DeepMind's AI Solves Protein Folding in Major Scientific Breakthrough

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  • Опубліковано 30 лис 2020
  • DeepMind's Alphafold 2 algorithm solves 50-year-old challenge
    Discord: / discord
    source:
    deepmind.com/blog/article/alp...
    www.technologyreview.com/2020...
  • Наука та технологія

КОМЕНТАРІ • 718

  • @matthewdunstone4431
    @matthewdunstone4431 3 роки тому +160

    Love this no spin, no hype format. Articulate, simple delivery. I have subscribed.

  • @AlanW
    @AlanW 3 роки тому +138

    Took a chance watching this from the recommendations, am not disappointed.

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +4

      :)

    • @esbuenodun
      @esbuenodun 3 роки тому +2

      I too am here on a recomendation. Glad I clicked... and subbed.

    • @Meleeman011
      @Meleeman011 3 роки тому

      I don't see why it's significant or why it took so long

  • @davids3905
    @davids3905 3 роки тому +15

    Thank you for not asking for a like, comment, and sub. Here is a comment for the UA-cam algos

  • @Acherus29A
    @Acherus29A 3 роки тому +74

    This is mind-bogglingly huge.

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +4

      ‼️‼️‼️

    • @simonci5177
      @simonci5177 3 роки тому +4

      @@DisruptionTheory So AI could design airborn virus that could kill all humans? Welcome to Skynet domination

  • @mikemuragemi6
    @mikemuragemi6 3 роки тому +101

    commenting so you score higher in the youtube algorithm

  • @hiradsamadi1686
    @hiradsamadi1686 3 роки тому +63

    So exciting to see how much sooner than predicted these breakthroughs are happening

  • @SacGeoTV
    @SacGeoTV 3 роки тому +8

    This was the ‘un-achievable’ holy
    grail of molecular nanotechnology
    back in 1993, according to K. Eric
    Drexler, Marvin Minsky et al ...
    ... or at least it was when we
    all shared a Chinese meal at MIT )

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому

      I have Drexler’s Engines of Creation but yet to read it to be honest... did you say you actually met him along with Minsky?!

    • @SacGeoTV
      @SacGeoTV 3 роки тому +2

      @@DisruptionTheory back in ‘93 I threw myself into nanotech after ‘engines’, I was well-connected in Boston, and networked with Drexler and his wife - dominated the alt-nanotech newsgroups... those were the days... then, by 1996/7 I found the rabbit hole ... SCI-Fi-level of Air Force / DARPA compartmentalizations and an eye-to-eye encounter w/ an Air Force / SSP / SDI spook (think “men in black” in an Air Force uniform)... I realized I hit the black-budget firewall... and wasn’t invited.

    • @SacGeoTV
      @SacGeoTV 3 роки тому +3

      @@DisruptionTheory programmable protein folding unleashes EVERYTHING ... Pandora ..
      Prometheus... Singularity.... and makes CRISPRs and mini-nukes look like LEGOs

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому

      @@SacGeoTV sounds fascinating. We should connect on discord (link in description) would love to hear more

  • @noiamhippyman
    @noiamhippyman 3 роки тому +15

    This stuff is way over my head but I’m happy for people who do understand it!

  • @AlphonseJames-FxWorth
    @AlphonseJames-FxWorth 3 роки тому +10

    Sometimes I feel as if I was born early...
    I dont feel that way anymore now

  • @SpikeTFA
    @SpikeTFA 3 роки тому +9

    I genuinely thought something like this wasn't going to be feasible until quantum computation was more mainstream. The fact that they can run these algorithms now on current tech just makes me salivate for what's coming, and soon... for real, people aren't ready for what's coming and how much things with change, even in the next 5 years. What a time to be alive

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +2

      Same actually, I always assumed there’s a certain limit on the current hardware paradigm, no matter how much raw computational power we throw at it. I can only imagine what Quantum + AI will usher into existence..

    • @SpikeTFA
      @SpikeTFA 3 роки тому +1

      @@DisruptionTheory well, one thing I've noticed over maybe the last couple years is way fewer people jumping on the "lol Kurzweil is a dumbass" train

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +2

      Lol true true. He’s either gonna go down in history as a prophet or a nut

  • @paulneilson6117
    @paulneilson6117 3 роки тому +12

    I quit cell biology years ago when I realized AI could do it more easily. Guess what, hehe.
    Yes, it is hard to overstate this amazing advancement.
    Terraforming is the ultimate goal.

