurt me again so I literally have no friends. I was abused by my dad and his wife as a kid up until I was 16, and maybe this had a impact on my mental state now? I just live with my mom now. I want to do things but I LITERALLY can't it's like an anchor is pulling me down and I can't control it. My mind is in shambles. It's too messy. I have no motivation to shower or wash my hair (gross!) THIS IS NOT ME!!!! ITCAN"T BE. I'm not asking for anyone to feel sorry lol I just wanted to somehow get that off my chest that's all.
Do you try medication, meditation and therapy?? Cuz that could change your life also if you exercise.. it sounds difficult at first but once you force yourself it gets easier and becomes habit / more enjoyable
Thank you! I've started to implement what I've learned from the podcast like 2 months ago, and the results are beyond my wildest imagination. Using cold water during exercise (between sets) not only increased my endurance, but strength A LOT. Not to mention the benefits of using creatine. That made me like 20% more stronger. And the list goes on. This is priceless.
@@rokas201 I have a relatively cold pool right beside my pull up bar. I simply put my palms and lover arms into the cold water for about 30-40 seconds and I also wash my face between sets.
It is hard to find good and reliable source of information usually lost in a mass of self appointed "experts". This one is a jewel a well presented, clear, research based multilayered class. Very informative, enlightening and kind. Delivered with empathy and hope for people suffering from depression and other mental illnesses. I have a degree in medicine and i am now studying counselling. Plus I have loved ones living with depression. Thank you!
In my experience, the most important thing for dealing with MDD from 13-23 was working on the mindset. Although I'd look for nothing else from a neuroscientist, Huberman here completely overlooks the power of the psyche (whatever that may be from a neurological point of view). I get that sometimes the depression just captures you and it can take hours, days, or weeks before you even realise how toxic and flaccid your mindset has become, but there definitely is some stoic truth in the capacity to detach consciousness from your current experiences, recognizing life as a happening, and treating your mental health problems as just another obstacle to be overcome. Live in the present moment and try as your only life task to make the best action/ decision you can in the moment and this will help you. I've found there is always a resource, and always enough respite if you know where to look. Just making the best choice in this moment is the meaning of life.
@@rochelledejesus2894 yeah man I feel you. I've been battling one hell of an episode these past 2 months. It only takes one moment to be present though, and it's very relieving. It probably doesn't come through via text how much I understand how hard it is. It's completely indescribable.
I've been going to downsub to get the subtitles so I can pour over them and make perfect notes, every monday morning, 2 hour bike ride so I can listen to it all in one go in a focused way. Thank you Sifu! I had lost inspiration for these topics before this podcast, you tell us everything, the whole picture, the whole mechanisms, so we can make our own tools real time, that is beyond my dreams brother
Speaking of creatine and mania - Seven years ago, I had a romantic breakup which triggered a florid manic episode. During this particular episode, my mind fixated on fitness. But it was mania, so it wouldn't let me just become fit. It wanted me to become the most fit person in the world. So I looked up workout programs and supplements. When I began taking creatine, the florid mania went into overdrive. I still wasn't diagnosed at that point, but thank you for this little tidbit. It helps put that particular episode into perspective.
@@mattbabb. Yes, you get it. Factor in hormonal changes, especially since I went from 130 pounds to 165 over the course of around 4 months. Mix that with a preexisting mood disorder and it explains a lot of my behavior around that time.
Thank you so much for these scientifically enlightening discussions and for your natural suggestions, beyond drugs, to help with this affliction. I believe in both, but I generally avoid medications until I've exhausted other options. Both of my grandmothers suffered with depression/anxiety and one was even temporarily institutionalized, was given shock therapy for about a year, at around 35 yrs old for attempted suicide - my mother found her. I believe they, myself and now one of my nieces, are genetically afflicted as I currently am being treated for major depression. My niece will need to be if she continues to refuse to address her lifestyle. None of my ancestral family members had near the information that you have provided - it simply didn't exist. With all the more holistic info you have given us through multiple podcasts, I decided to try to put the pieces together in a daily protocol for myself. I implore others to do the same, because with all of the symptoms that keep us empty and sometimes hopeless, I believe that when we do have moments of 'awakening' we must grab them and design an action plan around these suggestions - A plan in place is much easier to actualize and systematize or habituate. Otherwise, I know I find it too difficult. Peace, Everyone.
Thank you Dr. Huberman. It’s refreshing to find such honest and informative content on this platform. I hope the algo suggests your content well beyond the incredible number of people that need to hear this. Stay awesome!
I'm a therapist and your information is so helpful to my clients who want to understand the reasons behind their struggles. The labeled thumb nails in the podcasts are an excellent way for me to tell clients where to stop and really digest what you are explaining.
!! Seasonal Affective Disorder !! A podcast by you on SAD is much needed. So little is known about SAD, eg. how shortening days results in insufficient norepi, dopamine & serotonin. Nor how mood simply lifts with lengthening days in March. And psychologist/psychiatrist seem to have no reliable protocol of treatment for dopamine & norepinephrine deficiencies, but instead go to standard SSRI or SNRI drugs. This winter I did an effective battle against SAD using NeuroAcoustics, endurance indoor exercise (lap swimming & cycling: hour per day) and dawn viewing (first light until sunrise).
52:22 “when you understand mechanism, it puts you in a tremendous place of power to work with your system. So it's not just plug and chug, like take 12 milligrams of this, you either feel better or you don't. You can really start to understand how prescription drugs, supplements, nutrition, behavioral tools, how those things weave together to either work for you or not work for you and get you to paths of healthy mind and body.”. This is exactly what I am trying to do and thank you God for Andrew Huberman, and the guests that he has on this podcast. I’m not finished with myself yet, but I am making exponential improvements every day. ❤
You are helping so many, just by being your self. Thank you for all of your work, providing free, incredible, available, trusted science. Powerful stuff my friend.
I studied Gaelic for three years, and several of us students found it difficult (at first) to understand Irish expressions of states of being. Emotions are not inside us, they are "on" us. When you were discussing dissociating from emotions by using certain drugs ... it seemed to echo my instructor's attempts to explain the difference between "I am" and "I feel".
Wow you are honestly incredible. Ive been a fan since day 1 and recently I moved to a new city which due to the fact that ive been socially isolated for 2 yrs and I know nobody here and I had some pretty depressing days for the last month cuz I never felt so incredibly sad and wanted to just end everything for no reason. and just when I was like what can I find online to help, andrew returns with yet another banger. this man is a blessing to us all
I have dealt with depression for over 10 years. Not sure what the future holds for me but I hope one day I'll make it out for good. Appreciate the video Dr Huberman and I'll be adding your protocols to my war chest in my battles
I've listened to several episodes of this podcast. They've all been helpful but this one literally saved my life. I can't thank you enough for sharing this knowledge.
This is the first time ever for me that depression has been explained this way to me....Someone very close to me exhibited all the signs articulated here. I hope they received the help they needed.
Incredible discussion on depression. Alongside IBS, I’ve been suffering on and off with it, from mildly, to moderately to severely, since 2006, and am very encouraged to start supplementing with EPA while also consuming more fatty fish. I wouldn’t mind trying micro-dosing mushrooms too. Depression can really ruin much of one’s life!
Just LOVED this content. I've been to psiquiatrits, hematologists, endocrinologists and 3 years later tested my iidine levels and it was really low - I actually had hipothyroidsm due to iodine depretion and fluoride intoxication. Nursing mothers have a greater need for iodine and I've nursed my oldest for 4 years. The link between hipothyroidsm and depression should be enphasised for those 20% in medical practices.
I can’t thank you enough for this episode. 🙏 suffering for more then half my life with auto immune inflammation and been trying to cope with depression as best I can.
I have dealt with my internal inflammation, i think, but am still insulin-resistant. Working on that... and I have been coping with bipolar. Pls join us in the FB grp "Notetakers of Huberman Lab's Podcasts."
Nailed it. Dang, that description of the symptoms sent me right back there. Thank god for medication and my friends and family. You feel like I may not end it but I can’t live like this. So grateful to be alive today.
