Carbon Dioxide Transport
Вставка
- Опубліковано 13 кві 2014
- Brief introduction to carbon dioxide transport in the blood. Bicarbonate buffer system perspective.
Topics Discussed:
Bicarbonate buffer
Carbon Dioxide transport
Oxygen Transport
Chloride shift
carbonic anhydrase
red blood cell
co2
h2o
hemoglobin
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/ @anatomyondemand
literally the BEST explanation of what happens in the blood buffer system both chemically, mechanism, and biologically. Thank you!!!!
far better than any of my teachers have ever explained it thanks
One of the best lectures I've seen on the subject.
I saw a comment asking about where the CO2 in the blood comes from and where it goes, so I thought I'd comment in case anyone else watching wants to know. CO2 is a waste product of glucose metabolism in cells and it accumulates in the tissues. When oxygen carried by hemoglobin (in red blood cells in plasma of blood) passes thru the body, it gets ejected at places where the CO2 is accumulated. But the CO2 accumulation itself doesn't trigger the release of oxygen. The CO2 actually enters the blood plasma and from there it enters red blood cells where its broken down into carbonic acid and then further into protons (H+) and bicarbonate. The increase in this proton (H+) concentration is what triggers the hemoglobin to release the oxygen that it's holding, into the tissue. After delivering the oxygen to the tissues, the red blood cell takes up the CO2 and the blood flow continues to the heart from where it will enter the lungs to be exhaled.
Thanks for the UA-cam videos! You talk about science the way people talk about movie twists. You’re so excited and passionate! It helps me see just how incredible our body is, all the things that have to happen in order for us to function!
SO helpful! I was having trouble understanding this in lecture and from the textbook, but the way you explained it made it easy to grasp. Thanks!
I stumbled upon your explanation and it was by far the most concise yet informative and detailed.
Such a phenomenal explanation, the diagram was perfect and you simplified it all very easily. Thanks!
Thank you! thank you!
Really great explanation, far better than any other I have seen.
Clean, simple and makes sense.
Appreciate it very much!
Still can't believe you gave us so much information with only 1 picture, great work!
this was great! all of the other videos on this subject that I found on youtube can't match yours. this is the complete cycle from the tissue to the lungs, and no one else has talked about the whole cycle. thanks!
AndreaaaNS please do watch my video on transport of carbon dioxide ua-cam.com/video/Sc-g6Ogg-RI/v-deo.html
Your explanation of this process is great!
Thank you!!!
So well explained that even I as a non-native speaker could get it. Thank you!
While many videos explain the conversion of carbon dioxide in the red blood cell, this is the first I found that explains how the conversion is reversed in the alveoli. Thank you.
Great explanation thx really helped
This is very helpful. Thank you so much!
First semester nursing school student here. great video :)
In the uk we have to do this at 16/17, it’s so difficult! Good luck with nursing school :)
Excellent job explaining this! Thanks
This video made it seem so simple thank you for the help! Great explanation!
Thank you! Very simple yet informative
I have a feeling this topic is going to be the essay question on my final because my teacher talked a lot about this today. He made no sense at all. You explained this so well, thank you.
Thank you! This will help me with my final, you explained it easier than the book and my teacher combined.
this is the best way ive heard it explained! thank you
Thank you so much, very clear explaination. I now understand the chloride shift and carbon dioxide transport! Better explaination than my teacher
9 years later and it's still being used
Thank you so much very good explained and love your structure.👏🏻👏🏻👏🏻👏🏻
What beautiful way to explain this process, thank you so much!!
Great video! thank you so much!!
Thank you very much, it made carbon dioxide transport easier to understand.
Thanks for this video. I want to study Respiratory Therapy and this will help me a lot.
Just wonderful. Thank you
Perfect explanation. Really helpful.
Very spectacular Video, I really understand the entire mechanism, thanks a lot
Awesome video! This helped so much more than my teacher did in lecture!!
that was ultra clear and helpful, many thanks
Man that was sick!
Very nicely done! Thanks!
Amazing! Thank you so much, it finally makes sense
EXCELLENT VIDEO!
