15 years after upload, this are still the best tutorials you can find on youtube and they save my a** often during first year of med school. Thanks for ur videos, not all heroes wear capes!!
This was uploaded when I was six years old, and now at 23 I'm using it to study for my first medical school exam. Crazy stuff, thank you so much Dr. Minarcik.
@darlantro Just to add a little more explanation... The blood brain barrier was discovered by Ehrlich who injected dye into the blood and noted it didn't reach the brain, later one of Ehrlich's students injected dye into the CSF and noted the dye didn't reach the blood. (Much) more recent repeats of this second experiment with microscopy show that the endothelium of blood vessels in the brain, not astrocytes are the barrier, as the dye in the CSF reaches the endothelium but not through it.
@radium86 This is correct: to be specific, endothelium is the blood brain barrier. The role astrocytes play in the BBB is their foot processes induce the cells of the endothelium to form the tight junctions that make up the BBB. So if asked "what makes up the BBB", the answer is endothelium, but you should also be aware that astrocytes play a role in it as well, though it is indirect.
I hope no test question would have only endothelium as the answer. Endothelium is present in all vessels. The BBB is also made of astrocytes and pericytes. I wouldn't call it indirect
Thanks ! This video is very useful to me but i still have the problem with the identification of other cell types in brain tissue like macrophage or PMN in the inflammatory response
One part of my histology-exam is a slide test, and if I pick Cerebral cortex I must distinguish the six cytoarchitectonic layers.. Do you have any tips on how I can tell the difference between them?
Cool video! A lot of those small cells are endothelial cells forming vasculature... maybe worth pointing out that they are non-CNS but still in your slice. Also, there are smaller neuronal nuclei (for sure in layers 2,3 & 6of the cortex) so generalizing that all small cell nuclei in an area are non-neuronal is tough. Related note; splitting hairs again, but astrocytes "are the blood brain barrier" is not entirely accurate, in that endothelial cells actually form the blood brain barrier.
arachnoid mater is just a layer. the sub-arachnoid space is where all the vasculature is. between the arachnoid mater and the pia mater you will find the subarachnoid space. sorry you never got an answer to this Q for 2 years :(
@Eklipse113 'astrocytes surround the blood brain barrier' is how I would describe the situation; I said I was splitting hairs with that point. (I have a doctorate in neuroscience, specifically related to brain injury).
15 years after upload, this are still the best tutorials you can find on youtube and they save my a** often during first year of med school. Thanks for ur videos, not all heroes wear capes!!
You MADE my day!!!
This was uploaded when I was six years old, and now at 23 I'm using it to study for my first medical school exam. Crazy stuff, thank you so much Dr. Minarcik.
I freaked out when you said don't freak out, always a precursor for bad news.
Can you please do an update of this where you differentiate between the six layers of cerebral cortex please?
Нет
@darlantro Just to add a little more explanation... The blood brain barrier was discovered by Ehrlich who injected dye into the blood and noted it didn't reach the brain, later one of Ehrlich's students injected dye into the CSF and noted the dye didn't reach the blood. (Much) more recent repeats of this second experiment with microscopy show that the endothelium of blood vessels in the brain, not astrocytes are the barrier, as the dye in the CSF reaches the endothelium but not through it.
Dr. I’m here… a medical student from 2023
YaY
@radium86 This is correct: to be specific, endothelium is the blood brain barrier. The role astrocytes play in the BBB is their foot processes induce the cells of the endothelium to form the tight junctions that make up the BBB.
So if asked "what makes up the BBB", the answer is endothelium, but you should also be aware that astrocytes play a role in it as well, though it is indirect.
I hope no test question would have only endothelium as the answer. Endothelium is present in all vessels. The BBB is also made of astrocytes and pericytes. I wouldn't call it indirect
how do you differenciate the 6 layers?
Thanks ! This video is very useful to me but i still have the problem with the identification of other cell types in brain tissue like macrophage or PMN in the inflammatory response
A little correction, the meninx is the dura mater, not the arachnoid
One part of my histology-exam is a slide test, and if I pick Cerebral cortex I must distinguish the six cytoarchitectonic layers.. Do you have any tips on how I can tell the difference between them?
Посмотри в гугле
Cool video!
A lot of those small cells are endothelial cells forming vasculature... maybe worth pointing out that they are non-CNS but still in your slice. Also, there are smaller neuronal nuclei (for sure in layers 2,3 & 6of the cortex) so generalizing that all small cell nuclei in an area are non-neuronal is tough.
Related note; splitting hairs again, but astrocytes "are the blood brain barrier" is not entirely accurate, in that endothelial cells actually form the blood brain barrier.
Верно
arachnoid mater is just a layer. the sub-arachnoid space is where all the vasculature is. between the arachnoid mater and the pia mater you will find the subarachnoid space.
sorry you never got an answer to this Q for 2 years :(
agreed. it's kinda missleading that he speaks of "arachnoid mater" instead of "subarachnoid space" at 00:56.
or am I wrong?
Is this from the Iowa set on the biolucida program?
almost freaked out...
Theresa Stangl Why?
Dear sir please give some pointers to differentiate low grade glioma vs reactive gliosis
Thank you very much. :)
Sayonara!
Thank you Sensei, and sayonara😁
Is this a meningitis case?
No
@@WashingtonDeceit the arachnoid is infiltrated with WBC?
Brain have more than two types of cells
Thanks
@Eklipse113 'astrocytes surround the blood brain barrier' is how I would describe the situation; I said I was splitting hairs with that point. (I have a doctorate in neuroscience, specifically related to brain injury).
Ого, у вас есть доокторская степень ? И вы смотрите ролики на ютубе ?
why is it white around the blood vessel does it have to do with myelin?
heeheehee NeurAHn
this channel stole your video as their own if you want to file some sort of copyright infringment ua-cam.com/video/YZwu3CTJQtk/v-deo.html
I'm freakin' out my exams are in month
i love you