Firstly, I'm in love with the way you explain neuroscience and I get so excited to learn when you post new monthyl videos ❤ Secondly, this is THE video I've been waiting for because I had suffered from major depression throughout my childhood up until about 2.5 years ago. I was on medications (a couple you mentioned) for about a decade and then I had a traumatic medical event almost 3 years ago (lumbar disc herniation, cauda equina syndrome) that has left me partially disabled. I have spent the last 2.5 years changing habits, getting completely off medications, eating whole non processed foods, eating fermented foods, getting regular exercise, taking supplements (a couple you mentioned), experimenting with psychedelics that all started with DMT and I completely believe that has saved my life (I take 1-2 grams dry psilocybin mushrooms a month, 200 micrograms LSD 2-3 times yearly), ingest cbd almost daily (smoke or tincture), ingest thc once a week or every other week (smoke or edible), embracing spirituality (Hindu beliefs), Journaling and making lists, and seeing a counselor every month just to vent and get unbiased insight. My life is busier than it has ever been and I'm the happiest I've ever been, I completely love and accept myself now. Depression definitely runs in my family so I explore every option to keep it at bay, and it all works 💯 I will definitely be sharing this video on social media and I'll try extra hard to get my family and friends that suffer with depression to seriously give this video their full attention. I look forward to your future videos (especially more about psychedelic and ketamine medicine) ✌
When I had a clinical depression I used to run around 50 miles a week. Every time I told myself “it must help my depression” but after every run I felt more and more exhausted both physically and mentally. Going for a run added more stress and anxiety because I expected it to heal me but it didn’t. Then I started blaming myself for not training hard enough which worsened the symptoms of my depression even more. Eventually I started meds which helped me to get back on track. Exercise, diet, and meditation might help but when you’re so deep into depression it might be useless
I suggest walking. Running outputs a lot of adrenaline
@@MrBUGS713 I'm going for 30 days
I absolutely agree, same was with me neither sport nor meditation helped me, only medication saved my life... but I was in to deep
i come to this conclusion due to going through the same experience as you. i think what happens is you associate the pain from running to the internal pain your experiencing, for me it was a relationship breakdown . what happens to me was over time when I trained i felt the pain of depression from the breakdown of my relationship when I wasn’t feeling too depressed. This made me realise how powerful and heavy depression is. it clinged to the things that actually made me feel good and become the association.
@@IdontspeakBro. I’ve never thought about it this way, but it makes perfect sense actually. After my depressed runs I quit running for quite a while because I probably must have linked it to all these painful emotions. Thank you for your thought. That made me look even deeper in what was going on back then
- cold shower
- exercise (aerobic or strengh training)
- anti-inflamatory diet
- Omega 3 (diet + supplements) 1000mg EPA
- creatine ( 1 gr - 5 gr)
- keto diet
- NOT OVERWHELM THE PLEASURE SEEKING
My son had Schizophrenia..He took his life in 2019..I currently am suffering from chronic depression and severe sleep disorders..i am alll over the place...😢Thank you for having this channel and helping people like me..there is no end in learning...❤
I am so sorry you experienced that :( I will hold you in my heart and pray that you may experience some peace soon. Maybe find a support group for those who have a similar experience to subside some of the loneliness.
I am so very sorry 😢. I lost my son and went through that too. It has taken a long time for me to come out on the other side but it did happen gradually. Keep loving yourself through and practice self care. So very sorry, truly a nightmare. ❤️
Mais MS
my dad had schizophrenia too . He passed away from a heart attack at 60 . I’m sorry for your loss and immense pain ❤. I do yoga nidra and celeapram helps heaps for my anxiety .. i loved my dad but schizophrenia took over . bless you ❤
Sorry for your loss, something that helped me cure my depression and negative thoughts is a supplement called 5htp , it increases serotonin in your brain and helps see the brighter side of things. Please look into it, it really helps with depression and sleep as it increases melatonin. I take 150mg per day. Do not take it with other antidepressants SSRI's which can cause too much serotonin in the brain called serotonin syndrome. 5htp doesn't have any of the side effects antidepressants do. Hope it helps, sending you prayers 🕊
Dr. Huberman your contribution to humanity is substantial. Humans being able to work at maximum potential is a beautiful thing and your work is making that possible. Thank you sir !
For real. I hope his parents are proud.
to live at maximum potential ;)
@@philosorapper5454 they fucking better be haha. This man is the ideal man. He is everything I am not and I love him for it!
Humans destroying their home planet at maximum potential…. not sure if thats such a good thing.
@@brucewayne4160 If not, they'd missed it! Simple as that ;)
This podcast is one big reason I have come out of depression and feel so much better. I get my sunlight, eat my omega 3s, vitamin d, ashwaganda, and L-theanine and I’m speechless at how big of a difference it’s made. I’ve stopped crying and falling into despair, and upsetting things aren’t a tsunami of sadness anymore. I cannot thank you enough. May God bless you and your efforts.
(The other factor that helped is PickUpLimes video about feeling lost, and using the printable worksheets she gives to find out what my values are and living according to those)
I'm watching this episode again & read your comment. I take the same supplements that you mentioned. I was just wondering how you feel now.
Be careful with ashagawanda the long term effects you start to feeel no happiness
@@sweetest247 I hope your doing okay i just said a prayer for you. 🩵
The tide of war has turned.
@@sweetest247 I believe in you you can get through anything I’m sending my prayers for you
As someone battling with severe suicidal depression, when he says “it feels like a pit that you can’t get out of” is exactly how I feel.
It's a good description I agree....when suffering the same, I found even breathing laborious. Hope you're feeling better ..best wishes 🙏🧡
bro how are you coping? Can you share if something worked
I hope you are doing better. It’s horrible
@ I am not but I appreciate you asking. You are right; it is horrible. I am beyond exhausted from fighting. I ask that God lighten your burden if you are dealing with it. May you find peace, love and joy again. Take care.
@@hofahome 🙏💙
6 pages of notes. I feel like a Standford Student. Thank you Dr. Huberman for providing us all with this FREE, potentially life saving information!
Any chance you could share some of the notes??
@@ckstevenson I was thinking the same thing lol
I am so grateful that Dr. Sapolsky has a someone so worthy to follow in these footsteps of sharing needed knowledge
It’s all in the video
this video didn't touch on what depression actually is, or how to get rid of it. it attempted to use hard science to explain and solve a basic metaphysical problem. its not that complex, philosophers who didn't have access to electricity broke it down better 1000 years ago. depression is a state of hopelessness. example "grandma who I loved so much is dead and she's never coming back", "it's too late to get a higher education and better my life I need to work a terrible job forever now", "im unhappy in marriage but need to stay for my kids". these are the types of internal dialogues that cause depression, SPECIFICALLY because your subconscious feels hopeless. it may not in reality be hopeless but that's your perception. spend 5 hours alone in a room with nothing but a pen, paper and your thoughts - it will be scary but you'll gain clarity. either that or go see a shrink who can help you explore what you feel hopeless and chronically anxious about. this guy is a goof.
I love that Huberman truly does stick to the science. Nothing really philosophical, moral, nor opinion based. Purely fact driven. It’s such a breath of fresh air.
science? more like bad science! almost the whole video is antiscientific. The seretonin/depression myth has been busted just last year by Dr, Joanna Moncrieff. do your research. psychiatry is back to 1950 again
As someone who suffers with extreme severe anxiety I can totally relate to her. I would stop eating for days at a time as a punishment. I worry a lot about my life, everyone around me and pleasing everyone. It's absolutely crippling, so glad she got the help she needed, lovely young lady it's so sad that society has 1 in 3 people suffering mental health issues. I hope everyone seeks help
People need to realise that people with anxiety disorders have oversensitised nerves, it's not a simple case of manning up and getting over it.
Can you help with the reliable source I would really appreciate it. Many people talk about how mushrooms and psychedelics treats anxiety, but nobody talks about where to get them. Very hard to get a reliable source here in Australia. Really need!
Yes, doctor Greg mushroom I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.
Please, how do I reach doctor Greg?
Is he on the internet?
This lecture will give me knowledge to support a friend who is suffering depression. Thank you, sir, you make our world a better place !
Bless you 🎵🎵
@@dareartes4232 1111111
@@dareartes4232 1111111111
@@dareartes4232 1
@@dareartes4232 q
I'm almost 40. I would guess I had my first depressive event around 10. Since then I've spent 20 +years casually learning about depression, and never has information come to me in a more digestible, empowering way. I have enjoyed your podcast for many months, but this one feels like it was for me. Thank you!
Please tell me the depression gets easier as you age :/
@@sourgummyworms8069 knowledge is your friend, use it and it will get easier. The fact that you're watching this video gives a good indication of that.
@@sourgummyworms8069 I think it depends on circumstance but if you learn to love yourself and others despite their actions, it will get better ,and, forgiveness of others will inadvertently heal you in the process.