I had this diagram in my CIE endorsed textbook and it wasn't that easy to understand and thought wasn't making any sense. After I watched your video it made it easy for me to understand the concept.
spectacular explanation. Thank you
Thank you for this lecture man!
very good explanation! Please make more videos with pictures. You helped me a lot during studying! ❤️
Great video. Thank you!
Thank you! Great video! Totally understand this now! :)
Great video!
Thnku very much. The thumbnail itself suffice to know the mechanism. Thnks🙌🙌🙌love from india
Thank you so much. You’re such a blessing
Life saving video!! Thank you sir!!
This video basically saved my life 😅😅 ty tysm♥️♥️
Thank you so much! So helpful!
this was insanely helpful!! thank you sir
Can you comment on the difference between the hemoglobin buffer system vs the carbonic acid-bicarbonate buffer system?
This was very helpful, thank you.
Super helpful! Thanks so much!
Great explanation. Thank You
thankyou so much for this! i finally understood it after trying to get it for so long!! thank youu
this is fire flames thank you.
amazing explanation!
incredible explanation !!!
Why is deoxygenated Hb a better H+ buffer/proton acceptor than oxygenated Hb?
That was fantastic!!!!!!!!!
such a good explanation!
Great video bro!
Thank you so much for this!
thanks this was awesome
a very good and helpful video 100 percent. thank you so much
so so so helpful. thank you!
Great job bro , jst awesome explaination man 🤩🤩
awesome!
very helpful!
Thank you for the easy explanation, mademy med physiology exam a lot easier
Thank you so much!!
Is carbonic acid diffusion from the lymphatic system into the blood effective or does it happen at a fast rate? I saw somewhere where they said this happened very slowly.
Thank you so much! For some reason it wasn’t clicking until I watched your video.
Thanks a lot , you've saved me 🙏
it's 2 am and i have a bio exam tomorrow and i love you greg
sorry to be ask so this is mean that hemoglobin is not specificly bind the co2 but it actually made it to bind H+? so what does bind the HCO3 in RBC ?
thank you very nice, appreciated
really helpful..thanks sir
awesome
10\10
thnx for the additional informations❤
very good
Awesome
This was so helpful
Great👍👍👍👍
Thank you.
Awesome..thank you so muchhh
After we get the C02 from the working tissue cell, and its pulled into the RBC, where do we get the h2o from to turn it into carbonic acid? - do we just 'suck' it in from the high concentration of h2o in the blood plasma ?
Thanks for the video ! the rest made more sense then my text book !
Since the blood is a watery (aqueous) solution the water is always present and available for use in chemical reactions.
What i dont Understand: Chlorid is Negative and hco3 as well so why do i have to Change?
I don't think he mentioned this in the video but NaCl is present in the plasma as this reaction takes place. So HCO3 is forced out of the RBC into the plasma and attaches to Na (from the NaCl compound) resulting in NaHCO3. The Cl (from the NaCl compound) then enters the RBC to maintain electric neutrality. Thats why this process is called the chloride shift because Cl is shifting back and forth from the plasma to the RBC.
Hope that helps! :)
Electric balance would have been the same if HCO3 stayed in the RBC and Cl in NaCl. Why exchange?
gr8 video..
Btw where is the pict you got? Reference plis
Excelent video, can you point out some references abou the rates, duration and energy costs of these processes?
+Jonathan Ron My favorite reference for human physiology is "Textbook of Medical Physiology" by Guyton & Hall. Also, CVphysiology.com is a great online resource.
Specifically what rates and durations are you interested in?
Thanks,
I'm trying to estimate a general limit time for apnea. so I'm interested in the reaction rates ( how long) and the rate of increase of CO2 levels in the blood and lungs
CVphysiology is indeed a gem. You've provided a well-paced and lucid video as well. Good job.
So carbonic anhydrase has 2 roles? It catalyses the breakdown of h2co3 and also formation of it?
yes
well !! but i have a doubt - what happens if bicarbonate is accumulated in RBC???????????????? is it burst??????
so CO2 is transport from where to where ?
Well put! It was a little unclear for me before this.
U r excellent
thanks very nice vedio
Thanks