  • @JennWatson
    @JennWatson 3 роки тому +2

    Glad this was recommended- this news is exciting!
    I’m gonna binge on your channel now, thanks!
    😊

  • @torino429scj
    @torino429scj 3 роки тому +1

    Clear, concise report on this monumental accomplishment. Amazing developments are on the horizon and it's a pleasure to be alive at this time to see things like this unfold.

  • @timw1971
    @timw1971 3 роки тому +1

    Great video! Love the laid-back style. Very clearly explained.

  • @chrisminnoy3637
    @chrisminnoy3637 3 роки тому +1

    BOINC also has these projects for folding proteins: Rosetta and GPU Grid. AI and distributed computing are really the technologies that will bring the next steps in science. That's why we (Cnergy) as a young start-up are building databoilers, that will bring distributed computing and AI to your home in an environmentally and cheap way.

  • @janice3691
    @janice3691 3 роки тому +1

    Fantastic delivery! Subscribed.

  • @orensomething
    @orensomething 3 роки тому +1

    Great coverage man, subbed. Thanks.

  • @arkanedesigns
    @arkanedesigns 3 роки тому +1

    Great video, straight forward and informative!

  • @caseyalbright2762
    @caseyalbright2762 3 роки тому +1

    Just subscribed . Love your delivery bro. All info no bull.

  • @clavo3352
    @clavo3352 3 роки тому +1

    Holy Cow! First time I subscribe on initial viewing! Fantastic video! TY.

  • @sirousmohseni4
    @sirousmohseni4 3 роки тому +1

    Excellent report.
    Thanks

  • @younanm
    @younanm 3 роки тому +3

    This ranks in the top 5 important problems solved since the begining of time! now we should deconstruct how it came to the solution

  • @william_8844
    @william_8844 3 роки тому +10

    Best explanation of the breakthrough I have seen this far

  • @drpepiman
    @drpepiman 3 роки тому +1

    Very well put together content my guy, I subscribed

  • @rifleman42051
    @rifleman42051 3 роки тому +5

    Love the content! Subbed!!!

  • @henriquejorge4280
    @henriquejorge4280 3 роки тому

    Thank you for the science and the love you shared!

  • @SoldierMHGod
    @SoldierMHGod 3 роки тому +1

    Pretty straight forward. Kudos bro no time wasting. Two thumbs.

  • @DoctorJack16
    @DoctorJack16 3 роки тому +3

    Glad I stumbled across your channel. You hit on exactly what I was hinting at in my Covid vaccine video. The future will come at us exponentially due to the advent of AI. It will be hard for our psyche to wrap our minds around it now and in the future. Great video. Liked and subscribed!

  • @Julian-tf8nj
    @Julian-tf8nj 3 роки тому +4

    On the scale of the invention of penicillin, of the first heart transplant, etc. A defining moment in the history of Medicine!

  • @fast_harmonic_psychedelic
    @fast_harmonic_psychedelic 3 роки тому +31

    We're at the cusp of the golden age, but the true golden age still lies ahead. March onwards towards the shining future.

    • @DavidKnowles0
      @DavidKnowles0 3 роки тому +4

      most of us in our thirties might see this gold age!

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +6

      I'm a firm believer that we will. And I'm not the most optimistic person

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +2

      Beautifully said

    • @sebione3576
      @sebione3576 3 роки тому +1

      Boilers and toilets. Toilets and Boilers. T'aint a boiler nor a toilet.

    • @stevejordan7275
      @stevejordan7275 3 роки тому +1

      That depends very critically upon *who gets it.* Shall we put this AI at the disposal of Vladimir Putin? Of Donald Trump? Martin Shkreli? Xi Jinping? Gurbanguly Berdymukhammedov?

  • @pwells2389
    @pwells2389 3 роки тому +3

    Cool news! Thanks for popping into my suggestions. Subscribed. Be interested to hear more specifics on how this helps.

  • @globelthreatx
    @globelthreatx 3 роки тому +1

    First I need to address how much I appreciate discovering a UA-cam Channel where you don't need an obnoxious 30second animated intro, and spend 20 minutes struggling to summarize your thoughts while going off on irrelevant tangents. You are very well spoken, articulate, informative and easy to follow, all summarized in a 5 minute video! You deserve way more Subs!

  • @xEchoEaglex
    @xEchoEaglex 3 роки тому +1

    Good stuff, more please. Thank you.

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому

      Thanks, turn on the bell notification to know when new videos drop !

  • @brenton2561
    @brenton2561 3 роки тому +1

    Nice channel.
    You got a new sub keep up the good work, mate.

  • @mackblack5153
    @mackblack5153 3 роки тому +1

    Very informative. Thanks a lot!