Tone back the empathy
@@MrBUGS713 your lack of empathy is probably why youre depressed
I’ve had severe depression, getting out of bed feels like jumping into an ice lake, eating breakfast feels like eating feces. And the intensity of these feelings can vary all over the place, you cannot plan anything because your perception of reality can change just like that. What in one second felt like a nice walk in the country, feels like a stroll down a never ending corridor
We need more dopamine:-) hang in there. You are love
I am going through that now. My therapist just sent me the link to this video. But you are so right. It feels exactly like you stated
How do you feel now?
I'm watching this episode & read your comment & just wondering.
@@HelpfulRebelsTVbut from where we should get this extra dopamine. From addictions...
Lamictal and ketamine infusions helped me
I suffered from depression all my life. At about 55 years old I took a food allergy test which showed I had a gluten/wheat allergy. I removed wheat from my diet and after about 2 weeks I was depression free. If I accomplish nothing else in my life, I am depression free.
That is HUGE!! Congratulations!!😁👍🏽✌🏽❤️
You was lucky
Holy shit man. Job well done
fake
Anxiety: Everything is important.
Depression: Nothing is important.
ADHD: I have no idea what's important.
Profound
Yep
What will be anxiety plus depression ?
Anxiety plus adhd here
Schizophrenia: I hallucinate important things all the time.
Bipolar: WHAT DO YOU MEAN ITS NOT IMPORTANT!?!?... never mind... i dont care.
Narcisistic personality disorder: In truth, I am the only really important thing in existance.
I’ve become hooked on your videos this year and while others (doctors) in other professional fields have more credentials on some of these things. Your insight in these podcasts has been satisfying a lot of my curiosity over the years from my depression to adhd to my anxieties on nutrition and caffeine. So many bouncy thoughts roll through my brain from a speed from 1-100, one of my Monday highlights (an off day) and also satisfies me when I’m feeling restless when it’s slow at work. Would love to hear caffeines effects on depression/adhd, or if there already is one. You’re arguably the smartest person I’ve heard talk about anything!
You felt better when stopping caffeine?
I live in Norway, and it's been common practice for 50 years, for society to promote consumption of Omega-3/EPA's, especially to help with seasonal depression due to the darkness/climate. In addition the promotion of good work/life balance, which generally leads to less long term stress - this is a powerful combination.
What forms of consumption? Fish or what specific supplement brands do you guys utilize
You are a true ACE* for humanity!!! Your *ALTRUISTIC/COMPASSIONATE/EMPATHETIC* nature and contributions to make neuroscience more accessible, in order to improve lives, is a true gift to humanity and the future. Thank you
Literally life saving episode. I'm just tuned in because I'm really struck by depression right now. And for someone who is described as a person with lot of positive energy, mental strength and kindness facing with this is really impossible to realise...
👆👆 look up this handle for psilocybin products l recommend for anyone looking to try it Thank me later..
Hang in there and keep listening
I had a serious episode of clinical depression. What I learned is to get care at a public, academic hospital asap.
❤
Thank you soo much for this. My daughter has been suffering from severe depression and your discussion is a god send. People, family especially tend to find it difficult to believe the physical aspect of depression on a person. They call her lazy and mentally weak for not knowing how to deal with stress. They say just suck it up what you're feeling isn't real you just want to deal with difficult aspects of life. I can now share this video where you thoughtfully and thoroughly dissect depression in a way that is understood and for me personally you give me hope. My daughter has tried to take her life 5 time now and is just turning 21. Thank for this gift and please continue to shed a positive light on mental illness and bringing hope to those who struggle from it or are directly affected by it like myself who as a parent wants their child to thrive and find happiness. Than you again!
You are a lovely parent. Best wishes for you and your daughter. I have depression but never suicidal. It is a terrible illness. ❤
Is she better? Depression is hard for everyone, sending love and hope you guys are okay!!❤️
Thank you! We're blessed She hasn't had an attempt in about 2 years now. She's far from being better, still a lot of bad days but with more strategies we learn of, the more tools we have to turn the darkness off or at least silence it and have the will power to continue being consistent. She's working in the mental health field now and is in her 3rd Year of college. Always be Blessed to have the ones we love by your side every day you have a chance.
Explain to them that telling someone to “suck it up” or that “they’re mentally weak” is like telling someone with cancer to just suck it up. Depression isn’t a choice it’s a mental illness
Has she tried a carnivore diet
I've suffered depression probably my entire life. Especially since I got my diploma. The fear of failure, the expectations, the feeling of being lost has caused me depression for years. I sleep too many hours and I wouldn't need all those hours to be honest, but I feel exhausted. When I trip I notice different habits and improve my sleep schedule. Thanks for being a positive energy in my life Andrew
Your voice is easy to listen to & even if someone is depressed, your message comes through. Teaching is your gift.
People who suffer from mental illness are often called out for not wanting to get better. I'ts incredible to see how many people watch dr. Huberman' videos and thank him for saving their life. Looks like people WANT to get better, just didn't know they could.
I REALLY need to get better from depression to take care of my husband and my two kids. I'm irreplaceable for them. We actually want to grow our family. I also have so many projects to accomplish. But how could I if depression kind of forbids me to simply brush my teeths or take a bath?
All the knowledgment that dr. Huberman shares for free is helping me improve my treatment significantly. So THANK YOU, dr. Huberman! You're a life savior. God bless you!
I've been on anti depressants for almost forty years. Tried to get off them many times and eventually gave up. I was severely depressed by the time I was 14 years old. No one ever tried to help me manage the disease with nutrition, exercise, and supplements. I'm glad the science has advanced.
Good to hear, I’m happy for you. Which supplements and diet worked
Doctors are pretty clueless.... I've been hurt by my meds and doctors just think I should take them
I still take 30 mg duloxetine. Arthritis keeps me from getting off the last 30mg- I am in pain all the time. I don’t take anything for it. Long term use of ibuprofen almost killed my mom (stomach bleed), so I know it’s not good for chronic pain. Waiting for Medicare to start so I can at least figure out how bad my bones are. They wanted to fuse some discs thirty years ago and I said no. I made it this long, but it’s gotten a lot worse.
@Bioman Smith I was able to cut the dose in half, but the depression came sneaking back. And then, it roared. I'm in the process of increasing the dose, and starting to feel better again. It is what it is. I don't drink alcohol anymore (quit a few months ago), but I've become a bit of a pot head. 😏At least I'm on the down hill slide (senior citizen).
How are you now?? Still on antidepressants..did u take it everyday or is it on or off
I think if I start treating myself like a friend that I truly love and care for, I will be a better me especially in the long run.
I was diagnosed with neuropathy pain caused by depression. I went through four months of antidepressant treatment that helped me sleep, but that's all I did. At the beginning of the year, I set out to get on my feet and started looking for answers, and that's how I came across this podcast. In the last two months I have applied many tools learned here. It's not a day when I don't have muscle aches, but every day when the pain is below 5, on a scale of 1 to 10, is a good day.
Thank you Dr. Huberman
@@andreabakacs9804 I wonder if you tried CBD? I have thyroid depression and CBD helps me a lot.
@@andreabakacs9804 You're looking for hard scientific answers to basic metaphysical questions. Great philosophers of the past are 10x more intelligent than the average modern scientist. They have more practically knowledge about depression, can accurately describe exactly what it is and how to solve it. To do that you'll need to climb up through hell, so it's not a surprise most people just want a pill. If you actually want functional solutions go look up depression from a philosophical perspective..
You must increase your blood volume and make breath exercise to increase your co2= muscles will
Be finde than.
@Andrea Bakacs please try the medicinal mushrooms either lions mane or Turkey Tail. Changed my life!! Fibromyalgia, chronic fatigue, adhd depression and anxiety. X
Google Alan Gordon and somatic tracking. Also the podcast "tell me about your pain". Maybe it'll help you. New approach. Good luck.
Thank you for pushing to make information like this accessible to everyone, it really means a great deal to alot of people, especially content with this amount of depth and cover. This very video finally gave me the final nudge to make my appointment with my GP to get my symptoms checked on. I've had depressive symptoms on my shoulders for almost 2 years now and I hope this can help. Again, thank you for what you do, and without videos like these I don't think I would be able to make the steps I need to take on my own. You've probably moved thousands to do something similar, whether it is taking that step, or making them aware of what they might have on their shoulders too.
