I am a second year med student reviewing this for boards (70k/year debt, woo!). I spent many hours attempting to learn this in my first year, but I never truly understood it beyond "free nitrogen is bad, urea is good... now memorize all these random chemicals to make urea...". I literally wasted hours of my life memorizing/purging this for exams, and now, in 13 minutes, you actually TAUGHT it to me such that I UNDERSTAND what the heck is going on. You have an incredible gift... Please never stop teaching. Thank you so much for this! Best of luck with your future endeavors.
You never cease to amaze me. Countless hours of studying cut to min. because you are a pro at organizing information and conveying it. THANK YOU! The few thumbs downs are probably from jealous profs. You kick ass.
Hey, I told all my friends about you! And even now when I'm no longer studying biochemistry but focusing on Internal Medicine I'm still getting back to you to remember the basics. So thank you so much. I will never forget your help. 😭♥️
Bro I am pharmacy student and believe me you are the reason i cleared my all the semesters and i can stand confident in front of my lecturer that even wirhout listening to there lectures i can clear the exam.. thank u very muchh..
I had biochemistry structure final exam today and I hadn't studied anything because I was so sick! So I woke up very early in the morning and started watching your lectures that were related to my exam! I'm just going to say that you are amazing because not only I'm going to pass but I also was able to answer some tricky questions because of the details you mention in your lectures! Thank you very much, god bless you!
thank you so much sir !! I was studying this from Lippincott but everything was just passing over my head. now after listening to your lecture everything is crystal clear! you provide every detail necessary for tests and your illustrations are also so perfect.
Thank you SO much for all your hard work and putting together this videos! You've helped me pass all my biochemistry classes in the University. You are so good at explaining everything. Love that everything is visual and color coded. You are amazing!!!!!!!!!!!!!
I would just like to let you know that you are a saint. One day when I have money I will be donating because you have saved me from failing my biochem courses. You deserve the world
Amazing I should really show your videos to my lecturer so he would learn how to teach better, I went to a 2 hour lecture today and didn’t learn anything, great work!
Shout out to my guy AK Lectures, man jeez! My biochem professor is good, but I never have time to go to her office hours with work and everything. This dude is literally my personal TA.
Sir, your lactures are full of important information and very much interesting and beneficial for us. I believe you are one of the best biochemistry teacher. Thank you Sir for such help 🙏🙏
Thank you so much! You have helped me many times in my biochemistry exam! Actually, you helped me aced it. Thank you for organizing a comprehensive summary of topics like this one.
There is one minor issue: inorganic pyrophosphate is quite stable at neutral pH and requires action of inorganic pyrophosphatase to convert it to two phosphates. Which is what happens. Without the action of inorganic pyrophosphatase, PPi would accumulate and inhibit many nucleotidyl transfer reactions, including those in nucleic acid synthesis. So 3 ATPs is what you need on the left-hand side of the urea cycle equation, not 4.
Quick question on the net rxn. I get that CO2 is converted to HCO3- using 1H2O but shouldn't the net rxn show the free H+ on the product side that disassociates from carbonic acid to form HCO3- or is it used somewhere and I haven't counted right?
Just a very minor issue - it would have been nice, if you had included the regeneration of aspartate by the reaction of oxaloacetate (formed in the CAC from fumarate) with another a-aminoacid, forming aspartate and a a-ketoacid! Anyway, thanks for your incredibly helpful lectures - they're amazing!
@3.30 you said that the fumarate is the bridge between urea cycle and gluconeogenesis. Don't you mean the bridge between urea cycle and citric acid cycle? (Krebs bicycle?)
I am a second year med student reviewing this for boards (70k/year debt, woo!). I spent many hours attempting to learn this in my first year, but I never truly understood it beyond "free nitrogen is bad, urea is good... now memorize all these random chemicals to make urea...". I literally wasted hours of my life memorizing/purging this for exams, and now, in 13 minutes, you actually TAUGHT it to me such that I UNDERSTAND what the heck is going on. You have an incredible gift... Please never stop teaching. Thank you so much for this! Best of luck with your future endeavors.
Can you tell me why you can summarize this for free + 100x better than my med school professors who I pay 50k per year?
right?!... this guy is the reason i might do alright on my boards lol
they give u a certificate
he explains this better 47932875982x better than my undergrad professors too 😂
Can't agree more bro
Every time I watch his videos have the same question as yours🤦🏻♀️ I’m really curious but however the reason I am always thankful for him
You never cease to amaze me. Countless hours of studying cut to min. because you are a pro at organizing information and conveying it. THANK YOU! The few thumbs downs are probably from jealous profs. You kick ass.
probably from jealous professors :,)))) lmao
man you are really an amazing lecturer, half of my good grades are because of your lectures. thank you for putting all these up.
seriously who would ever unlike this video !! U R world's greatest lecturer
thank u so much !
