This is the best explanation about topical retinoids I have seen so far by a dermatologist on the internet. It seems at this point saying people should avoid all topical retinoids is superstition. I've been doing my own research - and by that I mean I have a scientific PhD and I have been reading all primary research articles -and there has only been some case studies claiming a link between birth defects and topical retinoids. Those articles literally have 1 patient and all of those studies had confounding factors. When you look at studies including a decent number of patients there is literally no difference whatsoever between those using topical retinods and those who do not. Also, it is questionable if topical retinoids even make it past the skin into the blood.
Could you give percentages of the ingredients (tolerance level). For example, what percentage of Vitamin C is safe for pregnancy? 20%? Same for Salicylic acid, AHA and lactic acid. I want to know the specific percentages so I can avoid harmful effects
Hi Dr. Liu! Is it okay to use chemical sunscreens while breastfeeding? I love Korean chemical sunscreens with the newer filters especially :). Thank you!
Thank you so much for shedding light on chemical vs physical sunscreens! Thank you so much for the in-depth video in general. It really cuts through the noise created by Google searches. I'm glad I've been a fan of your content so that I knew who I could turn to for insight.
Can someone explain why derms say azelaic acid is safe in pregnancy with such certainty, but when you look up the literature it says there isn't enough data to say so. This is from the FDA: There are no adequate and well-controlled studies of topically administered azelaic acid in pregnant women. The experience with FINACEA® Gel, 15%, when used by pregnant women is too limited to permit assessment of the safety of its use during pregnancy. Dermal embryofetal developmental toxicology studies have not been performed with azelaic acid, 15%, gel. Oral embryofetal developmental studies were conducted with azelaic acid in rats, rabbits, and cynomolgus monkeys. Azelaic acid was administered during the period of organogenesis in all three animal species. Embryotoxicity was observed in rats, rabbits, and monkeys at oral doses of azelaic acid that generated some maternal toxicity. Embryotoxicity was observed in rats given 2500 mg/kg/day (162 times the maximum recommended human dose based on body surface area), rabbits given 150 or 500 mg/kg/day (19 or 65 times the maximum recommended human dose based on body surface area) and cynomolgus monkeys given 500 mg/kg/day (65 times the maximum recommended human dose based on body surface area) azelaic acid. No teratogenic effects were observed in the oral embryofetal developmental studies conducted in rats, rabbits and cynomolgus monkeys. An oral peri- and post-natal developmental study was conducted in rats. Azelaic acid was administered from gestational day 15 through day 21 postpartum up to a dose level of 2500 mg/kg/day. Embryotoxicity was observed in rats at an oral dose that generated some maternal toxicity (2500 mg/kg/day; 162 times the maximum recommended human dose based on body surface area). In addition, slight disturbances in the post-natal development of fetuses was noted in rats at oral doses that generated some maternal toxicity (500 and 2500 mg/kg/day; 32 and 162 times the maximum recommended human dose based on body surface area). No effects on sexual maturation of the fetuses were noted in this study. Because animal reproduction studies are not always predictive of human response, this drug should be used only if clearly needed during pregnancy.
Hi there, I'm 8 weeks pregnant and i did not know that we are not supposed to use retinol during this time. I have been using olay 24 retinol night cream until now, but after scrolling over the internet about it, now I'm scared, please help.
Hi Dr. Liu. I’m currently 19 weeks pregnant and having severe acne. My doctor prescribed me Clindamycin. However, I’m just starting The Ordinary Azelaic Acid 10% and my doctor said i can continue using it. She didn’t explain further about how to use it together. How would you recommend using both of them? Thank you!
@@afifayasmeen1123 hi both! i do a lot of research and what I can tell by my personal (researched) knowledge is that, acne while being pregnant you can use following things: 1. A gycolic acid cleanser (Dermalogica one has a clean ingredients list.) 2. Sulphur (wash off mask) like the one by Sunday's Riley. 3. Azelic Acid 4. AHA's like Gycolic or Lactic Acid 5. Hydrocolloid patches (The big mighty pimple patch is pregnancy safe!) 6. Mineral sunscreen that is non-comedogenic like (Innisfree tone up no sebum sunscreen spf50) or Vanicream broad spectrum sunscreen spf50
Just an FYI for those of us with pre-eclampsia risks they start having us take a baby aspirin every day from 13weeks. So the salicylic acid topically is likely more than fine per absorption levels.
im not pregnant but i am an adult and i apply 2% salicylic acid liquid from neutrogena to half of my body, the lower half so legs, thighs, feat, buttocks etc. in order to treat ingrown hairs, but now that you mentioned poisoning and systematic absorption im actually a little bit scared to continue... it has helped me so much , i use it everyday and i dont get razor bumps anymore or ingrown hairs.. but i might have to stop because of your fear mongering :(
unless you have broken and inflamed skin barrier, its most likely fine. the the salicylate poisoning is theoretical but most expecting moms just don't want to take on
Hello Dr. Liu... I am not pregnant as of now but I have started to try to conceive. I have acne-prone skin and I have been using Paula's Choice 2% BHA exfoliant (in the morning) and also Salicylic acid spot treatments occasionally (at night) whenever I see any acne popping up. The spot treatments I use are Mario Badescu drying lotion and Clinique Anti-Blemish Solutions Clinical Clearing Gel. Can I continue using these? Also, I was considering using Inkey list salicylic acid cleanser too. If I continue using them all will it be too much Salicylic acid during this time or even after I get pregnant?