Good for you, I really hope you were able to get some help and answers. Taking the first step and talking about it is the hardest.
@Josie Adams
thank you!
I was able to get some help, I'm on week 2 with my Prozac prescription, and I'm starting therapy in 2 months.
The first step was definitely difficult, but I really do think it'll be worth it in the future
Your mindfulness while speaking and selection of appropriate words with the phrases of clarifying those words on the sides it's just unreal.. It shows how thoughtful you are while creating this podcast.
Greatly appreciate your work❤
OMG I wish everyone would watch this. I am judged daily by people who believe I just don’t want to get better because I don’t work out and cannot keep a regular sleep schedule (including doctors!). For one second I just want someone to see how it feels to be judged for not working out when you can’t brush your teeth. Or to go for a run when your leg is broken. What people do not understand they use to blame those stricken. It’s terrible.
True
I am a dancer. since I am in depression I simply can't move. I am freezed...
Thank you
I find it interesting to hear emotion tied in with depression because when I had MDD I didn’t have emotion, I didn’t cry I didn’t feel sad I felt complete nothingness, a shell of a human. Oh also the exercising thing from earlier on, that depressed people lack motivation to go for a run, it feels physically impossible, we don’t lack motivation we just feel like we are slowly dying and standing up is at times too much. That’s why so many people with depression sit in the shower
How are you now?
When I'm depressed, getting in the shower is the last thing I wanna do!
@@carynmartin6053
If you work you likely have to do it but for me yes it is soooo hard however once I do it when I have any urge it makes a world of difference for me & just leaving the home in my car. A drive. I think it is vital however for you to make that decision when your ready. It doesn't help when another tells you. If you have that shut it out. It is like telling an addict to stop. Sure they may even decide to stop temporarily but they relapse for many reasons but being forced into something is just going thru the motions usually for another. You take full control over your depression, your mind & body. That means your time. Try 1 just one small thing & a shower is a great place to start. If you don't feel well after then rest then start again. Really small steps. One step at a time. 🙏
Damn, I could’ve written this
@@carynmartin6053sometimes people with depression will take multiple showers as an escape from reality.
I want to express my gratitude for this, Prof. Huberman. Since the day you announced that you were going to start a podcast, I have been waiting patiently for an episode on depression and here it finally is. One always has an eagerness to know of one's own afflictions if there is a will to get better. Thank you so much.
Hubie, youre the man. U alone are helping me understand how to become the best version of myself
A nickname I haven’t heard since grade school… ha! Thanks for the feedback!
@@hubermanlabthank you sir! You’ve inspired me to learn as much as I can, to fix myself or learn how to best care for myself, and have motivated me to go back to school, surround myself with academia and to, hopefully, give back to those around me. Seriously a fantastic role model
Hubie?
@@debralbungermd8804 Huber
@@hubermanlab how about (tHe) Uber Man?
im struggling right now and andrew has helped me more than the hotline has. he gives actual steps, the light at the end of the tunnel. i hope to thank him one day
I hope you are better 🙏🏼
50:50
Cold showers
Pshysical Excersice (180 min zone 2 cardio)cuando no podes hablar bien
Suplementar ácidos grasos
Creatina 1:13:00
1:59:00 Fermented foods
“What You Seek Is Seeking You”
Thank you for this episode, at this perfect time..
Exactly
That two-dollar philosophy lesson could just be translated as the algorithm working as intended, assuming you've searched up depression- and neurology-related content before, and maybe other health stuff and channels that the people who watch Huberman have watched.
Damn near jumped off a bridge yesterday and this pops up in my recommended to day. Cried like a damn baby
@@smallswideawake try to follow the tips of dr Huberman, I hope you feel better!
@@nakkiel7 thanks dude, hope you’re having a good one as well :)
I cannot pay attention to his lessons for the whole hour and half he speaks. Its because of my chronic depression and chronic resulting laziness. I still appreciate what he is doing with his time. Social media is a poison. But things like this. Some youtubers. They make me feel like internet really has made life for some people better. Especially underprivileged people with no formal education or the availability of these discussions in their lives.
Huberman has connected millions of people all over the world into a community of self improvement. Real science based self improvement. Making our lives better has never been easier. I am grateful to exist in this time and in this place right now. Thank you Dr Huberman. I hope one day you realise the utter magnitude of people you are helping all over the world.
You're helping so many people with this information. This is just what the internet needed, and it only took it about three decades
🥳
Been there, diagnosed with clinical depression few years ago. For me it was running and reading that saved me. Thank you for the material and some insights that I had in this podcast. Keep it up
Would you consider yourself « cured » or « free » from depression ? I just need some hope with some positive testimonies of people who overcame that. Thanks
@@Zezeguizee I have suffered depression. My best advices to you: 1) Do exercise. Lift weights. 2) Don't take things personally. 3) Improve your relationships. 4) Practice Gratitude for what you already have.
@@Zezeguizee 5) And keep going! No matter how unbearable life seems to be as long as you stay on course you will get better!
I'm bipolar, and this year Andrew saved me with his podcasts... it gave me hope to try to help myself. Pls join us in the FB grp "Notetakers of Huberman Lab's Podcasts."
@@Zezeguizee Yes, i consider myself not only free but so much more powerfull than in that period because now I know hot to detach myself in a period that is going to happen something similar.
As a paramedic from Australia, I continue to learn from your amazing podcasts.
I listened to this episode and I sobbed. I've been through years of depression, it's hell. But there's always science and it has helped me all these years. Thank you Andrew , for so many of us your voice inhibits the re-uptake of serotonin better than any pills.
Poo
I love you babysitting we’re safe love
E yes e e
Pw
W we wee
Ohhh wonderful to hear him say, "...loss of loved one or a pet..." I like him even more for recognizing the importance of the human-pet bond. 💙
He's recently lost his dog Costello whose snoring used to be the background noise for these podcasts.
@nackedgrils9302 Thanks so much for letting me know. I hadn't been able to listen lately. My deepest condolences to Dr. Huberman. I know the loss--all too well. Rest in peace, Costello🙏🏽
@@candacecrute9313 Costello was a good boy
We dont have to go to next star in this Universe to find out that we are not alone on this Earth.
That's what sent me down my latest spiral was losing my best Kitty friend of 23 years a year-and-a-half ago. The last few years of her life I was just living for her to take care of her and make sure she was comfortable and well taken care of. Now I feel completely spun out and literally all alone. I got other things going on that are pressing on me but that was the major catalyst. I keep thinking I'll surface again but these are dark dark days. It doesn't help that it feels like the world is crumbling all around us as well.
I had an experience that surprised me. I am 74 and wanted my testosterone checked. The free testosterone was low. I started taking androgen gel. What surprised me was the impact on my mood. I did not think there was a problem, and am already taking Zoloft. But after staring androgel, my mood was significantly impacted. Particularly in the sense of much less easily irritated. And generally enjoying life a bit more. Probably less anxiety
The greatest thing about all that you've said throughout this sessiom is - you've made it clear thst those who are actually depressed or close to being so, are most likely not at fault for it. The opposite of what they feel like.
You give them hope that they can get better amd that it often doesn't even require medication to achieve that goal.
Thank you for this extensive, very informative and uplifiting session, I really appreciate it, as do many many others without a doubt.
Dr. Huberman we are speechless about your knowledge , I am MD but when to your speech I can see clear pictures that I couldn't see before and was my questions , your are the greatest of all and I can say we all love you for your work.🙏
Andrew is a blessing to the humanity
This Andrew. But the other Andrew is not.
@@elainego5728Who's the other one?
@@IIT24Aspirant Andrew tate
I listened to this and found I was doing most things already.(not the drugs) My biggest trigger is low energy. I went out and bought some creatine and the effect is just amazing! I have been taking 2.5g at breakfast and 2.5g mid afternoon. I am the same happy energiser bunny I was in my youth. I am 65yrs. No procrastination or scrolling. Yay! Thankyou so much!
You should check your methylation in that case (Vitamin B2, B12 and folic acid) are all needed for creatine synthesis
@@mosalami1548 thanks for that! I did that and have added Floradix. It has B1 B2 B6 B12 and Iron. Gave me an added boost 😊
I love this community. Smart empathic people helping each other out to be the best. I will try out creatine. This is my problem rn.