  • @hopper2716
    @hopper2716 3 роки тому +5

    Nice coverage.. you are one of few that do not have an annoying voice... hope you will do more frequent video's... especially about future stuff -- for now, welcome into my tiny bubble :-)

  • @arincrumley
    @arincrumley 3 роки тому +5

    Great job sharing this awesome news!

  • @davordebrecin2054
    @davordebrecin2054 3 роки тому +1

    Great video, subscribed!

  • @evanstevens8021
    @evanstevens8021 3 роки тому +1

    Wow this is fascinating! Also man you have a wonderful speaking voice, thanks for relaying this news brotha

  • @kolawoleoluwasegun5883
    @kolawoleoluwasegun5883 3 роки тому +1

    Refreshing in multiple ways and informative.

  • @Teklectic
    @Teklectic 3 роки тому +1

    This is an amazing breakthrough!

  • @negvey
    @negvey 3 роки тому +1

    nice quick fast explanation!

  • @esbuenodun
    @esbuenodun 3 роки тому +6

    A protein that consumes plastic and creates O2

    • @ik1408
      @ik1408 3 роки тому +1

      Consumes greenhouse gases. You would not want tye growth of oxygen in the atmosphere. At one point the air would have become combustible.

  • @n-i-n-o
    @n-i-n-o 3 роки тому +2

    Great commentary thx

  • @thm4643
    @thm4643 3 роки тому +1

    Many Thanks for the news of this discovery!

  • @Johnobomb
    @Johnobomb 3 роки тому +1

    Great video, thank you for the informative content.

  • @diegosolis8272
    @diegosolis8272 3 роки тому +1

    Amazing channel ! you have 1M potential for sure!!!

  • @kevingeorge862
    @kevingeorge862 3 роки тому +1

    Clear. Articulate. On point. Thanks

  • @kylesampson4016
    @kylesampson4016 3 роки тому +1

    I have to say, finding you on UA-cam is finding pure gold, I'm very impressed, I want to produce videos like yours

  • @tafry79
    @tafry79 3 роки тому +5

    "Nobel Peace prize in Chemistry" WTF???

  • @rexblueskyes2450
    @rexblueskyes2450 3 роки тому +1

    exciting to discover your channel

  • @dooshmasta
    @dooshmasta 3 роки тому +12

    The speed at which the future is coming toward us is accelerating

    • @haralbi
      @haralbi 3 роки тому +2

      If the future is coming toward us it means time machine "has been" invented in the future.

    • @AtlantaTerry
      @AtlantaTerry 3 роки тому

      Some say the future already exists.

    • @nschulz5698
      @nschulz5698 3 роки тому +2

      yes, even Alvin Toffler would be shocked

    • @dooshmasta
      @dooshmasta 3 роки тому

      @@nschulz5698 RIP

  • @NeoRetroX
    @NeoRetroX 3 роки тому +3

    This could help solving prion disease and altering life forms as we know them. Adjusting our own proteins to improve our tissues, metabolic processes etc. incredibly cool stuff!

  • @nguvercin
    @nguvercin 3 роки тому +1

    Fascinating discovery and thank you for the perfect explanation.

  • @EthanLR
    @EthanLR 3 роки тому +1

    Great stuff!

  • @bary1234
    @bary1234 3 роки тому +1

    Subbed. Cool content.
    Greetings from Finland :)

  • @JJs_playground
    @JJs_playground 3 роки тому +1

    Thank you for doing this video. Because I was trying to understand what all the hype was about. Now I understand it a bit more

  • @wimveninga1714
    @wimveninga1714 3 роки тому +1

    Thank you for your clear and concise storytelling.

  • @RR-fs9wl
    @RR-fs9wl 3 роки тому +2

    quality vid man, keep it up!

  • @HMatheusSLima
    @HMatheusSLima 3 роки тому +2

    I've liked your explanation about the implications of this technology, it's very didactic, thank you.

  • @NandishPatelV
    @NandishPatelV 3 роки тому +2

    For a non biologist like me with some understanding of AI, your account was of protein folding problem was easy to understand. Thanks :))

  • @kamilwhite8139
    @kamilwhite8139 3 роки тому +1

    Great explanation

  • @crystalyzzed
    @crystalyzzed 3 роки тому +2

    Great content!

  • @Todd66
    @Todd66 3 роки тому +1

    Well done on the video.

  • @bkrharold
    @bkrharold 3 роки тому +1

    This is a tremendous accomplishment of historic proportions. The recent progress in biological and materials sciences is astonishing. It will make it possible for tremendous positive changes, solving urgent problems for humanity, the health and sustainability of our planet and all her life forms.