Hey! hi could you please look into the ingriends of the "cerave skin renewing nightly exfoliating treatment" and give your expert advice on whether or not it will be pregnancy safe? it has AHA's!
Hello, i have a question : the mauritia flexuosa fruit oli is it considered like vitamin A.? Is it allow to use this ingredient in a cream during the pregnancy? Thank you in advance ☺️
This is the best explanation about topical retinoids I have seen so far by a dermatologist on the internet. It seems at this point saying people should avoid all topical retinoids is superstition. I've been doing my own research - and by that I mean I have a scientific PhD and I have been reading all primary research articles -and there has only been some case studies claiming a link between birth defects and topical retinoids. Those articles literally have 1 patient and all of those studies had confounding factors. When you look at studies including a decent number of patients there is literally no difference whatsoever between those using topical retinods and those who do not. Also, it is questionable if topical retinoids even make it past the skin into the blood.
the thing is why would anyone want to put their baby at risk??? even if there is a 0.0001% chance, i would avoid it
Thank you this was SUPER helpful!
Do you recommend women trying to conceive or undergoing IVF should also avoid these ingredients or is it not necessary? Thank you
This video is the best and most precise video about this topic on UA-cam, thank you for sharing this information! ✨
The CeraVe skin renewing moisturizer contains encapsulated retinol. Is that a concern?
I looked it up and it doesn’t contain retinol, encapsulated or otherwise
Best skincare channel ❤
Could you give percentages of the ingredients (tolerance level). For example, what percentage of Vitamin C is safe for pregnancy? 20%? Same for Salicylic acid, AHA and lactic acid. I want to know the specific percentages so I can avoid harmful effects
It’s not really about the % as it is amount and frequency of use. Vit c and aha are safe period. BHA limit the amount and times applied to skin
What about Parabens, Phalates, Sulfates....rosemary,comfry, whichhazel.....
Is aloe Vera okay to use? I heard it helps with acne scares.
Does ordinary buffet and copper peptides are pregnancy safe or not
Hi Dr. Liu! Is it okay to use chemical sunscreens while breastfeeding? I love Korean chemical sunscreens with the newer filters especially :). Thank you!
Thank you so much for shedding light on chemical vs physical sunscreens! Thank you so much for the in-depth video in general. It really cuts through the noise created by Google searches. I'm glad I've been a fan of your content so that I knew who I could turn to for insight.
is allantoin safe for pregnancy?
Is niacinimide safe?
The cerave and cetaphil cleanser mentioned here is not available in the uk😢
Can someone explain why derms say azelaic acid is safe in pregnancy with such certainty, but when you look up the literature it says there isn't enough data to say so.
This is from the FDA:
There are no adequate and well-controlled studies of topically administered azelaic acid in pregnant
women. The experience with FINACEA® Gel, 15%, when used by pregnant women is too limited to
permit assessment of the safety of its use during pregnancy.
Dermal embryofetal developmental toxicology studies have not been performed with azelaic acid, 15%,
gel. Oral embryofetal developmental studies were conducted with azelaic acid in rats, rabbits, and
cynomolgus monkeys. Azelaic acid was administered during the period of organogenesis in all three
animal species. Embryotoxicity was observed in rats, rabbits, and monkeys at oral doses of azelaic acid
that generated some maternal toxicity. Embryotoxicity was observed in rats given 2500 mg/kg/day (162
times the maximum recommended human dose based on body surface area), rabbits given 150 or 500
mg/kg/day (19 or 65 times the maximum recommended human dose based on body surface area) and
cynomolgus monkeys given 500 mg/kg/day (65 times the maximum recommended human dose based on
body surface area) azelaic acid. No teratogenic effects were observed in the oral embryofetal
developmental studies conducted in rats, rabbits and cynomolgus monkeys.
An oral peri- and post-natal developmental study was conducted in rats. Azelaic acid was administered
from gestational day 15 through day 21 postpartum up to a dose level of 2500 mg/kg/day. Embryotoxicity
was observed in rats at an oral dose that generated some maternal toxicity (2500 mg/kg/day; 162 times the
maximum recommended human dose based on body surface area). In addition, slight disturbances in the
post-natal development of fetuses was noted in rats at oral doses that generated some maternal toxicity
(500 and 2500 mg/kg/day; 32 and 162 times the maximum recommended human dose based on body
surface area). No effects on sexual maturation of the fetuses were noted in this study.