@@trudibarraclough478It helps to be mindful when supplementing with B6 because even though it's water soluble it does get stored in the body. My daily multivitamin and protein shake contained B6. After 6 months of taking both I was diagnosed with B6 toxicity. It seems many "popular" protein shakes, energy drinks and hair/skin/nail supplements add vitamin B6. :)
Wow, I am going to try that. I am 65 as well. Thanks
A lot of depression comes from being abused or neglected, especially as a child. If you weren't given attention, love and stability by 2 parents then you're screwed. I feel like a broken human to the point I sabotage possible relationships and love because I'm afraid it's going to hurt me or them and also I'm afraid of being loved because I don't really know what and how is it like while somewhat longing for it?
It's weird to be human in such circumstances and exhausting I numb myself out with video games and internet, occasionally weed.
I’m not discounting anyone’s traumas, childhood or otherwise. We all have them. This is human, welcome to life. My tenets have been: Lose the blame, it’s pointless and leads to victim hood and resentment, anger, etc. Realize that when you judge something or someone, it will mirror your action at some point, and use that for self reflection to bring awareness to your own choices and actions. Forgiveness. I can’t stress this enough. Of self and others. Become an observer of humanity. When you understand others, you will come to know yourself on such a deep level that you become the rock. The tree. The ocean. You will be able to feel so deeply, and cry at what’s painful and beautiful and you will come to learn it is all the same. You will be able to laugh at yourself, and with yourself, which in turn lightens your load and everyone else’s. Love deeply and wear your heart on your sleeve without fear of abandonment and rejection. You plant seeds and your energy goes out. Be kind. Everyone is doing their best, whether you think so or not. 🌿🤍✨
You're sort of right but not all forms of depression are a consequence of trauma. You should read "the body keeps the score" by Bessel van der Kolk.
@@febbone i actually bought this book not long ago and couldn't find time to read it. Thanks for a reminder
Same. Gym addiction (healthy) is my current substitute/treatment mechanism.
I'm so sorry you have been thru so much but don't despair there is healing. It's very good that you are aware of things. I pray you find the best tools to forward your healing journey.
I almost fell out of my chair when you mentioned tryptophan converting to a neurotoxin where there is extreme inflammation because every time I take it, instead of becoming happier, I'm more depressed and anxious. This is fascinating stuff. Thank you for shining a light on something that has been baffling me.
Thank you for sharing this, I was almost about to start supplimenting with tryptophan. Now that I know what the pathway is I am not about to do that because I can tell there is quite a bit of inflammation in my body right now.
Fascinating. Do you know if 5-htp causes this also?
@@Ronaldinho1996 it did for me. 5-htp coverts directly so it is the precursor to serotonin. Tryptophan would have to first be converted to 5-htp then to serotonin. This is why for me personally both of those agents ended up causing more issues than support. :(
I also could not tolerate tryptophan or 5-htp so take SAM-e, or s-adenosylmethionine, and that has helped
@@susanrenick469 that’s really good to know! I’ll explore those! I also started Saffron as that seems to be a bit better
I have witnessed many family members whom suffered with major depression until their suicides. If they had known the science, things may have been very different. Education is key to modifying patterns in our lives and your podcast is initiating real change in the world. Thank you Dr. Huberman : )
lol thats so stupid to think some scientific protocols that slightly alter your diet and habits are going to solve suicidal thoughts. it's a much bigger picture than just biology and isn't so easy to fix.
I am currently severely depressed and I had to muster a lot of strength to start listening to this. I hope it's good of any kind ❤😢
Hey, how are you feeling now?
I really hope it’s better
Sending you love, my friend. Congratulations on taking the step. 🤗
I hope you’re better. Been there & understand. Many prayers for you. 🙏🏼🩷
You will get through it! Stay strong
Are you feeling better?
After a major stressor 4 days ago and being in what you called a vegetative state ever since, I started watching this. I just took 1600 mg of EPA/DHA 1:1 and 5g of Creatine and I feel like I can maybe go take a walk. Thank you! ❤
Fantastic!!
I experienced the same!
That May temporary help but it’s just a temporary solution. Depression literally damages your neurons and your brain.
@@StunningTransformationshis person isn't experiencing long term depression, so if it's working immediately and they are no long depressed, it has worked. There would be no damage. In any case, the brain can always heal given the right conditions.
Did you take the creatine & if so what happened?
@@nataliebutler well said. When things get better, brain recovers from anything and neuroplasticity is fantastic
Great episode. My comment regarding crying: quite often people living in depression do not cry at all. Even during the hardest experiences. They are like frozen. Do not process emotions spontaneously. Only by revealing the past traumas, and crying them out they can heal and start enjoying life in its all aspects.
And for some crying happens quite a lot, and the numbness comes after the breakdown.
very good advice. I noticed too that I cry very seldom but now I try to do it regularly because It really helps and it's freeing. It sounds maybe weird to say "cry more often" but it actually is beneficial
I cannot thank you enough for your work and contribution to society. Thank you Dr. Huberman. You are one of the most important voices heard today.
After realizing that I am a pile of tubes with various chemicals inside, with two pieces of brain pushed out so my brain doesn't have to sit in total darkness. Knowing that what I feel as happiness, it's just a flood of serotonin in my system or sadness - a dopamine drop. That knowledge is liberating in a weird way.
"Christianity invented the notion of free-will ~ in order to find us guilty!"
Applause! Incredible job Dr.Andrew Humberman. I myself suffer from clinic depression for the last two and half years , tried therapy and medication but found no major relief . I gained a lot of insights about depression backed my scientific evidence. I hope it will change many people lives for better. Keep it up man
Dr. Huberman, you are an angel on Earth. What you are doing is so huge and important for everyone! Thank you, you are immensely appreciated! 🙏🏻
These podcasts are priceless thank you
Not only priceless, but they're FREE too!
P. T. S. D. From childhood often causing chronic depression in adulthood. It's often neglected in families because of denial and shame. Mental illness is now so common that it's acceptance is very common but under treated. Get help with issues like these and have a satisfying life.
Just watching and listening content like this episode alleviates my symptoms. Everything about the pleasure-seeking, pleasure/pain imbalance, and anhedonia were especially enlightening. My emotions, actions and everything makes sense now, and I don't have to blame myself for just being miserable. You also describe many things I've found useful in battling my demons.
Dr. Huberman, you have an excellent understanding of how depression works and are great communicating it clearly, and precisely. What a great man, you deserve much more recognition for your hard work. Thank you so much for sharing the information and your wisdom, everyone should watch this.
You said it perfectly and took the words right out of my mouth
Psychiatrist here - thank you so much for posting such amazing content. This podcast alone has taught me so much. Thank you. Wondering if you could do a similar one discussing anxiety. Would complement this episode nicely. Also discussing relationship between anxiety and depression. My apologies if you have one out on anxiety already and I've missed it!
Tool "Unwinding anxiety" of the psychiatrist and scientist Dr Jud Brewer.
Anxiety as a thought habit loop.
A lot of podcast on you tube from him.
On changing habitual behaviors. Thinking one way or another can also be viewed as a behavior.
I have subscribed to his App and it works.
Better than medication.
Brilliant idea
Anxiety is always the first step of my depression. Irritation -> Anxiety -> Depression -> okay again, repeat
@@KellyandJennaO definitely agree
@@KellyandJennaO ditto
God bless you man. You're showing common people the light by showing them a way out that they just don't have the tools to find themselves.
As a person that doesn't go to a doctor:
- breathing exercises (wim hof)
- thinking of loved ones
- listening to Eckhart Tolle
These are things that actually help me in the moment and bring me through the day
I probably should do them daily, but I don't.
The most organized and comprehensive episode and podcast ever! My dopamine level is through the roof because of the topics of this month. I have been waiting so long for this... Thank you
Glad it was helpful. Thank you!
Very useful episode for everyone, professionals and patients. However, I think a topic addressing the effects of cognitive behavioral therapy would also be really cool!
Came here to leave this exact comment thank you!
Excellent contribution. I’d find that fascinating
Based on my experience I think CBT is mostly effective only when a person resolves the biological component of depression.
Trueee
@@dp26385 my personal experience has shown that you are correct most of the time
just listening to your lecture has made feel better. I feel the anchor of depression what weights me down get lighter. I think it's because you explain the complex emotions and thoughts going through us in a simple way and makes you feel normal.
I had a friend of mine change their diet (meat, veg, spices) and reduce their stress and within 6 months they were off their meds and feeling great.
When I eat standard diet I get depression back straight away. Just like that and can't shift it. When I eat keto, carnivore with fasting I'm happy.