  • @Xalgucennia
    @Xalgucennia 3 роки тому +33

    To be honest, with enough computing power, this was just a matter of time and refinement.
    Thanks gamers for pouring billions into the gpu industry and making processing power dirt cheap!

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +12

      Agree but it’s a bit unfair to frame it as pure computing problem. Algorithms play an enormous role

    • @longboardfella5306
      @longboardfella5306 3 роки тому +11

      The game of Go and protein folding are not readily solved by brute force. You do need massive compute power to run most advanced Ai models BUT it is not enough. The algorithms and the feedback learning loops are the real breakthroughs and the developers shod be recognised for their insights to make it possible

    • @raspberrypi4970
      @raspberrypi4970 3 роки тому

      Processing power is now defined by # of qubits.
      Like Dwave Advantage...5000Qubits
      So far the most powerful Quantum computer

    • @ghfhgfuuu
      @ghfhgfuuu 3 роки тому

      You're welcome

  • @libra8993
    @libra8993 3 роки тому +1

    this is the most exciting and promising news ive heard in decades! AMAZING.

  • @dinkledankle
    @dinkledankle 3 роки тому +1

    I never expected it to be solved so soon. I've known about the protein folding problem for over a decade now and it has always interested me. When they developed CRISPR-Cas9 I was super excited because of what it is capable of, but now that they've solved protein folding as well... man, I can't wait to see what they do with it. _So_ many possibilities. Like telomeres that don't degrade 😃

  • @bobbromley1629
    @bobbromley1629 3 роки тому +1

    Excellent content

  • @Access.Denied
    @Access.Denied 3 роки тому +1

    More AI stuff dude! I'm a sucker for those! Great video.

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +1

      Thanks, chuck the bell to receive notifications. I got a crazy vid coming

    • @Access.Denied
      @Access.Denied 3 роки тому

      @@DisruptionTheory done and done! 👌

  • @pixel7038
    @pixel7038 3 роки тому +15

    Leaving comment for UA-cam algorithm

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +1

      Preciate you!

    • @AroundnBackAgain
      @AroundnBackAgain 3 роки тому +1

      Gaming the algorithm is a slippery slope... of the trend catches on, it will have significant unintended consequences that would be for the better to avoid.

  • @ramade9040
    @ramade9040 3 роки тому +1

    Your camera position is slightly awkward but the content was gold 🥇

  • @ConnoisseurOfExistence
    @ConnoisseurOfExistence 3 роки тому +5

    Great video! I already shared Deepmind's own video on the last achievements of Alphafold, but I'm sharing this one too. Yeah, the rate of discoveries is accelerating. Maybe we're already into the technological singularity...

    • @mikemuragemi6
      @mikemuragemi6 3 роки тому +1

      The singularity is way far off in the distant future, i think

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +1

      Appreciate it! Where are you sharing btw?

    • @ConnoisseurOfExistence
      @ConnoisseurOfExistence 3 роки тому +1

      @@DisruptionTheory Facebook, on my profile and 2-3 futuristic groups.

    • @ConnoisseurOfExistence
      @ConnoisseurOfExistence 3 роки тому +1

      @@mikemuragemi6 There's no human, who can keep up with all scientific breakthroughs happening all the time. And many of them are due to AI. I think the singularity is right now, or very soon...

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому

      You should join the discord group, which groups ?

  • @HunterMcNew
    @HunterMcNew 3 роки тому +1

    Good video interesting content. Subscribed 😁

  • @UghIHateTheseThings
    @UghIHateTheseThings 3 роки тому +11

    I downloaded the fold at home program as well. I figured it was going to be our trump card for at least the next decade. AI surpasses all expectations once again.

    • @samsungtelevision695
      @samsungtelevision695 3 роки тому

      @Mister Meeseeks I’m no AI but I see tank man and 1989 so probably.

  • @thejohnringo
    @thejohnringo 3 роки тому +1

    Great report! I wonder if AI will also make advances in protein-substrate binding behavior,
    maybe predicting protein motifs with a high (the highest possible?) affinity for a particular substrate (e.g., DNA sequence) and,
    conversely, what substrates (e.g., a small, inhibiting molecule) would have high affinity for particular amino-acid sequences.

  • @Preludetoadream1
    @Preludetoadream1 3 роки тому +2

    Brilliant!

  • @MichaelWilliams-rf2jw
    @MichaelWilliams-rf2jw 3 роки тому +1

    Truly awesome.

  • @ldIezz
    @ldIezz 3 роки тому +15

    AI is humanitys last invention

  • @Layniebird1776
    @Layniebird1776 3 роки тому +1

    Awesome!