Because animal reproduction studies are not always predictive of human response, this drug should be
used only if clearly needed during pregnancy.
Hello Doctor, is CeraVe the blue cleanser safe for pregnancy
Glyco A 5% soft peeling isispharma
Good or bad during pregnancy?
Hi there, I'm 8 weeks pregnant and i did not know that we are not supposed to use retinol during this time. I have been using olay 24 retinol night cream until now, but after scrolling over the internet about it, now I'm scared, please help.
Hi Dr. Liu. I’m currently 19 weeks pregnant and having severe acne. My doctor prescribed me Clindamycin. However, I’m just starting The Ordinary Azelaic Acid 10% and my doctor said i can continue using it. She didn’t explain further about how to use it together. How would you recommend using both of them? Thank you!
Hey are you still using Clindamycin and does it help you ?? I am also facing severe acne problem and i am 21 weeks pregnant
@@afifayasmeen1123 hi both! i do a lot of research and what I can tell by my personal (researched) knowledge is that, acne while being pregnant you can use following things:
1. A gycolic acid cleanser (Dermalogica one has a clean ingredients list.)
2. Sulphur (wash off mask) like the one by Sunday's Riley.
3. Azelic Acid
4. AHA's like Gycolic or Lactic Acid
5. Hydrocolloid patches (The big mighty pimple patch is pregnancy safe!)
6. Mineral sunscreen that is non-comedogenic like (Innisfree tone up no sebum sunscreen spf50) or Vanicream broad spectrum sunscreen spf50
Hi, I would love to know your thoughts on Goodal Green Tangerine Vitamin C Dark Spot Serum. Is it safe to use during pregnancy? Thank you.
Just an FYI for those of us with pre-eclampsia risks they start having us take a baby aspirin every day from 13weeks. So the salicylic acid topically is likely more than fine per absorption levels.
Yes you are right, but again, theoretical risk that most moms and providers just don't want to take on
Hi, I see that Cerave cream contains Phenoxyethanol, is this safe option during pregnacy?
Hello, Wanna know if it's safe to use Alpha Arbutin 2% face serum while pregnant?
No it's not safe
Can you use Aha and bha?
AHA is safe
Hi doctor, is sepi white powder, giga white powder and kojic acid dipalmitate safe during pregnancy?
Hi Dr. Liu. Are growth factors safe to use during pregnancy? I am currently using SkinMedica TNS Serum. Thanks in advance!
Great information!
Is the anti-blemish serum from skim ceuticals safe also during pregnancy???
It has sal acid, so unless you spot treat, don't recommend
im not pregnant but i am an adult and i apply 2% salicylic acid liquid from neutrogena to half of my body, the lower half so legs, thighs, feat, buttocks etc. in order to treat ingrown hairs, but now that you mentioned poisoning and systematic absorption im actually a little bit scared to continue... it has helped me so much , i use it everyday and i dont get razor bumps anymore or ingrown hairs.. but i might have to stop because of your fear mongering :(
unless you have broken and inflamed skin barrier, its most likely fine. the the salicylate poisoning is theoretical but most expecting moms just don't want to take on
Hello Dr. Liu... I am not pregnant as of now but I have started to try to conceive. I have acne-prone skin and I have been using Paula's Choice 2% BHA exfoliant (in the morning) and also Salicylic acid spot treatments occasionally (at night) whenever I see any acne popping up. The spot treatments I use are Mario Badescu drying lotion and Clinique Anti-Blemish Solutions Clinical Clearing Gel. Can I continue using these? Also, I was considering using Inkey list salicylic acid cleanser too. If I continue using them all will it be too much Salicylic acid during this time or even after I get pregnant?
Okay to use if not, and limit use of Sal acid when you are
@@dr.jennyliu So, do you recommend only when needed? Can I use the cleanser on daily basis though?
My wife’s skin was the best during pregnancy.
How did you end up watching this video ?
Wow. Terrible topic. Love to learn from you.
Wow. Terrific topic. So informative. So much to learn from you.
What about Parabens, Phalates, Sulfates....rosemary,comfry, whichhazel.....
Very informative. Thank you! Please consider doing one for breastfeeding!!
Will do! Pretty much can add back most topicals including retinoids, but still recommend avoiding hydroquinone
Hi Dr.. Can I use Kojie San for hyperpigmentation during pregnancy ?
thanks so much!! amazing video!!
Do you recommend paulas choice azilaic acid in pregnancy?? Plz respond 😢 because it had calicic acid in ingredients
Hi. Is sodium salicylate in Venus shaving gel Safe during pregnancy ?
Is allantoin safe for pregnant women?
Hey! hi could you please look into the ingriends of the "cerave skin renewing nightly exfoliating treatment" and give your expert advice on whether or not it will be pregnancy safe? it has AHA's!
Hello, i have a question : the mauritia flexuosa fruit oli is it considered like vitamin A.?
Is it allow to use this ingredient in a cream during the pregnancy?
Thank you in advance ☺️
How about Urea?