I am bipolar and one of the best time for me was on the ketogenic / carnivore diet that high fat was so good and help me much better than any pills .. I lost so much weight I had to modify my diet , now I am going back on my high fat !!
I'm currently experiencing this as well. Pls join us in the FB grp "Notetakers of Huberman Lab's Podcasts."
Thank you so much, this is exactly the kind of episode I was hoping to see from you. Personally, the biggest improvements I've seen during my history of depression have always come from hearing and understanding the actual science surrounding my circumstances. Not only does it feel affirming to know the neurochemical roots of my own experience - it also gives me reassurance that improvement is possible.
Again, thank you for putting this stuff out there for free. It's hard to come by stuff like it, especially as someone who has - and is still spending my teen years met by mental health professionals who often either don't want to or are unable to offer this scientific point of view.
I wonder how sub-consciously self-sentient the brain is when we learn about these things... Does it help the brain know its self as a functional organ, & influence changes in development to improve function, etc? Lol.
@@Flusterette There's no indication of this being the case. Brain is not a separate organisms which starts gaining it's own conscious (outside of the conscious which we already have), learning about how it functions and thus changing how it functions. Who knows, maybe, but there's no evidence supporting the theory that brain is a sentient being within a sentient being.
What happens here, if you pay attention to what OP said, is that it's not the actual knowledge presented by dr Huberman that made OP (and other people in comments) feel better, but a *belief* that this is true. OP didn't try out protocols for few weeks and started to feel change. They heard that "science says there's a way to fix it and it's curable for everyone" and they believed it on the face value (whether it's true or not is completely irrelevant, eg. dr Huberman could have said that sunning your balls 30min every day has been shown to cure depression in 99.9% of cases and OP would be just as happy).
It's exactly the same as a religious person going to their spiritual guru, who touches, them, says few prayers and they feel much better right away.
That's why there's this interesting paradox where people who don't really understand how scientific method works and that nothing is definite and absolute in science, do feel better applying some scientifically developed method (often psuedo-scientifically), while people who know about those limitations and no method is perfect and won't work in 100% of cases, need some sort of spiritual guidance to feel better.
That's why belief is such a powerful tool, especially when it comes to mental and emotional health.
@@kalash_nikov I'm 100% on the same page with you, just putting out my curious pondering into the void for amusement's sake.
But thanks for taking the time.
@@Flusterette ohmg I wonder the same thing
@@kalash_nikov Thanks for the (indirect) reply. I might not have communicated it quite right, but I’m more so appreciating the combination of protocols and getting served the science of why our current (and extremely limited) knowledge of the brain and body supports that it might work.
Again - my experience is that some (empathizing SOME) psychologists tend to hand out extensive protocols and rely largely on a very “fluffy” and metaphorical version of the mind. This is of course extremely useful - if it wasn’t it wouldn’t be used. Just like you said, belief is very powerful. Psychology works even if we don’t always know why - the most important thing is that it DOES work.
I really don’t think mental health treatment should be based around serving scientific facts. I’m more than aware how how non-definite science is, and I’m aware that my comment was very anecdotally and emotionally based.
I’ve just experiences some professionals talking down to me because of my age. It was frustrating to be told all of these metaphors that I should apply for my mind withtout even just a small hint of “this is actually about changing the neurochemistry of your brain.” I’m not saying this is the case for everyone though and I really don’t hope I come across as a “yay science” type who believes that as soon as my favourite internet-scientist says something, it’s instantly gospel.
But thank you for the comment. It was very thought-provoking and all of your points are very good.
Dr. Huberman I am 82yo and have described you as my guru to anyone who will listen. I have discovered that exercise does help with depression but the important discovery for me is obsessive thoughts leading to depression. Have tried to break myself of that destructive habit which fortunately does not happen often. My mother did it often so I guess there is a genetic predisposition involved. Am just coming out of a mild depressive state now. Always consume omega 3 as supplement and eat salmon several times a week. I would love to have the secret to stopping obsessive thoughts when they do occur. Possibly removing myself from the stressful cause is the answer!! Thank you for what you do to help us!
You create more of them by trying to stop them. Accept and be at peace with it
Acceptance and Commitment Therapy. Also, look into Pure-O OCD.
Thank you from the bottom of my heart for explaining so beautifully and simplyfying it for the public from non science field too
Dr Huberman you are amazing human being.
God bless you !!
I can't wait to finish this!
I just can't believe we have access to someone like you, and have the chance to learn so much from your vast knowledge...it's deeply appreciated!!
He’s a STAR!
I too have become addicted to these outstanding and highly interesting/informative podcasts by Dr. Huberman. I was diagnosed with Bipolar II , yet I feel more like its major depression as I can't think of many times I ever feel joy. I thank you Dr. Huberman and I have ordered creatine and fish oil pills from Momentous. God bless you !! And thank you !!
🎯 Key Takeaways for quick navigation:
00:00 🎙️ *Introduction to the Huberman Lab Podcast on mood disorders*
- Overview of the month's focus on disorders of the mind, including depression, attention deficit disorders, eating disorders, schizophrenia, and bipolar disorder.
- Discussion of psychological and biological underpinnings of mood disorders.
02:00 🧠 *Understanding the pleasure-pain balance in the brain*
- Explanation of the pleasure system and its association with mental or psychological anguish.
- Description of the release of dopamine during the pursuit of pleasure and its role in motivation.
05:23 🔄 *Breaking the cycle of pleasure and pain for mental well-being*
- Discussion on the diminishing returns of dopamine release with repeated pursuit of pleasure.
- Importance of entering states of boredom or non-pursuit of pleasure to reset the pleasure-pain balance.
07:45 🩺 *Sponsorship message and promotion of InsideTracker*
- Introduction to InsideTracker as a personalized nutrition platform.
- Emphasis on the significance of regular blood work for health.
11:33 🤔 *Distinguishing major depression from bipolar depression*
- Explanation of major depression as characterized by lows without manic highs.
- Mention of bipolar depression and its distinct features, which will be covered in a separate episode.
13:01 ⚠️ *Sensitivity and caution in discussing mood disorders*
- Acknowledgment of the sensitivity around self-diagnosis of mood disorders.
- Encouragement to be aware of potential symptoms but to seek professional diagnosis.
14:28 🎭 *Clinical criteria and symptoms of major depression*
- Discussion of specific criteria for major depression, including grief, sadness, and threshold to cry.
- Exploration of anhedonia as a lack of ability to enjoy previously pleasurable activities.
19:19 🧠 *Confabulation in Depression*
- People with depression often engage in confabulation, creating elaborate stories that may not align with reality.
- Confabulation in major depression can lead to delusional anti-self narratives, portraying oneself as sick or not well.
22:10 😴 *Vegetative Symptoms in Depression*
- Vegetative symptoms in major depression are related to disruptions in the autonomic or vegetative nervous system.
- Common vegetative symptoms include constant exhaustion and early waking without being able to fall back asleep.
23:37 🛌 *Sleep Architecture Disruption*
- Depression disrupts the architecture of sleep, particularly affecting slow wave sleep and REM sleep patterns.
- The activity pattern in the brain during sleep phases is also disturbed in individuals with major depression.
26:57 🧪 *Underlying Biology of Depression*
- Tricyclic antidepressants and MAO inhibitors were early drugs relieving depression symptoms by impacting norepinephrine levels.
- Discovery of pleasure pathways and dopamine's role highlighted disruptions in the dopamine system in depression.
30:22 🤔 *Complications with Antidepressant Medications*
- Tricyclic antidepressants and MAO inhibitors relieved symptoms but had undesirable side effects.
- SSRIs, while effective for many, present challenges with side effects and varying responses among individuals.
36:39 🧠 *Chemical Systems in the Brain Related to Depression*
- Norepinephrine, dopamine, and serotonin are three major chemical systems in the brain influencing depression.
- Epinephrine/norepinephrine relates to psychomotor defects, dopamine to anhedonia or lack of pleasure, and serotonin plays a role in mood regulation.
