Blood biomarker for ASD: Validation Study - BRAIN Investigator Dwight German PhD

Diagnosing autism poses challenges due to its reliance on behavioral observation alone. Identifying specific biological markers could aid in the early detection of at-risk children, improving diagnosis and facilitating timely access to early interventions for better outcomes. Additionally, the diversity among patient groups complicates the development of therapeutics for autism, making it difficult to determine effective treatments for specific 'responsive' subgroups. Therefore, the development of objective biomarkers is crucial to predict therapeutic responses and categorize patients based on distinct biological subtypes.
The BRAIN Foundation is proud to support the largest proteomic study to date, aimed at validating blood biomarkers for autism. Led by Dwight German, Professor in the Department of Psychiatry at the University of Texas Southwestern Medical Center at Dallas, this project seeks to validate a blood biomarker panel for autism in a new cohort of ASD and typically developing boys using a comprehensive proteomic and machine learning approach. The study involves analyzing over 7000 proteins through multidisciplinary collaboration encompassing ASD diagnosis, biomarker development, and machine learning expertise.
This project was funded as part of The BRAIN Foundation 2023 funding round.
To find out more about the research we fund and how to apply visit brainfoundatio...
#biomarkers #diagnosis #earlyintervention #autismspectrumdisorder
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The BRAIN Foundation brainfoundatio... is a 501c(3) non-profit. The founders of BRAIN envision a world where every child and adult on the autism spectrum is healthy, participates fully in education and employment, and has a better quality of life. It aims to catalyze research that results in evidence-based interventions for the disabilities associated with autism, and also results in better medical standard of care.
To accomplish this, it funds impactful research through #philanthropy and our network of partners in the venture, corporate, and grassroots community.