I wish i have money to give to this guy
Christian Mark Gerard Tuvera don't worry he's getting paid
Hannah Lopez I am actually not getting paid
@@AKLECTURES thanks a lot then!!
Same. Let me graduate and make a living. then for sure :)
@@AKLECTURES Omg, Incredible, you are amazing!
Hey, I told all my friends about you! And even now when I'm no longer studying biochemistry but focusing on Internal Medicine I'm still getting back to you to remember the basics. So thank you so much. I will never forget your help. 😭♥️
How did he get the urea cycle drawn in a perfect circle diagram? he is too good.
Aubrey Cabral using a compass...
@@faisalal-sammarraie9140 Did not use a compass.
@@AKLECTURES cool omg
A marker and a string?
there can never be an easier way to learn after watching ur lectures.
Bro I am pharmacy student and believe me you are the reason i cleared my all the semesters and i can stand confident in front of my lecturer that even wirhout listening to there lectures i can clear the exam.. thank u very muchh..
I had biochemistry structure final exam today and I hadn't studied anything because I was so sick! So I woke up very early in the morning and started watching your lectures that were related to my exam! I'm just going to say that you are amazing because not only I'm going to pass but I also was able to answer some tricky questions because of the details you mention in your lectures! Thank you very much, god bless you!
I have a big test tomorrow and I am so thankful I found your videos! They are the best tool EVER!! please keep up the good work!!!
Thank god for your brilliantly condensed and fastidiously distilled videos. I'm illuminated.
thank you so much sir !! I was studying this from Lippincott but everything was just passing over my head. now after listening to your lecture everything is crystal clear! you provide every detail necessary for tests and your illustrations are also so perfect.
Thank you SO much for all your hard work and putting together this videos! You've helped me pass all my biochemistry classes in the University. You are so good at explaining everything. Love that everything is visual and color coded. You are amazing!!!!!!!!!!!!!
Taking my Biochemistry exams tomorrow: if all goes well. After God, all the credits goes to you.
Abdimutaal Miyir Thanks to God who created him
Watching this video a day before exam..totally life saver! Thanks Sir! 🙏
the best lecture UA-camr ever
learnt more in these 13 minutes for free than 2 hours in a lecture for thousands a semester..... THANK YOU FOR THIS!
Trully gifted. Few understand this material in such depth and even fewer are able to explain it properly. Keep up the great work!
literally no one can explain this way better than you do🙌🙌🙌
I liked it when you spoke loudly in the mic and had a cool accent. This is too peaceful, bring the 2017 voice back
I love this person's teaching like anything
Respected Sir!
I just wanna say that you're great 💥🙏🏻
He really give us all the knowledge he has acquired for god knows how long for free.
I would just like to let you know that you are a saint. One day when I have money I will be donating because you have saved me from failing my biochem courses. You deserve the world
you are my hero! thank you for helping me through med school
Doctor, you’re so good in how to artistically put things together. Well wishes and many thanks.
I can't help commenting this on every video I watch on this channel ..... THANK YOUUUU!!!!!! :)))))
Ohh my god! You're just amazing. I was looking for this so long and finally found this video. Man! you made it CRYSTAL CLEARED!
I’ve never seen a better explanation. Thank u
U r great 😃 أنا فى كلية العلوم من مصر
اشكرك على الشرح الجميل
ههههه
رائع لست الوحيد الذي يتابعه
أنا ايضا من الجزائر
You got me through my biochem exam. Thank you so much. You are godsend
You are an excellent illustrator sir. Thank you for your amazing work.
Thank you sir.
Ur explanation is awesome
Your videos are great! They have been of great help to me. It makes understanding and learning so convenient.
Thank you so much for making these videos, you are getting me through my biomed degree!! So grateful
you are the best teacher ever !!!!! thank you so much
Amazing I should really show your videos to my lecturer so he would learn how to teach better, I went to a 2 hour lecture today and didn’t learn anything, great work!
Shout out to my guy AK Lectures, man jeez! My biochem professor is good, but I never have time to go to her office hours with work and everything. This dude is literally my personal TA.
always grateful for your videos! thank you
thanks for the kind words!