38:04 🧠 *Neurotransmitter Systems in Depression*
*- Norepinephrine: Related to activity and alertness.*
*- Dopamine: Related to motivation, pleasure, and seeking experiences.*
*- Serotonin: Linked to grief and emotional aspects of depression.*
- Connection between thyroid hormone and depression:
*- 20% of people with major depression have low thyroid hormone.*
*- Hypothyroidism can lead to low energy and metabolism, contributing to depression.*
44:02 🌬️ *Stress and Depression*
- Impact of stress on depression:
*- Higher stress levels correlate with a higher risk of major depression.*
*- Cumulative long-term stress episodessignificantly increase the likelihood of depression.*
46:26 🧬 *Genetic Predisposition to Depression*
- Understanding genetic factors in depression:
*- Certain genes, like 5HTTLPR, raise susceptibility to depression under stress.*
*- Genetic predisposition increases the likelihood but doesn't guarantee depression.*
51:19 🛠️ *Tools for Depression*
- Mechanistic approach to tools for depression:
*- Behavioral tools, such as cold showers, can impact neurotransmitter levels.*
*- Exercise and specific activities can influence serotonin, dopamine, and norepinephrine levels.*
55:37 🔄 *Accessing Circuits in Depression*
- Challenge of accessing positive circuits in depression:
*- People in deep depression may struggle to engage in activities that boost mood.*
*- Understanding the difficulty of accessing pleasure-related circuits during severe depression.*
56:07 🧠 *Understanding Depression Overview*
- Major depression may be linked to excessive inflammation in the body.
57:34 🌡️ *Role of Inflammatory Cytokines in Depression*
- Inflammatory cytokines (e.g., IL-6, TNF alpha) play a crucial role in chronic inflammation.
59:30 🐟 *EPA Omega-3 Fatty Acids for Depression*
- Increasing intake of EPA omega-3 fatty acids has been shown to reduce inflammation and relieve depressive symptoms.
01:03:50 🏃♀️ *Exercise and Tryptophan Pathway*
- Exercise positively impacts the tryptophan to serotonin conversion pathway, countering depressive effects.
01:07:19 🌊 *Common Biochemical Pathways for Mood Regulation*
- EPA and exercise operate in the same biochemical pathways as prescription antidepressants.
01:11:04 💡 *Creatine's Role in Mood Regulation*
- Creatine supplementation, particularly creatine monohydrate, shows promise in improving mood and treating depression.
01:15:58 🧠 *Creatine and Phosphocreatine System Overview*
- Creatine studies used dosages ranging from 3 to 10 grams per day.
01:17:31 📊 *Creatine's Positive Effects and Gaps in Understanding*
- Creatine supplementation shows positive effects on mood and depression.
01:18:32 🔄 *Mania, Creatine, and Mood Enhancement*
- Creatine has been shown to increase mania in individuals already manic.
01:20:26 ⚖️ *NMDA Receptor, Ketamine, and PCP*
- NMDA receptor is a key node for novel therapeutics in psychiatric clinics.
01:25:25 🧠 *Layer Five Activation and Ketamine's Mechanism*
- Layer five neurons' activation is linked to ketamine and PCP-induced dissociative states.
01:28:24 🍄 *Ketamine and Spine Formation for Rapid Relief*
- Ketamine induces spine formation on neurons in the prefrontal cortex.
01:31:46 🌀 *Negative Affect and Treatment Approaches*
- Ketamine and PCP may provide a path for people to distance themselves from negative affect.
01:33:43 🍄 *Psychedelics and Neural Circuit Rewiring*
- Psychedelics, including psilocybin, focus on rewiring neural circuits for depression treatment.
01:35:42 🧠 *Serotonin Receptors and SSRIs*
- The diversity of serotonin receptors allows for varied effects on different cells and tissues.
01:36:09 🍄 *Psilocybin Effects on Major Depressive Disorder*
- Psilocybin increases serotonin transmission through 5H2A receptors.
01:37:39 🧪 *Clinical Study on Psilocybin Treatment*
- Clinical study details administering psilocybin to patients with major depressive disorder.
01:39:08 🚑 *Guided Psilocybin Journeys and Relief from Depression*
- Highly trained guides play a crucial role in psilocybin-assisted therapy.
01:41:57 🧠 *Layer Five of the Cortex and Neural Circuitry Rewiring*
- Psilocybin appears to impact layer five of the cortex, similar to ketamine.
01:43:23 🍄 *Legality, Dosages, and Future of Psilocybin Treatment*
- Psilocybin treatments are currently limited to controlled clinical studies.
01:47:41 🍽️ *Nutrition and Major Depressive Disorder*
- Carbohydrates and tryptophan-rich meats may act as self-medicating agents for depression.
01:53:30 🍏 *Ketogenic Diet, GABA, and Depression*
- Ketogenic diet increases GABA transmission, potentially alleviating depression.
01:54:59 🧠 *Recap of Depression Tools*
- Avoid overwhelming pleasure centers to prevent anhedonia and depression.
01:57:23 ⚙️ *Strategies for Norepinephrine Boost*
- Discusses the deficiency of the norepinephrine system in major depression.
01:58:20 🌊 *Role of EPA (Essential Fatty Acids) and Exercise*
- Recommends a daily intake of above 1000-2000mg of EPAs for mood benefits.
01:59:49 💊 *Summary of Prescription Compounds and Ketosis*
- Brief overview of prescription compounds used in psychiatric studies, such as ketamine, PCP, and psilocybin.
02:00:49 🚀 *Podcast Outreach and Support*
- Encourages viewers to subscribe, comment, and provide feedback on UA-cam and other platforms.
02:01:47 🙏 *Closing Remarks and Gratitude*
- Expresses gratitude for listeners' interest in understanding and treating depression.
Made with HARPA AI
Huberman, you amaze me every week. Thank you for using your intellect to educate the masses and your love of science and your personality to make it appealing to all. I enjoy this podcast so much.
We, bookworms, literally need a book full of example about each topic you discuss by you professor.
Yes, I really wish he would write a book
He said he is working on a book right now :)
I will preorder his book so dang fast once it is finished! haha
NE, dopamine and serotonin are covered in psycho-pharmacology.
I'm watching this today because I don't know what to do anymore. I'm so tired. I've been wanting to leave earth since I was 10. I'm 27 now, I have no job, no money, nothing to be proud of. I fear people will hurt me again so I literally have no friends. I was abused by my dad and his wife as a kid up until I was 16, and maybe this had a impact on my mental state now? I just live with my mom now. I want to do things but I LITERALLY can't it's like an anchor is pulling me down and I can't control it. My mind is in shambles. It's too messy. I have no motivation to shower or wash my hair (gross!) THIS IS NOT ME!!!! ITCAN"T BE. I'm not asking for anyone to feel sorry lol I just wanted to somehow get that off my chest that's all.
Do you try medication, meditation and therapy?? Cuz that could change your life also if you exercise.. it sounds difficult at first but once you force yourself it gets easier and becomes habit / more enjoyable
I understand you so much! I wish you to find the way out. I’m trying too. Tomorrow will order all these supplements on Iherb
May god bless you
Thank you! I've started to implement what I've learned from the podcast like 2 months ago, and the results are beyond my wildest imagination. Using cold water during exercise (between sets) not only increased my endurance, but strength A LOT. Not to mention the benefits of using creatine. That made me like 20% more stronger.
And the list goes on. This is priceless.
@@rokas201 I have a relatively cold pool right beside my pull up bar. I simply put my palms and lover arms into the cold water for about 30-40 seconds and I also wash my face between sets.
@@rokas201 or just a big cold metal surface to touch
Sorry which episode is this one Alex? Can you provide me detail. Thanks a lot.
@@rokas201 In the 80’s Major gyms in the US often DID ! A cold water plunge pool and dry sauna were pretty standard
It is hard to find good and reliable source of information usually lost in a mass of self appointed "experts". This one is a jewel a well presented, clear, research based multilayered class. Very informative, enlightening and kind. Delivered with empathy and hope for people suffering from depression and other mental illnesses. I have a degree in medicine and i am now studying counselling. Plus I have loved ones living with depression. Thank you!
In my experience, the most important thing for dealing with MDD from 13-23 was working on the mindset. Although I'd look for nothing else from a neuroscientist, Huberman here completely overlooks the power of the psyche (whatever that may be from a neurological point of view).
I get that sometimes the depression just captures you and it can take hours, days, or weeks before you even realise how toxic and flaccid your mindset has become, but there definitely is some stoic truth in the capacity to detach consciousness from your current experiences, recognizing life as a happening, and treating your mental health problems as just another obstacle to be overcome. Live in the present moment and try as your only life task to make the best action/ decision you can in the moment and this will help you. I've found there is always a resource, and always enough respite if you know where to look.
Just making the best choice in this moment is the meaning of life.
People with depression often struggle making decisions and doubt themselves. I wish I could switch my mindset.