  • @erickrcisneros
    @erickrcisneros 3 роки тому +1

    Fascinating

  • @ronagoodwell2709
    @ronagoodwell2709 3 роки тому +1

    AI is a force multiplier for virtually every field it touches. Not only does machine intelligence move ahead to the next level, but it carries other research along with it. In this case: AI plus biology, medicine etc.

  • @curiousandcreativewithwand8515
    @curiousandcreativewithwand8515 3 роки тому +1

    Sweet!!!!
    Science on!!!

  • @stevenchen1345
    @stevenchen1345 3 роки тому +13

    The law of accelerating returns at work, beating all analyst predictions. Great work DeepMind!!

  • @MrKashes
    @MrKashes 3 роки тому +2

    deep mind will solve the old age issue as well and we will be bk to living 10,000 years again :)

    • @Jadty
      @Jadty 3 роки тому

      Again?

  • @BitcoinmeetupsOrg123
    @BitcoinmeetupsOrg123 3 роки тому +1

    Excellent

  • @EdeYOlorDSZs
    @EdeYOlorDSZs 3 роки тому +1

    Geometric deep learning is booming within AI, writing my thesis on it right now

  • @tentative_flora2690
    @tentative_flora2690 3 роки тому

    Honestly. Having tried to build a novel protein myself. This is a game changer. I hope they open source it for public use. People in the DIY bio community will be thrilled.

  • @negvey
    @negvey 3 роки тому +1

    the future looks more scary than ever, imagine somehow making a drug or some shit out of this technology and making a human suffer in a special chamber where they are essentially immortal, everyone can die now it is inevitable, but imagine not being able to die in a prison of endless suffering, there is a good reason why this universe has a great filter installed

  • @buggfire
    @buggfire 3 роки тому +10

    I feel like we'll make type I civilization by centuries end. Thanks to the inevitable AI.

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +2

      Hoping you’re right

    • @KaiHenningsen
      @KaiHenningsen 3 роки тому +5

      @@gmhero24 If AI doesn't turn out to be the (or a) great filter.

  • @emceeboogieboots1608
    @emceeboogieboots1608 3 роки тому +1

    Well that was interesting. I as no idea of the significance of protein folding until reading about CWD recently and it looks like I need to delve deeper.
    And check out some more of your videos...

  • @JBittermusic
    @JBittermusic 3 роки тому +2

    in 20 years humans will be out of this world, maybe inmortality? this is insane

  • @stea2494
    @stea2494 3 роки тому +2

    AI will be a blessing for resolving complex problems.

  • @ericblenner-hassett3945
    @ericblenner-hassett3945 3 роки тому +1

    The ' experts ' predicted we were " 10 years before electric cars are viable " while Tesla was rolling its' first 100 cars out of a factory. Don't trust experts to estimste when things happen without thinking of original series Star Trek and Scottie saying " it'll take hours to repair " while they were in combat.

    • @DisruptionTheory
      @DisruptionTheory  3 роки тому +1

      So even if experts predict when a technology will arrive, they can’t predict market forces or historic events that may delay it. Electric cars were technically viable 30 years ago but it took the market until recently to bring him into existence

  • @solosailorsv8065
    @solosailorsv8065 3 роки тому +2

    I was trying to explain this last week. Yes, protien folding could be huge for AI and Quantum computing( Qbits model biochemistry's quantum nature, better than binary) Deep Mind's self learning would be most likely if sufficient Learning Database was available. AWESOMENESS !! Medicine could LEAP forward !

    • @solosailor222
      @solosailor222 3 роки тому +1

      @Norm T Good point. It seems to me that custom gene therapies and even DNA repair (CRISPR) can be now done on specific individuals for specific cases. Such custom gene therapy would require a team of top experts and a multimillion dollar facility. But when a person is a multi millionaire on their deathbed, money is no object. Just keep it all VERY quiet and the research will be funded...

  • @MemesnShet
    @MemesnShet 3 роки тому +1

    This is incredible
    I can't wait till we can use an advanced version of that plain text to code translator
    That's gonna be sick

  • @bijanshadnia3620
    @bijanshadnia3620 3 роки тому +2

    Thanks

  • @pardal_bs
    @pardal_bs 3 роки тому +2

    Great news!

  • @jazzdirt
    @jazzdirt 3 роки тому +2

    We were all waiting for the next "Einstein" ... then we made one... LOL
    You did your intro=bit.. I was like:"They did what now?!??!" (in my defense it was autoplay.. I didn't read the title.. ) Wasn't expecting that... Wow..

  • @joseromantan
    @joseromantan 3 роки тому +1

    one baby step for skynet.