Sir, your lactures are full of important information and very much interesting and beneficial for us. I believe you are one of the best biochemistry teacher. Thank you Sir for such help 🙏🙏
Best video ever for protein metabolism... Long life❤❤❤
I JUST CAN'T THANK YOU ENOUGH
Hi babe
I'm getting ready for my biology Olympiad and this video did it all
thanks ❤
This is the best channel I have ever visited. Loved your explanation. Very very helpful.. Huge thanks from India sir :)
I just found your videos, and I am so glad I did! Very well explained and presented - thank you SO much!
Very clearly and succinctly explained! Thank you! My prof is nearly incomprehensible so this really helped me understand.
Your videos are amazing! I'm definitely donating. It's worth the $$. Thank you!
Very amazing, very talented man, you are better than our Biochemistry lecturers
انا من مصر😃 كلية طب عجبني شرحك جدا👌👌👌 go on and good like 🌺
You are awesome u just made this complicated cycle clear and easy thank you so much ❤️❤️❤️❤️
This guy is simply brilliant. Thank you very much. I wonder why the 33 guys disliked this video. Shame on them
Thanks sooo much..much love from Nigeria ♥️♥️
Thank you so much! You have helped me many times in my biochemistry exam! Actually, you helped me aced it. Thank you for organizing a comprehensive summary of topics like this one.
You are the GOAT AK.
So great, please thank you so much for all your lectures !!!!!!
u r amazing lecturer,u make topics easier......thank u so much
Your Videos are so amazingly good, thank you
admirable man right here, only the wisest spread wisdom for free :)
best videos so far, simple and detailed .. great job
Sir
Hats off to you, for such a beutifuly simplified Presentation
This will be great for my biochemistry revision thanks AK 47 :)!
No one teaches in details like he does
I just covered this in an hour. And I couldn't get it thru the whole year😂thank you
A simple thank you isn't enough for you sir❤️
great work..with a lot of clarity...THANK YOU AK
You are a very good lecturer...Thank you
Hello sir... I'm from India and ur lecture is quite easy to understand
I would like to have you as a biology chemistry professor. Your explanations are so clear and understandable. Thanks to much for your teaching. 🤓🤗👍
Thanks for helping get me through biochem in med school!!
thanks I dont understand this cycle but by you understand this cycle thanks a lot
Perfect ❤️ God bless you and reward you ❤️
There is one minor issue: inorganic pyrophosphate is quite stable at neutral pH and requires action of inorganic pyrophosphatase to convert it to two phosphates. Which is what happens. Without the action of inorganic pyrophosphatase, PPi would accumulate and inhibit many nucleotidyl transfer reactions, including those in nucleic acid synthesis. So 3 ATPs is what you need on the left-hand side of the urea cycle equation, not 4.
Inorganic pyrophosphatase is not an ATP-dependent enzyme, by the way.
He’s helping so much that I start to feel like I genuinely have a crush on him
Sir your way of teaching is really great..😊
Best and simplest easiest approach thanks
Sir you are so inteligent, love from pakistan
Quick question on the net rxn. I get that CO2 is converted to HCO3- using 1H2O but shouldn't the net rxn show the free H+ on the product side that disassociates from carbonic acid to form HCO3- or is it used somewhere and I haven't counted right?
Thank you, you are better than my teacher
great lecture . Simply explained . Thank you !
Your videos are Amazing ...You help so Many Individuals We appreciate You💙 What level videos are these videos ?? A level ...Pre med ?
Even though, I'm still not covered this topic yet, but I will view it, like it so you become famous
AK LECTURES
Just a very minor issue - it would have been nice, if you had included the regeneration of aspartate by the reaction of oxaloacetate (formed in the CAC from fumarate) with another a-aminoacid, forming aspartate and a a-ketoacid!
Anyway, thanks for your incredibly helpful lectures - they're amazing!
You're genius man ... keep going 💗
Better explanation than my professors
God bless you ✨ well Explained
Thanks for this explanation ✌🏼
Great!!!! Keep uploading perfect explanations.
You should sell " AK lectures T shirt ... people would buy it guarantee :)
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I fuckin love listening to you speak
your back again with new videos. your videos are interesting . thanks a lot man!
I love your videos.
Superb video as always... thank you so much!!!!
Youo have really impressed me. I can't hide it!
Thanks brother... You explained it nicely..
loving your lectures a lot....keep going....
Thanks! Will do my best!
@3.30 you said that the fumarate is the bridge between urea cycle and gluconeogenesis. Don't you mean the bridge between urea cycle and citric acid cycle? (Krebs bicycle?)
you saved my life
Thank you for the lecture!