@@rochelledejesus2894 yeah man I feel you. I've been battling one hell of an episode these past 2 months. It only takes one moment to be present though, and it's very relieving.
It probably doesn't come through via text how much I understand how hard it is. It's completely indescribable.
I've been going to downsub to get the subtitles so I can pour over them and make perfect notes, every monday morning, 2 hour bike ride so I can listen to it all in one go in a focused way. Thank you Sifu! I had lost inspiration for these topics before this podcast, you tell us everything, the whole picture, the whole mechanisms, so we can make our own tools real time, that is beyond my dreams brother
Speaking of creatine and mania - Seven years ago, I had a romantic breakup which triggered a florid manic episode. During this particular episode, my mind fixated on fitness. But it was mania, so it wouldn't let me just become fit. It wanted me to become the most fit person in the world. So I looked up workout programs and supplements. When I began taking creatine, the florid mania went into overdrive.
I still wasn't diagnosed at that point, but thank you for this little tidbit. It helps put that particular episode into perspective.
I did something similar! Got into the best shape of my life. No therapy quite like getting crushed under 300lbs of iron 😅
@@mattbabb. Yes, you get it. Factor in hormonal changes, especially since I went from 130 pounds to 165 over the course of around 4 months. Mix that with a preexisting mood disorder and it explains a lot of my behavior around that time.
Thank you so much for these scientifically enlightening discussions and for your natural suggestions, beyond drugs, to help with this affliction. I believe in both, but I generally avoid medications until I've exhausted other options. Both of my grandmothers suffered with depression/anxiety and one was even temporarily institutionalized, was given shock therapy for about a year, at around 35 yrs old for attempted suicide - my mother found her. I believe they, myself and now one of my nieces, are genetically afflicted as I currently am being treated for major depression. My niece will need to be if she continues to refuse to address her lifestyle. None of my ancestral family members had near the information that you have provided - it simply didn't exist. With all the more holistic info you have given us through multiple podcasts, I decided to try to put the pieces together in a daily protocol for myself. I implore others to do the same, because with all of the symptoms that keep us empty and sometimes hopeless, I believe that when we do have moments of 'awakening' we must grab them and design an action plan around these suggestions - A plan in place is much easier to actualize and systematize or habituate. Otherwise, I know I find it too difficult. Peace, Everyone.
This is how learning should be!!! These podcast are like gold!! Thank you Dr. Huberman!!
Thank you Dr. Huberman. It’s refreshing to find such honest and informative content on this platform. I hope the algo suggests your content well beyond the incredible number of people that need to hear this. Stay awesome!
Shared with my anxiety group. I can’t thank you enough for all you do. On behalf of all of us, thank you!!!
I'm a therapist and your information is so helpful to my clients who want to understand the reasons behind their struggles. The labeled thumb nails in the podcasts are an excellent way for me to tell clients where to stop and really digest what you are explaining.
Thank you for being a therapist who does this for people
!! Seasonal Affective Disorder !! A podcast by you on SAD is much needed. So little is known about SAD, eg. how shortening days results in insufficient norepi, dopamine & serotonin. Nor how mood simply lifts with lengthening days in March. And psychologist/psychiatrist seem to have no reliable protocol of treatment for dopamine & norepinephrine deficiencies, but instead go to standard SSRI or SNRI drugs.
This winter I did an effective battle against SAD using NeuroAcoustics, endurance indoor exercise (lap swimming & cycling: hour per day) and dawn viewing (first light until sunrise).
Always looking forward to the weekly episode, thanks dr Andrew for the tremendously hard work! These are truly making the world a better place
This is the most info dense podcast I've ever listened to in the past decade.
Huberman legend in the making
52:22 “when you understand mechanism, it puts you in a tremendous place of power
to work with your system.
So it's not just plug and chug, like take 12 milligrams of this,
you either feel better or you don't. You can
really start to understand how prescription drugs, supplements, nutrition, behavioral tools, how those things weave together to either work for you or not work for you and get you to paths of healthy mind and body.”.
This is exactly what I am trying to do and thank you God for Andrew Huberman, and the guests that he has on this podcast. I’m not finished with myself yet, but I am making exponential improvements every day. ❤
You are helping so many, just by being your self. Thank you for all of your work, providing free, incredible, available, trusted science. Powerful stuff my friend.
I studied Gaelic for three years, and several of us students found it difficult (at first) to understand Irish expressions of states of being. Emotions are not inside us, they are "on" us. When you were discussing dissociating from emotions by using certain drugs ... it seemed to echo my instructor's attempts to explain the difference between "I am" and "I feel".
Thank you. My wife is fighting depression now. I shared some information covered here. Her eyes were wide open and she felt understood.
Wow you are honestly incredible. Ive been a fan since day 1 and recently I moved to a new city which due to the fact that ive been socially isolated for 2 yrs and I know nobody here and I had some pretty depressing days for the last month cuz I never felt so incredibly sad and wanted to just end everything for no reason. and just when I was like what can I find online to help, andrew returns with yet another banger. this man is a blessing to us all
🌹
I have dealt with depression for over 10 years. Not sure what the future holds for me but I hope one day I'll make it out for good. Appreciate the video Dr Huberman and I'll be adding your protocols to my war chest in my battles
Omg 10 years… I’m sorry to hear it. U r so strong
Update: I have made it out for good. Life's much better now:
I have a nice job, travel a lot and I have way more exercise so I look much healthier 🙂
thank goodness. can you give me tips how to deal with it ?
@@TheGiraffeJustin
@@TheGiraffeJustinLove to hear it
I've listened to several episodes of this podcast. They've all been helpful but this one literally saved my life. I can't thank you enough for sharing this knowledge.
This is the first time ever for me that depression has been explained this way to me....Someone very close to me exhibited all the signs articulated here. I hope they received the help they needed.
Even before this video starts, I am so happy that this issue is getting covered. Thank you !!
Incredible discussion on depression. Alongside IBS, I’ve been suffering on and off with it, from mildly, to moderately to severely, since 2006, and am very encouraged to start supplementing with EPA while also consuming more fatty fish. I wouldn’t mind trying micro-dosing mushrooms too. Depression can really ruin much of one’s life!
Just LOVED this content. I've been to psiquiatrits, hematologists, endocrinologists and 3 years later tested my iidine levels and it was really low - I actually had hipothyroidsm due to iodine depretion and fluoride intoxication. Nursing mothers have a greater need for iodine and I've nursed my oldest for 4 years. The link between hipothyroidsm and depression should be enphasised for those 20% in medical practices.
I can’t thank you enough for this episode. 🙏 suffering for more then half my life with auto immune inflammation and been trying to cope with depression as best I can.
same..just ordered some 1000mg EPA --
I have dealt with my internal inflammation, i think, but am still insulin-resistant. Working on that... and I have been coping with bipolar. Pls join us in the FB grp "Notetakers of Huberman Lab's Podcasts."
Nailed it. Dang, that description of the symptoms sent me right back there. Thank god for medication and my friends and family. You feel like I may not end it but I can’t live like this. So grateful to be alive today.
Firstly, I'm in love with the way you explain neuroscience and I get so excited to learn when you post new monthyl videos ❤
Secondly, this is THE video I've been waiting for because I had suffered from major depression throughout my childhood up until about 2.5 years ago.
I was on medications (a couple you mentioned) for about a decade and then I had a traumatic medical event almost 3 years ago (lumbar disc herniation, cauda equina syndrome) that has left me partially disabled.
I have spent the last 2.5 years changing habits, getting completely off medications, eating whole non processed foods, eating fermented foods, getting regular exercise, taking supplements (a couple you mentioned), experimenting with psychedelics that all started with DMT and I completely believe that has saved my life (I take 1-2 grams dry psilocybin mushrooms a month, 200 micrograms LSD 2-3 times yearly), ingest cbd almost daily (smoke or tincture), ingest thc once a week or every other week (smoke or edible), embracing spirituality (Hindu beliefs), Journaling and making lists, and seeing a counselor every month just to vent and get unbiased insight.
My life is busier than it has ever been and I'm the happiest I've ever been, I completely love and accept myself now. Depression definitely runs in my family so I explore every option to keep it at bay, and it all works 💯
I will definitely be sharing this video on social media and I'll try extra hard to get my family and friends that suffer with depression to seriously give this video their full attention.
I look forward to your future videos (especially more about psychedelic and ketamine medicine) ✌
Thank goodness
The last two podcasts are right up my street, thank you